Joshua Denny
Last active: 3/14/2018

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Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Phenome-Wide Association Studies Uncover a Novel Association of Increased Atrial Fibrillation in Male Patients With Systemic Lupus Erythematosus. Barnado A, Carroll RJ, Casey C, Wheless L, Denny JC, Crofford LJ (2018) Arthritis Care Res (Hoboken) 70(11): 1630-1636
    › Primary publication · 29481723 (PubMed) · PMC6109620 (PubMed Central)
  2. Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects. Volpi S, Bult CJ, Chisholm RL, Deverka PA, Ginsburg GS, Jacob HJ, Kasapi M, McLeod HL, Roden DM, Williams MS, Green ED, Rodriguez LL, Aronson S, Cavallari LH, Denny JC, Dressler LG, Johnson JA, Klein TE, Leeder JS, Piquette-Miller M, Perera M, Rasmussen-Torvik LJ, Rehm HL, Ritchie MD, Skaar TC, Wagle N, Weinshilboum R, Weitzel KW, Wildin R, Wilson J, Manolio TA, Relling MV (2018) Clin Pharmacol Ther 103(5): 778-786
    › Primary publication · 29460415 (PubMed) · PMC5902434 (PubMed Central)
  3. Calcium channel blockers as drug repurposing candidates for gestational diabetes: Mining large scale genomic and electronic health records data to repurpose medications. Goldstein JA, Bastarache LA, Denny JC, Roden DM, Pulley JM, Aronoff DM (2018) Pharmacol Res : 44-51
    › Primary publication · 29448118 (PubMed) · PMC5965292 (PubMed Central)
  4. MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank. Li X, Meng X, Spiliopoulou A, Timofeeva M, Wei WQ, Gifford A, Shen X, He Y, Varley T, McKeigue P, Tzoulaki I, Wright AF, Joshi P, Denny JC, Campbell H, Theodoratou E (2018) Ann Rheum Dis 77(7): 1039-1047
    › Primary publication · 29437585 (PubMed) · PMC6029646 (PubMed Central)
  5. An integrative functional genomics framework for effective identification of novel regulatory variants in genome-phenome studies. Zhao J, Cheng F, Jia P, Cox N, Denny JC, Zhao Z (2018) Genome Med 10(1): 7
    › Primary publication · 29378629 (PubMed) · PMC5789733 (PubMed Central)
  6. Benefit of Preemptive Pharmacogenetic Information on Clinical Outcome. Roden DM, Van Driest SL, Mosley JD, Wells QS, Robinson JR, Denny JC, Peterson JF (2018) Clin Pharmacol Ther 103(5): 787-794
    › Primary publication · 29377064 (PubMed) · PMC6134843 (PubMed Central)
  7. SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation. White KD, Abe R, Ardern-Jones M, Beachkofsky T, Bouchard C, Carleton B, Chodosh J, Cibotti R, Davis R, Denny JC, Dodiuk-Gad RP, Ergen EN, Goldman JL, Holmes JH, Hung SI, Lacouture ME, Lehloenya RJ, Mallal S, Manolio TA, Micheletti RG, Mitchell CM, Mockenhaupt M, Ostrov DA, Pavlos R, Pirmohamed M, Pope E, Redwood A, Rosenbach M, Rosenblum MD, Roujeau JC, Saavedra AP, Saeed HN, Struewing JP, Sueki H, Sukasem C, Sung C, Trubiano JA, Weintraub J, Wheatley LM, Williams KB, Worley B, Chung WH, Shear NH, Phillips EJ (2018) J Allergy Clin Immunol Pract 6(1): 38-69
    › Primary publication · 29310768 (PubMed) · PMC5857362 (PubMed Central)
  8. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, Mahajan A, Marouli E, Sivapalaratnam S, Young KL, Alfred T, Feitosa MF, Masca NGD, Manning AK, Medina-Gomez C, Mudgal P, Ng MCY, Reiner AP, Vedantam S, Willems SM, Winkler TW, Abecasis G, Aben KK, Alam DS, Alharthi SE, Allison M, Amouyel P, Asselbergs FW, Auer PL, Balkau B, Bang LE, Barroso I, Bastarache L, Benn M, Bergmann S, Bielak LF, Blüher M, Boehnke M, Boeing H, Boerwinkle E, Böger CA, Bork-Jensen J, Bots ML, Bottinger EP, Bowden DW, Brandslund I, Breen G, Brilliant MH, Broer L, Brumat M, Burt AA, Butterworth AS, Campbell PT, Cappellani S, Carey DJ, Catamo E, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Chowdhury R, Christensen C, Chu AY, Cocca M, Collins FS, Cook JP, Corley J, Corominas Galbany J, Cox AJ, Crosslin DS, Cuellar-Partida G, D'Eustacchio A, Danesh J, Davies G, Bakker PIW, Groot MCH, Mutsert R, Deary IJ, Dedoussis G, Demerath EW, Heijer M, Hollander AI, Ruijter HM, Dennis JG, Denny JC, Di Angelantonio E, Drenos F, Du M, Dubé MP, Dunning AM, Easton DF, Edwards TL, Ellinghaus D, Ellinor PT, Elliott P, Evangelou E, Farmaki AE, Farooqi IS, Faul JD, Fauser S, Feng S, Ferrannini E, Ferrieres J, Florez JC, Ford I, Fornage M, Franco OH, Franke A, Franks PW, Friedrich N, Frikke-Schmidt R, Galesloot TE, Gan W, Gandin I, Gasparini P, Gibson J, Giedraitis V, Gjesing AP, Gordon-Larsen P, Gorski M, Grabe HJ, Grant SFA, Grarup N, Griffiths HL, Grove ML, Gudnason V, Gustafsson S, Haessler J, Hakonarson H, Hammerschlag AR, Hansen T, Harris KM, Harris TB, Hattersley AT, Have CT, Hayward C, He L, Heard-Costa NL, Heath AC, Heid IM, Helgeland Ø, Hernesniemi J, Hewitt AW, Holmen OL, Hovingh GK, Howson JMM, Hu Y, Huang PL, Huffman JE, Ikram MA, Ingelsson E, Jackson AU, Jansson JH, Jarvik GP, Jensen GB, Jia Y, Johansson S, Jørgensen ME, Jørgensen T, Jukema JW, Kahali B, Kahn RS, Kähönen M, Kamstrup PR, Kanoni S, Kaprio J, Karaleftheri M, Kardia SLR, Karpe F, Kathiresan S, Kee F, Kiemeney LA, Kim E, Kitajima H, Komulainen P, Kooner JS, Kooperberg C, Korhonen T, Kovacs P, Kuivaniemi H, Kutalik Z, Kuulasmaa K, Kuusisto J, Laakso M, Lakka TA, Lamparter D, Lange EM, Lange LA, Langenberg C, Larson EB, Lee NR, Lehtimäki T, Lewis CE, Li H, Li J, Li-Gao R, Lin H, Lin KH, Lin LA, Lin X, Lind L, Lindström J, Linneberg A, Liu CT, Liu DJ, Liu Y, Lo KS, Lophatananon A, Lotery AJ, Loukola A, Luan J, Lubitz SA, Lyytikäinen LP, Männistö S, Marenne G, Mazul AL, McCarthy MI, McKean-Cowdin R, Medland SE, Meidtner K, Milani L, Mistry V, Mitchell P, Mohlke KL, Moilanen L, Moitry M, Montgomery GW, Mook-Kanamori DO, Moore C, Mori TA, Morris AD, Morris AP, Müller-Nurasyid M, Munroe PB, Nalls MA, Narisu N, Nelson CP, Neville M, Nielsen SF, Nikus K, Njølstad PR, Nordestgaard BG, Nyholt DR, O'Connel JR, O'Donoghue ML, Olde Loohuis LM, Ophoff RA, Owen KR, Packard CJ, Padmanabhan S, Palmer CNA, Palmer ND, Pasterkamp G, Patel AP, Pattie A, Pedersen O, Peissig PL, Peloso GM, Pennell CE, Perola M, Perry JA, Perry JRB, Pers TH, Person TN, Peters A, Petersen ERB, Peyser PA, Pirie A, Polasek O, Polderman TJ, Puolijoki H, Raitakari OT, Rasheed A, Rauramaa R, Reilly DF, Renström F, Rheinberger M, Ridker PM, Rioux JD, Rivas MA, Roberts DJ, Robertson NR, Robino A, Rolandsson O, Rudan I, Ruth KS, Saleheen D, Salomaa V, Samani NJ, Sapkota Y, Sattar N, Schoen RE, Schreiner PJ, Schulze MB, Scott RA, Segura-Lepe MP, Shah SH, Sheu WH, Sim X, Slater AJ, Small KS, Smith AV, Southam L, Spector TD, Speliotes EK, Starr JM, Stefansson K, Steinthorsdottir V, Stirrups KE, Strauch K, Stringham HM, Stumvoll M, Sun L, Surendran P, Swift AJ, Tada H, Tansey KE, Tardif JC, Taylor KD, Teumer A, Thompson DJ, Thorleifsson G, Thorsteinsdottir U, Thuesen BH, Tönjes A, Tromp G, Trompet S, Tsafantakis E, Tuomilehto J, Tybjaerg-Hansen A, Tyrer JP, Uher R, Uitterlinden AG, Uusitupa M, Laan SW, Duijn CM, Leeuwen N, van Setten J, Vanhala M, Varbo A, Varga TV, Varma R, Velez Edwards DR, Vermeulen SH, Veronesi G, Vestergaard H, Vitart V, Vogt TF, Völker U, Vuckovic D, Wagenknecht LE, Walker M, Wallentin L, Wang F, Wang CA, Wang S, Wang Y, Ware EB, Wareham NJ, Warren HR, Waterworth DM, Wessel J, White HD, Willer CJ, Wilson JG, Witte DR, Wood AR, Wu Y, Yaghootkar H, Yao J, Yao P, Yerges-Armstrong LM, Young R, Zeggini E, Zhan X, Zhang W, Zhao JH, Zhao W, Zhao W, Zhou W, Zondervan KT, CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, EPIC InterAct Consortium, INTERVAL Study, ReproGen Consortium, T2D-Genes Consortium, MAGIC Investigators, Understanding Society Scientific Group, Rotter JI, Pospisilik JA, Rivadeneira F, Borecki IB, Deloukas P, Frayling TM, Lettre G, North KE, Lindgren CM, Hirschhorn JN, Loos RJF (2018) Nat Genet 50(1): 26-41
    › Primary publication · 29273807 (PubMed) · PMC5945951 (PubMed Central)
