Dawei Wei
Last active: 11/7/2018


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The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Endogenous bradykinin and B1-B5 during angiotensin-converting enzyme inhibitor-associated angioedema. Hubers SA, Kohm K, Wei S, Yu C, Nian H, Grabert R, Sexton DJ, Brown NJ (2018) J Allergy Clin Immunol 142(5): 1636-1639.e5
    › Primary publication · 30036596 (PubMed) · PMC6226317 (PubMed Central)
  2. The Cytochrome P450 Slow Metabolizers CYP2C9*2 and CYP2C9*3 Directly Regulate Tumorigenesis via Reduced Epoxyeicosatrienoic Acid Production. Sausville LN, Gangadhariah MH, Chiusa M, Mei S, Wei S, Zent R, Luther JM, Shuey MM, Capdevila JH, Falck JR, Guengerich FP, Williams SM, Pozzi A (2018) Cancer Res 78(17): 4865-4877
    › Primary publication · 30012669 (PubMed) · PMC6125168 (PubMed Central)
  3. 7-ketocholesterol and 27-hydroxycholesterol decreased doxorubicin sensitivity in breast cancer cells: estrogenic activity and mTOR pathway. Wang CW, Huang CC, Chou PH, Chang YP, Wei S, Guengerich FP, Chou YC, Wang SF, Lai PS, Souček P, Ueng YF (2017) Oncotarget 8(39): 66033-66050
    › Primary publication · 29029490 (PubMed) · PMC5630390 (PubMed Central)
  4. Selective changes in cholesterol metabolite levels in plasma of breast cancer patients after tumor removal. Soucek P, Vrana D, Ueng YF, Wei S, Kozevnikovova R, Guengerich FP (2018) Clin Chem Lab Med 56(3): e78-e81
    › Primary publication · 28915107 (PubMed) · PMC5792305 (PubMed Central)
  5. Association of gain-of-function EPHX2 polymorphism Lys55Arg with acute kidney injury following cardiac surgery. Shuey MM, Billings FT, Wei S, Milne GL, Nian H, Yu C, Brown NJ (2017) PLoS One 12(5): e0175292
    › Primary publication · 28552948 (PubMed) · PMC5446112 (PubMed Central)
  6. 20-Hydroxyeicosatetraenoic Acid (HETE)-dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: NORMALIZATION OF BLOOD PRESSURE BY SODIUM RESTRICTION, HYDROCHLOROTHIAZIDE, OR BLOCKADE OF THE TYPE 1 ANGIOTENSIN II RECEPTOR. Savas Ü, Wei S, Hsu MH, Falck JR, Guengerich FP, Capdevila JH, Johnson EF (2016) J Biol Chem 291(32): 16904-19
    › Primary publication · 27298316 (PubMed) · PMC4974402 (PubMed Central)
  7. Targeting of splice variants of human cytochrome P450 2C8 (CYP2C8) to mitochondria and their role in arachidonic acid metabolism and respiratory dysfunction. Bajpai P, Srinivasan S, Ghosh J, Nagy LD, Wei S, Guengerich FP, Avadhani NG (2014) J Biol Chem 289(43): 29614-30
    › Primary publication · 25160618 (PubMed) · PMC4207977 (PubMed Central)
  8. Oxidation of endogenous N-arachidonoylserotonin by human cytochrome P450 2U1. Siller M, Goyal S, Yoshimoto FK, Xiao Y, Wei S, Guengerich FP (2014) J Biol Chem 289(15): 10476-10487
    › Primary publication · 24563460 (PubMed) · PMC4036169 (PubMed Central)
  9. PPARα activation can help prevent and treat non-small cell lung cancer. Skrypnyk N, Chen X, Hu W, Su Y, Mont S, Yang S, Gangadhariah M, Wei S, Falck JR, Jat JL, Zent R, Capdevila JH, Pozzi A (2014) Cancer Res 74(2): 621-31
    › Primary publication · 24302581 (PubMed) · PMC3902646 (PubMed Central)
  10. Role of epoxyeicosatrienoic acids (EETs) in mediation of dopamine's effects in the kidney. Zhang MZ, Wang Y, Yao B, Gewin L, Wei S, Capdevila JH, Harris RC (2013) Am J Physiol Renal Physiol 305(12): F1680-6
    › Primary publication · 24154693 (PubMed) · PMC3882452 (PubMed Central)
  11. Development of epoxyeicosatrienoic acid analogs with in vivo anti-hypertensive actions. Imig JD, Elmarakby A, Nithipatikom K, Wei S, Capdevila JH, Tuniki VR, Sangras B, Anjaiah S, Manthati VL, Sudarshan Reddy D, Falck JR (2010) Front Physiol : 157
    › Primary publication · 21423396 (PubMed) · PMC3059925 (PubMed Central)
  12. The arachidonic acid epoxygenase is a component of the signaling mechanisms responsible for VEGF-stimulated angiogenesis. Yang S, Wei S, Pozzi A, Capdevila JH (2009) Arch Biochem Biophys 489(1-2): 82-91
    › Primary publication · 19464254 (PubMed) · PMC3786555 (PubMed Central)
  13. Identification of novel endogenous cytochrome p450 arachidonate metabolites with high affinity for cannabinoid receptors. Chen JK, Chen J, Imig JD, Wei S, Hachey DL, Guthi JS, Falck JR, Capdevila JH, Harris RC (2008) J Biol Chem 283(36): 24514-24
