Carissa Cascio
Last active: 3/14/2018


Dr. Cascio's research program is focused on sensory and repetitive behaviors in autism spectrum disorders (ASD). The lab uses direct observational assessment of sensation, perception, and behavior. These approaches are combined with neuroimaging and neurophysiological approaches such as functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), and event-related potentials (ERP). The goal of the lab is to better understand how basic sensory and limbic neural systems contribute to the complex array of social and communication impairments in ASD. Current projects include: 1) an fMRI study of limbic/reward system activation in response to circumscribed interests in ASD, 2) a DTI study of sensory thalamocortical pathways as they relate to sensory hyper- and hyporesponsiveness in ASD, 3) an ERP study of steady state potentials and sensory processing in a high-risk group of infant siblings of children with ASD. Pilot and methodological projects include: 1) an ERP study of affective touch in children with ASD, 2) development of behavioral approaches for pediatric neuroimaging, including a biofeedback motion training program for use in a mock scanner environment.


The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Associations Between Interoceptive Cognition and Age in Autism Spectrum Disorder and Typical Development. Mash LE, Schauder KB, Cochran C, Park S, Cascio CJ (2017) J Cogn Educ Psychol 16(1): 23-37
    › Primary publication · 29152038 (PubMed) · PMC5693363 (PubMed Central)
  2. Disrupted integration of exteroceptive and interoceptive signaling in autism spectrum disorder. Noel JP, Lytle M, Cascio C, Wallace MT (2018) Autism Res 11(1): 194-205
    › Primary publication · 29030901 (PubMed) · PMC5773377 (PubMed Central)
  3. Developmental sequelae and neurophysiologic substrates of sensory seeking in infant siblings of children with autism spectrum disorder. Damiano-Goodwin CR, Woynaroski TG, Simon DM, Ibañez LV, Murias M, Kirby A, Newsom CR, Wallace MT, Stone WL, Cascio CJ (2018) Dev Cogn Neurosci : 41-53
    › Primary publication · 28889988 (PubMed) · PMC5812859 (PubMed Central)
  4. Intrainsular connectivity and somatosensory responsiveness in young children with ASD. Failla MD, Peters BR, Karbasforoushan H, Foss-Feig JH, Schauder KB, Heflin BH, Cascio CJ (2017) Mol Autism : 25
    › Primary publication · 28630661 (PubMed) · PMC5470196 (PubMed Central)
  5. Neural Correlates of Sensory Hyporesponsiveness in Toddlers at High Risk for Autism Spectrum Disorder. Simon DM, Damiano CR, Woynaroski TG, Ibañez LV, Murias M, Stone WL, Wallace MT, Cascio CJ (2017) J Autism Dev Disord 47(9): 2710-2722
    › Primary publication · 28597185 (PubMed) · PMC5880549 (PubMed Central)
  6. Thalamocortical dysconnectivity in autism spectrum disorder: An analysis of the Autism Brain Imaging Data Exchange. Woodward ND, Giraldo-Chica M, Rogers B, Cascio CJ (2017) Biol Psychiatry Cogn Neurosci Neuroimaging 2(1): 76-84
    › Primary publication · 28584881 (PubMed) · PMC5455796 (PubMed Central)
  7. Initially intact neural responses to pain in autism are diminished during sustained pain. Failla MD, Moana-Filho EJ, Essick GK, Baranek GT, Rogers BP, Cascio CJ (2018) Autism 22(6): 669-683
    › Primary publication · 28513186 (PubMed) · PMC6352721 (PubMed Central)
  8. The spatial self in schizophrenia and autism spectrum disorder. Noel JP, Cascio CJ, Wallace MT, Park S (2017) Schizophr Res : 8-12
    › Primary publication · 27650196 (PubMed) · PMC5219859 (PubMed Central)
  9. Toward an interdisciplinary approach to understanding sensory function in autism spectrum disorder. Cascio CJ, Woynaroski T, Baranek GT, Wallace MT (2016) Autism Res 9(9): 920-5
    › Primary publication · 27090878 (PubMed) · PMC5564205 (PubMed Central)
  10. A functional neuroimaging study of fusiform response to restricted interests in children and adolescents with autism spectrum disorder. Foss-Feig JH, McGugin RW, Gauthier I, Mash LE, Ventola P, Cascio CJ (2016) J Neurodev Disord : 15
    › Primary publication · 27081401 (PubMed) · PMC4831124 (PubMed Central)
  11. Brain structure in autism: a voxel-based morphometry analysis of the Autism Brain Imaging Database Exchange (ABIDE). Riddle K, Cascio CJ, Woodward ND (2017) Brain Imaging Behav 11(2): 541-551
    › Primary publication · 26941174 (PubMed) · PMC5010794 (PubMed Central)
  12. Resting-State Functional Connectivity in Psychiatric Disorders. Woodward ND, Cascio CJ (2015) JAMA Psychiatry 72(8): 743-4
    › Primary publication · 26061674 (PubMed) · PMC4693599 (PubMed Central)
