None provided


The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Role of adenosine A2B receptor signaling in contribution of cardiac mesenchymal stem-like cells to myocardial scar formation. Ryzhov S, Sung BH, Zhang Q, Weaver A, Gumina RJ, Biaggioni I, Feoktistov I (2014) Purinergic Signal 10(3): 477-86
    › Primary publication · 24584483 (PubMed) · PMC4152448 (PubMed Central)
  2. Type of Valvular Heart Disease Requiring Surgery in the 21st Century: Mortality and Length-of-Stay Related to Surgery. Boudoulas KD, Ravi Y, Garcia D, Saini U, Sofowora GG, Gumina RJ, Sai-Sudhakar CB (2013) Open Cardiovasc Med J : 104-9
    › Primary publication · 24339838 (PubMed) · PMC3856389 (PubMed Central)
  3. Preconditioning mesenchymal stem cells with caspase inhibition and hyperoxia prior to hypoxia exposure increases cell proliferation. Saini U, Gumina RJ, Wolfe B, Kuppusamy ML, Kuppusamy P, Boudoulas KD (2013) J Cell Biochem 114(11): 2612-23
    › Primary publication · 23794477 (PubMed) · PMC4017598 (PubMed Central)
  4. Comparison of Impella and intra-aortic balloon pump in high-risk percutaneous coronary intervention: vascular complications and incidence of bleeding. Boudoulas KD, Pederzolli A, Saini U, Gumina RJ, Mazzaferri EL, Davis M, Bush CA, Capers Q, Magorien R, Pompili VJ (2012) Acute Card Care 14(4): 120-4
    › Primary publication · 23215746 (PubMed)
  5. Changes in plasma profiles of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in stress-induced cardiomyopathy. Essa EM, Zile MR, Stroud RE, Rice A, Gumina RJ, Leier CV, Spinale FG (2012) J Card Fail 18(6): 487-92
    › Primary publication · 22633307 (PubMed) · PMC3361732 (PubMed Central)
  6. Ectonucleotide triphosphate diphosphohydrolase-1 (CD39) mediates resistance to occlusive arterial thrombus formation after vascular injury in mice. Huttinger ZM, Milks MW, Nickoli MS, Aurand WL, Long LC, Wheeler DG, Dwyer KM, d'Apice AJ, Robson SC, Cowan PJ, Gumina RJ (2012) Am J Pathol 181(1): 322-33
    › Primary publication · 22613024 (PubMed) · PMC3388153 (PubMed Central)
  7. Transgenic swine: expression of human CD39 protects against myocardial injury. Wheeler DG, Joseph ME, Mahamud SD, Aurand WL, Mohler PJ, Pompili VJ, Dwyer KM, Nottle MB, Harrison SJ, d'Apice AJ, Robson SC, Cowan PJ, Gumina RJ (2012) J Mol Cell Cardiol 52(5): 958-61
    › Primary publication · 22269791 (PubMed) · PMC3327755 (PubMed Central)
  8. Transgenic over expression of ectonucleotide triphosphate diphosphohydrolase-1 protects against murine myocardial ischemic injury. Cai M, Huttinger ZM, He H, Zhang W, Li F, Goodman LA, Wheeler DG, Druhan LJ, Zweier JL, Dwyer KM, He G, d'Apice AJ, Robson SC, Cowan PJ, Gumina RJ (2011) J Mol Cell Cardiol 51(6): 927-35
    › Primary publication · 21939667 (PubMed) · PMC3245748 (PubMed Central)
  9. Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation. Cunha SR, Hund TJ, Hashemi S, Voigt N, Li N, Wright P, Koval O, Li J, Gudmundsson H, Gumina RJ, Karck M, Schott JJ, Probst V, Le Marec H, Anderson ME, Dobrev D, Wehrens XH, Mohler PJ (2011) Circulation 124(11): 1212-22
    › Primary publication · 21859974 (PubMed) · PMC3211046 (PubMed Central)
