Leo Cheng
Last active: 4/26/2016

Profile

None provided

Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Diabetic gastroparesis alters the biomagnetic signature of the gastric slow wave. Bradshaw LA, Cheng LK, Chung E, Obioha CB, Erickson JC, Gorman BL, Somarajan S, Richards WO (2016) Neurogastroenterol Motil 28(6): 837-48
    › Primary publication · 26839980 (PubMed) · PMC4877247 (PubMed Central)
  2. Restoration of normal colonic motor patterns and meal responses after distal colorectal resection. Vather R, O'Grady G, Arkwright JW, Rowbotham DS, Cheng LK, Dinning PG, Bissett IP (2016) Br J Surg 103(4): 451-61
    › Primary publication · 26780492 (PubMed)
  3. Tissue specific simulations of interstitial cells of cajal networks using unstructured meshes. Sathar S, Trew ML, Cheng LK (2015) Conf Proc IEEE Eng Med Biol Soc : 8062-5
    › Primary publication · 26738164 (PubMed) · PMC4966885 (PubMed Central)
  4. A system for automated quantification of cutaneous electrogastrograms. Paskaranandavadivel N, Bull SH, Parsell D, Cheng LK, Abell TL (2015) Conf Proc IEEE Eng Med Biol Soc : 6098-101
    › Primary publication · 26737683 (PubMed)
  5. Detection of the Recovery Phase of in vivo gastric slow wave recordings. Paskaranandavadivel N, Pan X, Du P, O'Grady G, Cheng LK (2015) Conf Proc IEEE Eng Med Biol Soc : 6094-7
    › Primary publication · 26737682 (PubMed) · PMC4938633 (PubMed Central)
  6. Extending the automated gastrointestinal analysis pipeline: Removal of invalid slow wave marks in gastric serosal recordings. Paskaranandavadivel N, Du P, Erickson J, O'Grady G, Cheng LK (2015) Conf Proc IEEE Eng Med Biol Soc : 1938-41
    › Primary publication · 26736663 (PubMed) · PMC4958377 (PubMed Central)
  7. A comparison of solver performance for complex gastric electrophysiology models. Sathar S, Cheng LK, Trew ML (2015) Conf Proc IEEE Eng Med Biol Soc : 1452-5
    › Primary publication · 26736543 (PubMed) · PMC4966904 (PubMed Central)
  8. Determining the efficient inter-electrode distance for high-resolution mapping using a mathematical model of human gastric dysrhythmias. Putney J, O'Grady G, Angeli TR, Paskaranandavadivel N, Cheng LK, Erickson JC, Peng Du (2015) Conf Proc IEEE Eng Med Biol Soc : 1448-51
    › Primary publication · 26736542 (PubMed)
  9. The virtual intestine: in silico modeling of small intestinal electrophysiology and motility and the applications. Du P, Paskaranandavadivel N, Angeli TR, Cheng LK, O'Grady G (2016) Wiley Interdiscip Rev Syst Biol Med 8(1): 69-85
    › Primary publication · 26562482 (PubMed) · PMC5097873 (PubMed Central)
  10. Measuring Gastrointestinal Electrical Activity With Extracellular Electrodes. Grady GO, Angeli TR, Du P, Cheng LK (2015) J Neurogastroenterol Motil 21(4): 623-4
    › Primary publication · 26351249 (PubMed) · PMC4622148 (PubMed Central)
  11. The impact of surgical excisions on human gastric slow wave conduction, defined by high-resolution electrical mapping and in silico modeling. Du P, Hameed A, Angeli TR, Lahr C, Abell TL, Cheng LK, O'Grady G (2015) Neurogastroenterol Motil 27(10): 1409-22
    › Primary publication · 26251163 (PubMed) · PMC4598186 (PubMed Central)
