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allosteric modulators Allosteric Regulation Allosteric Site Animals Binding Sites Body Size Bone and Bones Calcium Cell Line Cell Line, Tumor CHO Cells Cricetinae Cricetulus Cyclic AMP Exenatide Female Genotype GLP-1 Glucose High-Throughput Screening Assays Humans Insulin islet Liraglutide Mice Mice, Knockout Mice, Transgenic Osteogenesis Peptides pharmacokinetics Phenotype Receptor, Insulin Recombinant Proteins Signal Transduction