Tonia Rex
Last active: 11/18/2020


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The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Galantamine protects against synaptic, axonal, and vision deficits in experimental neurotrauma. Naguib S, Bernardo-Colón A, Cencer C, Gandra N, Rex TS (2020) Neurobiol Dis : 104695
    › Primary publication · 31778813 (PubMed) · PMC7769189 (PubMed Central)
  2. Progression and Pathology of Traumatic Optic Neuropathy From Repeated Primary Blast Exposure. Bernardo-Colón A, Vest V, Cooper ML, Naguib SA, Calkins DJ, Rex TS (2019) Front Neurosci : 719
    › Primary publication · 31354422 (PubMed) · PMC6637732 (PubMed Central)
  3. Phenotypes of primary retinal macroglia: Implications for purification and culture conditions. Backstrom JR, Sheng J, Fischer RA, Sappington RM, Rex TS (2019) Exp Eye Res : 85-92
    › Primary publication · 30902621 (PubMed) · PMC6504593 (PubMed Central)
  4. Rapid Repeat Exposure to Subthreshold Trauma Causes Synergistic Axonal Damage and Functional Deficits in the Visual Pathway in a Mouse Model. Vest V, Bernardo-Colón A, Watkins D, Kim B, Rex TS (2019) J Neurotrauma 36(10): 1646-1654
    › Primary publication · 30451083 (PubMed) · PMC6531903 (PubMed Central)
  5. Antioxidants prevent inflammation and preserve the optic projection and visual function in experimental neurotrauma. Bernardo-Colón A, Vest V, Clark A, Cooper ML, Calkins DJ, Harrison FE, Rex TS (2018) Cell Death Dis 9(11): 1097
    › Primary publication · 30367086 (PubMed) · PMC6203845 (PubMed Central)
  6. Erythropoietin Slows Photoreceptor Cell Death in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa. Rex TS, Kasmala L, Bond WS, de Lucas Cerrillo AM, Wynn K, Lewin AS (2016) PLoS One 11(6): e0157411
    › Primary publication · 27299810 (PubMed) · PMC4907422 (PubMed Central)
  7. Erythropoietin either Prevents or Exacerbates Retinal Damage from Eye Trauma Depending on Treatment Timing. Bricker-Anthony C, D'Surney L, Lunn B, Hines-Beard J, Jo M, Bernardo-Colon A, Rex TS (2017) Optom Vis Sci 94(1): 20-32
    › Primary publication · 27281679 (PubMed) · PMC5206811 (PubMed Central)
  8. Effects of Repeated Anesthesia Containing Urethane on Tumor Formation and Health Scores in Male C57BL/6J Mice. Rex TS, Boyd K, Apple T, Bricker-Anthony C, Vail K, Wallace J (2016) J Am Assoc Lab Anim Sci 55(3): 295-9
    › Primary publication · 27177562 (PubMed) · PMC4865690 (PubMed Central)
  9. Eye-Directed Overpressure Airwave-Induced Trauma Causes Lasting Damage to the Anterior and Posterior Globe: A Model for Testing Cell-Based Therapies. Bricker-Anthony C, Hines-Beard J, Rex TS (2016) J Ocul Pharmacol Ther 32(5): 286-95
    › Primary publication · 26982447 (PubMed) · PMC4904234 (PubMed Central)
  10. Virus-mediated EpoR76E gene therapy preserves vision in a glaucoma model by modulating neuroinflammation and decreasing oxidative stress. Hines-Beard J, Bond WS, Backstrom JR, Rex TS (2016) J Neuroinflammation : 39
    › Primary publication · 26876380 (PubMed) · PMC4753658 (PubMed Central)
  11. Virus-mediated EpoR76E Therapy Slows Optic Nerve Axonopathy in Experimental Glaucoma. Bond WS, Hines-Beard J, GoldenMerry YL, Davis M, Farooque A, Sappington RM, Calkins DJ, Rex TS (2016) Mol Ther 24(2): 230-239
    › Primary publication · 26502777 (PubMed) · PMC4817814 (PubMed Central)
  12. A Novel Closed-Head Model of Mild Traumatic Brain Injury Using Focal Primary Overpressure Blast to the Cranium in Mice. Guley NH, Rogers JT, Del Mar NA, Deng Y, Islam RM, D'Surney L, Ferrell J, Deng B, Hines-Beard J, Bu W, Ren H, Elberger AJ, Marchetta JG, Rex TS, Honig MG, Reiner A (2016) J Neurotrauma 33(4): 403-22
    › Primary publication · 26414413 (PubMed) · PMC4761824 (PubMed Central)
  13. Gene therapy to treat inherited and complex retinal degenerative diseases. Rex TS (2015) Mol Ther Methods Clin Dev : 15027
    › Primary publication · 26251841 (PubMed) · PMC4525775 (PubMed Central)
  14. Neurodegeneration and Vision Loss after Mild Blunt Trauma in the C57Bl/6 and DBA/2J Mouse. Bricker-Anthony C, Rex TS (2015) PLoS One 10(7): e0131921
    › Primary publication · 26148200 (PubMed) · PMC4493046 (PubMed Central)
