Sara Van Driest
Last active: 4/11/2017


None provided


The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data. Mosley JD, van Driest SL, Wells QS, Shaffer CM, Edwards TL, Bastarache L, McCarty CA, Thompson W, Chute CG, Jarvik GP, Crosslin DR, Larson EB, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Denny JC, Roden DM (2016) Circ Cardiovasc Genet 9(6): 521-530
    › Primary publication · 27780847 (PubMed) · PMC5177499 (PubMed Central)
  2. Developing an Algorithm to Detect Early Childhood Obesity in Two Tertiary Pediatric Medical Centers. Lingren T, Thaker V, Brady C, Namjou B, Kennebeck S, Bickel J, Patibandla N, Ni Y, Van Driest SL, Chen L, Roach A, Cobb B, Kirby J, Denny J, Bailey-Davis L, Williams MS, Marsolo K, Solti I, Holm IA, Harley J, Kohane IS, Savova G, Crimmins N (2016) Appl Clin Inform 7(3): 693-706
    › Primary publication · 27452794 (PubMed) · PMC5052543 (PubMed Central)
  3. Pragmatic pharmacology: population pharmacokinetic analysis of fentanyl using remnant samples from children after cardiac surgery. Van Driest SL, Marshall MD, Hachey B, Beck C, Crum K, Owen J, Smith AH, Kannankeril PJ, Woodworth A, Caprioli RM, Choi L (2016) Br J Clin Pharmacol 81(6): 1165-74
    › Primary publication · 26861166 (PubMed) · PMC4876191 (PubMed Central)
  4. Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records. Van Driest SL, Wells QS, Stallings S, Bush WS, Gordon A, Nickerson DA, Kim JH, Crosslin DR, Jarvik GP, Carrell DS, Ralston JD, Larson EB, Bielinski SJ, Olson JE, Ye Z, Kullo IJ, Abul-Husn NS, Scott SA, Bottinger E, Almoguera B, Connolly J, Chiavacci R, Hakonarson H, Rasmussen-Torvik LJ, Pan V, Persell SD, Smith M, Chisholm RL, Kitchner TE, He MM, Brilliant MH, Wallace JR, Doheny KF, Shoemaker MB, Li R, Manolio TA, Callis TE, Macaya D, Williams MS, Carey D, Kapplinger JD, Ackerman MJ, Ritchie MD, Denny JC, Roden DM (2016) JAMA 315(1): 47-57
    › Primary publication · 26746457 (PubMed) · PMC4758131 (PubMed Central)
  5. Acute Kidney Injury Incidence in Noncritically Ill Hospitalized Children, Adolescents, and Young Adults: A Retrospective Observational Study. McGregor TL, Jones DP, Wang L, Danciu I, Bridges BC, Fleming GM, Shirey-Rice J, Chen L, Byrne DW, Van Driest SL (2016) Am J Kidney Dis 67(3): 384-90
    › Primary publication · 26319754 (PubMed) · PMC4769119 (PubMed Central)
  6. Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia. Karol SE, Yang W, Van Driest SL, Chang TY, Kaste S, Bowton E, Basford M, Bastarache L, Roden DM, Denny JC, Larsen E, Winick N, Carroll WL, Cheng C, Pei D, Fernandez CA, Liu C, Smith C, Loh ML, Raetz EA, Hunger SP, Scheet P, Jeha S, Pui CH, Evans WE, Devidas M, Mattano LA, Relling MV (2015) Blood 126(15): 1770-6
    › Primary publication · 26265699 (PubMed) · PMC4600016 (PubMed Central)
  7. Attitudes of clinicians following large-scale pharmacogenomics implementation. Peterson JF, Field JR, Shi Y, Schildcrout JS, Denny JC, McGregor TL, Van Driest SL, Pulley JM, Lubin IM, Laposata M, Roden DM, Clayton EW (2016) Pharmacogenomics J 16(4): 393-8
    › Primary publication · 26261062 (PubMed) · PMC4751074 (PubMed Central)
  8. A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough. Mosley JD, Shaffer CM, Van Driest SL, Weeke PE, Wells QS, Karnes JH, Velez Edwards DR, Wei WQ, Teixeira PL, Bastarache L, Crawford DC, Li R, Manolio TA, Bottinger EP, McCarty CA, Linneman JG, Brilliant MH, Pacheco JA, Thompson W, Chisholm RL, Jarvik GP, Crosslin DR, Carrell DS, Baldwin E, Ralston J, Larson EB, Grafton J, Scrol A, Jouni H, Kullo IJ, Tromp G, Borthwick KM, Kuivaniemi H, Carey DJ, Ritchie MD, Bradford Y, Verma SS, Chute CG, Veluchamy A, Siddiqui MK, Palmer CN, Doney A, MahmoudPour SH, Maitland-van der Zee AH, Morris AD, Denny JC, Roden DM (2016) Pharmacogenomics J 16(3): 231-7
