Philip Kingsley
Last active: 3/12/2020


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The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Aspects of Prostaglandin Glycerol Ester Biology. Kingsley PJ, Rouzer CA, Morgan AJ, Patel S, Marnett LJ (2019) Adv Exp Med Biol : 77-88
    › Primary publication · 31562623 (PubMed)
  2. IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain. Chopra S, Giovanelli P, Alvarado-Vazquez PA, Alonso S, Song M, Sandoval TA, Chae CS, Tan C, Fonseca MM, Gutierrez S, Jimenez L, Subbaramaiah K, Iwawaki T, Kingsley PJ, Marnett LJ, Kossenkov AV, Crespo MS, Dannenberg AJ, Glimcher LH, Romero-Sandoval EA, Cubillos-Ruiz JR (2019) Science 365(6450)
    › Primary publication · 31320508 (PubMed)
  3. Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer. Uddin MJ, Wilson AJ, Crews BC, Malerba P, Uddin MI, Kingsley PJ, Ghebreselasie K, Daniel CK, Nickels ML, Tantawy MN, Jashim E, Manning HC, Khabele D, Marnett LJ (2019) ACS Omega 4(5): 9251-9261
    › Primary publication · 31172046 (PubMed) · PMC6545551 (PubMed Central)
  4. The association between endogenous opioid function and morphine responsiveness: a moderating role for endocannabinoids. Bruehl S, Burns JW, Morgan A, Koltyn K, Gupta R, Buvanendran A, Edwards D, Chont M, Kingsley PJ, Marnett L, Stone A, Patel S (2019) Pain 160(3): 676-687
    › Primary publication · 30562268 (PubMed) · PMC6377294 (PubMed Central)
  5. Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling. Wepy JA, Galligan JJ, Kingsley PJ, Xu S, Goodman MC, Tallman KA, Rouzer CA, Marnett LJ (2019) J Lipid Res 60(2): 360-374
    › Primary publication · 30482805 (PubMed) · PMC6358295 (PubMed Central)
  6. Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks. Galligan JJ, Wepy JA, Streeter MD, Kingsley PJ, Mitchener MM, Wauchope OR, Beavers WN, Rose KL, Wang T, Spiegel DA, Marnett LJ (2018) Proc Natl Acad Sci U S A 115(37): 9228-9233
    › Primary publication · 30150385 (PubMed) · PMC6140490 (PubMed Central)
  7. Detection of Cyclooxygenase-2-Derived Oxygenation Products of the Endogenous Cannabinoid 2-Arachidonoylglycerol in Mouse Brain. Morgan AJ, Kingsley PJ, Mitchener MM, Altemus M, Patrick TA, Gaulden AD, Marnett LJ, Patel S (2018) ACS Chem Neurosci 9(7): 1552-1559
    › Primary publication · 29722963 (PubMed) · PMC6081739 (PubMed Central)
  8. Therapeutic endocannabinoid augmentation for mood and anxiety disorders: comparative profiling of FAAH, MAGL and dual inhibitors. Bedse G, Bluett RJ, Patrick TA, Romness NK, Gaulden AD, Kingsley PJ, Plath N, Marnett LJ, Patel S (2018) Transl Psychiatry 8(1): 92
    › Primary publication · 29695817 (PubMed) · PMC5917016 (PubMed Central)
  9. Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA. Wauchope OR, Mitchener MM, Beavers WN, Galligan JJ, Camarillo JM, Sanders WD, Kingsley PJ, Shim HN, Blackwell T, Luong T, deCaestecker M, Fessel JP, Marnett LJ (2018) Nucleic Acids Res 46(7): 3458-3467
    › Primary publication · 29438559 (PubMed) · PMC5909422 (PubMed Central)
  10. Functional Redundancy Between Canonical Endocannabinoid Signaling Systems in the Modulation of Anxiety. Bedse G, Hartley ND, Neale E, Gaulden AD, Patrick TA, Kingsley PJ, Uddin MJ, Plath N, Marnett LJ, Patel S (2017) Biol Psychiatry 82(7): 488-499
    › Primary publication · 28438413 (PubMed) · PMC5585044 (PubMed Central)
  11. Quantitative Analysis and Discovery of Lysine and Arginine Modifications. Galligan JJ, Kingsley PJ, Wauchope OR, Mitchener MM, Camarillo JM, Wepy JA, Harris PS, Fritz KS, Marnett LJ (2017) Anal Chem 89(2): 1299-1306
    › Primary publication · 27982582 (PubMed) · PMC5309163 (PubMed Central)
  12. Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors. Uddin MJ, Crews BC, Xu S, Ghebreselasie K, Daniel CK, Kingsley PJ, Banerjee S, Marnett LJ (2016) ACS Chem Biol 11(11): 3052-3060
    › Primary publication · 27588346 (PubMed) · PMC5289892 (PubMed Central)
  13. Functional Implications of Biochemical and Molecular Characteristics of Donation After Circulatory Death Livers. Masuzaki R, Yu H, Kingsley P, Marnett L, Zhao Z, Karp SJ (2015) Transplant Direct 1(5): e18
