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A reactive oxygen species (ROS)-degradable scaffold is fabricated by crosslinking biocompatible, hydrolytically-degradable poly(ε-caprolactone) (PCL) with a ROS-degradable oligoproline peptide, KPK. The ROS-mediated degradability triggers favorable host responses of the scaffold including improved cell infiltration and angiogenesis , indicating its unique advantages for tissue engineering applications.
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Released March 26, 2019