  12. A Multiscale Tridomain Model for Simulating Bioelectric Gastric Pacing. Sathar S, Trew ML, OGrady G, Cheng LK (2015) IEEE Trans Biomed Eng 62(11): 2685-92
    › Primary publication · 26080372 (PubMed) · PMC4655104 (PubMed Central)
  13. Noninvasive biomagnetic detection of intestinal slow wave dysrhythmias in chronic mesenteric ischemia. Somarajan S, Muszynski ND, Cheng LK, Bradshaw LA, Naslund TC, Richards WO (2015) Am J Physiol Gastrointest Liver Physiol 309(1): G52-8
    › Primary publication · 25930082 (PubMed) · PMC4491509 (PubMed Central)
  14. Loss of Interstitial Cells of Cajal and Patterns of Gastric Dysrhythmia in Patients With Chronic Unexplained Nausea and Vomiting. Angeli TR, Cheng LK, Du P, Wang TH, Bernard CE, Vannucchi MG, Faussone-Pellegrini MS, Lahr C, Vather R, Windsor JA, Farrugia G, Abell TL, O'Grady G (2015) Gastroenterology 149(1): 56-66.e5
    › Primary publication · 25863217 (PubMed) · PMC4617790 (PubMed Central)
  15. Concerning the validity of gastrointestinal extracellular recordings. O'Grady G, Angeli T, Du P, Cheng LK (2015) Physiol Rev 95(2): 691-2
    › Primary publication · 25834235 (PubMed)
  16. Forward problem of electrocardiography: is it solved? Bear LR, Cheng LK, LeGrice IJ, Sands GB, Lever NA, Paterson DJ, Smaill BH (2015) Circ Arrhythm Electrophysiol 8(3): 677-84
    › Primary publication · 25834182 (PubMed)
  17. A Stochastic Algorithm for Generating Realistic Virtual Interstitial Cell of Cajal Networks. Gao J, Sathar S, O'Grady G, Archer R, Cheng LK (2015) IEEE Trans Biomed Eng 62(8): 2070-8
    › Primary publication · 25781477 (PubMed) · PMC4628824 (PubMed Central)
  18. Multi-channel wireless mapping of gastrointestinal serosal slow wave propagation. Paskaranandavadivel N, Wang R, Sathar S, O'Grady G, Cheng LK, Farajidavar A (2015) Neurogastroenterol Motil 27(4): 580-5
    › Primary publication · 25599978 (PubMed) · PMC4380526 (PubMed Central)
  19. A theoretical analysis of the electrogastrogram (EGG). Calder S, Cheng LK, Peng Du (2014) Conf Proc IEEE Eng Med Biol Soc : 4330-3
    › Primary publication · 25570950 (PubMed) · PMC4405628 (PubMed Central)
  20. A theoretical study of the initiation, maintenance and termination of gastric slow wave re-entry. Du P, Paskaranandavadivel N, O'Grady G, Tang SJ, Cheng LK (2015) Math Med Biol 32(4): 405-23
    › Primary publication · 25552487 (PubMed) · PMC4486628 (PubMed Central)
  21. Slow wave conduction patterns in the stomach: from Waller's foundations to current challenges. Cheng LK (2015) Acta Physiol (Oxf) 213(2): 384-93
    › Primary publication · 25313679 (PubMed) · PMC4405773 (PubMed Central)
  22. Recent progress in gastric arrhythmia: pathophysiology, clinical significance and future horizons. O'Grady G, Wang TH, Du P, Angeli T, Lammers WJ, Cheng LK (2014) Clin Exp Pharmacol Physiol 41(10): 854-62
    › Primary publication · 25115692 (PubMed) · PMC4359928 (PubMed Central)
  23. Developmental changes in postnatal murine intestinal interstitial cell of Cajal network structure and function. Gao J, Sathar S, O'Grady G, Han J, Cheng LK (2014) Ann Biomed Eng 42(8): 1729-39
    › Primary publication · 24866568 (PubMed) · PMC4106915 (PubMed Central)
  24. A system and method for online high-resolution mapping of gastric slow-wave activity. Bull SH, O'Grady G, Du P, Cheng LK (2014) IEEE Trans Biomed Eng 61(11): 2679-87
