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8-Hydroxy-2'-Deoxyguanosine Animals Azoxymethane Bone Transplantation Carcinogenesis Colitis Colitis, Ulcerative Colon Colorectal Neoplasms Deoxyguanosine Dextran Sulfate Diet DNA Damage Enterocytes Epidermal Growth Factor Female Gene Expression Regulation Humans Inflammation Intestinal Mucosa Mice Mice, Knockout Nuclear Proteins Repressor Proteins Signal Transduction Th1 Cells Transcription Factors Translocation, Genetic Tumor Suppressor Proteins Weight Loss