Karoly Mirnics
Last active: 2/12/2015

Profile

The primary interest of the laboratory is centered around the transcriptome analysis of schizophrenia in the prefrontal cortex and superior temporal gyrus, as well as on the effect of antipsychotic medications. These studies will also address gender differences in schizophrenia at the molecular level. Furthermore, we will try to better understand the molecular phenotype of layer 3 cortical cells in the prefrontal cortex and analyze the molecular changes that occur in layer 3 cells in subjects with schizophrenia. In addition, we are interested in 1) Environmental influences on neuronal gene expression, 2) Neuroprotection by physical activity and 3) Gene expression patterns across human brain disorders.

Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Inhibition of parvalbumin-expressing interneurons results in complex behavioral changes. Brown JA, Ramikie TS, Schmidt MJ, Báldi R, Garbett K, Everheart MG, Warren LE, Gellért L, Horváth S, Patel S, Mirnics K (2015) Mol Psychiatry 20(12): 1499-507
    › Primary publication · 25623945 (PubMed) · PMC4516717 (PubMed Central)
  2. Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia. Brown JA, Sherrod SD, Goodwin CR, Brewer B, Yang L, Garbett KA, Li D, McLean JA, Wikswo JP, Mirnics K (2014) J Neuroinflammation : 183
    › Primary publication · 25374324 (PubMed) · PMC4233071 (PubMed Central)
  3. Coordinated messenger RNA/microRNA changes in fibroblasts of patients with major depression. Garbett KA, Vereczkei A, Kálmán S, Brown JA, Taylor WD, Faludi G, Korade Ž, Shelton RC, Mirnics K (2015) Biol Psychiatry 77(3): 256-265
    › Primary publication · 25016317 (PubMed) · PMC4254393 (PubMed Central)
  4. Clues from the cloud. Horváth S, Mirnics K (2014) Am J Psychiatry 171(7): 705-8
    › Primary publication · 24980163 (PubMed)
  5. Neurodevelopment, GABA system dysfunction, and schizophrenia. Schmidt MJ, Mirnics K (2015) Neuropsychopharmacology 40(1): 190-206
    › Primary publication · 24759129 (PubMed) · PMC4262918 (PubMed Central)
  6. Hippocampal immunostaining of CCK-GAD1 transgenic mice. Schmidt MJ, Horvath S, Ebert P, Norris JL, Seeley EH, Brown J, Gellert L, Everheart M, Garbett KA, Grice TW, Caprioli RM, Mirnics K (2014) Mol Psychiatry 19(5): 529
    › Primary publication · 24755516 (PubMed)
  7. Schizophrenia as a disorder of molecular pathways. Horváth S, Mirnics K (2015) Biol Psychiatry 77(1): 22-8
    › Primary publication · 24507510 (PubMed) · PMC4092052 (PubMed Central)
  8. Programmed to be human? Korade Z, Mirnics K (2014) Neuron 81(2): 224-6
    › Primary publication · 24462090 (PubMed) · PMC3950304 (PubMed Central)
  9. Modulation of behavioral networks by selective interneuronal inactivation. Schmidt MJ, Horvath S, Ebert P, Norris JL, Seeley EH, Brown J, Gellert L, Everheart M, Garbett KA, Grice TW, Caprioli RM, Mirnics K (2014) Mol Psychiatry 19(5): 580-7
    › Primary publication · 24322205 (PubMed) · PMC4179403 (PubMed Central)
  10. Metabolic stress-induced microRNA and mRNA expression profiles of human fibroblasts. Kálmán S, Garbett KA, Vereczkei A, Shelton RC, Korade Z, Mirnics K (2014) Exp Cell Res 320(2): 343-53
    › Primary publication · 24246224 (PubMed) · PMC3902643 (PubMed Central)
  11. The role of cannabinoid 1 receptor expressing interneurons in behavior. Brown JA, Horváth S, Garbett KA, Schmidt MJ, Everheart M, Gellért L, Ebert P, Mirnics K (2014) Neurobiol Dis : 210-21
    › Primary publication · 24239560 (PubMed) · PMC3946968 (PubMed Central)
  12. Lost their ways? Brown JA, Mirnics K (2013) Biol Psychiatry 74(6): 398-9
    › Primary publication · 23968986 (PubMed)
  13. The genome in three dimensions: a new frontier in human brain research. Mitchell AC, Bharadwaj R, Whittle C, Krueger W, Mirnics K, Hurd Y, Rasmussen T, Akbarian S (2014) Biol Psychiatry 75(12): 961-9
    › Primary publication · 23958183 (PubMed) · PMC3925763 (PubMed Central)
  14. Antioxidant supplementation ameliorates molecular deficits in Smith-Lemli-Opitz syndrome. Korade Z, Xu L, Harrison FE, Ahsen R, Hart SE, Folkes OM, Mirnics K, Porter NA (2014) Biol Psychiatry 75(3): 215-22
    › Primary publication · 23896203 (PubMed) · PMC3874268 (PubMed Central)
  15. Immune system disturbances in schizophrenia. Horváth S, Mirnics K (2014) Biol Psychiatry 75(4): 316-23
    › Primary publication · 23890736 (PubMed) · PMC3841236 (PubMed Central)
