David Vigerust
Last active: 12/2/2016


My interests focus around areas of healthcare, PGx, and diagnositics.  I am trained in immunology and infectious disease.

My other interests include infectious disease, oncology, innate immunity, traumatic brain injury, neuro-oncology (meningioma and glioma), neuroinflammation, neurodegeneration (ALS, Multiple Sclerosis, Muscular Distrophy and Spinal Muscular Atrophy) and polymicrobial approaches to improved biofuels.


The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. High-risk periodontal pathogens contribute to the pathogenesis of atherosclerosis. Bale BF, Doneen AL, Vigerust DJ (2017) Postgrad Med J 93(1098): 215-220
    › Primary publication · 27899684 (PubMed) · PMC5520251 (PubMed Central)
  2. Role of Haptoglobin in Health and Disease: A Focus on Diabetes. MacKellar M, Vigerust DJ (2016) Clin Diabetes 34(3): 148-57
    › Primary publication · 27621532 (PubMed) · PMC5019011 (PubMed Central)
  3. Hp: an inflammatory indicator in cardiovascular disease. Graves KL, Vigerust DJ (2016) Future Cardiol 12(4): 471-81
    › Primary publication · 27203711 (PubMed)
  4. Stable Expression and Characterization of an Optimized Mannose Receptor. Vigerust DJ, Vick S, Shepherd VL (2015) J Clin Cell Immunol 6(3)
    › Primary publication · 26581716 (PubMed) · PMC4645283 (PubMed Central)
  5. Interaction of members of the heat shock protein-70 family with the macrophage mannose receptor. Yang S, Vigerust DJ, Shepherd VL (2013) J Leukoc Biol 93(4): 529-36
    › Primary publication · 23345393 (PubMed) · PMC3597836 (PubMed Central)
  6. Characterization of functional mannose receptor in a continuous hybridoma cell line. Vigerust DJ, Vick S, Shepherd VL (2012) BMC Immunol : 51
    › Primary publication · 22967244 (PubMed) · PMC3495026 (PubMed Central)
  7. First complete and productive cell culture model for members of the genus Iridovirus. D'Costa SM, Vigerust DJ, Perales-Hull MR, Lodhi SA, Viravathana P, Bilimoria SL (2012) Arch Virol 157(11): 2171-8
    › Primary publication · 22828780 (PubMed)
  8. Mitogen-activated protein kinases and NFkappaB are involved in SP-A-enhanced responses of macrophages to mycobacteria. Lopez JP, Vigerust DJ, Shepherd VL (2009) Respir Res : 60
    › Primary publication · 19566962 (PubMed) · PMC2717924 (PubMed Central)
  9. Chloroquine is effective against influenza A virus in vitro but not in vivo. Vigerust DJ, McCullers JA (2007) Influenza Other Respir Viruses 1(5-6): 189-92
    › Primary publication · 19453426 (PubMed) · PMC4941887 (PubMed Central)
  10. N-linked glycosylation attenuates H3N2 influenza viruses. Vigerust DJ, Ulett KB, Boyd KL, Madsen J, Hawgood S, McCullers JA (2007) J Virol 81(16): 8593-600
    › Primary publication · 17553891 (PubMed) · PMC1951338 (PubMed Central)
  11. Virus glycosylation: role in virulence and immune interactions. Vigerust DJ, Shepherd VL (2007) Trends Microbiol 15(5): 211-8
    › Primary publication · 17398101 (PubMed)
  12. HIV-1 Nef mediates post-translational down-regulation and redistribution of the mannose receptor. Vigerust DJ, Egan BS, Shepherd VL (2005) J Leukoc Biol 77(4): 522-34
    › Primary publication · 15637102 (PubMed)
  13. Perpetuation of inflammation associated with experimental arthritis: the role of macrophage activation by neutrophilic myeloperoxidase. Gelderman MP, Stuart R, Vigerust D, Fuhrmann S, Lefkowitz DL, Allen RC, Lefkowitz SS, Graham S (1998) Mediators Inflamm 7(6): 381-9
    › Primary publication · 9927230 (PubMed) · PMC1781873 (PubMed Central)