  9. PRECISION MEDICINE: FROM DIPLOTYPES TO DISPARITIES TOWARDS IMPROVED HEALTH AND THERAPIES. Crawford DC, Morgan AA, Denny JC, Aronow BJ, Brenner SE (2018) Pac Symp Biocomput : 389-399
    › Primary publication · 29218899 (PubMed) · PMC6182117 (PubMed Central)
  10. Using Human 'Experiments of Nature' to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors. Jerome RN, Pulley JM, Roden DM, Shirey-Rice JK, Bastarache LA, R Bernard G, B Ekstrom L, Lancaster WJ, Denny JC (2018) Drug Saf 41(3): 303-311
    › Primary publication · 29185237 (PubMed) · PMC5828879 (PubMed Central)
  11. The Influence of Big (Clinical) Data and Genomics on Precision Medicine and Drug Development. Denny JC, Van Driest SL, Wei WQ, Roden DM (2018) Clin Pharmacol Ther 103(3): 409-418
    › Primary publication · 29171014 (PubMed) · PMC5805632 (PubMed Central)
  12. Genome-wide and Phenome-wide Approaches to Understand Variable Drug Actions in Electronic Health Records. Robinson JR, Denny JC, Roden DM, Van Driest SL (2018) Clin Transl Sci 11(2): 112-122
    › Primary publication · 29148204 (PubMed) · PMC5866959 (PubMed Central)
  13. Research Directions in Genetic Predispositions to Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis. Manolio TA, Hutter CM, Avigan M, Cibotti R, Davis RL, Denny JC, Grenade L, Wheatley LM, Carrington MN, Chantratita W, Chung WH, Dalton AD, Hung SI, Lee MTM, Leeder JS, Lertora JJL, Mahasirimongkol S, McLeod HL, Mockenhaupt M, Pacanowski M, Phillips EJ, Pinheiro S, Pirmohamed M, Sung C, Suwankesawong W, Trepanier L, Tumminia SJ, Veenstra D, Yuliwulandari R, Shear NH (2018) Clin Pharmacol Ther 103(3): 390-394
    › Primary publication · 29105735 (PubMed) · PMC5805563 (PubMed Central)
  14. Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention. Cavallari LH, Lee CR, Beitelshees AL, Cooper-DeHoff RM, Duarte JD, Voora D, Kimmel SE, McDonough CW, Gong Y, Dave CV, Pratt VM, Alestock TD, Anderson RD, Alsip J, Ardati AK, Brott BC, Brown L, Chumnumwat S, Clare-Salzler MJ, Coons JC, Denny JC, Dillon C, Elsey AR, Hamadeh IS, Harada S, Hillegass WB, Hines L, Horenstein RB, Howell LA, Jeng LJB, Kelemen MD, Lee YM, Magvanjav O, Montasser M, Nelson DR, Nutescu EA, Nwaba DC, Pakyz RE, Palmer K, Peterson JF, Pollin TI, Quinn AH, Robinson SW, Schub J, Skaar TC, Smith DM, Sriramoju VB, Starostik P, Stys TP, Stevenson JM, Varunok N, Vesely MR, Wake DT, Weck KE, Weitzel KW, Wilke RA, Willig J, Zhao RY, Kreutz RP, Stouffer GA, Empey PE, Limdi NA, Shuldiner AR, Winterstein AG, Johnson JA, IGNITE Network (2018) JACC Cardiovasc Interv 11(2): 181-191
    › Primary publication · 29102571 (PubMed) · PMC5775044 (PubMed Central)
  15. Exome-wide association study of plasma lipids in >300,000 individuals. Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, Baber U, Ballantyne CM, Bang LE, Benn M, Bis JC, Boehnke M, Boerwinkle E, Bork-Jensen J, Bottinger EP, Brandslund I, Brown M, Busonero F, Caulfield MJ, Chambers JC, Chasman DI, Chen YE, Chen YI, Chowdhury R, Christensen C, Chu AY, Connell JM, Cucca F, Cupples LA, Damrauer SM, Davies G, Deary IJ, Dedoussis G, Denny JC, Dominiczak A, Dubé MP, Ebeling T, Eiriksdottir G, Esko T, Farmaki AE, Feitosa MF, Ferrario M, Ferrieres J, Ford I, Fornage M, Franks PW, Frayling TM, Frikke-Schmidt R, Fritsche LG, Frossard P, Fuster V, Ganesh SK, Gao W, Garcia ME, Gieger C, Giulianini F, Goodarzi MO, Grallert H, Grarup N, Groop L, Grove ML, Gudnason V, Hansen T, Harris TB, Hayward C, Hirschhorn JN, Holmen OL, Huffman J, Huo Y, Hveem K, Jabeen S, Jackson AU, Jakobsdottir J, Jarvelin MR, Jensen GB, Jørgensen ME, Jukema JW, Justesen JM, Kamstrup PR, Kanoni S, Karpe F, Kee F, Khera AV, Klarin D, Koistinen HA, Kooner JS, Kooperberg C, Kuulasmaa K, Kuusisto J, Laakso M, Lakka T, Langenberg C, Langsted A, Launer LJ, Lauritzen T, Liewald DCM, Lin LA, Linneberg A, Loos RJF, Lu Y, Lu X, Mägi R, Malarstig A, Manichaikul A, Manning AK, Mäntyselkä P, Marouli E, Masca NGD, Maschio A, Meigs JB, Melander O, Metspalu A, Morris AP, Morrison AC, Mulas A, Müller-Nurasyid M, Munroe PB, Neville MJ, Nielsen JB, Nielsen SF, Nordestgaard BG, Ordovas JM, Mehran R, O'Donnell CJ, Orho-Melander M, Molony CM, Muntendam P, Padmanabhan S, Palmer CNA, Pasko D, Patel AP, Pedersen O, Perola M, Peters A, Pisinger C, Pistis G, Polasek O, Poulter N, Psaty BM, Rader DJ, Rasheed A, Rauramaa R, Reilly DF, Reiner AP, Renström F, Rich SS, Ridker PM, Rioux JD, Robertson NR, Roden DM, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sanna S, Sattar N, Schmidt EM, Scott RA, Sever P, Sevilla RS, Shaffer CM, Sim X, Sivapalaratnam S, Small KS, Smith AV, Smith BH, Somayajula S, Southam L, Spector TD, Speliotes EK, Starr JM, Stirrups KE, Stitziel N, Strauch K, Stringham HM, Surendran P, Tada H, Tall AR, Tang H, Tardif JC, Taylor KD, Trompet S, Tsao PS, Tuomilehto J, Tybjaerg-Hansen A, van Zuydam NR, Varbo A, Varga TV, Virtamo J, Waldenberger M, Wang N, Wareham NJ, Warren HR, Weeke PE, Weinstock J, Wessel J, Wilson JG, Wilson PWF, Xu M, Yaghootkar H, Young R, Zeggini E, Zhang H, Zheng NS, Zhang W, Zhang Y, Zhou W, Zhou Y, Zoledziewska M, Charge Diabetes Working Group, EPIC-InterAct Consortium, EPIC-CVD Consortium, GOLD Consortium, VA Million Veteran Program, Howson JMM, Danesh J, McCarthy MI, Cowan CA, Abecasis G, Deloukas P, Musunuru K, Willer CJ, Kathiresan S (2017) Nat Genet 49(12): 1758-1766
    › Primary publication · 29083408 (PubMed) · PMC5709146 (PubMed Central)
  16. Representing Knowledge Consistently Across Health Systems. Rosenbloom ST, Carroll RJ, Warner JL, Matheny ME, Denny JC (2017) Yearb Med Inform 26(1): 139-147
    › Primary publication · 29063555 (PubMed) · PMC6239235 (PubMed Central)
  17. The Gain-of-Function Integrin β3 Pro33 Variant Alters the Serotonin System in the Mouse Brain. Dohn MR, Kooker CG, Bastarache L, Jessen T, Rinaldi C, Varney S, Mazalouskas MD, Pan H, Oliver KH, Velez Edwards DR, Sutcliffe JS, Denny JC, Carneiro AMD (2017) J Neurosci 37(46): 11271-11284
    › Primary publication · 29038237 (PubMed) · PMC5688530 (PubMed Central)
  18. Mining 100 million notes to find homelessness and adverse childhood experiences: 2 case studies of rare and severe social determinants of health in electronic health records. Bejan CA, Angiolillo J, Conway D, Nash R, Shirey-Rice JK, Lipworth L, Cronin RM, Pulley J, Kripalani S, Barkin S, Johnson KB, Denny JC (2018) J Am Med Inform Assoc 25(1): 61-71
    › Primary publication · 29016793 (PubMed) · PMC6080810 (PubMed Central)
  19. Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans. Hellwege JN, Jeff JM, Wise LA, Gallagher CS, Wellons M, Hartmann KE, Jones SF, Torstenson ES, Dickinson S, Ruiz-Narváez EA, Rohland N, Allen A, Reich D, Tandon A, Pasaniuc B, Mancuso N, Im HK, Hinds DA, Palmer JR, Rosenberg L, Denny JC, Roden DM, Stewart EA, Morton CC, Kenny EE, Edwards TL, Velez Edwards DR (2017) Hum Genet 136(11-12): 1497-1498
    › Primary publication · 28975356 (PubMed) · PMC5909202 (PubMed Central)
  20. Prototype Development: Context-Driven Dynamic XML Ophthalmologic Data Capture Application. Peissig P, Schwei KM, Kadolph C, Finamore J, Cancel E, McCarty CA, Okorie A, Thomas KL, Allen Pacheco J, Pathak J, Ellis SB, Denny JC, Rasmussen LV, Tromp G, Williams MS, Vrabec TR, Brilliant MH (2017) JMIR Med Inform 5(3): e27
    › Primary publication · 28903894 (PubMed) · PMC5617903 (PubMed Central)
  21. Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium. Weng LC, Lunetta KL, Müller-Nurasyid M, Smith AV, Thériault S, Weeke PE, Barnard J, Bis JC, Lyytikäinen LP, Kleber ME, Martinsson A, Lin HJ, Rienstra M, Trompet S, Krijthe BP, Dörr M, Klarin D, Chasman DI, Sinner MF, Waldenberger M, Launer LJ, Harris TB, Soliman EZ, Alonso A, Paré G, Teixeira PL, Denny JC, Shoemaker MB, Van Wagoner DR, Smith JD, Psaty BM, Sotoodehnia N, Taylor KD, Kähönen M, Nikus K, Delgado GE, Melander O, Engström G, Yao J, Guo X, Christophersen IE, Ellinor PT, Geelhoed B, Verweij N, Macfarlane P, Ford I, Heeringa J, Franco OH, Uitterlinden AG, Völker U, Teumer A, Rose LM, Kääb S, Gudnason V, Arking DE, Conen D, Roden DM, Chung MK, Heckbert SR, Benjamin EJ, Lehtimäki T, März W, Smith JG, Rotter JI, van der Harst P, Jukema JW, Stricker BH, Felix SB, Albert CM, Lubitz SA (2017) Sci Rep 7(1): 11303