    › Primary publication · 24860024 (PubMed) · PMC4323276 (PubMed Central)
  25. Mitochondrial calcium handling within the interstitial cells of Cajal. Means SA, Cheng LK (2014) Am J Physiol Gastrointest Liver Physiol 307(1): G107-21
    › Primary publication · 24789203 (PubMed) · PMC4080165 (PubMed Central)
  26. Computational modeling of anoctamin 1 calcium-activated chloride channels as pacemaker channels in interstitial cells of Cajal. Lees-Green R, Gibbons SJ, Farrugia G, Sneyd J, Cheng LK (2014) Am J Physiol Gastrointest Liver Physiol 306(8): G711-27
    › Primary publication · 24481603 (PubMed) · PMC3989704 (PubMed Central)
  27. A biophysically based finite-state machine model for analyzing gastric experimental entrainment and pacing recordings. Sathar S, Trew ML, Du P, O'Grady G, Cheng LK (2014) Ann Biomed Eng 42(4): 858-70
    › Primary publication · 24276722 (PubMed) · PMC3972386 (PubMed Central)
  28. Reconstruction of normal and abnormal gastric electrical sources using a potential based inverse method. Kim JH, Du P, Cheng LK (2013) Physiol Meas 34(9): 1193-206
    › Primary publication · 24137714 (PubMed) · PMC4061470 (PubMed Central)
  29. Automated classification of spatiotemporal characteristics of gastric slow wave propagation. Paskaranandavadivel N, Gao J, Du P, O'Grady G, Cheng LK (2013) Conf Proc IEEE Eng Med Biol Soc : 7342-5
    › Primary publication · 24111441 (PubMed) · PMC4110486 (PubMed Central)
  30. A simplified biophysical cell model for gastric slow wave entrainment simulation. Du P, Gao J, O'Grady G, Cheng LK (2013) Conf Proc IEEE Eng Med Biol Soc : 6547-50
    › Primary publication · 24111242 (PubMed) · PMC4071156 (PubMed Central)
  31. Cellular automaton model for simulating tissue-specific intestinal electrophysiological activity. Gao J, Du P, O'Grady G, Archer R, Gibbons SJ, Farrugia G, Cheng LK (2013) Conf Proc IEEE Eng Med Biol Soc : 5537-40
    › Primary publication · 24110991 (PubMed) · PMC4058553 (PubMed Central)
  32. Are interstitial cells of Cajal involved in mechanical stress-induced gene expression and impairment of smooth muscle contractility in bowel obstruction? Wu CC, Lin YM, Gao J, Winston JH, Cheng LK, Shi XZ (2013) PLoS One 8(9): e76222
    › Primary publication · 24098782 (PubMed) · PMC3786942 (PubMed Central)
  33. Automated classification and identification of slow wave propagation patterns in gastric dysrhythmia. Paskaranandavadivel N, Gao J, Du P, O'Grady G, Cheng LK (2014) Ann Biomed Eng 42(1): 177-92
    › Primary publication · 24048711 (PubMed) · PMC3911879 (PubMed Central)
  34. Mapping and modeling gastrointestinal bioelectricity: from engineering bench to bedside. Cheng LK, Du P, O'Grady G (2013) Physiology (Bethesda) 28(5): 310-7
    › Primary publication · 23997190 (PubMed) · PMC3768093 (PubMed Central)
  35. Numerical metrics for automated quantification of interstitial cell of Cajal network structural properties. Gao J, Du P, O'Grady G, Archer R, Farrugia G, Gibbons SJ, Cheng LK (2013) J R Soc Interface 10(86): 20130421
    › Primary publication · 23804441 (PubMed) · PMC3730694 (PubMed Central)