  13. Somatosensory Event-Related Potentials and Association with Tactile Behavioral Responsiveness Patterns in Children with ASD. Cascio CJ, Gu C, Schauder KB, Key AP, Yoder P (2015) Brain Topogr 28(6): 895-903
    › Primary publication · 26016951 (PubMed) · PMC4601930 (PubMed Central)
  14. Genetic Variation in Serotonin Transporter Modulates Tactile Hyperresponsiveness in ASD. Schauder KB, Muller CL, Veenstra-VanderWeele J, Cascio CJ (2015) Res Autism Spectr Disord : 93-100
    › Primary publication · 25558276 (PubMed) · PMC4281265 (PubMed Central)
  15. Nonverbal patient with autism spectrum disorder and obstructive sleep apnea: use of desensitization to acclimatize to a dental appliance. Fetner M, Cascio CJ, Essick G (2014) Pediatr Dent 36(7): 499-501
    › Primary publication · 25514080 (PubMed)
  16. Interoceptive ability and body awareness in autism spectrum disorder. Schauder KB, Mash LE, Bryant LK, Cascio CJ (2015) J Exp Child Psychol : 193-200
    › Primary publication · 25498876 (PubMed) · PMC4303499 (PubMed Central)
  17. White matter correlates of sensory processing in autism spectrum disorders. Pryweller JR, Schauder KB, Anderson AW, Heacock JL, Foss-Feig JH, Newsom CR, Loring WA, Cascio CJ (2014) Neuroimage Clin : 379-87
    › Primary publication · 25379451 (PubMed) · PMC4218938 (PubMed Central)
  18. Affective neural response to restricted interests in autism spectrum disorders. Cascio CJ, Foss-Feig JH, Heacock J, Schauder KB, Loring WA, Rogers BP, Pryweller JR, Newsom CR, Cockhren J, Cao A, Bolton S (2014) J Child Psychol Psychiatry 55(2): 162-71
    › Primary publication · 24117668 (PubMed) · PMC3947089 (PubMed Central)
  19. Self-reported Pleasantness Ratings and Examiner-Coded Defensiveness in Response to Touch in Children with ASD: Effects of Stimulus Material and Bodily Location. Cascio CJ, Lorenzi J, Baranek GT (2016) J Autism Dev Disord 46(5): 1528-37
    › Primary publication · 24091471 (PubMed) · PMC3976859 (PubMed Central)
  20. A substantial and unexpected enhancement of motion perception in autism. Foss-Feig JH, Tadin D, Schauder KB, Cascio CJ (2013) J Neurosci 33(19): 8243-9
    › Primary publication · 23658163 (PubMed) · PMC3726259 (PubMed Central)
  21. Fractional anisotropy distributions in 2- to 6-year-old children with autism. Cascio C, Gribbin M, Gouttard S, Smith RG, Jomier M, Field S, Graves M, Hazlett HC, Muller K, Gerig G, Piven J (2013) J Intellect Disabil Res 57(11): 1037-49
    › Primary publication · 22998325 (PubMed) · PMC3606640 (PubMed Central)
  22. Response of neural reward regions to food cues in autism spectrum disorders. Cascio CJ, Foss-Feig JH, Heacock JL, Newsom CR, Cowan RL, Benningfield MM, Rogers BP, Cao A (2012) J Neurodev Disord 4(1): 9
    › Primary publication · 22958533 (PubMed) · PMC3436657 (PubMed Central)
  23. Perceptual and neural response to affective tactile texture stimulation in adults with autism spectrum disorders. Cascio CJ, Moana-Filho EJ, Guest S, Nebel MB, Weisner J, Baranek GT, Essick GK (2012) Autism Res 5(4): 231-44
    › Primary publication · 22447729 (PubMed) · PMC3517930 (PubMed Central)
  24. The rubber hand illusion in children with autism spectrum disorders: delayed influence of combined tactile and visual input on proprioception. Cascio CJ, Foss-Feig JH, Burnette CP, Heacock JL, Cosby AA (2012) Autism 16(4): 406-19
    › Primary publication · 22399451 (PubMed) · PMC3529180 (PubMed Central)
  25. Somatosensory processing in neurodevelopmental disorders. Cascio CJ (2010) J Neurodev Disord 2(2): 62-9
    › Primary publication · 22127855 (PubMed) · PMC3164038 (PubMed Central)
    › Primary publication · 22059092 (PubMed) · PMC3207504 (PubMed Central)
  27. Human Ecstasy use is associated with increased cortical excitability: an fMRI study. Bauernfeind AL, Dietrich MS, Blackford JU, Charboneau EJ, Lillevig JG, Cannistraci CJ, Woodward ND, Cao A, Watkins T, Di Iorio CR, Cascio C, Salomon RM, Cowan RL (2011) Neuropsychopharmacology 36(6): 1127-41
    › Primary publication · 21326196 (PubMed) · PMC3079831 (PubMed Central)
  28. Altered auditory and multisensory temporal processing in autism spectrum disorders. Kwakye LD, Foss-Feig JH, Cascio CJ, Stone WL, Wallace MT (2011) Front Integr Neurosci : 129
    › Primary publication · 21258617 (PubMed) · PMC3024004 (PubMed Central)
  29. An extended multisensory temporal binding window in autism spectrum disorders. Foss-Feig JH, Kwakye LD, Cascio CJ, Burnette CP, Kadivar H, Stone WL, Wallace MT (2010) Exp Brain Res 203(2): 381-9
    › Primary publication · 20390256 (PubMed) · PMC2871100 (PubMed Central)