Joyce Cheung-Flynn
Last active: 5/12/2020


None provided


The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Cell-free hemoglobin increases inflammation, lung apoptosis, and microvascular permeability in murine polymicrobial sepsis. Meegan JE, Shaver CM, Putz ND, Jesse JJ, Landstreet SR, Lee HNR, Sidorova TN, McNeil JB, Wynn JL, Cheung-Flynn J, Komalavilas P, Brophy CM, Ware LB, Bastarache JA (2020) PLoS One 15(2): e0228727
    › Primary publication · 32012200 (PubMed) · PMC6996826 (PubMed Central)
  2. An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles. Evans BC, Fletcher RB, Kilchrist KV, Dailing EA, Mukalel AJ, Colazo JM, Oliver M, Cheung-Flynn J, Brophy CM, Tierney JW, Isenberg JS, Hankenson KD, Ghimire K, Lander C, Gersbach CA, Duvall CL (2019) Nat Commun 10(1): 5012
    › Primary publication · 31676764 (PubMed) · PMC6825215 (PubMed Central)
  3. Normal Saline solutions cause endothelial dysfunction through loss of membrane integrity, ATP release, and inflammatory responses mediated by P2X7R/p38 MAPK/MK2 signaling pathways. Cheung-Flynn J, Alvis BD, Hocking KM, Guth CM, Luo W, McCallister R, Chadalavada K, Polcz M, Komalavilas P, Brophy CM (2019) PLoS One 14(8): e0220893
    › Primary publication · 31412063 (PubMed) · PMC6693757 (PubMed Central)
  4. Nanotechnology Enabled Modulation of Signaling Pathways Affects Physiologic Responses in Intact Vascular Tissue. Hocking KM, Evans BC, Komalavilas P, Cheung-Flynn J, Duvall CL, Brophy CM (2019) Tissue Eng Part A 25(5-6): 416-426
    › Primary publication · 30132374 (PubMed) · PMC6450456 (PubMed Central)
  5. Vascular surgical stretch injury leads to activation of P2X7 receptors and impaired endothelial function. Komalavilas P, Luo W, Guth CM, Jolayemi O, Bartelson RI, Cheung-Flynn J, Brophy CM (2017) PLoS One 12(11): e0188069
    › Primary publication · 29136654 (PubMed) · PMC5685620 (PubMed Central)
  6. Limiting Injury During Saphenous Vein Graft Preparation For Coronary Arterial Bypass Prevents Metabolic Decompensation. Cheung-Flynn J, Song J, Voskresensky I, Wise ES, Liu Y, Xiong Y, Eagle SS, Brophy CM, Flynn CR (2017) Sci Rep 7(1): 14179
    › Primary publication · 29079734 (PubMed) · PMC5660200 (PubMed Central)
  7. Heparin-functionalized polymer graft surface eluting MK2 inhibitory peptide to improve hemocompatibility and anti-neointimal activity. Lee Y, Le Thi P, Seon GM, Ryu SB, Brophy CM, Kim Y, Park JC, Park KD, Cheung-Flynn J, Sung HJ (2017) J Control Release : 321-330
    › Primary publication · 28987880 (PubMed) · PMC5723561 (PubMed Central)
  8. P2X7R antagonism after subfailure overstretch injury of blood vessels reverses vasomotor dysfunction and prevents apoptosis. Luo W, Feldman D, McCallister R, Brophy C, Cheung-Flynn J (2017) Purinergic Signal 13(4): 579-590
    › Primary publication · 28905300 (PubMed) · PMC5714848 (PubMed Central)
  9. Unregulated saphenous vein graft distension decreases tissue viscoelasticity. Wise ES, Hocking KM, Evans BC, Duvall CL, Cheung-Flynn J, Brophy CM (2017) Perfusion 32(6): 489-494
    › Primary publication · 28820033 (PubMed) · PMC5967241 (PubMed Central)
  10. Adenosine triphosphate as a molecular mediator of the vascular response to injury. Guth CM, Luo W, Jolayemi O, Chadalavada KS, Komalavilas P, Cheung-Flynn J, Brophy CM (2017) J Surg Res : 80-86
    › Primary publication · 28807217 (PubMed) · PMC5962343 (PubMed Central)
  11. Calcification of Human Saphenous Vein Associated with Endothelial Dysfunction: A Pilot Histopathophysiological and Demographical Study. Pedigo SL, Guth CM, Hocking KM, Banathy A, Li FD, Cheung-Flynn J, Brophy CM, Guzman RJ, Komalavilas P (2017) Front Surg : 6
    › Primary publication · 28232909 (PubMed) · PMC5298955 (PubMed Central)
  12. Use of Brilliant Blue FCF during vein graft preparation inhibits intimal hyperplasia. Osgood MJ, Sexton K, Voskresensky I, Hocking K, Song J, Komalavilas P, Brophy C, Cheung-Flynn J (2016) J Vasc Surg 64(2): 471-478
    › Primary publication · 27763268 (PubMed) · PMC5480606 (PubMed Central)
  13. Subfailure Overstretch Injury Leads to Reversible Functional Impairment and Purinergic P2X7 Receptor Activation in Intact Vascular Tissue. Luo W, Guth CM, Jolayemi O, Duvall CL, Brophy CM, Cheung-Flynn J (2016) Front Bioeng Biotechnol : 75