    › Primary publication · 27500220 (PubMed) · PMC4946467 (PubMed Central)
  14. Assay of Endocannabinoid Oxidation by Cyclooxygenase-2. Kudalkar SN, Kingsley PJ, Marnett LJ (2016) Methods Mol Biol : 205-15
    › Primary publication · 27245906 (PubMed) · PMC5289390 (PubMed Central)
  15. Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer. Uddin MJ, Werfel TA, Crews BC, Gupta MK, Kavanaugh TE, Kingsley PJ, Boyd K, Marnett LJ, Duvall CL (2016) Biomaterials : 71-80
    › Primary publication · 27043768 (PubMed) · PMC4833621 (PubMed Central)
  16. Cox-2-derived PGE2 induces Id1-dependent radiation resistance and self-renewal in experimental glioblastoma. Cook PJ, Thomas R, Kingsley PJ, Shimizu F, Montrose DC, Marnett LJ, Tabar VS, Dannenberg AJ, Benezra R (2016) Neuro Oncol 18(10): 1379-89
    › Primary publication · 27022132 (PubMed) · PMC5035519 (PubMed Central)
  17. Nuclear Oxidation of a Major Peroxidation DNA Adduct, M1dG, in the Genome. Wauchope OR, Beavers WN, Galligan JJ, Mitchener MM, Kingsley PJ, Marnett LJ (2015) Chem Res Toxicol 28(12): 2334-42
    › Primary publication · 26469224 (PubMed) · PMC4993022 (PubMed Central)
  18. Multitargeting of selected prostanoid receptors provides agents with enhanced anti-inflammatory activity in macrophages. Wang JW, Woodward DF, Martos JL, Cornell CL, Carling RW, Kingsley PJ, Marnett LJ (2016) FASEB J 30(1): 394-404
    › Primary publication · 26420849 (PubMed)
  19. Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe. Uddin MJ, Crews BC, Ghebreselasie K, Daniel CK, Kingsley PJ, Xu S, Marnett LJ (2015) J Biomed Opt 20(5): 50502
    › Primary publication · 25970082 (PubMed) · PMC4430360 (PubMed Central)
  20. 13-Methylarachidonic acid is a positive allosteric modulator of endocannabinoid oxygenation by cyclooxygenase. Kudalkar SN, Nikas SP, Kingsley PJ, Xu S, Galligan JJ, Rouzer CA, Banerjee S, Ji L, Eno MR, Makriyannis A, Marnett LJ (2015) J Biol Chem 290(12): 7897-909
    › Primary publication · 25648895 (PubMed) · PMC4367288 (PubMed Central)
  21. Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation. Shonesy BC, Bluett RJ, Ramikie TS, Báldi R, Hermanson DJ, Kingsley PJ, Marnett LJ, Winder DG, Colbran RJ, Patel S (2014) Cell Rep 9(5): 1644-1653
    › Primary publication · 25466252 (PubMed) · PMC4268380 (PubMed Central)
  22. Protein modification by adenine propenal. Shuck SC, Wauchope OR, Rose KL, Kingsley PJ, Rouzer CA, Shell SM, Sugitani N, Chazin WJ, Zagol-Ikapitte I, Boutaud O, Oates JA, Galligan JJ, Beavers WN, Marnett LJ (2014) Chem Res Toxicol 27(10): 1732-42
    › Primary publication · 25211669 (PubMed) · PMC4203390 (PubMed Central)
  23. Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes. Windsor MA, Hermanson DJ, Kingsley PJ, Xu S, Crews BC, Ho W, Keenan CM, Banerjee S, Sharkey KA, Marnett LJ (2012) ACS Med Chem Lett 3(9): 759-763
    › Primary publication · 22984634 (PubMed) · PMC3441040 (PubMed Central)
  24. Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold. Liedtke AJ, Crews BC, Daniel CM, Blobaum AL, Kingsley PJ, Ghebreselasie K, Marnett LJ (2012) J Med Chem 55(5): 2287-300
    › Primary publication · 22263894 (PubMed) · PMC3297362 (PubMed Central)
  25. Selection of monoclonal antibodies against 6-oxo-M(1)dG and their use in an LC-MS/MS assay for the presence of 6-oxo-M(1)dG in vivo. Akingbade D, Kingsley PJ, Shuck SC, Cooper T, Carnahan R, Szekely J, Marnett LJ (2012) Chem Res Toxicol 25(2): 454-61
    › Primary publication · 22211372 (PubMed) · PMC3285145 (PubMed Central)
  26. Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents. Uddin MJ, Crews BC, Blobaum AL, Kingsley PJ, Gorden DL, McIntyre JO, Matrisian LM, Subbaramaiah K, Dannenberg AJ, Piston DW, Marnett LJ (2010) Cancer Res 70(9): 3618-27
    › Primary publication · 20430759 (PubMed) · PMC2864539 (PubMed Central)
  27. Characterization of an AM404 analogue, N-(3-hydroxyphenyl)arachidonoylamide, as a substrate and inactivator of prostaglandin endoperoxide synthase. Turman MV, Kingsley PJ, Marnett LJ (2009) Biochemistry 48(51): 12233-41
