Donald Stec
Faculty Member
Last active: 3/3/2020


None provided


The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. The toxin goniodomin, produced by Alexandrium spp., is identical to goniodomin A. Harris CM, Reece KS, Stec DF, Scott GP, Jones WM, Hobbs PLM, Harris TM (2020) Harmful Algae : 101707
    › Primary publication · 32113590 (PubMed)
  2. Algal Toxin Goniodomin A Binds Potassium Ion Selectively to Yield a Conformationally Altered Complex with Potential Biological Consequences. Tainter CJ, Schley ND, Harris CM, Stec DF, Song AK, Balinski A, May JC, McLean JA, Reece KS, Harris TM (2020) J Nat Prod 83(4): 1069-1081
    › Primary publication · 32083860 (PubMed)
  3. SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M PAMs. Chopko TC, Han C, Gregro AR, Engers DW, Felts AS, Poslusney MS, Bollinger KA, Morrison RD, Bubser M, Lamsal A, Luscombe VB, Cho HP, Schnetz-Boutaud NC, Rodriguez AL, Chang S, Daniels JS, Stec DF, Niswender CM, Jones CK, Wood MR, Wood MW, Duggan ME, Brandon NJ, Conn PJ, Bridges TM, Lindsley CW, Melancon BJ (2019) Bioorg Med Chem Lett 29(16): 2224-2228
    › Primary publication · 31248774 (PubMed) · PMC6690795 (PubMed Central)
  4. Changes in urinary metabolome related to body fat involve intermediates of choline processing by gut microbiota. Stec DF, Henry C, Stec DE, Voziyan P (2019) Heliyon 5(4): e01497
    › Primary publication · 31011651 (PubMed) · PMC6465582 (PubMed Central)
  5. Absolute Configurations of Naturally Occurring [5]- and [3]-Ladderanoic Acids: Isolation, Chiroptical Spectroscopy, and Crystallography. Raghavan V, Johnson JL, Stec DF, Song B, Zajac G, Baranska M, Harris CM, Schley ND, Polavarapu PL, Harris TM (2018) J Nat Prod 81(12): 2654-2666
    › Primary publication · 30562024 (PubMed)
  6. 5'-O-Alkylpyridoxamines: Lipophilic Analogues of Pyridoxamine Are Potent Scavengers of 1,2-Dicarbonyls. Amarnath V, Amarnath K, Avance J, Stec DF, Voziyan P (2015) Chem Res Toxicol 28(7): 1469-75
    › Primary publication · 26046387 (PubMed) · PMC4996123 (PubMed Central)
  7. Alterations of urinary metabolite profile in model diabetic nephropathy. Stec DF, Wang S, Stothers C, Avance J, Denson D, Harris R, Voziyan P (2015) Biochem Biophys Res Commun 456(2): 610-4
    › Primary publication · 25499815 (PubMed) · PMC4287263 (PubMed Central)
  8. Assay of protein and peptide adducts of cholesterol ozonolysis products by hydrophobic and click enrichment methods. Windsor K, Genaro-Mattos TC, Miyamoto S, Stec DF, Kim HY, Tallman KA, Porter NA (2014) Chem Res Toxicol 27(10): 1757-68
    › Primary publication · 25185119 (PubMed) · PMC4203397 (PubMed Central)
  9. Characterization of the deoxyguanosine-lysine cross-link of methylglyoxal. Petrova KV, Millsap AD, Stec DF, Rizzo CJ (2014) Chem Res Toxicol 27(6): 1019-29
    › Primary publication · 24801980 (PubMed) · PMC4060920 (PubMed Central)
  10. Isolation and characterization of two geometric allene oxide isomers synthesized from 9S-hydroperoxylinoleic acid by cytochrome P450 CYP74C3: stereochemical assignment of natural fatty acid allene oxides. Brash AR, Boeglin WE, Stec DF, Voehler M, Schneider C, Cha JK (2013) J Biol Chem 288(29): 20797-20806
    › Primary publication · 23709224 (PubMed) · PMC3774351 (PubMed Central)
  11. Straightforward protocol for the efficient synthesis of varied N(1)-acylated (aza)indole 2-/3-alkanoic acids and esters: optimization and scale-up. Liedtke AJ, Kim K, Stec DF, Sulikowski GA, Marnett LJ (2012) Tetrahedron 68(48): 10049-10058
    › Primary publication · 23204595 (PubMed) · PMC3509943 (PubMed Central)
  12. Synthesis of bacillithiol and the catalytic selectivity of FosB-type fosfomycin resistance proteins. Lamers AP, Keithly ME, Kim K, Cook PD, Stec DF, Hines KM, Sulikowski GA, Armstrong RN (2012) Org Lett 14(20): 5207-9
    › Primary publication · 23030527 (PubMed) · PMC3544479 (PubMed Central)