    › Primary publication · 26169577 (PubMed) · PMC4713364 (PubMed Central)
  9. Phenotype-Driven Plasma Biobanking Strategies and Methods. Bowton EA, Collier SP, Wang X, Sutcliffe CB, Van Driest SL, Couch LJ, Herrera M, Jerome RN, Slebos RJ, Alborn WE, Liebler DC, McNaughton CD, Mernaugh RL, Wells QS, Brown NJ, Roden DM, Pulley JM (2015) J Pers Med 5(2): 140-52
    › Primary publication · 26110578 (PubMed) · PMC4493492 (PubMed Central)
  10. Genome-Wide Association Study of Serum Creatinine Levels during Vancomycin Therapy. Van Driest SL, McGregor TL, Velez Edwards DR, Saville BR, Kitchner TE, Hebbring SJ, Brilliant M, Jouni H, Kullo IJ, Creech CB, Kannankeril PJ, Vear SI, Brothers KB, Bowton EA, Shaffer CM, Patel N, Delaney JT, Bradford Y, Wilson S, Olson LM, Crawford DC, Potts AL, Ho RH, Roden DM, Denny JC (2015) PLoS One 10(6): e0127791
    › Primary publication · 26030142 (PubMed) · PMC4452656 (PubMed Central)
  11. Association between perioperative dexmedetomidine and arrhythmias after surgery for congenital heart disease. Shuplock JM, Smith AH, Owen J, Van Driest SL, Marshall M, Saville B, Xu M, Radbill AE, Fish FA, Kannankeril PJ (2015) Circ Arrhythm Electrophysiol 8(3): 643-50
    › Primary publication · 25878324 (PubMed) · PMC4472529 (PubMed Central)
  12. Pharmacogenomics: personalizing pediatric heart transplantation. Van Driest SL, Webber SA (2015) Circulation 131(5): 503-12
    › Primary publication · 25645611 (PubMed) · PMC4318121 (PubMed Central)
  13. Genotype and risk of major bleeding during warfarin treatment. Kawai VK, Cunningham A, Vear SI, Van Driest SL, Oginni A, Xu H, Jiang M, Li C, Denny JC, Shaffer C, Bowton E, Gage BF, Ray WA, Roden DM, Stein CM (2014) Pharmacogenomics 15(16): 1973-83
    › Primary publication · 25521356 (PubMed) · PMC4304738 (PubMed Central)
  14. A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record. Karnes JH, Cronin RM, Rollin J, Teumer A, Pouplard C, Shaffer CM, Blanquicett C, Bowton EA, Cowan JD, Mosley JD, Van Driest SL, Weeke PE, Wells QS, Bakchoul T, Denny JC, Greinacher A, Gruel Y, Roden DM (2015) Thromb Haemost 113(4): 772-81
    › Primary publication · 25503805 (PubMed) · PMC4433536 (PubMed Central)
  15. Integrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associations. Mosley JD, Van Driest SL, Weeke PE, Delaney JT, Wells QS, Bastarache L, Roden DM, Denny JC (2014) PLoS One 9(6): e100322
    › Primary publication · 24949630 (PubMed) · PMC4065041 (PubMed Central)
  16. Return of genomic results to research participants: the floor, the ceiling, and the choices in between. Jarvik GP, Amendola LM, Berg JS, Brothers K, Clayton EW, Chung W, Evans BJ, Evans JP, Fullerton SM, Gallego CJ, Garrison NA, Gray SW, Holm IA, Kullo IJ, Lehmann LS, McCarty C, Prows CA, Rehm HL, Sharp RR, Salama J, Sanderson S, Van Driest SL, Williams MS, Wolf SM, Wolf WA, eMERGE Act-ROR Committee and CERC Committee, CSER Act-ROR Working Group, Burke W (2014) Am J Hum Genet 94(6): 818-26
    › Primary publication · 24814192 (PubMed) · PMC4121476 (PubMed Central)
  17. Biobanks and electronic medical records: enabling cost-effective research. Bowton E, Field JR, Wang S, Schildcrout JS, Van Driest SL, Delaney JT, Cowan J, Weeke P, Mosley JD, Wells QS, Karnes JH, Shaffer C, Peterson JF, Denny JC, Roden DM, Pulley JM (2014) Sci Transl Med 6(234): 234cm3
    › Primary publication · 24786321 (PubMed) · PMC4226414 (PubMed Central)