  36. The bioelectrical basis and validity of gastrointestinal extracellular slow wave recordings. Angeli TR, Du P, Paskaranandavadivel N, Janssen PW, Beyder A, Lentle RG, Bissett IP, Cheng LK, O'Grady G (2013) J Physiol 591(18): 4567-79
    › Primary publication · 23713030 (PubMed) · PMC3784199 (PubMed Central)
  37. Experimental and Automated Analysis Techniques for High-resolution Electrical Mapping of Small Intestine Slow Wave Activity. Angeli TR, O'Grady G, Paskaranandavadivel N, Erickson JC, Du P, Pullan AJ, Bissett IP, Cheng LK (2013) J Neurogastroenterol Motil 19(2): 179-91
    › Primary publication · 23667749 (PubMed) · PMC3644654 (PubMed Central)
  38. Automated algorithm for GI spike burst detection and demonstration of efficacy in ischemic small intestine. Erickson JC, Velasco-Castedo R, Obioha C, Cheng LK, Angeli TR, O'Grady G (2013) Ann Biomed Eng 41(10): 2215-28
    › Primary publication · 23612912 (PubMed) · PMC3863806 (PubMed Central)
  39. Circumferential and functional re-entry of in vivo slow-wave activity in the porcine small intestine. Angeli TR, O'Grady G, Du P, Paskaranandavadivel N, Pullan AJ, Bissett IP, Cheng LK (2013) Neurogastroenterol Motil 25(5): e304-14
    › Primary publication · 23489929 (PubMed) · PMC3781238 (PubMed Central)
  40. Toward the virtual stomach: progress in multiscale modeling of gastric electrophysiology and motility. Du P, O'Grady G, Gao J, Sathar S, Cheng LK (2013) Wiley Interdiscip Rev Syst Biol Med 5(4): 481-93
    › Primary publication · 23463750 (PubMed) · PMC3681930 (PubMed Central)
  41. Comparison of filtering methods for extracellular gastric slow wave recordings. Paskaranandavadivel N, O'Grady G, Du P, Cheng LK (2013) Neurogastroenterol Motil 25(1): 79-83
    › Primary publication · 22974243 (PubMed) · PMC3535517 (PubMed Central)
  42. Reconstruction of multiple gastric electrical wave fronts using potential-based inverse methods. Kim JH, Pullan AJ, Cheng LK (2012) Phys Med Biol 57(16): 5205-19
    › Primary publication · 22842812 (PubMed) · PMC3423449 (PubMed Central)
  43. Rapid high-amplitude circumferential slow wave propagation during normal gastric pacemaking and dysrhythmias. O'Grady G, Du P, Paskaranandavadivel N, Angeli TR, Lammers WJ, Asirvatham SJ, Windsor JA, Farrugia G, Pullan AJ, Cheng LK (2012) Neurogastroenterol Motil 24(7): e299-312
    › Primary publication · 22709238 (PubMed) · PMC3383091 (PubMed Central)
  44. The gastrointestinal electrical mapping suite (GEMS): software for analyzing and visualizing high-resolution (multi-electrode) recordings in spatiotemporal detail. Yassi R, O'Grady G, Paskaranandavadivel N, Du P, Angeli TR, Pullan AJ, Cheng LK, Erickson JC (2012) BMC Gastroenterol : 60
    › Primary publication · 22672254 (PubMed) · PMC3464652 (PubMed Central)
  45. Abnormal initiation and conduction of slow-wave activity in gastroparesis, defined by high-resolution electrical mapping. O'Grady G, Angeli TR, Du P, Lahr C, Lammers WJEP, Windsor JA, Abell TL, Farrugia G, Pullan AJ, Cheng LK (2012) Gastroenterology 143(3): 589-598.e3
    › Primary publication · 22643349 (PubMed) · PMC3429650 (PubMed Central)
  46. A miniature bidirectional telemetry system for in vivo gastric slow wave recordings. Farajidavar A, O'Grady G, Rao SM, Cheng LK, Abell T, Chiao JC (2012) Physiol Meas 33(6): N29-37
