Jessica Overstreet
Last active: 7/27/2018


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The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Loss of tumour suppressor PTEN expression in renal injury initiates SMAD3- and p53-dependent fibrotic responses. Samarakoon R, Helo S, Dobberfuhl AD, Khakoo NS, Falke L, Overstreet JM, Goldschmeding R, Higgins PJ (2015) J Pathol 236(4): 421-32
    › Primary publication · 25810340 (PubMed) · PMC4509814 (PubMed Central)
  2. Tumor suppressor ataxia telangiectasia mutated functions downstream of TGF-β1 in orchestrating profibrotic responses. Overstreet JM, Samarakoon R, Cardona-Grau D, Goldschmeding R, Higgins PJ (2015) FASEB J 29(4): 1258-68
    › Primary publication · 25480384 (PubMed) · PMC4396616 (PubMed Central)
  3. Redox control of p53 in the transcriptional regulation of TGF-β1 target genes through SMAD cooperativity. Overstreet JM, Samarakoon R, Meldrum KK, Higgins PJ (2014) Cell Signal 26(7): 1427-36
    › Primary publication · 24613410 (PubMed) · PMC4048950 (PubMed Central)
  4. Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species. Samarakoon R, Dobberfuhl AD, Cooley C, Overstreet JM, Patel S, Goldschmeding R, Meldrum KK, Higgins PJ (2013) Cell Signal 25(11): 2198-209
    › Primary publication · 23872073 (PubMed)
  5. Ureteral Obstruction-Induced Renal Fibrosis: An In Vivo Platform for Mechanistic Discovery and Therapeutic Intervention. Dobberfuhl AD, Samarakoon R, Higgins CE, Mian BM, Overstreet JM, Higgins SP, Kogan BA, Higgins PJ (2012) Cell Dev Biol 1(3)
    › Primary publication · 23264954 (PubMed) · PMC3526117 (PubMed Central)
  6. TGF-β signaling in tissue fibrosis: redox controls, target genes and therapeutic opportunities. Samarakoon R, Overstreet JM, Higgins PJ (2013) Cell Signal 25(1): 264-8
    › Primary publication · 23063463 (PubMed) · PMC3508263 (PubMed Central)
  7. PAI-1: An Integrator of Cell Signaling and Migration. Czekay RP, Wilkins-Port CE, Higgins SP, Freytag J, Overstreet JM, Klein RM, Higgins CE, Samarakoon R, Higgins PJ (2011) Int J Cell Biol : 562481
    › Primary publication · 21837240 (PubMed) · PMC3151495 (PubMed Central)
  8. TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis. Samarakoon R, Overstreet JM, Higgins SP, Higgins PJ (2012) Cell Tissue Res 347(1): 117-28
    › Primary publication · 21638209 (PubMed) · PMC3188682 (PubMed Central)