    › Primary publication · 28900195 (PubMed) · PMC5595875 (PubMed Central)
  22. A multi-stage genome-wide association study of uterine fibroids in African Americans. Hellwege JN, Jeff JM, Wise LA, Gallagher CS, Wellons M, Hartmann KE, Jones SF, Torstenson ES, Dickinson S, Ruiz-Narváez EA, Rohland N, Allen A, Reich D, Tandon A, Pasaniuc B, Mancuso N, Im HK, Hinds DA, Palmer JR, Rosenberg L, Denny JC, Roden DM, Stewart EA, Morton CC, Kenny EE, Edwards TL, Velez Edwards DR (2017) Hum Genet 136(10): 1363-1373
    › Primary publication · 28836065 (PubMed) · PMC5628188 (PubMed Central)
  23. Identifying Metastases-related Information from Pathology Reports of Lung Cancer Patients. Soysal E, Warner JL, Denny JC, Xu H (2017) AMIA Jt Summits Transl Sci Proc : 268-277
    › Primary publication · 28815141 (PubMed) · PMC5543353 (PubMed Central)
  24. A comparison of rule-based and machine learning approaches for classifying patient portal messages. Cronin RM, Fabbri D, Denny JC, Rosenbloom ST, Jackson GP (2017) Int J Med Inform : 110-120
    › Primary publication · 28750904 (PubMed) · PMC5546247 (PubMed Central)
  25. Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, Low SK, Weeke PE, Müller-Nurasyid M, Smith JG, Brody JA, Niemeijer MN, Dörr M, Trompet S, Huffman J, Gustafsson S, Schurmann C, Kleber ME, Lyytikäinen LP, Seppälä I, Malik R, R V R Horimoto A, Perez M, Sinisalo J, Aeschbacher S, Thériault S, Yao J, Radmanesh F, Weiss S, Teumer A, Choi SH, Weng LC, Clauss S, Deo R, Rader DJ, Shah SH, Sun A, Hopewell JC, Debette S, Chauhan G, Yang Q, Worrall BB, Paré G, Kamatani Y, Hagemeijer YP, Verweij N, Siland JE, Kubo M, Smith JD, Van Wagoner DR, Bis JC, Perz S, Psaty BM, Ridker PM, Magnani JW, Harris TB, Launer LJ, Shoemaker MB, Padmanabhan S, Haessler J, Bartz TM, Waldenberger M, Lichtner P, Arendt M, Krieger JE, Kähönen M, Risch L, Mansur AJ, Peters A, Smith BH, Lind L, Scott SA, Lu Y, Bottinger EB, Hernesniemi J, Lindgren CM, Wong JA, Huang J, Eskola M, Morris AP, Ford I, Reiner AP, Delgado G, Chen LY, Chen YI, Sandhu RK, Li M, Boerwinkle E, Eisele L, Lannfelt L, Rost N, Anderson CD, Taylor KD, Campbell A, Magnusson PK, Porteous D, Hocking LJ, Vlachopoulou E, Pedersen NL, Nikus K, Orho-Melander M, Hamsten A, Heeringa J, Denny JC, Kriebel J, Darbar D, Newton-Cheh C, Shaffer C, Macfarlane PW, Heilmann-Heimbach S, Almgren P, Huang PL, Sotoodehnia N, Soliman EZ, Uitterlinden AG, Hofman A, Franco OH, Völker U, Jöckel KH, Sinner MF, Lin HJ, Guo X, METASTROKE Consortium of the ISGC, Neurology Working Group of the CHARGE Consortium, Dichgans M, Ingelsson E, Kooperberg C, Melander O, J F Loos R, Laurikka J, Conen D, Rosand J, van der Harst P, Lokki ML, Kathiresan S, Pereira A, Jukema JW, Hayward C, Rotter JI, März W, Lehtimäki T, Stricker BH, Chung MK, Felix SB, Gudnason V, Alonso A, Roden DM, Kääb S, Chasman DI, Heckbert SR, Benjamin EJ, Tanaka T, Lunetta KL, Lubitz SA, Ellinor PT, AFGen Consortium (2017) Nat Genet 49(8): 1286
    › Primary publication · 28747752 (PubMed)
  26. An active learning-enabled annotation system for clinical named entity recognition. Chen Y, Lask TA, Mei Q, Chen Q, Moon S, Wang J, Nguyen K, Dawodu T, Cohen T, Denny JC, Xu H (2017) BMC Med Inform Decis Mak 17(Suppl 2): 82
    › Primary publication · 28699546 (PubMed) · PMC5506567 (PubMed Central)
  27. Influence of Human Leukocyte Antigen (HLA) Alleles and Killer Cell Immunoglobulin-Like Receptors (KIR) Types on Heparin-Induced Thrombocytopenia (HIT). Karnes JH, Shaffer CM, Cronin R, Bastarache L, Gaudieri S, James I, Pavlos R, Steiner HE, Mosley JD, Mallal S, Denny JC, Phillips EJ, Roden DM (2017) Pharmacotherapy 37(9): 1164-1171
    › Primary publication · 28688202 (PubMed) · PMC5600645 (PubMed Central)
  28. Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record. Wei WQ, Bastarache LA, Carroll RJ, Marlo JE, Osterman TJ, Gamazon ER, Cox NJ, Roden DM, Denny JC (2017) PLoS One 12(7): e0175508
    › Primary publication · 28686612 (PubMed) · PMC5501393 (PubMed Central)
  29. A common deletion in the haptoglobin gene associated with blood cholesterol levels among Chinese women. Zheng NS, Bastarache LA, Bastarache JA, Lu Y, Ware LB, Shu XO, Denny JC, Long J (2017) J Hum Genet 62(10): 911-914
    › Primary publication · 28659611 (PubMed) · PMC5824713 (PubMed Central)
  30. Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults. Wells QS, Veatch OJ, Fessel JP, Joon AY, Levinson RT, Mosley JD, Held EP, Lindsay CS, Shaffer CM, Weeke PE, Glazer AM, Bersell KR, Van Driest SL, Karnes JH, Blair MA, Lagrone LW, Su YR, Bowton EA, Feng Z, Ky B, Lenihan DJ, Fisch MJ, Denny JC, Roden DM (2017) Pharmacogenet Genomics 27(7): 247-254
    › Primary publication · 28542097 (PubMed) · PMC5502740 (PubMed Central)
  31. Challenges and strategies for implementing genomic services in diverse settings: experiences from the Implementing GeNomics In pracTicE (IGNITE) network. Sperber NR, Carpenter JS, Cavallari LH, J Damschroder L, Cooper-DeHoff RM, Denny JC, Ginsburg GS, Guan Y, Horowitz CR, Levy KD, Levy MA, Madden EB, Matheny ME, Pollin TI, Pratt VM, Rosenman M, Voils CI, W Weitzel K, Wilke RA, Ryanne Wu R, Orlando LA (2017) BMC Med Genomics 10(1): 35
    › Primary publication · 28532511 (PubMed) · PMC5441047 (PubMed Central)
  32. Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations. Liang J, Le TH, Edwards DRV, Tayo BO, Gaulton KJ, Smith JA, Lu Y, Jensen RA, Chen G, Yanek LR, Schwander K, Tajuddin SM, Sofer T, Kim W, Kayima J, McKenzie CA, Fox E, Nalls MA, Young JH, Sun YV, Lane JM, Cechova S, Zhou J, Tang H, Fornage M, Musani SK, Wang H, Lee J, Adeyemo A, Dreisbach AW, Forrester T, Chu PL, Cappola A, Evans MK, Morrison AC, Martin LW, Wiggins KL, Hui Q, Zhao W, Jackson RD, Ware EB, Faul JD, Reiner AP, Bray M, Denny JC, Mosley TH, Palmas W, Guo X, Papanicolaou GJ, Penman AD, Polak JF, Rice K, Taylor KD, Boerwinkle E, Bottinger EP, Liu K, Risch N, Hunt SC, Kooperberg C, Zonderman AB, Laurie CC, Becker DM, Cai J, Loos RJF, Psaty BM, Weir DR, Kardia SLR, Arnett DK, Won S, Edwards TL, Redline S, Cooper RS, Rao DC, Rotter JI, Rotimi C, Levy D, Chakravarti A, Zhu X, Franceschini N (2017) PLoS Genet 13(5): e1006728
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  33. Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants. Karnes JH, Bastarache L, Shaffer CM, Gaudieri S, Xu Y, Glazer AM, Mosley JD, Zhao S, Raychaudhuri S, Mallal S, Ye Z, Mayer JG, Brilliant MH, Hebbring SJ, Roden DM, Phillips EJ, Denny JC (2017) Sci Transl Med 9(389)
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  34. Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, Low SK, Weeke PE, Müller-Nurasyid M, Smith JG, Brody JA, Niemeijer MN, Dörr M, Trompet S, Huffman J, Gustafsson S, Schurmann C, Kleber ME, Lyytikäinen LP, Seppälä I, Malik R, Horimoto ARVR, Perez M, Sinisalo J, Aeschbacher S, Thériault S, Yao J, Radmanesh F, Weiss S, Teumer A, Choi SH, Weng LC, Clauss S, Deo R, Rader DJ, Shah SH, Sun A, Hopewell JC, Debette S, Chauhan G, Yang Q, Worrall BB, Paré G, Kamatani Y, Hagemeijer YP, Verweij N, Siland JE, Kubo M, Smith JD, Van Wagoner DR, Bis JC, Perz S, Psaty BM, Ridker PM, Magnani JW, Harris TB, Launer LJ, Shoemaker MB, Padmanabhan S, Haessler J, Bartz TM, Waldenberger M, Lichtner P, Arendt M, Krieger JE, Kähönen M, Risch L, Mansur AJ, Peters A, Smith BH, Lind L, Scott SA, Lu Y, Bottinger EB, Hernesniemi J, Lindgren CM, Wong JA, Huang J, Eskola M, Morris AP, Ford I, Reiner AP, Delgado G, Chen LY, Chen YI, Sandhu RK, Li M, Boerwinkle E, Eisele L, Lannfelt L, Rost N, Anderson CD, Taylor KD, Campbell A, Magnusson PK, Porteous D, Hocking LJ, Vlachopoulou E, Pedersen NL, Nikus K, Orho-Melander M, Hamsten A, Heeringa J, Denny JC, Kriebel J, Darbar D, Newton-Cheh C, Shaffer C, Macfarlane PW, Heilmann-Heimbach S, Almgren P, Huang PL, Sotoodehnia N, Soliman EZ, Uitterlinden AG, Hofman A, Franco OH, Völker U, Jöckel KH, Sinner MF, Lin HJ, Guo X, METASTROKE Consortium of the ISGC, Neurology Working Group of the CHARGE Consortium, Dichgans M, Ingelsson E, Kooperberg C, Melander O, Loos RJF, Laurikka J, Conen D, Rosand J, van der Harst P, Lokki ML, Kathiresan S, Pereira A, Jukema JW, Hayward C, Rotter JI, März W, Lehtimäki T, Stricker BH, Chung MK, Felix SB, Gudnason V, Alonso A, Roden DM, Kääb S, Chasman DI, Heckbert SR, Benjamin EJ, Tanaka T, Lunetta KL, Lubitz SA, Ellinor PT, AFGen Consortium (2017) Nat Genet 49(6): 946-952
