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Allosteric Regulation Antineoplastic Agents Antipsychotic Agents Brain Brain Mapping Calcium Drug Evaluation, Preclinical Extracellular Space Female Fluorodeoxyglucose F18 Functional Laterality Gene Expression Profiling Hindlimb Suspension Hyperkinesis Mice, Transgenic Microscopy, Electron, Transmission Muscle Strength Neural Conduction Oxygen Prefrontal Cortex Protein Serine-Threonine Kinases Psychomotor Performance Rats, Sprague-Dawley Receptor, Metabotropic Glutamate 5 Receptor, Muscarinic M4 Reverse Transcriptase Polymerase Chain Reaction Schwann Cells Signal Processing, Computer-Assisted Signal Transduction Tomography, X-Ray Computed