    › Primary publication · 18606824 (PubMed) · PMC2528993 (PubMed Central)
  14. Peroxisomal proliferator-activated receptor-alpha-dependent inhibition of endothelial cell proliferation and tumorigenesis. Pozzi A, Ibanez MR, Gatica AE, Yang S, Wei S, Mei S, Falck JR, Capdevila JH (2007) J Biol Chem 282(24): 17685-95
    › Primary publication · 17405874 (PubMed)
  15. Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel. Nakagawa K, Holla VR, Wei Y, Wang WH, Gatica A, Wei S, Mei S, Miller CM, Cha DR, Price E, Zent R, Pozzi A, Breyer MD, Guan Y, Falck JR, Waterman MR, Capdevila JH (2006) J Clin Invest 116(6): 1696-702
    › Primary publication · 16691295 (PubMed) · PMC1459070 (PubMed Central)
  16. Chiral resolution of the epoxyeicosatrienoic acids, arachidonic acid epoxygenase metabolites. Wei S, Brittin JJ, Falck JR, Anjaiah S, Nithipatikom K, Cui L, Campbell WB, Capdevila JH (2006) Anal Biochem 352(1): 129-34
    › Primary publication · 16480681 (PubMed)
  17. Characterization of 5,6- and 8,9-epoxyeicosatrienoic acids (5,6- and 8,9-EET) as potent in vivo angiogenic lipids. Pozzi A, Macias-Perez I, Abair T, Wei S, Su Y, Zent R, Falck JR, Capdevila JH (2005) J Biol Chem 280(29): 27138-46
    › Primary publication · 15917237 (PubMed)
  18. Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation. Pozzi A, Yan X, Macias-Perez I, Wei S, Hata AN, Breyer RM, Morrow JD, Capdevila JH (2004) J Biol Chem 279(28): 29797-804
    › Primary publication · 15123663 (PubMed)
  19. The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands. Cowart LA, Wei S, Hsu MH, Johnson EF, Krishna MU, Falck JR, Capdevila JH (2002) J Biol Chem 277(38): 35105-12
    › Primary publication · 12124379 (PubMed)
  20. Epoxygenase metabolites contribute to nitric oxide-independent afferent arteriolar vasodilation in response to bradykinin. Imig JD, Falck JR, Wei S, Capdevila JH (2001) J Vasc Res 38(3): 247-55
    › Primary publication · 11399897 (PubMed)
  21. Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid. Imig JD, Zhao X, Falck JR, Wei S, Capdevila JH (2001) J Hypertens 19(5): 983-92
    › Primary publication · 11393683 (PubMed)
  22. A keratinocyte-specific epoxygenase, CYP2B12, metabolizes arachidonic acid with unusual selectivity, producing a single major epoxyeicosatrienoic acid. Keeney DS, Skinner C, Wei S, Friedberg T, Waterman MR (1998) J Biol Chem 273(15): 9279-84
    › Primary publication · 9535921 (PubMed)
  23. An active site substitution, F87V, converts cytochrome P450 BM-3 into a regio- and stereoselective (14S,15R)-arachidonic acid epoxygenase. Graham-Lorence S, Truan G, Peterson JA, Falck JR, Wei S, Helvig C, Capdevila JH (1997) J Biol Chem 272(2): 1127-35
    › Primary publication · 8995412 (PubMed)
  24. The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3. Capdevila JH, Wei S, Helvig C, Falck JR, Belosludtsev Y, Truan G, Graham-Lorence SE, Peterson JA (1996) J Biol Chem 271(37): 22663-71
    › Primary publication · 8798438 (PubMed)
  25. Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis. Zeldin DC, Wei S, Falck JR, Hammock BD, Snapper JR, Capdevila JH (1995) Arch Biochem Biophys 316(1): 443-51
    › Primary publication · 7840649 (PubMed)
  26. Arachidonic acid epoxygenase: structural characterization and quantification of epoxyeicosatrienoates in plasma. Karara A, Wei S, Spady D, Swift L, Capdevila JH, Falck JR (1992) Biochem Biophys Res Commun 182(3): 1320-5
    › Primary publication · 1540175 (PubMed)
  27. Resolution of dihydroxyeicosanoates and of dihydroxyeicosatrienoates by chiral phase chromatography. Capdevila JH, Wei S, Kumar A, Kobayashi J, Snapper JR, Zeldin DC, Bhatt RK, Falck JR (1992) Anal Biochem 207(2): 236-40
    › Primary publication · 1481976 (PubMed)
  28. Cytochrome P-450 arachidonic acid epoxygenase. Regulatory control of the renal epoxygenase by dietary salt loading. Capdevila JH, Wei S, Yan J, Karara A, Jacobson HR, Falck JR, Guengerich FP, DuBois RN (1992) J Biol Chem 267(30): 21720-6
    › Primary publication · 1400482 (PubMed)