  10. Cardiovascular magnetic resonance in wet beriberi. Essa E, Velez MR, Smith S, Giri S, Raman SV, Gumina RJ (2011) J Cardiovasc Magn Reson : 41
    › Primary publication · 21838901 (PubMed) · PMC3175447 (PubMed Central)
  11. Myocardial bridging in an adult patient with d-transposition of the great arteries. Zaidi AN, Gumina RJ (2011) Congenit Heart Dis 6(2): 157-61
    › Primary publication · 21426527 (PubMed)
  12. Antioxidant network expression abrogates oxidative posttranslational modifications in mice. Mital R, Zhang W, Cai M, Huttinger ZM, Goodman LA, Wheeler DG, Ziolo MT, Dwyer KM, d'Apice AJ, Zweier JL, He G, Cowan PJ, Gumina RJ (2011) Am J Physiol Heart Circ Physiol 300(5): H1960-70
    › Primary publication · 21335461 (PubMed) · PMC3094079 (PubMed Central)
  13. Effect on ex vivo platelet aggregation and in vivo cyclic flow with Na+/H+ exchange inhibition: Gumina, NHE-1 inhibition and platelet aggregation. Gumina RJ, Newman PJ, Gross GJ (2011) J Thromb Thrombolysis 31(4): 431-5
    › Primary publication · 21082215 (PubMed) · PMC3096849 (PubMed Central)
  14. Survival benefit with concomitant clopidogrel and glycoprotein IIb/IIIa inhibitor therapy at ad hoc percutaneous coronary intervention. Gumina RJ, Yang EH, Sandhu GS, Prasad A, Bresnahan JF, Lennon RJ, Rihal CS, Holmes DR, Singh M (2008) Mayo Clin Proc 83(9): 995-1001
    › Primary publication · 18775199 (PubMed)
  15. Progression of nonculprit plaque stenosis following successful percutaneous intervention. Bunch TJ, Rihal CS, Gumina RJ, Cooper L, Caplice NM (2008) Angiology 59(2): 236-9
    › Primary publication · 18388075 (PubMed)
  16. New trials and therapies for acute myocardial infarction. Gumina RJ (2007) Med Clin North Am 91(4): 729-49; xii
    › Primary publication · 17640545 (PubMed)
  17. Bland-White-Garland syndrome: not just a pediatric coronary anomaly. Gumina RJ, Callahan MJ, Murphy JG (2007) J Invasive Cardiol 19(1): E9
    › Primary publication · 17297194 (PubMed)
  18. KATP channel knockout worsens myocardial calcium stress load in vivo and impairs recovery in stunned heart. Gumina RJ, O'Cochlain DF, Kurtz CE, Bast P, Pucar D, Mishra P, Miki T, Seino S, Macura S, Terzic A (2007) Am J Physiol Heart Circ Physiol 292(4): H1706-13
    › Primary publication · 17189350 (PubMed)
  19. Long-term survival after right ventricular infarction. Gumina RJ, Murphy JG, Rihal CS, Lennon RJ, Wright RS (2006) Am J Cardiol 98(12): 1571-3
    › Primary publication · 17145212 (PubMed)
  20. Cardioprotective-mimetics reduce myocardial infarct size in animals resistant to ischemic preconditioning. Gumina RJ, El Schultz J, Moore J, Beier N, Schelling P, Gross GJ (2005) Cardiovasc Drugs Ther 19(5): 315-22
    › Primary publication · 16382293 (PubMed)
  21. Emergency coronary artery bypass surgery for percutaneous coronary interventions: changes in the incidence, clinical characteristics, and indications from 1979 to 2003. Yang EH, Gumina RJ, Lennon RJ, Holmes DR, Rihal CS, Singh M (2005) J Am Coll Cardiol 46(11): 2004-9
    › Primary publication · 16325032 (PubMed)