  15. Elucidating the effects of primary blast on the eye. Rex TS, Reilly MA, Sponsel WE (2015) Clin Exp Ophthalmol 43(3): 197-9
    › Primary publication · 25923380 (PubMed) · PMC5461916 (PubMed Central)
  16. Safety and angiogenic effects of systemic gene delivery of a modified erythropoietin. de Lucas Cerrillo AM, Bond WS, Rex TS (2015) Gene Ther 22(5): 365-73
    › Primary publication · 25716531 (PubMed) · PMC4425572 (PubMed Central)
  17. Delayed vision loss and therapeutic intervention after blast injury. Rex TS (2014) Invest Ophthalmol Vis Sci 55(12): 8342
    › Primary publication · 25525189 (PubMed)
  18. Exacerbation of blast-induced ocular trauma by an immune response. Bricker-Anthony C, Hines-Beard J, D'Surney L, Rex TS (2014) J Neuroinflammation : 192
    › Primary publication · 25472427 (PubMed) · PMC4264554 (PubMed Central)
  19. Evidence That Erythropoietin Modulates Neuroinflammation through Differential Action on Neurons, Astrocytes, and Microglia. Bond WS, Rex TS (2014) Front Immunol : 523
    › Primary publication · 25374571 (PubMed) · PMC4205853 (PubMed Central)
  20. Molecular changes and vision loss in a mouse model of closed-globe blast trauma. Bricker-Anthony C, Hines-Beard J, Rex TS (2014) Invest Ophthalmol Vis Sci 55(8): 4853-62
    › Primary publication · 24994864 (PubMed) · PMC4123895 (PubMed Central)
  21. A novel closed-head model of mild traumatic brain injury caused by primary overpressure blast to the cranium produces sustained emotional deficits in mice. Heldt SA, Elberger AJ, Deng Y, Guley NH, Del Mar N, Rogers J, Choi GW, Ferrell J, Rex TS, Honig MG, Reiner A (2014) Front Neurol : 2
    › Primary publication · 24478749 (PubMed) · PMC3898331 (PubMed Central)
  22. Identification of a therapeutic dose of continuously delivered erythropoietin in the eye using an inducible promoter system. Hines-Beard J, Desai S, Haag R, Esumi N, D'Surney L, Parker S, Richardson C, Rex TS (2013) Curr Gene Ther 13(4): 275-81
    › Primary publication · 23773177 (PubMed) · PMC4032115 (PubMed Central)
  23. Innate immune network in the retina activated by optic nerve crush. Templeton JP, Freeman NE, Nickerson JM, Jablonski MM, Rex TS, Williams RW, Geisert EE (2013) Invest Ophthalmol Vis Sci 54(4): 2599-606
    › Primary publication · 23493296 (PubMed) · PMC3629889 (PubMed Central)
  24. A single intramuscular injection of rAAV-mediated mutant erythropoietin protects against MPTP-induced parkinsonism. Dhanushkodi A, Akano EO, Roguski EE, Xue Y, Rao SK, Matta SG, Rex TS, McDonald MP (2013) Genes Brain Behav 12(2): 224-33
    › Primary publication · 23190369 (PubMed) · PMC4360975 (PubMed Central)
  25. A mouse model of ocular blast injury that induces closed globe anterior and posterior pole damage. Hines-Beard J, Marchetta J, Gordon S, Chaum E, Geisert EE, Rex TS (2012) Exp Eye Res : 63-70
    › Primary publication · 22504073 (PubMed) · PMC3922065 (PubMed Central)
  26. Dose-dependent treatment of optic nerve crush by exogenous systemic mutant erythropoietin. Sullivan TA, Geisert EE, Templeton JP, Rex TS (2012) Exp Eye Res 96(1): 36-41
    › Primary publication · 22306016 (PubMed) · PMC3350094 (PubMed Central)
  27. Systemic adeno-associated virus-mediated gene therapy preserves retinal ganglion cells and visual function in DBA/2J glaucomatous mice. Sullivan TA, Geisert EE, Hines-Beard J, Rex TS (2011) Hum Gene Ther 22(10): 1191-200
    › Primary publication · 21542676 (PubMed) · PMC3205793 (PubMed Central)
  28. Systemic gene delivery protects the photoreceptors in the retinal degeneration slow mouse. Sullivan T, Kodali K, Rex TS (2011) Neurochem Res 36(4): 613-8
    › Primary publication · 20924671 (PubMed)
  29. Neuroprotection of photoreceptors by direct delivery of erythropoietin to the retina of the retinal degeneration slow mouse. Rex TS, Wong Y, Kodali K, Merry S (2009) Exp Eye Res 89(5): 735-40
    › Primary publication · 19591826 (PubMed) · PMC2757459 (PubMed Central)
  30. Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice. Allocca M, Doria M, Petrillo M, Colella P, Garcia-Hoyos M, Gibbs D, Kim SR, Maguire A, Rex TS, Di Vicino U, Cutillo L, Sparrow JR, Williams DS, Bennett J, Auricchio A (2008) J Clin Invest 118(5): 1955-64