  13. The role of aldehyde oxidase and xanthine oxidase in the biotransformation of a novel negative allosteric modulator of metabotropic glutamate receptor subtype 5. Morrison RD, Blobaum AL, Byers FW, Santomango TS, Bridges TM, Stec D, Brewer KA, Sanchez-Ponce R, Corlew MM, Rush R, Felts AS, Manka J, Bates BS, Venable DF, Rodriguez AL, Jones CK, Niswender CM, Conn PJ, Lindsley CW, Emmitte KA, Daniels JS (2012) Drug Metab Dispos 40(9): 1834-45
    › Primary publication · 22711749 (PubMed) · PMC3422546 (PubMed Central)
  14. Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2). Prage EB, Morgenstern R, Jakobsson PJ, Stec DF, Voehler MW, Armstrong RN (2012) Biochemistry 51(11): 2348-56
    › Primary publication · 22356188 (PubMed) · PMC3773687 (PubMed Central)
  15. Deoxyguanosine forms a bis-adduct with E,E-muconaldehyde, an oxidative metabolite of benzene: implications for the carcinogenicity of benzene. Harris CM, Stec DF, Christov PP, Kozekov ID, Rizzo CJ, Harris TM (2011) Chem Res Toxicol 24(11): 1944-56
    › Primary publication · 21972945 (PubMed) · PMC3408037 (PubMed Central)
  16. Glucose autoxidation induces functional damage to proteins via modification of critical arginine residues. Chetyrkin S, Mathis M, Pedchenko V, Sanchez OA, McDonald WH, Hachey DL, Madu H, Stec D, Hudson B, Voziyan P (2011) Biochemistry 50(27): 6102-12
    › Primary publication · 21661747 (PubMed) · PMC3140462 (PubMed Central)
  17. Synthesis of the four stereoisomers of 2,3-epoxy-4-hydroxynonanal and their reactivity with deoxyguanosine. Petrova KV, Stec DF, Voehler M, Rizzo CJ (2011) Org Biomol Chem 9(6): 1960-71
    › Primary publication · 21258716 (PubMed) · PMC3694406 (PubMed Central)
  18. The IsdG-family of haem oxygenases degrades haem to a novel chromophore. Reniere ML, Ukpabi GN, Harry SR, Stec DF, Krull R, Wright DW, Bachmann BO, Murphy ME, Skaar EP (2010) Mol Microbiol 75(6): 1529-38
    › Primary publication · 20180905 (PubMed) · PMC3800195 (PubMed Central)
  19. Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases. Zhang H, Bren U, Kozekov ID, Rizzo CJ, Stec DF, Guengerich FP (2009) J Mol Biol 392(2): 251-69
    › Primary publication · 19607842 (PubMed) · PMC2755575 (PubMed Central)
  20. Cooperativity in oxidation reactions catalyzed by cytochrome P450 1A2: highly cooperative pyrene hydroxylation and multiphasic kinetics of ligand binding. Sohl CD, Isin EM, Eoff RL, Marsch GA, Stec DF, Guengerich FP (2008) J Biol Chem 283(11): 7293-308
    › Primary publication · 18187423 (PubMed)
  21. Enzymatic synthesis of a bicyclobutane fatty acid by a hemoprotein lipoxygenase fusion protein from the cyanobacterium Anabaena PCC 7120. Schneider C, Niisuke K, Boeglin WE, Voehler M, Stec DF, Porter NA, Brash AR (2007) Proc Natl Acad Sci U S A 104(48): 18941-5
    › Primary publication · 18025466 (PubMed) · PMC2141887 (PubMed Central)
  22. Identification of the peroxidation products of 13-hydroxy-gamma-linolenate and 15-hydroxyarachidonate: mechanistic studies on the formation of leukotriene-like diols. Rector CL, Stec DF, Brash AR, Porter NA (2007) Chem Res Toxicol 20(11): 1582-93
    › Primary publication · 17907784 (PubMed)
  23. Synthesis of nucleotide analogues by a promiscuous phosphoribosyltransferase. Scism RA, Stec DF, Bachmann BO (2007) Org Lett 9(21): 4179-82
    › Primary publication · 17854193 (PubMed)
  24. Metabolism in vitro and in vivo of the DNA base adduct, M1G. Knutson CG, Akingbade D, Crews BC, Voehler M, Stec DF, Marnett LJ (2007) Chem Res Toxicol 20(3): 550-7
    › Primary publication · 17311424 (PubMed)
  25. Convergent oxygenation of arachidonic acid by 5-lipoxygenase and cyclooxygenase-2. Schneider C, Boeglin WE, Yin H, Stec DF, Voehler M (2006) J Am Chem Soc 128(3): 720-1
    › Primary publication · 16417352 (PubMed) · PMC2532595 (PubMed Central)
  26. Trimethylsilylated allyl complexes of nickel. The stabilized bis(pi-allyl)nickel complex [eta3-1,3-(SiMe3)2C3H3]2Ni and its mono(pi-allyl)NiX (X=Br, I) derivatives. Quisenberry KT, Smith JD, Voehler M, Stec DF, Hanusa TP, Brennessel WW (2005) J Am Chem Soc 127(12): 4376-87
    › Primary publication · 15783220 (PubMed)