    › Primary publication · 19928795 (PubMed) · PMC2797370 (PubMed Central)
  28. Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala. Patel S, Kingsley PJ, Mackie K, Marnett LJ, Winder DG (2009) Neuropsychopharmacology 34(13): 2699-709
    › Primary publication · 19675536 (PubMed) · PMC2881681 (PubMed Central)
  29. Analysis of endocannabinoids, their congeners and COX-2 metabolites. Kingsley PJ, Marnett LJ (2009) J Chromatogr B Analyt Technol Biomed Life Sci 877(26): 2746-54
    › Primary publication · 19505857 (PubMed) · PMC4903075 (PubMed Central)
  30. The influence of double bond geometry in the inhibition of cyclooxygenases by sulindac derivatives. Walters MJ, Blobaum AL, Kingsley PJ, Felts AS, Sulikowski GA, Marnett LJ (2009) Bioorg Med Chem Lett 19(12): 3271-4
    › Primary publication · 19427206 (PubMed) · PMC2760071 (PubMed Central)
  31. Genetic loss of Faah compromises male fertility in mice. Sun X, Wang H, Okabe M, Mackie K, Kingsley PJ, Marnett LJ, Cravatt BF, Dey SK (2009) Biol Reprod 80(2): 235-42
    › Primary publication · 18987328 (PubMed) · PMC2804815 (PubMed Central)
  32. Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine. Turman MV, Kingsley PJ, Rouzer CA, Cravatt BF, Marnett LJ (2008) Biochemistry 47(12): 3917-25
    › Primary publication · 18311922 (PubMed) · PMC2760074 (PubMed Central)
  33. LC-MS-MS analysis of neutral eicosanoids. Kingsley PJ, Marnett LJ (2007) Methods Enzymol : 91-112
    › Primary publication · 17954230 (PubMed)
  34. Induction and function of lipocalin prostaglandin D synthase in host immunity. Joo M, Kwon M, Sadikot RT, Kingsley PJ, Marnett LJ, Blackwell TS, Peebles RS, Urade Y, Christman JW (2007) J Immunol 179(4): 2565-75
    › Primary publication · 17675519 (PubMed)
  35. Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation. Wang H, Xie H, Sun X, Kingsley PJ, Marnett LJ, Cravatt BF, Dey SK (2007) Prostaglandins Other Lipid Mediat 83(1-2): 62-74
    › Primary publication · 17259073 (PubMed) · PMC1805469 (PubMed Central)
  36. Fatty acid amide hydrolase deficiency limits early pregnancy events. Wang H, Xie H, Guo Y, Zhang H, Takahashi T, Kingsley PJ, Marnett LJ, Das SK, Cravatt BF, Dey SK (2006) J Clin Invest 116(8): 2122-31
    › Primary publication · 16886060 (PubMed) · PMC1523389 (PubMed Central)
  37. Simultaneous analysis of prostaglandin glyceryl esters and prostaglandins by electrospray tandem mass spectrometry. Kingsley PJ, Rouzer CA, Saleh S, Marnett LJ (2005) Anal Biochem 343(2): 203-11
    › Primary publication · 16004953 (PubMed)
  38. N-acylphosphatidylethanolamine-hydrolyzing phospholipase D is an important determinant of uterine anandamide levels during implantation. Guo Y, Wang H, Okamoto Y, Ueda N, Kingsley PJ, Marnett LJ, Schmid HH, Das SK, Dey SK (2005) J Biol Chem 280(25): 23429-32
    › Primary publication · 15890658 (PubMed)
  39. RAW264.7 cells lack prostaglandin-dependent autoregulation of tumor necrosis factor-alpha secretion. Rouzer CA, Jacobs AT, Nirodi CS, Kingsley PJ, Morrow JD, Marnett LJ (2005) J Lipid Res 46(5): 1027-37
    › Primary publication · 15722559 (PubMed)
  40. Aberrant cannabinoid signaling impairs oviductal transport of embryos. Wang H, Guo Y, Wang D, Kingsley PJ, Marnett LJ, Das SK, DuBois RN, Dey SK (2004) Nat Med 10(10): 1074-80
    › Primary publication · 15378054 (PubMed)
  41. Cyclooxygenase-1-dependent prostaglandin synthesis modulates tumor necrosis factor-alpha secretion in lipopolysaccharide-challenged murine resident peritoneal macrophages. Rouzer CA, Kingsley PJ, Wang H, Zhang H, Morrow JD, Dey SK, Marnett LJ (2004) J Biol Chem 279(33): 34256-68
    › Primary publication · 15181007 (PubMed)
  42. Analysis of endocannabinoids by Ag+ coordination tandem mass spectrometry. Kingsley PJ, Marnett LJ (2003) Anal Biochem 314(1): 8-15
    › Primary publication · 12633597 (PubMed)
  43. Selective oxygenation of N-arachidonylglycine by cyclooxygenase-2. Prusakiewicz JJ, Kingsley PJ, Kozak KR, Marnett LJ (2002) Biochem Biophys Res Commun 296(3): 612-7
    › Primary publication · 12176025 (PubMed)