  18. Response to "clinically actionable genotypes among Brazilians". Van Driest SL, Roden DM (2014) Clin Pharmacol Ther 96(1): 26
    › Primary publication · 24682028 (PubMed)
  19. The impact of age and CYP2C9 and VKORC1 variants on stable warfarin dose in the paediatric population. Vear SI, Ayers GD, Van Driest SL, Sidonio RF, Stein CM, Ho RH (2014) Br J Haematol 165(6): 832-5
    › Primary publication · 24601977 (PubMed) · PMC4043918 (PubMed Central)
  20. Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome. Weeke P, Mosley JD, Hanna D, Delaney JT, Shaffer C, Wells QS, Van Driest S, Karnes JH, Ingram C, Guo Y, Shyr Y, Norris K, Kannankeril PJ, Ramirez AH, Smith JD, Mardis ER, Nickerson D, George AL, Roden DM (2014) J Am Coll Cardiol 63(14): 1430-7
    › Primary publication · 24561134 (PubMed) · PMC4018823 (PubMed Central)
  21. Pharmacogenetics in clinical pediatrics: challenges and strategies. Van Driest SL, McGregor TL (2013) Per Med 10(7)
    › Primary publication · 24363766 (PubMed) · PMC3866691 (PubMed Central)
  22. Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data. Mosley JD, Van Driest SL, Larkin EK, Weeke PE, Witte JS, Wells QS, Karnes JH, Guo Y, Bastarache L, Olson LM, McCarty CA, Pacheco JA, Jarvik GP, Carrell DS, Larson EB, Crosslin DR, Kullo IJ, Tromp G, Kuivaniemi H, Carey DJ, Ritchie MD, Denny JC, Roden DM (2013) PLoS One 8(12): e81503
    › Primary publication · 24349080 (PubMed) · PMC3861317 (PubMed Central)
  23. Using systems approaches to address challenges for clinical implementation of pharmacogenomics. Karnes JH, Van Driest S, Bowton EA, Weeke PE, Mosley JD, Peterson JF, Denny JC, Roden DM (2014) Wiley Interdiscip Rev Syst Biol Med 6(2): 125-35
    › Primary publication · 24319008 (PubMed) · PMC3944797 (PubMed Central)
  24. Clinically actionable genotypes among 10,000 patients with preemptive pharmacogenomic testing. Van Driest SL, Shi Y, Bowton EA, Schildcrout JS, Peterson JF, Pulley J, Denny JC, Roden DM (2014) Clin Pharmacol Ther 95(4): 423-31
    › Primary publication · 24253661 (PubMed) · PMC3961508 (PubMed Central)
  25. Opioid use after cardiac surgery in children with Down syndrome. Van Driest SL, Shah A, Marshall MD, Xu H, Smith AH, McGregor TL, Kannankeril PJ (2013) Pediatr Crit Care Med 14(9): 862-8
    › Primary publication · 23962833 (PubMed) · PMC3830692 (PubMed Central)
  26. QT variability during initial exposure to sotalol: experience based on a large electronic medical record. Weeke P, Delaney J, Mosley JD, Wells Q, Van Driest S, Norris K, Kucera G, Stubblefield T, Roden DM (2013) Europace 15(12): 1791-7
    › Primary publication · 23787903 (PubMed) · PMC3888125 (PubMed Central)
  27. Inclusion of pediatric samples in an opt-out biorepository linking DNA to de-identified medical records: pediatric BioVU. McGregor TL, Van Driest SL, Brothers KB, Bowton EA, Muglia LJ, Roden DM (2013) Clin Pharmacol Ther 93(2): 204-11
    › Primary publication · 23281421 (PubMed) · PMC3686097 (PubMed Central)
  28. Mapping the incidentalome: estimating incidental findings generated through clinical pharmacogenomics testing. Westbrook MJ, Wright MF, Van Driest SL, McGregor TL, Denny JC, Zuvich RL, Clayton EW, Brothers KB (2013) Genet Med 15(5): 325-31
    › Primary publication · 23196672 (PubMed) · PMC3648626 (PubMed Central)
  29. Relationship of maternal vitamin D level with maternal and infant respiratory disease. Carroll KN, Gebretsadik T, Larkin EK, Dupont WD, Liu Z, Van Driest S, Hartert TV (2011) Am J Obstet Gynecol 205(3): 215.e1-7
    › Primary publication · 21658670 (PubMed) · PMC3171620 (PubMed Central)