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  35. Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes. Mosley JD, Shoemaker MB, Wells QS, Darbar D, Shaffer CM, Edwards TL, Bastarache L, McCarty CA, Thompson W, Chute CG, Jarvik GP, Crosslin DR, Larson EB, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Witte JS, Denny JC, Roden DM (2017) Circ Cardiovasc Genet 10(2)
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  36. Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics. Pulley JM, Shirey-Rice JK, Lavieri RR, Jerome RN, Zaleski NM, Aronoff DM, Bastarache L, Niu X, Holroyd KJ, Roden DM, Skaar EP, Niswender CM, Marnett LJ, Lindsley CW, Ekstrom LB, Bentley AR, Bernard GR, Hong CC, Denny JC (2017) Assay Drug Dev Technol 15(3): 113-119
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  37. Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans. Nadkarni GN, Galarneau G, Ellis SB, Nadukuru R, Zhang J, Scott SA, Schurmann C, Li R, Rasmussen-Torvik LJ, Kho AN, Hayes MG, Pacheco JA, Manolio TA, Chisholm RL, Roden DM, Denny JC, Kenny EE, Bottinger EP (2017) J Am Coll Cardiol 69(12): 1564-1574
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  38. An Empirical Study for Impacts of Measurement Errors on EHR based Association Studies. Duan R, Cao M, Wu Y, Huang J, Denny JC, Xu H, Chen Y (2016) AMIA Annu Symp Proc : 1764-1773
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  39. Genome-wide study of resistant hypertension identified from electronic health records. Dumitrescu L, Ritchie MD, Denny JC, El Rouby NM, McDonough CW, Bradford Y, Ramirez AH, Bielinski SJ, Basford MA, Chai HS, Peissig P, Carrell D, Pathak J, Rasmussen LV, Wang X, Pacheco JA, Kho AN, Hayes MG, Matsumoto M, Smith ME, Li R, Cooper-DeHoff RM, Kullo IJ, Chute CG, Chisholm RL, Jarvik GP, Larson EB, Carey D, McCarty CA, Williams MS, Roden DM, Bottinger E, Johnson JA, de Andrade M, Crawford DC (2017) PLoS One 12(2): e0171745
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  40. Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. Webb TR, Erdmann J, Stirrups KE, Stitziel NO, Masca NG, Jansen H, Kanoni S, Nelson CP, Ferrario PG, König IR, Eicher JD, Johnson AD, Hamby SE, Betsholtz C, Ruusalepp A, Franzén O, Schadt EE, Björkegren JL, Weeke PE, Auer PL, Schick UM, Lu Y, Zhang H, Dube MP, Goel A, Farrall M, Peloso GM, Won HH, Do R, van Iperen E, Kruppa J, Mahajan A, Scott RA, Willenborg C, Braund PS, van Capelleveen JC, Doney AS, Donnelly LA, Asselta R, Merlini PA, Duga S, Marziliano N, Denny JC, Shaffer C, El-Mokhtari NE, Franke A, Heilmann S, Hengstenberg C, Hoffmann P, Holmen OL, Hveem K, Jansson JH, Jöckel KH, Kessler T, Kriebel J, Laugwitz KL, Marouli E, Martinelli N, McCarthy MI, Van Zuydam NR, Meisinger C, Esko T, Mihailov E, Escher SA, Alver M, Moebus S, Morris AD, Virtamo J, Nikpay M, Olivieri O, Provost S, AlQarawi A, Robertson NR, Akinsansya KO, Reilly DF, Vogt TF, Yin W, Asselbergs FW, Kooperberg C, Jackson RD, Stahl E, Müller-Nurasyid M, Strauch K, Varga TV, Waldenberger M, Wellcome Trust Case Control Consortium, Zeng L, Chowdhury R, Salomaa V, Ford I, Jukema JW, Amouyel P, Kontto J, MORGAM Investigators, Nordestgaard BG, Ferrières J, Saleheen D, Sattar N, Surendran P, Wagner A, Young R, Howson JM, Butterworth AS, Danesh J, Ardissino D, Bottinger EP, Erbel R, Franks PW, Girelli D, Hall AS, Hovingh GK, Kastrati A, Lieb W, Meitinger T, Kraus WE, Shah SH, McPherson R, Orho-Melander M, Melander O, Metspalu A, Palmer CN, Peters A, Rader DJ, Reilly MP, Loos RJ, Reiner AP, Roden DM, Tardif JC, Thompson JR, Wareham NJ, Watkins H, Willer CJ, Samani NJ, Schunkert H, Deloukas P, Kathiresan S, Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators (2017) J Am Coll Cardiol 69(7): 823-836
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  41. Comparison of HLA allelic imputation programs. Karnes JH, Shaffer CM, Bastarache L, Gaudieri S, Glazer AM, Steiner HE, Mosley JD, Mallal S, Denny JC, Phillips EJ, Roden DM (2017) PLoS One 12(2): e0172444
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  42. Identification of unique venous thromboembolism-susceptibility variants in African-Americans. Heit JA, Armasu SM, McCauley BM, Kullo IJ, Sicotte H, Pathak J, Chute CG, Gottesman O, Bottinger EP, Denny JC, Roden DM, Li R, Ritchie MD, de Andrade M (2017) Thromb Haemost 117(4): 758-768
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  43. Effects of deletion on body weight and cholesterol in mice. Boortz KA, Syring KE, Pound LD, Mo H, Bastarache L, Oeser JK, McGuinness OP, Denny JC, O'Brien RM (2017) J Mol Endocrinol 58(3): 127-139
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  44. and Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C, Gorski M, Lyytikäinen LP, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, Ahluwalia TS, Arking DE, Bihlmeyer NA, Böger CA, Carroll RJ, Chasman DI, Cornelis MC, Dehghan A, Faul JD, Feitosa MF, Gambaro G, Gasparini P, Giulianini F, Heid I, Huang J, Imboden M, Jackson AU, Jeff J, Jhun MA, Katz R, Kifley A, Kilpeläinen TO, Kumar A, Laakso M, Li-Gao R, Lohman K, Lu Y, Mägi R, Malerba G, Mihailov E, Mohlke KL, Mook-Kanamori DO, Robino A, Ruderfer D, Salvi E, Schick UM, Schulz CA, Smith AV, Smith JA, Traglia M, Yerges-Armstrong LM, Zhao W, Goodarzi MO, Kraja AT, Liu C, Wessel J, CHARGE Glycemic-T2D Working Group,, CHARGE Blood Pressure Working Group,, Boerwinkle E, Borecki IB, Bork-Jensen J, Bottinger EP, Braga D, Brandslund I, Brody JA, Campbell A, Carey DJ, Christensen C, Coresh J, Crook E, Curhan GC, Cusi D, de Boer IH, de Vries AP, Denny JC, Devuyst O, Dreisbach AW, Endlich K, Esko T, Franco OH, Fulop T, Gerhard GS, Glümer C, Gottesman O, Grarup N, Gudnason V, Hansen T, Harris TB, Hayward C, Hocking L, Hofman A, Hu FB, Husemoen LL, Jackson RD, Jørgensen T, Jørgensen ME, Kähönen M, Kardia SL, König W, Kooperberg C, Kriebel J, Launer LJ, Lauritzen T, Lehtimäki T, Levy D, Linksted P, Linneberg A, Liu Y, Loos RJ, Lupo A, Meisinger C, Melander O, Metspalu A, Mitchell P, Nauck M, Nürnberg P, Orho-Melander M, Parsa A, Pedersen O, Peters A, Peters U, Polasek O, Porteous D, Probst-Hensch NM, Psaty BM, Qi L, Raitakari OT, Reiner AP, Rettig R, Ridker PM, Rivadeneira F, Rossouw JE, Schmidt F, Siscovick D, Soranzo N, Strauch K, Toniolo D, Turner ST, Uitterlinden AG, Ulivi S, Velayutham D, Völker U, Völzke H, Waldenberger M, Wang JJ, Weir DR, Witte D, Kuivaniemi H, Fox CS, Franceschini N, Goessling W, Köttgen A, Chu AY (2017) J Am Soc Nephrol 28(3): 981-994
