Darinaparsin is a multivalent chemotherapeutic which induces incomplete stress response with disruption of microtubules and Shh signaling.

Mason TA, Kolobova E, Liu J, Roland JT, Chiang C, Goldenring JR
PLoS One. 2011 6 (11): e27699

PMID: 22110729 · PMCID: PMC3216988 · DOI:10.1371/journal.pone.0027699

MeSH Terms (16)

Animals Antineoplastic Agents Arsenicals Arsenites Cilia Glutathione Hedgehog Proteins HeLa Cells Humans Mice Microtubules NIH 3T3 Cells Polymerization Signal Transduction Sodium Compounds Stress, Physiological

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