  30. Echocardiography-guided genetic testing in hypertrophic cardiomyopathy: septal morphological features predict the presence of myofilament mutations. Binder J, Ommen SR, Gersh BJ, Van Driest SL, Tajik AJ, Nishimura RA, Ackerman MJ (2006) Mayo Clin Proc 81(4): 459-67
    › Primary publication · 16610565 (PubMed)
  31. Are longitudinal, natural history studies the next step in genotype-phenotype translational genomics in hypertrophic cardiomyopathy? Ackerman MJ, Van Driest SL, Bos M (2005) J Am Coll Cardiol 46(9): 1744-6
    › Primary publication · 16256879 (PubMed)
  32. Gene-specific modifying effects of pro-LVH polymorphisms involving the renin-angiotensin-aldosterone system among 389 unrelated patients with hypertrophic cardiomyopathy. Perkins MJ, Van Driest SL, Ellsworth EG, Will ML, Gersh BJ, Ommen SR, Ackerman MJ (2005) Eur Heart J 26(22): 2457-62
    › Primary publication · 16087648 (PubMed)
  33. Yield of genetic testing in hypertrophic cardiomyopathy. Van Driest SL, Ommen SR, Tajik AJ, Gersh BJ, Ackerman MJ (2005) Mayo Clin Proc 80(6): 739-44
    › Primary publication · 15945527 (PubMed)
  34. Molecular and functional characterization of a human frataxin mutation found in hypertrophic cardiomyopathy. Van Driest SL, Gakh O, Ommen SR, Isaya G, Ackerman MJ (2005) Mol Genet Metab 85(4): 280-5
    › Primary publication · 15936968 (PubMed)
  35. Sarcomeric genotyping in hypertrophic cardiomyopathy. Van Driest SL, Ommen SR, Tajik AJ, Gersh BJ, Ackerman MJ (2005) Mayo Clin Proc 80(4): 463-9
    › Primary publication · 15819282 (PubMed)
  36. Myosin binding protein C mutations and compound heterozygosity in hypertrophic cardiomyopathy. Van Driest SL, Vasile VC, Ommen SR, Will ML, Tajik AJ, Gersh BJ, Ackerman MJ (2004) J Am Coll Cardiol 44(9): 1903-10
    › Primary publication · 15519027 (PubMed)
  37. Comprehensive analysis of the beta-myosin heavy chain gene in 389 unrelated patients with hypertrophic cardiomyopathy. Van Driest SL, Jaeger MA, Ommen SR, Will ML, Gersh BJ, Tajik AJ, Ackerman MJ (2004) J Am Coll Cardiol 44(3): 602-10
    › Primary publication · 15358028 (PubMed)
  38. From malignant mutations to malignant domains: the continuing search for prognostic significance in the mutant genes causing hypertrophic cardiomyopathy. Van Driest SL, Maron BJ, Ackerman MJ (2004) Heart 90(1): 7-8
    › Primary publication · 14676227 (PubMed) · PMC1768027 (PubMed Central)
  39. Prevalence and spectrum of thin filament mutations in an outpatient referral population with hypertrophic cardiomyopathy. Van Driest SL, Ellsworth EG, Ommen SR, Tajik AJ, Gersh BJ, Ackerman MJ (2003) Circulation 108(4): 445-51
    › Primary publication · 12860912 (PubMed)
  40. Prevalence and severity of "benign" mutations in the beta-myosin heavy chain, cardiac troponin T, and alpha-tropomyosin genes in hypertrophic cardiomyopathy. Van Driest SL, Ackerman MJ, Ommen SR, Shakur R, Will ML, Nishimura RA, Tajik AJ, Gersh BJ (2002) Circulation 106(24): 3085-90
    › Primary publication · 12473556 (PubMed)
  41. A novel TPM1 mutation in a family with hypertrophic cardiomyopathy and sudden cardiac death in childhood. Van Driest SL, Will ML, Atkins DL, Ackerman MJ (2002) Am J Cardiol 90(10): 1123-7
    › Primary publication · 12423715 (PubMed)
  42. Prevalence and age-dependence of malignant mutations in the beta-myosin heavy chain and troponin T genes in hypertrophic cardiomyopathy: a comprehensive outpatient perspective. Ackerman MJ, VanDriest SL, Ommen SR, Will ML, Nishimura RA, Tajik AJ, Gersh BJ (2002) J Am Coll Cardiol 39(12): 2042-8
    › Primary publication · 12084606 (PubMed)