  22. Mapping hypoxia-induced bioenergetic rearrangements and metabolic signaling by 18O-assisted 31P NMR and 1H NMR spectroscopy. Pucar D, Dzeja PP, Bast P, Gumina RJ, Drahl C, Lim L, Juranic N, Macura S, Terzic A (2004) Mol Cell Biochem 256-257(1-2): 281-9
    › Primary publication · 14977188 (PubMed) · PMC2743901 (PubMed Central)
  23. Cellular remodeling in heart failure disrupts K(ATP) channel-dependent stress tolerance. Hodgson DM, Zingman LV, Kane GC, Perez-Terzic C, Bienengraeber M, Ozcan C, Gumina RJ, Pucar D, O'Coclain F, Mann DL, Alekseev AE, Terzic A (2003) EMBO J 22(8): 1732-42
    › Primary publication · 12682006 (PubMed) · PMC154482 (PubMed Central)
  24. Knockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energetics. Gumina RJ, Pucar D, Bast P, Hodgson DM, Kurtz CE, Dzeja PP, Miki T, Seino S, Terzic A (2003) Am J Physiol Heart Circ Physiol 284(6): H2106-13
    › Primary publication · 12598229 (PubMed)
  25. Strong predictive value of TIMI risk score analysis for in-hospital and long-term survival of patients with right ventricular infarction. Gumina RJ, Wright RS, Kopecky SL, Miller WL, Williams BA, Reeder GS, Murphy JG (2002) Eur Heart J 23(21): 1678-83
    › Primary publication · 12398825 (PubMed)
  26. Polycythemia vera--a case report and discussion on pathogenic mechanisms of increased thrombosis. Gumina RJ, Foley DA, Tefferi A, Rooke TW, Shields RC (2002) Angiology 53(5): 587-91
    › Primary publication · 12365868 (PubMed)
  27. Kir6.2 is required for adaptation to stress. Zingman LV, Hodgson DM, Bast PH, Kane GC, Perez-Terzic C, Gumina RJ, Pucar D, Bienengraeber M, Dzeja PP, Miki T, Seino S, Alekseev AE, Terzic A (2002) Proc Natl Acad Sci U S A 99(20): 13278-83
    › Primary publication · 12271142 (PubMed) · PMC130624 (PubMed Central)
  28. Adenylate kinase AK1 knockout heart: energetics and functional performance under ischemia-reperfusion. Pucar D, Bast P, Gumina RJ, Lim L, Drahl C, Juranic N, Macura S, Janssen E, Wieringa B, Terzic A, Dzeja PP (2002) Am J Physiol Heart Circ Physiol 283(2): H776-82
    › Primary publication · 12124227 (PubMed)
  29. Do NHE inhibition and ischemic preconditioning convey cardioprotection through a common mechanism? Gumina RJ, Terzic A, Gross GJ (2001) Basic Res Cardiol 96(4): 318-24
    › Primary publication · 11518187 (PubMed)
  30. Na(+)/H(+) exchange inhibition prevents endothelial dysfunction after I/R injury. Gumina RJ, Moore J, Schelling P, Beier N, Gross GJ (2001) Am J Physiol Heart Circ Physiol 281(3): H1260-6
    › Primary publication · 11514295 (PubMed)
  31. Cardioprotection: emerging pharmacotherapy. Gumina RJ, Jahangir A, Gross GJ, Terzic A (2001) Expert Opin Pharmacother 2(5): 739-52
    › Primary publication · 11336619 (PubMed)
  32. Determination of cytochrome P450 metabolites of arachidonic acid in coronary venous plasma during ischemia and reperfusion in dogs. Nithipatikom K, DiCamelli RF, Kohler S, Gumina RJ, Falck JR, Campbell WB, Gross GJ (2001) Anal Biochem 292(1): 115-24
    › Primary publication · 11319825 (PubMed)
  33. Na(+)/H(+) exchange inhibition-induced cardioprotection in dogs: effects on neutrophils versus cardiomyocytes. Gumina RJ, Auchampach J, Wang R, Buerger E, Eickmeier C, Moore J, Daemmgen J, Gross GJ (2000) Am J Physiol Heart Circ Physiol 279(4): H1563-70