    › Primary publication · 22635054 (PubMed) · PMC3399963 (PubMed Central)
  47. Influence of body parameters on gastric bioelectric and biomagnetic fields in a realistic volume conductor. Kim JH, Pullan AJ, Bradshaw LA, Cheng LK (2012) Physiol Meas 33(4): 545-56
    › Primary publication · 22415019 (PubMed) · PMC3359963 (PubMed Central)
  48. The analysis of human gastric pacemaker activity. O'Grady G, Pullan AJ, Cheng LK (2012) J Physiol 590(5): 1299-300; author reply 1301-2
    › Primary publication · 22399822 (PubMed) · PMC3381832 (PubMed Central)
  49. Mapping small intestine bioelectrical activity using high-resolution printed-circuit-board electrodes. Angeli TR, O'Grady G, Erickson JC, Du P, Paskaranandavadivel N, Bissett IP, Cheng LK, Pullan AJ (2011) Conf Proc IEEE Eng Med Biol Soc : 4951-4
    › Primary publication · 22255449 (PubMed) · PMC4076342 (PubMed Central)
  50. Quantification of velocity anisotropy during gastric electrical arrhythmia. Du P, O'Grady G, Paskaranandavadivel N, Angeli TR, Lahr C, Abell TL, Cheng LK, Pullan AJ (2011) Conf Proc IEEE Eng Med Biol Soc : 4402-5
    › Primary publication · 22255315 (PubMed) · PMC4127317 (PubMed Central)
  51. A framework for the online analysis of multi-electrode gastric slow wave recordings. Bull SH, O'Grady G, Cheng LK, Pullan AJ (2011) Conf Proc IEEE Eng Med Biol Soc : 1741-4
    › Primary publication · 22254663 (PubMed) · PMC4108589 (PubMed Central)
  52. Improved signal processing techniques for the analysis of high resolution serosal slow wave activity in the stomach. Paskaranandavadivel N, Cheng LK, Du P, O'Grady G, Pullan AJ (2011) Conf Proc IEEE Eng Med Biol Soc : 1737-40
    › Primary publication · 22254662 (PubMed) · PMC4071157 (PubMed Central)
  53. Reconstruction of multiple gastric electrical wave fronts using potential based inverse methods. Kim JH, Pullan AJ, Cheng LK (2011) Conf Proc IEEE Eng Med Biol Soc : 1355-8
    › Primary publication · 22254568 (PubMed) · PMC4129375 (PubMed Central)
  54. An improved method for the estimation and visualization of velocity fields from gastric high-resolution electrical mapping. Paskaranandavadivel N, O'Grady G, Du P, Pullan AJ, Cheng LK (2012) IEEE Trans Biomed Eng 59(3): 882-9
    › Primary publication · 22207635 (PubMed) · PMC4106919 (PubMed Central)
  55. A preliminary model of gastrointestinal electromechanical coupling. Du P, Poh YC, Lim JL, Gajendiran V, O'Grady G, Buist ML, Pullan AJ, Cheng LK (2011) IEEE Trans Biomed Eng 58(12): 3491-5
    › Primary publication · 21878406 (PubMed) · PMC4129377 (PubMed Central)
  56. A stochastic multi-scale model of electrical function in normal and depleted ICC networks. Gao J, Du P, Archer R, O'Grady G, Gibbons SJ, Farrugia G, Cheng LK, Pullan AJ (2011) IEEE Trans Biomed Eng 58(12): 3451-5
    › Primary publication · 21843981 (PubMed) · PMC3222726 (PubMed Central)
  57. High-resolution spatial analysis of slow wave initiation and conduction in porcine gastric dysrhythmia. O'Grady G, Egbuji JU, Du P, Lammers WJ, Cheng LK, Windsor JA, Pullan AJ (2011) Neurogastroenterol Motil 23(9): e345-55
    › Primary publication · 21714831 (PubMed) · PMC3156377 (PubMed Central)