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  45. PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study. Schmidt AF, Swerdlow DI, Holmes MV, Patel RS, Fairhurst-Hunter Z, Lyall DM, Hartwig FP, Horta BL, Hyppönen E, Power C, Moldovan M, van Iperen E, Hovingh GK, Demuth I, Norman K, Steinhagen-Thiessen E, Demuth J, Bertram L, Liu T, Coassin S, Willeit J, Kiechl S, Willeit K, Mason D, Wright J, Morris R, Wanamethee G, Whincup P, Ben-Shlomo Y, McLachlan S, Price JF, Kivimaki M, Welch C, Sanchez-Galvez A, Marques-Vidal P, Nicolaides A, Panayiotou AG, Onland-Moret NC, van der Schouw YT, Matullo G, Fiorito G, Guarrera S, Sacerdote C, Wareham NJ, Langenberg C, Scott R, Luan J, Bobak M, Malyutina S, Pająk A, Kubinova R, Tamosiunas A, Pikhart H, Husemoen LL, Grarup N, Pedersen O, Hansen T, Linneberg A, Simonsen KS, Cooper J, Humphries SE, Brilliant M, Kitchner T, Hakonarson H, Carrell DS, McCarty CA, Kirchner HL, Larson EB, Crosslin DR, de Andrade M, Roden DM, Denny JC, Carty C, Hancock S, Attia J, Holliday E, O'Donnell M, Yusuf S, Chong M, Pare G, van der Harst P, Said MA, Eppinga RN, Verweij N, Snieder H, LifeLines Cohort study group, Christen T, Mook-Kanamori DO, Gustafsson S, Lind L, Ingelsson E, Pazoki R, Franco O, Hofman A, Uitterlinden A, Dehghan A, Teumer A, Baumeister S, Dörr M, Lerch MM, Völker U, Völzke H, Ward J, Pell JP, Smith DJ, Meade T, Maitland-van der Zee AH, Baranova EV, Young R, Ford I, Campbell A, Padmanabhan S, Bots ML, Grobbee DE, Froguel P, Thuillier D, Balkau B, Bonnefond A, Cariou B, Smart M, Bao Y, Kumari M, Mahajan A, Ridker PM, Chasman DI, Reiner AP, Lange LA, Ritchie MD, Asselbergs FW, Casas JP, Keating BJ, Preiss D, Hingorani AD, UCLEB consortium, Sattar N (2017) Lancet Diabetes Endocrinol 5(2): 97-105
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  46. STRATEGIES FOR EQUITABLE PHARMACOGENOMIC-GUIDED WARFARIN DOSING AMONG EUROPEAN AND AFRICAN AMERICAN INDIVIDUALS IN A CLINICAL POPULATION. Wiley LK, Vanhouten JP, Samuels DC, Aldrich MC, Roden DM, Peterson JF, Denny JC (2017) Pac Symp Biocomput : 545-556
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  47. PRECISION MEDICINE: DATA AND DISCOVERY FOR IMPROVED HEALTH AND THERAPY. Morgan AA, Crawford DC, Denny JC, Mooney SD, Aronow BJ, Brenner SE (2017) Pac Symp Biocomput : 348-355
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  48. On the Potential of Preemptive Genotyping Towards Preventing Medication-Related Adverse Events: Results from the South Korean National Health Insurance Database. Schildcrout JS, Denny JC, Roden DM (2017) Drug Saf 40(1): 1-2
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  49. Reply. Doss J, Mo H, Carroll RJ, Crofford LJ, Denny JC (2017) Arthritis Rheumatol 69(3): 680-681
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  50. Performance of an electronic health record-based phenotype algorithm to identify community associated methicillin-resistant Staphylococcus aureus cases and controls for genetic association studies. Jackson KL, Mbagwu M, Pacheco JA, Baldridge AS, Viox DJ, Linneman JG, Shukla SK, Peissig PL, Borthwick KM, Carrell DA, Bielinski SJ, Kirby JC, Denny JC, Mentch FD, Vazquez LM, Rasmussen-Torvik LJ, Kho AN (2016) BMC Infect Dis 16(1): 684
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  51. Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data. Mosley JD, van Driest SL, Wells QS, Shaffer CM, Edwards TL, Bastarache L, McCarty CA, Thompson W, Chute CG, Jarvik GP, Crosslin DR, Larson EB, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Denny JC, Roden DM (2016) Circ Cardiovasc Genet 9(6): 521-530
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  52. Transcription factor ETV1 is essential for rapid conduction in the heart. Shekhar A, Lin X, Liu FY, Zhang J, Mo H, Bastarache L, Denny JC, Cox NJ, Delmar M, Roden DM, Fishman GI, Park DS (2016) J Clin Invest 126(12): 4444-4459
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  53. Finding a Needle in a QT Interval Big Data Haystack: The Role for Orthogonal Datasets. Roden DM, Mosley JD, Denny JC (2016) J Am Coll Cardiol 68(16): 1765-1768
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  54. Evaluation of a Prediction Model for the Development of Atrial Fibrillation in a Repository of Electronic Medical Records. Kolek MJ, Graves AJ, Xu M, Bian A, Teixeira PL, Shoemaker MB, Parvez B, Xu H, Heckbert SR, Ellinor PT, Benjamin EJ, Alonso A, Denny JC, Moons KG, Shintani AK, Harrell FE, Roden DM, Darbar D (2016) JAMA Cardiol 1(9): 1007-1013
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  55. Practical considerations for implementing genomic information resources. Experiences from eMERGE and CSER. Rasmussen LV, Overby CL, Connolly J, Chute CG, Denny JC, Freimuth R, Hartzler AL, Holm IA, Manzi S, Pathak J, Peissig PL, Smith M, Williams MS, Shirts BH, Stoffel EM, Tarczy-Hornoch P, Rohrer Vitek CR, Wolf WA, Starren J (2016) Appl Clin Inform 7(3): 870-82
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  56. Population-specific single-nucleotide polymorphism confers increased risk of venous thromboembolism in African Americans. Daneshjou R, Cavallari LH, Weeke PE, Karczewski KJ, Drozda K, Perera MA, Johnson JA, Klein TE, Bustamante CD, Roden DM, Shaffer C, Denny JC, Zehnder JL, Altman RB (2016) Mol Genet Genomic Med 4(5): 513-20
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  57. Genetic determinants of variability in warfarin response after the dose-titration phase. Iwuchukwu OF, Ramirez AH, Shi Y, Bowton EA, Kawai VK, Schildcrout JS, Roden DM, Denny JC, Stein CM (2016) Pharmacogenet Genomics 26(11): 510-516
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  58. Phenome-Wide Association Study of Rheumatoid Arthritis Subgroups Identifies Association Between Seronegative Disease and Fibromyalgia. Doss J, Mo H, Carroll RJ, Crofford LJ, Denny JC (2017) Arthritis Rheumatol 69(2): 291-300
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  59. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE, Deshmukh HA, Evans DS, Feng Q, Li X, Smit RA, Smith AV, Sun F, Taylor KD, Arnold AM, Barnes MR, Barratt BJ, Betteridge J, Boekholdt SM, Boerwinkle E, Buckley BM, Chen YI, de Craen AJ, Cummings SR, Denny JC, Dubé MP, Durrington PN, Eiriksdottir G, Ford I, Guo X, Harris TB, Heckbert SR, Hofman A, Hovingh GK, Kastelein JJ, Launer LJ, Liu CT, Liu Y, Lumley T, McKeigue PM, Munroe PB, Neil A, Nickerson DA, Nyberg F, O'Brien E, O'Donnell CJ, Post W, Poulter N, Vasan RS, Rice K, Rich SS, Rivadeneira F, Sattar N, Sever P, Shaw-Hawkins S, Shields DC, Slagboom PE, Smith NL, Smith JD, Sotoodehnia N, Stanton A, Stott DJ, Stricker BH, Stürmer T, Uitterlinden AG, Wei WQ, Westendorp RG, Whitsel EA, Wiggins KL, Wilke RA, Ballantyne CM, Colhoun HM, Cupples LA, Franco OH, Gudnason V, Hitman G, Palmer CN, Psaty BM, Ridker PM, Stafford JM, Stein CM, Tardif JC, Caulfield MJ, Jukema JW, Rotter JI, Krauss RM (2016) J Med Genet 53(12): 835-845
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  60. A Decompositional Approach to Executing Quality Data Model Algorithms on the i2b2 Platform. Mo H, Jiang G, Pacheco JA, Kiefer R, Rasmussen LV, Pathak J, Denny JC, Thompson WK (2016) AMIA Jt Summits Transl Sci Proc : 167-75
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  61. A long journey to short abbreviations: developing an open-source framework for clinical abbreviation recognition and disambiguation (CARD). Wu Y, Denny JC, Trent Rosenbloom S, Miller RA, Giuse DA, Wang L, Blanquicett C, Soysal E, Xu J, Xu H (2017) J Am Med Inform Assoc 24(e1): e79-e86
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  62. eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants. Verma A, Verma SS, Pendergrass SA, Crawford DC, Crosslin DR, Kuivaniemi H, Bush WS, Bradford Y, Kullo I, Bielinski SJ, Li R, Denny JC, Peissig P, Hebbring S, De Andrade M, Ritchie MD, Tromp G (2016) BMC Med Genomics : 32
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  63. Clinical phenotyping in selected national networks: demonstrating the need for high-throughput, portable, and computational methods. Richesson RL, Sun J, Pathak J, Kho AN, Denny JC (2016) Artif Intell Med : 57-61
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  64. Evaluating electronic health record data sources and algorithmic approaches to identify hypertensive individuals. Teixeira PL, Wei WQ, Cronin RM, Mo H, VanHouten JP, Carroll RJ, LaRose E, Bastarache LA, Rosenbloom ST, Edwards TL, Roden DM, Lasko TA, Dart RA, Nikolai AM, Peissig PL, Denny JC (2017) J Am Med Inform Assoc 24(1): 162-171