    › Primary publication · 11009442 (PubMed)
  34. Inhibitors of ischemic preconditioning do not attenuate Na+/H+ exchange inhibitor mediated cardioprotection. Gumina RJ, Beier N, Schelling P, Gross GJ (2000) J Cardiovasc Pharmacol 35(6): 949-53
    › Primary publication · 10836732 (PubMed)
  35. Inhibition of the Na(+)/H(+) exchanger attenuates phase 1b ischemic arrhythmias and reperfusion-induced ventricular fibrillation. Gumina RJ, Daemmgen J, Gross GJ (2000) Eur J Pharmacol 396(2-3): 119-24
    › Primary publication · 10822064 (PubMed)
  36. Inhibition of the Na(+)/H(+) exchanger confers greater cardioprotection against 90 minutes of myocardial ischemia than ischemic preconditioning in dogs. Gumina RJ, Buerger E, Eickmeier C, Moore J, Daemmgen J, Gross GJ (1999) Circulation 100(25): 2519-26; discussion 2469-72
    › Primary publication · 10604890 (PubMed)
  37. If ischemic preconditioning is the gold standard, has a platinum standard of cardioprotection arrived? Comparison with NHE inhibition. Gumina RJ, Gross GJ (1999) J Thromb Thrombolysis 8(1): 39-44
    › Primary publication · 10481213 (PubMed)
  38. A new sodium/hydrogen exchange inhibitor, EMD 85131, limits infarct size in dogs when administered before or after coronary artery occlusion. Gumina RJ, Mizumura T, Beier N, Schelling P, Schultz JJ, Gross GJ (1998) J Pharmacol Exp Ther 286(1): 175-83
    › Primary publication · 9655858 (PubMed)
  39. The leukocyte cell adhesion cascade and its role in myocardial ischemia-reperfusion injury. Gumina RJ, Newman PJ, Kenny D, Warltier DC, Gross GJ (1997) Basic Res Cardiol 92(4): 201-13
    › Primary publication · 9342427 (PubMed)
  40. Characterization of the human platelet/endothelial cell adhesion molecule-1 promoter: identification of a GATA-2 binding element required for optimal transcriptional activity. Gumina RJ, Kirschbaum NE, Piotrowski K, Newman PJ (1997) Blood 89(4): 1260-9
    › Primary publication · 9028949 (PubMed)
  41. Antibody to platelet/endothelial cell adhesion molecule-1 reduces myocardial infarct size in a rat model of ischemia-reperfusion injury. Gumina RJ, el Schultz J, Yao Z, Kenny D, Warltier DC, Newman PJ, Gross GJ (1996) Circulation 94(12): 3327-33
    › Primary publication · 8989147 (PubMed)
  42. The human PECAM1 gene maps to 17q23. Gumina RJ, Kirschbaum NE, Rao PN, vanTuinen P, Newman PJ (1996) Genomics 34(2): 229-32
    › Primary publication · 8661055 (PubMed)
  43. Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain. Kirschbaum NE, Gumina RJ, Newman PJ (1994) Blood 84(12): 4028-37
    › Primary publication · 7994021 (PubMed)
  44. Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations. Gray PW, Flaggs G, Leong SR, Gumina RJ, Weiss J, Ooi CE, Elsbach P (1989) J Biol Chem 264(16): 9505-9
    › Primary publication · 2722846 (PubMed)
  45. Transduction of the IFN-gamma signal for HLA-DR expression in the promonocytic line THP-1 involves a late-acting PKC activity. Gumina RJ, Freire-Moar J, DeYoung L, Webb DR, Devens BH (1991) Cell Immunol 138(2): 265-79
    › Primary publication · 1934072 (PubMed)