I started my research career in Vanderbilt after I got my Ph. D from the Institute of Hydrobiology, Chinese Academy of Sciences in 2005. When I arrived at Vanderbilt I first used Zebrafish to study the genetic signaling pathway that causes congenital cardiovascular diseases. In 2008, I joined the Magnuson lab as a research fellow in order to shift to mice as a model system. My project was to characterize the role of Insm1 in Islet development. I also made vectors that were used in RMCE experiments to generate mice for studying the transdifferentiation of acinar cells to pancreatic beta cells.
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Key: MeSH Term Keyword
Animals Bacteria Basic Helix-Loop-Helix Transcription Factors Bone Morphogenetic Protein 2 Bone Morphogenetic Protein 4 Calcium-Binding Proteins Carrier Proteins Chick Embryo Cloning, Molecular GATA5 Transcription Factor Gene Expression Regulation, Developmental Genes, Reporter In Situ Hybridization Insm1 Jagged-1 Protein Membrane Proteins Mice Morphogenesis Muscle Proteins Mutation Myocytes, Cardiac Nerve Tissue Proteins Oligonucleotides pancreatic differentiation Phenotype Receptor, Notch2 Repressor Proteins RNA, Ribosomal, 16S Soil Microbiology Versicans Zebrafish Zebrafish Proteins