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  65. Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions. Li H, Achour I, Bastarache L, Berghout J, Gardeux V, Li J, Lee Y, Pesce L, Yang X, Ramos KS, Foster I, Denny JC, Moore JH, Lussier YA (2016) NPJ Genom Med
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  66. Developing a data element repository to support EHR-driven phenotype algorithm authoring and execution. Jiang G, Kiefer RC, Rasmussen LV, Solbrig HR, Mo H, Pacheco JA, Xu J, Montague E, Thompson WK, Denny JC, Chute CG, Pathak J (2016) J Biomed Inform : 232-42
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  67. Developing Electronic Health Record Algorithms That Accurately Identify Patients With Systemic Lupus Erythematosus. Barnado A, Casey C, Carroll RJ, Wheless L, Denny JC, Crofford LJ (2017) Arthritis Care Res (Hoboken) 69(5): 687-693
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  185. Assessment of a pharmacogenomic marker panel in a polypharmacy population identified from electronic medical records. Oetjens MT, Denny JC, Ritchie MD, Gillani NB, Richardson DM, Restrepo NA, Pulley JM, Dilks HH, Basford MA, Bowton E, Masys DR, Wilke RA, Roden DM, Crawford DC (2013) Pharmacogenomics 14(7): 735-44
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  186. Development and evaluation of an ensemble resource linking medications to their indications. Wei WQ, Cronin RM, Xu H, Lasko TA, Bastarache L, Denny JC (2013) J Am Med Inform Assoc 20(5): 954-61
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  187. A hybrid system for temporal information extraction from clinical text. Tang B, Wu Y, Jiang M, Chen Y, Denny JC, Xu H (2013) J Am Med Inform Assoc 20(5): 828-35
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  188. Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans. Jeff JM, Ritchie MD, Denny JC, Kho AN, Ramirez AH, Crosslin D, Armstrong L, Basford MA, Wolf WA, Pacheco JA, Chisholm RL, Roden DM, Hayes MG, Crawford DC (2013) Ann Hum Genet 77(4): 321-32
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  189. Validation of electronic medical record-based phenotyping algorithms: results and lessons learned from the eMERGE network. Newton KM, Peissig PL, Kho AN, Bielinski SJ, Berg RL, Choudhary V, Basford M, Chute CG, Kullo IJ, Li R, Pacheco JA, Rasmussen LV, Spangler L, Denny JC (2013) J Am Med Inform Assoc 20(e1): e147-54
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  190. Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosley JD, Pulley JM, Basford MA, Bradford Y, Rasmussen LV, Pathak J, Chute CG, Kullo IJ, McCarty CA, Chisholm RL, Kho AN, Carlson CS, Larson EB, Jarvik GP, Sotoodehnia N, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) QRS Group, Manolio TA, Li R, Masys DR, Haines JL, Roden DM (2013) Circulation 127(13): 1377-85
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  191. The effect of reducing maximum shift lengths to 16 hours on internal medicine interns' educational opportunities. Theobald CN, Stover DG, Choma NN, Hathaway J, Green JK, Peterson NB, Sponsler KC, Vasilevskis EE, Kripalani S, Sergent J, Brown NJ, Denny JC (2013) Acad Med 88(4): 512-8
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  192. Enabling genomic-phenomic association discovery without sacrificing anonymity. Heatherly RD, Loukides G, Denny JC, Haines JL, Roden DM, Malin BA (2013) PLoS One 8(2): e53875
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  193. A comparative study of current Clinical Natural Language Processing systems on handling abbreviations in discharge summaries. Wu Y, Denny JC, Rosenbloom ST, Miller RA, Giuse DA, Xu H (2012) AMIA Annu Symp Proc : 997-1003
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  194. An evaluation of the NQF Quality Data Model for representing Electronic Health Record driven phenotyping algorithms. Thompson WK, Rasmussen LV, Pacheco JA, Peissig PL, Denny JC, Kho AN, Miller A, Pathak J (2012) AMIA Annu Symp Proc : 911-20
    › Primary publication · 23304366 (PubMed) · PMC3540514 (PubMed Central)
  195. A study of transportability of an existing smoking status detection module across institutions. Liu M, Shah A, Jiang M, Peterson NB, Dai Q, Aldrich MC, Chen Q, Bowton EA, Liu H, Denny JC, Xu H (2012) AMIA Annu Symp Proc : 577-86
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  196. Extracting semantic lexicons from discharge summaries using machine learning and the C-Value method. Jiang M, Denny JC, Tang B, Cao H, Xu H (2012) AMIA Annu Symp Proc : 409-16
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  197. Chapter 13: Mining electronic health records in the genomics era. Denny JC (2012) PLoS Comput Biol 8(12): e1002823
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  198. Response to "Doubt about the feasibility of preemptive genotyping". Denny JC, Schildcrout JS, Pulley JM, Roden DM (2013) Clin Pharmacol Ther 93(3): 234
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  199. Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls. Liao KP, Kurreeman F, Li G, Duclos G, Murphy S, Guzman R, Cai T, Gupta N, Gainer V, Schur P, Cui J, Denny JC, Szolovits P, Churchill S, Kohane I, Karlson EW, Plenge RM (2013) Arthritis Rheum 65(3): 571-81
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  200. Mapping the incidentalome: estimating incidental findings generated through clinical pharmacogenomics testing. Westbrook MJ, Wright MF, Van Driest SL, McGregor TL, Denny JC, Zuvich RL, Clayton EW, Brothers KB (2013) Genet Med 15(5): 325-31
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  201. Comparative analysis of pharmacovigilance methods in the detection of adverse drug reactions using electronic medical records. Liu M, McPeek Hinz ER, Matheny ME, Denny JC, Schildcrout JS, Miller RA, Xu H (2013) J Am Med Inform Assoc 20(3): 420-6
    › Primary publication · 23161894 (PubMed) · PMC3628053 (PubMed Central)
  202. Extracting epidemiologic exposure and outcome terms from literature using machine learning approaches. Lu Y, Xu H, Peterson NB, Dai Q, Jiang M, Denny JC, Liu M (2012) Int J Data Min Bioinform 6(4): 447-59
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  203. High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE. Rasmussen-Torvik LJ, Pacheco JA, Wilke RA, Thompson WK, Ritchie MD, Kho AN, Muthalagu A, Hayes MG, Armstrong LL, Scheftner DA, Wilkins JT, Zuvich RL, Crosslin D, Roden DM, Denny JC, Jarvik GP, Carlson CS, Kullo IJ, Bielinski SJ, McCarty CA, Li R, Manolio TA, Crawford DC, Chisholm RL (2012) Clin Transl Sci 5(5): 394-9
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  204. Optimizing drug outcomes through pharmacogenetics: a case for preemptive genotyping. Schildcrout JS, Denny JC, Bowton E, Gregg W, Pulley JM, Basford MA, Cowan JD, Xu H, Ramirez AH, Crawford DC, Ritchie MD, Peterson JF, Masys DR, Wilke RA, Roden DM (2012) Clin Pharmacol Ther 92(2): 235-42
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  205. Detecting temporal expressions in medical narratives. Reeves RM, Ong FR, Matheny ME, Denny JC, Aronsky D, Gobbel GT, Montella D, Speroff T, Brown SH (2013) Int J Med Inform 82(2): 118-27
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  206. Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project. Pulley JM, Denny JC, Peterson JF, Bernard GR, Vnencak-Jones CL, Ramirez AH, Delaney JT, Bowton E, Brothers K, Johnson K, Crawford DC, Schildcrout J, Masys DR, Dilks HH, Wilke RA, Clayton EW, Shultz E, Laposata M, McPherson J, Jirjis JN, Roden DM (2012) Clin Pharmacol Ther 92(1): 87-95
