Fred Lamb
Last active: 3/26/2019


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The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Modulation of ClC-3 gating and proton/anion exchange by internal and external protons and the anion selectivity filter. Rohrbough J, Nguyen HN, Lamb FS (2018) J Physiol 596(17): 4091-4119
    › Primary publication · 29917234 (PubMed) · PMC6117567 (PubMed Central)
  2. Endothelial nitric oxide synthase modulates Toll-like receptor 4-mediated IL-6 production and permeability via nitric oxide-independent signaling. Stark RJ, Koch SR, Choi H, Mace EH, Dikalov SI, Sherwood ER, Lamb FS (2018) FASEB J 32(2): 945-956
    › Primary publication · 29061842 (PubMed) · PMC5888395 (PubMed Central)
  3. LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis. Choi H, Ettinger N, Rohrbough J, Dikalova A, Nguyen HN, Lamb FS (2016) Free Radic Biol Med : 413-423
    › Primary publication · 27838438 (PubMed) · PMC5206799 (PubMed Central)
  4. Potentiation and tolerance of toll-like receptor priming in human endothelial cells. Koch SR, Lamb FS, Hellman J, Sherwood ER, Stark RJ (2017) Transl Res : 53-67.e4
    › Primary publication · 27567430 (PubMed) · PMC5253081 (PubMed Central)
  5. Regulation of arterial reactivity by concurrent signaling through the E-prostanoid receptor 3 and angiotensin receptor 1. Kraemer MP, Choi H, Reese J, Lamb FS, Breyer RM (2016) Vascul Pharmacol : 47-54
    › Primary publication · 27260940 (PubMed) · PMC4976016 (PubMed Central)
  6. Endothelial cell tolerance to lipopolysaccharide challenge is induced by monophosphoryl lipid A. Stark RJ, Choi H, Koch SR, Fensterheim BA, Lamb FS, Sherwood ER (2016) Clin Sci (Lond) 130(6): 451-61
    › Primary publication · 26669797 (PubMed) · PMC4744094 (PubMed Central)
  7. Standardizing ICU management of pediatric traumatic brain injury is associated with improved outcomes at discharge. O'Lynnger TM, Shannon CN, Le TM, Greeno A, Chung D, Lamb FS, Wellons JC (2016) J Neurosurg Pediatr 17(1): 19-26
    › Primary publication · 26451717 (PubMed)
  8. c-Jun N-terminal kinase attenuates TNFα signaling by reducing Nox1-dependent endosomal ROS production in vascular smooth muscle cells. Choi H, Dikalova A, Stark RJ, Lamb FS (2015) Free Radic Biol Med : 219-27
    › Primary publication · 26001727 (PubMed)
  9. Localising oxidant "stress" in the antiphospholipid syndrome. Lamb FS (2015) Thromb Haemost 113(5): 915
    › Primary publication · 25832773 (PubMed)
  10. Monophosphoryl lipid A inhibits the cytokine response of endothelial cells challenged with LPS. Stark R, Choi H, Koch S, Lamb F, Sherwood E (2015) Innate Immun 21(6): 565-74
    › Primary publication · 25540284 (PubMed) · PMC4480205 (PubMed Central)
  11. Pediatric posterior reversible encephalopathy syndrome presenting with isolated cerebellar edema and obstructive hydrocephalus. Ettinger N, Pearson M, Lamb FS, Wellons JC (2014) J Neurosurg Pediatr 14(4): 344-7
    › Primary publication · 25062302 (PubMed) · PMC4332559 (PubMed Central)
  12. Inhibition of endocytosis exacerbates TNF-α-induced endothelial dysfunction via enhanced JNK and p38 activation. Choi H, Nguyen HN, Lamb FS (2014) Am J Physiol Heart Circ Physiol 306(8): H1154-63
    › Primary publication · 24561862 (PubMed)
  13. Placental HSD2 Expression and Activity Is Unaffected by Maternal Protein Consumption or Gender in C57BL/6 Mice. Garbrecht MR, Lamb FS (2013) ISRN Endocrinol : 867938
    › Primary publication · 23781346 (PubMed) · PMC3679810 (PubMed Central)
  14. Spontaneous Rhythmic Contractions (Vasomotion) of the Isolated, Pressurized Ductus Arteriosus of Preterm, but Not Term, Fetal Mice. Vucovich M, Ehinger N, Poole SD, Lamb FS, Reese J (2012) EJ Neonatol Res 2(1): 13-24
    › Primary publication · 23710420 (PubMed) · PMC3661283 (PubMed Central)
  15. Residual lesions in postoperative pediatric cardiac surgery patients receiving extracorporeal membrane oxygenation support. Agarwal HS, Hardison DC, Saville BR, Donahue BS, Lamb FS, Bichell DP, Harris ZL (2014) J Thorac Cardiovasc Surg 147(1): 434-41
    › Primary publication · 23597724 (PubMed)
  16. Functional regulation of ClC-3 in the migration of vascular smooth muscle cells. Ganapathi SB, Wei SG, Zaremba A, Lamb FS, Shears SB (2013) Hypertension 61(1): 174-9
    › Primary publication · 23150504 (PubMed) · PMC3521842 (PubMed Central)
  17. Impact of maternal dexamethasone on coronary PGE(2) production and prostaglandin-dependent coronary reactivity. Roghair RD, Volk KA, Lamb FS, Segar JL (2012) Am J Physiol Regul Integr Comp Physiol 303(5): R513-9
    › Primary publication · 22832534 (PubMed) · PMC3468415 (PubMed Central)
