Nuclear GPS for interchromosomal clustering.

Burns LT, Wente SR
Dev Cell. 2012 22 (6): 1119-20

PMID: 22698275 · PMCID: PMC3388979 · DOI:10.1016/j.devcel.2012.05.019

Nuclear architecture and the relative position of a gene can play roles in the regulation of its expression. In this issue of Developmental Cell, Brickner et al. (2012) analyze nuclear global positioning of genes and reveal that the Put3 transcription factor functions with cis-encoded DNA elements and nuclear pore complexes to regulate interchromosomal gene clustering.

Copyright © 2012 Elsevier Inc. All rights reserved.

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