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  207. Electronic medical records as a tool in clinical pharmacology: opportunities and challenges. Roden DM, Xu H, Denny JC, Wilke RA (2012) Clin Pharmacol Ther 91(6): 1083-86
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  208. Portability of an algorithm to identify rheumatoid arthritis in electronic health records. Carroll RJ, Thompson WK, Eyler AE, Mandelin AM, Cai T, Zink RM, Pacheco JA, Boomershine CS, Lasko TA, Xu H, Karlson EW, Perez RG, Gainer VS, Murphy SN, Ruderman EM, Pope RM, Plenge RM, Kho AN, Liao KP, Denny JC (2012) J Am Med Inform Assoc 19(e1): e162-9
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  209. Return of individual research results from genome-wide association studies: experience of the Electronic Medical Records and Genomics (eMERGE) Network. Fullerton SM, Wolf WA, Brothers KB, Clayton EW, Crawford DC, Denny JC, Greenland P, Koenig BA, Leppig KA, Lindor NM, McCarty CA, McGuire AL, McPeek Hinz ER, Mirel DB, Ramos EM, Ritchie MD, Smith ME, Waudby CJ, Burke W, Jarvik GP (2012) Genet Med 14(4): 424-31
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  210. Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record. Ramirez AH, Shi Y, Schildcrout JS, Delaney JT, Xu H, Oetjens MT, Zuvich RL, Basford MA, Bowton E, Jiang M, Speltz P, Zink R, Cowan J, Pulley JM, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC (2012) Pharmacogenomics 13(4): 407-18
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  211. Importance of multi-modal approaches to effectively identify cataract cases from electronic health records. Peissig PL, Rasmussen LV, Berg RL, Linneman JG, McCarty CA, Waudby C, Chen L, Denny JC, Wilke RA, Pathak J, Carrell D, Kho AN, Starren JB (2012) J Am Med Inform Assoc 19(2): 225-34
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  212. Extracting and integrating data from entire electronic health records for detecting colorectal cancer cases. Xu H, Fu Z, Shah A, Chen Y, Peterson NB, Chen Q, Mani S, Levy MA, Dai Q, Denny JC (2011) AMIA Annu Symp Proc : 1564-72
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  213. Detecting abbreviations in discharge summaries using machine learning methods. Wu Y, Rosenbloom ST, Denny JC, Miller RA, Mani S, Giuse DA, Xu H (2011) AMIA Annu Symp Proc : 1541-9
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  214. Modeling drug exposure data in electronic medical records: an application to warfarin. Liu M, Jiang M, Kawai VK, Stein CM, Roden DM, Denny JC, Xu H (2011) AMIA Annu Symp Proc : 815-23
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  215. Analyzing the heterogeneity and complexity of Electronic Health Record oriented phenotyping algorithms. Conway M, Berg RL, Carrell D, Denny JC, Kho AN, Kullo IJ, Linneman JG, Pacheco JA, Peissig P, Rasmussen L, Weston N, Chute CG, Pathak J (2011) AMIA Annu Symp Proc : 274-83
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  216. Naïve Electronic Health Record phenotype identification for Rheumatoid arthritis. Carroll RJ, Eyler AE, Denny JC (2011) AMIA Annu Symp Proc : 189-96
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  217. Predicting clopidogrel response using DNA samples linked to an electronic health record. Delaney JT, Ramirez AH, Bowton E, Pulley JM, Basford MA, Schildcrout JS, Shi Y, Zink R, Oetjens M, Xu H, Cleator JH, Jahangir E, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC (2012) Clin Pharmacol Ther 91(2): 257-63
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  218. The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients. Birdwell KA, Grady B, Choi L, Xu H, Bian A, Denny JC, Jiang M, Vranic G, Basford M, Cowan JD, Richardson DM, Robinson MP, Ikizler TA, Ritchie MD, Stein CM, Haas DW (2012) Pharmacogenet Genomics 22(1): 32-42
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  219. Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study. Kho AN, Hayes MG, Rasmussen-Torvik L, Pacheco JA, Thompson WK, Armstrong LL, Denny JC, Peissig PL, Miller AW, Wei WQ, Bielinski SJ, Chute CG, Leibson CL, Jarvik GP, Crosslin DR, Carlson CS, Newton KM, Wolf WA, Chisholm RL, Lowe WL (2012) J Am Med Inform Assoc 19(2): 212-8
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  220. PASTE: patient-centered SMS text tagging in a medication management system. Stenner SP, Johnson KB, Denny JC (2012) J Am Med Inform Assoc 19(3): 368-74
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  221. Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. Denny JC, Crawford DC, Ritchie MD, Bielinski SJ, Basford MA, Bradford Y, Chai HS, Bastarache L, Zuvich R, Peissig P, Carrell D, Ramirez AH, Pathak J, Wilke RA, Rasmussen L, Wang X, Pacheco JA, Kho AN, Hayes MG, Weston N, Matsumoto M, Kopp PA, Newton KM, Jarvik GP, Li R, Manolio TA, Kullo IJ, Chute CG, Chisholm RL, Larson EB, McCarty CA, Masys DR, Roden DM, de Andrade M (2011) Am J Hum Genet 89(4): 529-42
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  222. Analyses of longitudinal, hospital clinical laboratory data with application to blood glucose concentrations. Schildcrout JS, Haneuse S, Peterson JF, Denny JC, Matheny ME, Waitman LR, Miller RA (2011) Stat Med 30(27): 3208-20
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  223. Applying semantic-based probabilistic context-free grammar to medical language processing--a preliminary study on parsing medication sentences. Xu H, AbdelRahman S, Lu Y, Denny JC, Doan S (2011) J Biomed Inform 44(6): 1068-75
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  224. Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate. Kullo IJ, Ding K, Shameer K, McCarty CA, Jarvik GP, Denny JC, Ritchie MD, Ye Z, Crosslin DR, Chisholm RL, Manolio TA, Chute CG (2011) Am J Hum Genet 89(1): 131-8
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  225. Facilitating pharmacogenetic studies using electronic health records and natural-language processing: a case study of warfarin. Xu H, Jiang M, Oetjens M, Bowton EA, Ramirez AH, Jeff JM, Basford MA, Pulley JM, Cowan JD, Wang X, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC (2011) J Am Med Inform Assoc 18(4): 387-91
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  226. Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels. Tatonetti NP, Denny JC, Murphy SN, Fernald GH, Krishnan G, Castro V, Yue P, Tsao PS, Tsau PS, Kohane I, Roden DM, Altman RB (2011) Clin Pharmacol Ther 90(1): 133-42
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  227. Teaching evidence-based medicine: Impact on students' literature use and inpatient clinical documentation. Sastre EA, Denny JC, McCoy JA, McCoy AB, Spickard A (2011) Med Teach 33(6): e306-12
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  228. Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks. Turner SD, Berg RL, Linneman JG, Peissig PL, Crawford DC, Denny JC, Roden DM, McCarty CA, Ritchie MD, Wilke RA (2011) PLoS One 6(5): e19586
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  229. A study of machine-learning-based approaches to extract clinical entities and their assertions from discharge summaries. Jiang M, Chen Y, Liu M, Rosenbloom ST, Mani S, Denny JC, Xu H (2011) J Am Med Inform Assoc 18(5): 601-6
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  230. Electronic medical records for genetic research: results of the eMERGE consortium. Kho AN, Pacheco JA, Peissig PL, Rasmussen L, Newton KM, Weston N, Crane PK, Pathak J, Chute CG, Bielinski SJ, Kullo IJ, Li R, Manolio TA, Chisholm RL, Denny JC (2011) Sci Transl Med 3(79): 79re1
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  231. Natural language processing improves identification of colorectal cancer testing in the electronic medical record. Denny JC, Choma NN, Peterson JF, Miller RA, Bastarache L, Li M, Peterson NB (2012) Med Decis Making 32(1): 188-97