    › Primary publication · 27747211 (PubMed) · PMC5040722 (PubMed Central)
  14. Biomaterial-Based Approaches to Address Vein Graft and Hemodialysis Access Failures. Boire TC, Balikov DA, Lee Y, Guth CM, Cheung-Flynn J, Sung HJ (2016) Macromol Rapid Commun 37(23): 1860-1880
    › Primary publication · 27673474 (PubMed) · PMC5156561 (PubMed Central)
  15. Standard Surgical Skin Markers Should Be Avoided for Intraoperative Vein Graft Marking during Cardiac and Peripheral Bypass Operations. Wise ES, Cheung-Flynn J, Brophy CM (2016) Front Surg : 36
    › Primary publication · 27379243 (PubMed) · PMC4913101 (PubMed Central)
  16. Traditional graft preparation decreases physiologic responses, diminishes viscoelasticity, and reduces cellular viability of the conduit: A porcine saphenous vein model. Wise ES, Hocking KM, Luo W, Feldman DL, Song J, Komalavilas P, Cheung-Flynn J, Brophy CM (2016) Vasc Med 21(5): 413-421
    › Primary publication · 27216870 (PubMed) · PMC5115945 (PubMed Central)
  17. Papaverine Prevents Vasospasm by Regulation of Myosin Light Chain Phosphorylation and Actin Polymerization in Human Saphenous Vein. Hocking KM, Putumbaka G, Wise ES, Cheung-Flynn J, Brophy CM, Komalavilas P (2016) PLoS One 11(5): e0154460
    › Primary publication · 27136356 (PubMed) · PMC4852981 (PubMed Central)
  18. Heat Shock-Related Protein 20 Peptide Decreases Human Airway Constriction Downstream of β2-Adrenergic Receptor. Banathy A, Cheung-Flynn J, Goleniewska K, Boyd KL, Newcomb DC, Peebles RS, Komalavilas P (2016) Am J Respir Cell Mol Biol 55(2): 225-33
    › Primary publication · 26909644 (PubMed) · PMC4979360 (PubMed Central)
  19. Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery. Flynn CR, Albaugh VL, Cai S, Cheung-Flynn J, Williams PE, Brucker RM, Bordenstein SR, Guo Y, Wasserman DH, Abumrad NN (2015) Nat Commun : 7715
    › Primary publication · 26197299 (PubMed) · PMC4518285 (PubMed Central)
  20. An Optimized Preparation Technique for Saphenous Vein Graft. Wise ES, Hocking KM, Feldman D, Komalavilas P, Cheung-Flynn J, Brophy CM (2015) Am Surg 81(7): E274-6
    › Primary publication · 26140874 (PubMed) · PMC4635024 (PubMed Central)
  21. Preservation solution impacts physiologic function and cellular viability of human saphenous vein graft. Wise ES, Hocking KM, Eagle S, Absi T, Komalavilas P, Cheung-Flynn J, Brophy CM (2015) Surgery 158(2): 537-46
    › Primary publication · 26003912 (PubMed) · PMC4492846 (PubMed Central)
  22. Brilliant blue FCF is a nontoxic dye for saphenous vein graft marking that abrogates response to injury. Hocking KM, Luo W, Li FD, Komalavilas P, Brophy C, Cheung-Flynn J (2016) J Vasc Surg 64(1): 210-8
    › Primary publication · 25704409 (PubMed) · PMC4544660 (PubMed Central)
  23. Brilliant blue FCF as an alternative dye for saphenous vein graft marking: effect on conduit function. Voskresensky IV, Wise ES, Hocking KM, Li FD, Osgood MJ, Komalavilas P, Brophy C, Cheung-Flynn J (2014) JAMA Surg 149(11): 1176-81
    › Primary publication · 25251505 (PubMed) · PMC4237645 (PubMed Central)
  24. Pressure control during preparation of saphenous veins. Li FD, Eagle S, Brophy C, Hocking KM, Osgood M, Komalavilas P, Cheung-Flynn J (2014) JAMA Surg 149(7): 655-62
    › Primary publication · 24759942 (PubMed) · PMC4102634 (PubMed Central)
  25. Role of the renin-angiotensin system in the pathogenesis of intimal hyperplasia: therapeutic potential for prevention of vein graft failure? Osgood MJ, Harrison DG, Sexton KW, Hocking KM, Voskresensky IV, Komalavilas P, Cheung-Flynn J, Guzman RJ, Brophy CM (2012) Ann Vasc Surg 26(8): 1130-44
    › Primary publication · 22445245 (PubMed) · PMC4189806 (PubMed Central)
  26. Surgical skin markers impair human saphenous vein graft smooth muscle and endothelial function. Eagle S, Brophy CM, Komalavilas P, Hocking K, Putumbaka G, Osgood M, Sexton K, Leacche M, Cheung-Flynn J (2011) Am Surg 77(7): 922-8
    › Primary publication · 21944360 (PubMed) · PMC3957273 (PubMed Central)
  27. Functional specificity of co-chaperone interactions with Hsp90 client proteins. Riggs DL, Cox MB, Cheung-Flynn J, Prapapanich V, Carrigan PE, Smith DF (2004) Crit Rev Biochem Mol Biol 39(5-6): 279-95
    › Primary publication · 15763706 (PubMed)