    › Primary publication · 18414684 (PubMed) · PMC2298836 (PubMed Central)
  31. Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer. Bennicelli J, Wright JF, Komaromy A, Jacobs JB, Hauck B, Zelenaia O, Mingozzi F, Hui D, Chung D, Rex TS, Wei Z, Qu G, Zhou S, Zeiss C, Arruda VR, Acland GM, Dell'Osso LF, High KA, Maguire AM, Bennett J (2008) Mol Ther 16(3): 458-65
    › Primary publication · 18209734 (PubMed) · PMC2842085 (PubMed Central)
  32. Virus-mediated gene delivery to neuronal progenitors. Rex TS (2008) Adv Exp Med Biol : 147-53
    › Primary publication · 18188939 (PubMed)
  33. Rescue of sight by gene therapy - closer than it may appear. Rex TS (2007) Ophthalmic Genet 28(3): 127-33
    › Primary publication · 17896310 (PubMed)
  34. SIRT1 activation confers neuroprotection in experimental optic neuritis. Shindler KS, Ventura E, Rex TS, Elliott P, Rostami A (2007) Invest Ophthalmol Vis Sci 48(8): 3602-9
    › Primary publication · 17652729 (PubMed) · PMC1964753 (PubMed Central)
  35. The distribution, concentration, and toxicity of enhanced green fluorescent protein in retinal cells after genomic or somatic (virus-mediated) gene transfer. Rex TS, Peet JA, Surace EM, Calvert PD, Nikonov SS, Lyubarsky AL, Bendo E, Hughes T, Pugh EN, Bennett J (2005) Mol Vis : 1236-45
    › Primary publication · 16402024 (PubMed)
  36. Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress. Rex TS, Tsui I, Hahn P, Maguire AM, Duan D, Bennett J, Dunaief JL (2004) Hum Gene Ther 15(10): 960-7
    › Primary publication · 15585111 (PubMed) · PMC4118285 (PubMed Central)
  37. Effect of over-expression of pigment epithelium derived factor (PEDF) on developing retinal vasculature in the mouse. Wong WT, Rex TS, Auricchio A, Maguire AM, Chung D, Tang W, Bennett J (2004) Mol Vis : 837-44
    › Primary publication · 15547489 (PubMed)
  38. Systemic but not intraocular Epo gene transfer protects the retina from light-and genetic-induced degeneration. Rex TS, Allocca M, Domenici L, Surace EM, Maguire AM, Lyubarsky A, Cellerino A, Bennett J, Auricchio A (2004) Mol Ther 10(5): 855-61
    › Primary publication · 15509503 (PubMed)
  39. In utero gene therapy rescues vision in a murine model of congenital blindness. Dejneka NS, Surace EM, Aleman TS, Cideciyan AV, Lyubarsky A, Savchenko A, Redmond TM, Tang W, Wei Z, Rex TS, Glover E, Maguire AM, Pugh EN, Jacobson SG, Bennett J (2004) Mol Ther 9(2): 182-8
    › Primary publication · 14759802 (PubMed)
  40. Gene therapy and animal models for retinal disease. Dejneka NS, Rex TS, Bennett J (2003) Dev Ophthalmol : 188-98
    › Primary publication · 12876838 (PubMed)
  41. Delivery of adeno-associated virus vectors to the fetal retina: impact of viral capsid proteins on retinal neuronal progenitor transduction. Surace EM, Auricchio A, Reich SJ, Rex T, Glover E, Pineles S, Tang W, O'Connor E, Lyubarsky A, Savchenko A, Pugh EN, Maguire AM, Wilson JM, Bennett J (2003) J Virol 77(14): 7957-63
    › Primary publication · 12829835 (PubMed) · PMC161923 (PubMed Central)
  42. Differential expression of cone opsin mRNA levels following experimental retinal detachment and reattachment. Rex TS, Lewis GP, Geller SF, Fisher SK (2002) Mol Vis : 114-8
    › Primary publication · 11979236 (PubMed)
  43. A survey of molecular expression by photoreceptors after experimental retinal detachment. Rex TS, Fariss RN, Lewis GP, Linberg KA, Sokal I, Fisher SK (2002) Invest Ophthalmol Vis Sci 43(4): 1234-47
    › Primary publication · 11923271 (PubMed)
  44. Experimental retinal detachment: a paradigm for understanding the effects of induced photoreceptor degeneration. Fisher SK, Stone J, Rex TS, Linberg KA, Lewis GP (2001) Prog Brain Res : 679-98
    › Primary publication · 11420980 (PubMed)
  45. Distribution of S- and M-cones in normal and experimentally detached cat retina. Linberg KA, Lewis GP, Shaaw C, Rex TS, Fisher SK (2001) J Comp Neurol 430(3): 343-56
    › Primary publication · 11169472 (PubMed)
  46. The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective. Winkler BS, Orselli SM, Rex TS (1994) Free Radic Biol Med 17(4): 333-49
    › Primary publication · 8001837 (PubMed)