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  232. An automated approach to calculating the daily dose of tacrolimus in electronic health records. Xu H, Doan S, Birdwell KA, Cowan JD, Vincz AJ, Haas DW, Basford MA, Denny JC (2010) Summit Transl Bioinform : 71-5
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  233. Mining Biomedical Literature for Terms related to Epidemiologic Exposures. Xu H, Lu Y, Jiang M, Liu M, Denny JC, Dai Q, Peterson NB (2010) AMIA Annu Symp Proc : 897-901
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  234. Anonymization of administrative billing codes with repeated diagnoses through censoring. Tamersoy A, Loukides G, Denny JC, Malin B (2010) AMIA Annu Symp Proc : 782-6
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  235. Prevalence and Clinical Significance of Discrepancies within Three Computerized Pre-Admission Medication Lists. Peterson JF, Shi Y, Denny JC, Matheny ME, Schildcrout JS, Waitman LR, Miller RA (2010) AMIA Annu Symp Proc : 642-6
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  236. Comparing content coverage in medical curriculum to trainee-authored clinical notes. Denny JC, Speltz P, Maddox R, Stein G, Xu H, Spickard A (2010) AMIA Annu Symp Proc : 157-61
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  237. The emerging role of electronic medical records in pharmacogenomics. Wilke RA, Xu H, Denny JC, Roden DM, Krauss RM, McCarty CA, Davis RL, Skaar T, Lamba J, Savova G (2011) Clin Pharmacol Ther 89(3): 379-86
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  238. Data from clinical notes: a perspective on the tension between structure and flexible documentation. Rosenbloom ST, Denny JC, Xu H, Lorenzi N, Stead WW, Johnson KB (2011) J Am Med Inform Assoc 18(2): 181-6
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  239. Modulators of normal electrocardiographic intervals identified in a large electronic medical record. Ramirez AH, Schildcrout JS, Blakemore DL, Masys DR, Pulley JM, Basford MA, Roden DM, Denny JC (2011) Heart Rhythm 8(2): 271-7
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  240. Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science. Denny JC, Ritchie MD, Crawford DC, Schildcrout JS, Ramirez AH, Pulley JM, Basford MA, Masys DR, Haines JL, Roden DM (2010) Circulation 122(20): 2016-21
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  241. Generating Clinical Notes for Electronic Health Record Systems. Rosenbloom ST, Stead WW, Denny JC, Giuse D, Lorenzi NM, Brown SH, Johnson KB (2010) Appl Clin Inform 1(3): 232-243
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  242. Integrating existing natural language processing tools for medication extraction from discharge summaries. Doan S, Bastarache L, Klimkowski S, Denny JC, Xu H (2010) J Am Med Inform Assoc 17(5): 528-31
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  243. Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records. Dumitrescu L, Ritchie MD, Brown-Gentry K, Pulley JM, Basford M, Denny JC, Oksenberg JR, Roden DM, Haines JL, Crawford DC (2010) Genet Med 12(10): 648-50
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  244. An analytical approach to characterize morbidity profile dissimilarity between distinct cohorts using electronic medical records. Schildcrout JS, Basford MA, Pulley JM, Masys DR, Roden DM, Wang D, Chute CG, Kullo IJ, Carrell D, Peissig P, Kho A, Denny JC (2010) J Biomed Inform 43(6): 914-23
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  245. Extracting timing and status descriptors for colonoscopy testing from electronic medical records. Denny JC, Peterson JF, Choma NN, Xu H, Miller RA, Bastarache L, Peterson NB (2010) J Am Med Inform Assoc 17(4): 383-8
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  246. The disclosure of diagnosis codes can breach research participants' privacy. Loukides G, Denny JC, Malin B (2010) J Am Med Inform Assoc 17(3): 322-7
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  247. Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record. Ritchie MD, Denny JC, Crawford DC, Ramirez AH, Weiner JB, Pulley JM, Basford MA, Brown-Gentry K, Balser JR, Masys DR, Haines JL, Roden DM (2010) Am J Hum Genet 86(4): 560-72
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  248. Development of inpatient risk stratification models of acute kidney injury for use in electronic health records. Matheny ME, Miller RA, Ikizler TA, Waitman LR, Denny JC, Schildcrout JS, Dittus RS, Peterson JF (2010) Med Decis Making 30(6): 639-50
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  249. Development of a natural language processing system to identify timing and status of colonoscopy testing in electronic medical records. Denny JC, Peterson JF, Choma NN, Xu H, Miller RA, Bastarache L, Peterson NB (2009) AMIA Annu Symp Proc : 141
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  250. PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations. Denny JC, Ritchie MD, Basford MA, Pulley JM, Bastarache L, Brown-Gentry K, Wang D, Masys DR, Roden DM, Crawford DC (2010) Bioinformatics 26(9): 1205-10
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  251. MedEx: a medication information extraction system for clinical narratives. Xu H, Stenner SP, Doan S, Johnson KB, Waitman LR, Denny JC (2010) J Am Med Inform Assoc 17(1): 19-24
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  252. Evaluation of a method to identify and categorize section headers in clinical documents. Denny JC, Spickard A, Johnson KB, Peterson NB, Peterson JF, Miller RA (2009) J Am Med Inform Assoc 16(6): 806-15
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  253. Tracking medical students' clinical experiences using natural language processing. Denny JC, Bastarache L, Sastre EA, Spickard A (2009) J Biomed Inform 42(5): 781-9
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  254. Development and evaluation of a clinical note section header terminology. Denny JC, Miller RA, Johnson KB, Spickard A (2008) AMIA Annu Symp Proc : 156-60
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  255. Automated capture and assessment of medical student clinical experience. Denny JC, Spickard A (2008) AMIA Annu Symp Proc : 926
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  256. Identifying QT prolongation from ECG impressions using a general-purpose Natural Language Processor. Denny JC, Miller RA, Waitman LR, Arrieta MA, Peterson JF (2009) Int J Med Inform : S34-42
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  257. Analysis of a computerized sign-out tool: identification of unanticipated uses and contradictory content. Campion TR, Denny JC, Weinberg ST, Lorenzi NM, Waitman LR (2007) AMIA Annu Symp Proc : 99-104
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  258. Automatic capture of student notes to augment mentor feedback and student performance on patient write-ups. Spickard A, Gigante J, Stein G, Denny JC (2008) J Gen Intern Med 23(7): 979-84
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  259. Increased hospital mortality in patients with bedside hippus. Denny JC, Arndt FV, Dupont WD, Neilson EG (2008) Am J Med 121(3): 239-45
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  260. Identifying QT prolongation from ECG impressions using natural language processing and negation detection. Denny JC, Peterson JF (2007) Stud Health Technol Inform 129(Pt 2): 1283-8
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  261. Analysis of medical student content searches that resulted in unidentified UMLS concepts. Rosenbaum BP, Denny JC, Spickard A (2006) AMIA Annu Symp Proc : 1079
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  262. Can users estimate their usage of a web-based application? Validating a self-report usage questionnaire. Wehbe FH, Denny JC, Spickard A (2005) AMIA Annu Symp Proc : 1151
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