  58. A comparison of gold versus silver electrode contacts for high-resolution gastric electrical mapping using flexible printed circuit board arrays. O'Grady G, Paskaranandavadivel N, Angeli TR, Du P, Windsor JA, Cheng LK, Pullan AJ (2011) Physiol Meas 32(3): N13-22
    › Primary publication · 21252419 (PubMed) · PMC4127313 (PubMed Central)
  59. Multiscale modeling of gastrointestinal electrophysiology and experimental validation. Du P, O'Grady G, Davidson JB, Cheng LK, Pullan AJ (2010) Crit Rev Biomed Eng 38(3): 225-54
    › Primary publication · 21133835 (PubMed) · PMC3090448 (PubMed Central)
  60. Effects of volume conductor and source configuration on simulated magnetogastrograms. Komuro R, Qiao W, Pullan AJ, Cheng LK (2010) Phys Med Biol 55(22): 6881-95
    › Primary publication · 21048291 (PubMed) · PMC4168013 (PubMed Central)
  61. A multiscale model of the electrophysiological basis of the human electrogastrogram. Du P, O'Grady G, Cheng LK, Pullan AJ (2010) Biophys J 99(9): 2784-92
    › Primary publication · 21044575 (PubMed) · PMC2965998 (PubMed Central)
  62. Automated gastric slow wave cycle partitioning and visualization for high-resolution activation time maps. Erickson JC, O'Grady G, Du P, Egbuji JU, Pullan AJ, Cheng LK (2011) Ann Biomed Eng 39(1): 469-83
    › Primary publication · 20927594 (PubMed) · PMC4127312 (PubMed Central)
  63. Gastrointestinal system. Cheng LK, O'Grady G, Du P, Egbuji JU, Windsor JA, Pullan AJ (2010) Wiley Interdiscip Rev Syst Biol Med 2(1): 65-79
    › Primary publication · 20836011 (PubMed) · PMC4221587 (PubMed Central)
  64. Origin, propagation and regional characteristics of porcine gastric slow wave activity determined by high-resolution mapping. Egbuji JU, O'Grady G, Du P, Cheng LK, Lammers WJ, Windsor JA, Pullan AJ (2010) Neurogastroenterol Motil 22(10): e292-300
    › Primary publication · 20618830 (PubMed) · PMC4110485 (PubMed Central)
  65. Origin and propagation of human gastric slow-wave activity defined by high-resolution mapping. O'Grady G, Du P, Cheng LK, Egbuji JU, Lammers WJ, Windsor JA, Pullan AJ (2010) Am J Physiol Gastrointest Liver Physiol 299(3): G585-92
    › Primary publication · 20595620 (PubMed) · PMC2950696 (PubMed Central)
  66. Tissue-specific mathematical models of slow wave entrainment in wild-type and 5-HT(2B) knockout mice with altered interstitial cells of Cajal networks. Du P, O'Grady G, Gibbons SJ, Yassi R, Lees-Green R, Farrugia G, Cheng LK, Pullan AJ (2010) Biophys J 98(9): 1772-81
    › Primary publication · 20441740 (PubMed) · PMC2862206 (PubMed Central)
  67. Three-dimensional high-resolution reconstruction of the human gastro-oesophageal junction. Yassi R, Cheng LK, Al-Ali S, Sands G, Gerneke D, LeGrice I, Pullan AJ, Windsor JA (2010) Clin Anat 23(3): 287-96
    › Primary publication · 20169612 (PubMed) · PMC4106913 (PubMed Central)
  68. Falling-edge, variable threshold (FEVT) method for the automated detection of gastric slow wave events in high-resolution serosal electrode recordings. Erickson JC, O'Grady G, Du P, Obioha C, Qiao W, Richards WO, Bradshaw LA, Pullan AJ, Cheng LK (2010) Ann Biomed Eng 38(4): 1511-29
    › Primary publication · 20024624 (PubMed) · PMC2855965 (PubMed Central)