Erkan Karakas
Last active: 3/18/2020


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The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist. Azumaya CM, Linton EA, Risener CJ, Nakagawa T, Karakas E (2020) J Biol Chem 295(6): 1743-1753
    › Primary publication · 31915246 (PubMed) · PMC7008357 (PubMed Central)
  2. Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors. Regan MC, Grant T, McDaniel MJ, Karakas E, Zhang J, Traynelis SF, Grigorieff N, Furukawa H (2018) Neuron 98(3): 521-529.e3
    › Primary publication · 29656875 (PubMed) · PMC5963293 (PubMed Central)
  3. Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain. Romero-Hernandez A, Simorowski N, Karakas E, Furukawa H (2016) Neuron 92(6): 1324-1336
    › Primary publication · 27916457 (PubMed) · PMC5182123 (PubMed Central)
  4. Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Tajima N, Karakas E, Grant T, Simorowski N, Diaz-Avalos R, Grigorieff N, Furukawa H (2016) Nature 534(7605): 63-8
    › Primary publication · 27135925 (PubMed) · PMC5136294 (PubMed Central)
  5. Emerging structural insights into the function of ionotropic glutamate receptors. Karakas E, Regan MC, Furukawa H (2015) Trends Biochem Sci 40(6): 328-37
    › Primary publication · 25941168 (PubMed) · PMC4464829 (PubMed Central)
  6. Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator. Khatri A, Burger PB, Swanger SA, Hansen KB, Zimmerman S, Karakas E, Liotta DC, Furukawa H, Snyder JP, Traynelis SF (2014) Mol Pharmacol 86(5): 548-60
    › Primary publication · 25205677 (PubMed) · PMC4201136 (PubMed Central)
  7. Crystal structure of a heterotetrameric NMDA receptor ion channel. Karakas E, Furukawa H (2014) Science 344(6187): 992-7
    › Primary publication · 24876489 (PubMed) · PMC4113085 (PubMed Central)
  8. Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators. Burger PB, Yuan H, Karakas E, Geballe M, Furukawa H, Liotta DC, Snyder JP, Traynelis SF (2012) Mol Pharmacol 82(2): 344-59
    › Primary publication · 22596351 (PubMed) · PMC3400845 (PubMed Central)
  9. Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Karakas E, Simorowski N, Furukawa H (2011) Nature 475(7355): 249-53
    › Primary publication · 21677647 (PubMed) · PMC3171209 (PubMed Central)
  10. Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit. Karakas E, Simorowski N, Furukawa H (2009) EMBO J 28(24): 3910-20
    › Primary publication · 19910922 (PubMed) · PMC2797058 (PubMed Central)
  11. Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad. Karakas E, Truglio JJ, Croteau D, Rhau B, Wang L, Van Houten B, Kisker C (2007) EMBO J 26(2): 613-22
    › Primary publication · 17245438 (PubMed) · PMC1783470 (PubMed Central)
  12. Structural basis for DNA recognition and processing by UvrB. Truglio JJ, Karakas E, Rhau B, Wang H, DellaVecchia MJ, Van Houten B, Kisker C (2006) Nat Struct Mol Biol 13(4): 360-4
    › Primary publication · 16532007 (PubMed)
  13. Structural analysis of missense mutations causing isolated sulfite oxidase deficiency. Karakas E, Kisker C (2005) Dalton Trans (21): 3459-63
    › Primary publication · 16234925 (PubMed)
  14. Structural insights into sulfite oxidase deficiency. Karakas E, Wilson HL, Graf TN, Xiang S, Jaramillo-Busquets S, Rajagopalan KV, Kisker C (2005) J Biol Chem 280(39): 33506-15
    › Primary publication · 16048997 (PubMed)
  15. Structural insights into the first incision reaction during nucleotide excision repair. Truglio JJ, Rhau B, Croteau DL, Wang L, Skorvaga M, Karakas E, DellaVecchia MJ, Wang H, Van Houten B, Kisker C (2005) EMBO J 24(5): 885-94
    › Primary publication · 15692561 (PubMed) · PMC554121 (PubMed Central)