  18. Endotoxin priming of neutrophils requires endocytosis and NADPH oxidase-dependent endosomal reactive oxygen species. Lamb FS, Hook JS, Hilkin BM, Huber JN, Volk AP, Moreland JG (2012) J Biol Chem 287(15): 12395-404
    › Primary publication · 22235113 (PubMed) · PMC3320989 (PubMed Central)
  19. Maternal antioxidant blocks programmed cardiovascular and behavioural stress responses in adult mice. Roghair RD, Wemmie JA, Volk KA, Scholz TD, Lamb FS, Segar JL (2011) Clin Sci (Lond) 121(10): 427-36
    › Primary publication · 21615331 (PubMed) · PMC3677964 (PubMed Central)
  20. A critical role for chloride channel-3 (CIC-3) in smooth muscle cell activation and neointima formation. Chu X, Filali M, Stanic B, Takapoo M, Sheehan A, Bhalla R, Lamb FS, Miller FJ (2011) Arterioscler Thromb Vasc Biol 31(2): 345-51
    › Primary publication · 21071705 (PubMed) · PMC3025755 (PubMed Central)
  21. Activation of swelling-activated chloride current by tumor necrosis factor-alpha requires ClC-3-dependent endosomal reactive oxygen production. Matsuda JJ, Filali MS, Moreland JG, Miller FJ, Lamb FS (2010) J Biol Chem 285(30): 22864-73
    › Primary publication · 20479003 (PubMed) · PMC2906278 (PubMed Central)
  22. Coronary endothelial function and vascular smooth muscle proliferation are programmed by early-gestation dexamethasone exposure in sheep. Volk KA, Roghair RD, Jung F, Scholz TD, Lamb FS, Segar JL (2010) Am J Physiol Regul Integr Comp Physiol 298(6): R1607-14
    › Primary publication · 20335378 (PubMed) · PMC2886704 (PubMed Central)
  23. The ClC-3 Cl-/H+ antiporter becomes uncoupled at low extracellular pH. Matsuda JJ, Filali MS, Collins MM, Volk KA, Lamb FS (2010) J Biol Chem 285(4): 2569-79
    › Primary publication · 19926787 (PubMed) · PMC2807314 (PubMed Central)
  24. A differential role for endocytosis in receptor-mediated activation of Nox1. Miller FJ, Chu X, Stanic B, Tian X, Sharma RV, Davisson RL, Lamb FS (2010) Antioxid Redox Signal 12(5): 583-93
    › Primary publication · 19737091 (PubMed) · PMC2861543 (PubMed Central)
  25. Electrophysiology of reactive oxygen production in signaling endosomes. Lamb FS, Moreland JG, Miller FJ (2009) Antioxid Redox Signal 11(6): 1335-47
    › Primary publication · 19207039 (PubMed) · PMC2872256 (PubMed Central)
  26. Vascular nitric oxide and superoxide anion contribute to sex-specific programmed cardiovascular physiology in mice. Roghair RD, Segar JL, Volk KA, Chapleau MW, Dallas LM, Sorenson AR, Scholz TD, Lamb FS (2009) Am J Physiol Regul Integr Comp Physiol 296(3): R651-62
    › Primary publication · 19144750 (PubMed) · PMC2665850 (PubMed Central)
  27. Fetal programming alters reactive oxygen species production in sheep cardiac mitochondria. von Bergen NH, Koppenhafer SL, Spitz DR, Volk KA, Patel SS, Roghair RD, Lamb FS, Segar JL, Scholz TD (2009) Clin Sci (Lond) 116(8): 659-68
    › Primary publication · 19032144 (PubMed) · PMC3677965 (PubMed Central)
  28. ClC-3 and IClswell are required for normal neutrophil chemotaxis and shape change. Volk AP, Heise CK, Hougen JL, Artman CM, Volk KA, Wessels D, Soll DR, Nauseef WM, Lamb FS, Moreland JG (2008) J Biol Chem 283(49): 34315-26
    › Primary publication · 18840613 (PubMed) · PMC2590705 (PubMed Central)
  29. Coronary constriction to angiotensin II is enhanced by endothelial superoxide production in sheep programmed by dexamethasone. Roghair RD, Miller FJ, Scholz TD, Lamb FS, Segar JL (2008) Pediatr Res 63(4): 370-4
    › Primary publication · 18356741 (PubMed) · PMC3663587 (PubMed Central)
  30. Overexpression of CLC-3 in HEK293T cells yields novel currents that are pH dependent. Matsuda JJ, Filali MS, Volk KA, Collins MM, Moreland JG, Lamb FS (2008) Am J Physiol Cell Physiol 294(1): C251-62
    › Primary publication · 17977943 (PubMed)
  31. Surfactant-associated protein A provides critical immunoprotection in neonatal mice. George CL, Goss KL, Meyerholz DK, Lamb FS, Snyder JM (2008) Infect Immun 76(1): 380-90
    › Primary publication · 17967856 (PubMed) · PMC2223658 (PubMed Central)
  32. Endotoxin priming of neutrophils requires NADPH oxidase-generated oxidants and is regulated by the anion transporter ClC-3. Moreland JG, Davis AP, Matsuda JJ, Hook JS, Bailey G, Nauseef WM, Lamb FS (2007) J Biol Chem 282(47): 33958-67
    › Primary publication · 17908687 (PubMed)
  33. Murine aortic reactivity is programmed equally by maternal low protein diet or late gestation dexamethasone. Roghair RD, Segar JL, Kilpatrick RA, Segar EM, Scholz TD, Lamb FS (2007) J Matern Fetal Neonatal Med 20(11): 833-41
    › Primary publication · 17853187 (PubMed)