  16. Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia. Bharadwaj R, Jiang Y, Mao W, Jakovcevski M, Dincer A, Krueger W, Garbett K, Whittle C, Tushir JS, Liu J, Sequeira A, Vawter MP, Gardner PD, Casaccia P, Rasmussen T, Bunney WE, Mirnics K, Futai K, Akbarian S (2013) J Neurosci 33(29): 11839-51
    › Primary publication · 23864674 (PubMed) · PMC3713726 (PubMed Central)
  17. Genes for endosomal NHE6 and NHE9 are misregulated in autism brains. Schwede M, Garbett K, Mirnics K, Geschwind DH, Morrow EM (2014) Mol Psychiatry 19(3): 277-9
    › Primary publication · 23508127 (PubMed) · PMC3932404 (PubMed Central)
  18. Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells. Xu L, Korade Z, Rosado DA, Mirnics K, Porter NA (2013) J Lipid Res 54(4): 1135-43
    › Primary publication · 23381570 (PubMed) · PMC3605989 (PubMed Central)
  19. Physical activity is linked to ceruloplasmin in the striatum of intact but not MPTP-treated primates. Leak RK, Garbett KA, Dettmer AM, Zhang Z, Mirnics K, Cameron JL (2012) Cell Tissue Res 350(3): 401-7
    › Primary publication · 22940761 (PubMed) · PMC3779886 (PubMed Central)
  20. Effects of maternal immune activation on gene expression patterns in the fetal brain. Garbett KA, Hsiao EY, Kálmán S, Patterson PH, Mirnics K (2012) Transl Psychiatry : e98
    › Primary publication · 22832908 (PubMed) · PMC3337077 (PubMed Central)
  21. Immune system gene dysregulation in autism and schizophrenia. Michel M, Schmidt MJ, Mirnics K (2012) Dev Neurobiol 72(10): 1277-87
    › Primary publication · 22753382 (PubMed) · PMC3435446 (PubMed Central)
  22. A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2. Zhang X, Garbett K, Veeraraghavalu K, Wilburn B, Gilmore R, Mirnics K, Sisodia SS (2012) J Neurosci 32(25): 8633-48
    › Primary publication · 22723704 (PubMed) · PMC3467018 (PubMed Central)
  23. Lipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndrome. Korade Z, Xu L, Mirnics K, Porter NA (2013) J Inherit Metab Dis 36(1): 113-22
    › Primary publication · 22718275 (PubMed) · PMC3674764 (PubMed Central)
  24. Modeling interneuron dysfunction in schizophrenia. Schmidt MJ, Mirnics K (2012) Dev Neurosci 34(2-3): 152-8
    › Primary publication · 22571893 (PubMed)
  25. Gene transcripts associated with BMI in the motor cortex and caudate nucleus of calorie restricted rhesus monkeys. Mitchell AC, Leak RK, Zigmond MJ, Cameron JL, Mirnics K (2012) Genomics 99(3): 144-51
    › Primary publication · 22227022 (PubMed) · PMC3292695 (PubMed Central)
  26. Genetic predisposition to schizophrenia: what did we learn and what does the future hold? Vereczkei A, Mirnics K (2011) Neuropsychopharmacol Hung 13(4): 205-10
    › Primary publication · 22184188 (PubMed)
  27. DHCEO accumulation is a critical mediator of pathophysiology in a Smith-Lemli-Opitz syndrome model. Xu L, Mirnics K, Bowman AB, Liu W, Da J, Porter NA, Korade Z (2012) Neurobiol Dis 45(3): 923-9
    › Primary publication · 22182693 (PubMed) · PMC3674775 (PubMed Central)
  28. Physical activity-associated gene expression signature in nonhuman primate motor cortex. Mitchell AC, Leak RK, Garbett K, Zigmond MJ, Cameron JL, Mirnics K (2012) Obesity (Silver Spring) 20(3): 692-8
    › Primary publication · 22016091 (PubMed) · PMC3872776 (PubMed Central)
  29. Wnt signaling as a potential therapeutic target for frontotemporal dementia. Korade Z, Mirnics K (2011) Neuron 71(6): 955-7
    › Primary publication · 21943593 (PubMed) · PMC3183459 (PubMed Central)
  30. Expressing the mind. Mirnics K, Blakemore JG (2012) Neurobiol Dis 45(1): 1-2
    › Primary publication · 21930209 (PubMed)
  31. Gene expression profiling of the brain: pondering facts and fiction. Mitchell AC, Mirnics K (2012) Neurobiol Dis 45(1): 3-7
    › Primary publication · 21689753 (PubMed) · PMC3210391 (PubMed Central)
  32. Gene expression: The autism disconnect. Korade Z, Mirnics K (2011) Nature 474(7351): 294-5
    › Primary publication · 21677744 (PubMed)
  33. Synaptic changes in the brain of subjects with schizophrenia. Faludi G, Mirnics K (2011) Int J Dev Neurosci 29(3): 305-9
    › Primary publication · 21382468 (PubMed) · PMC3074034 (PubMed Central)
  34. Schizophrenia. Special issue introduction. Mirnics K (2011) Int J Dev Neurosci 29(3): 189-91
    › Primary publication · 21333728 (PubMed)
  35. Molecular correlates of spontaneous activity in non-human primates. Mitchell AC, Aldridge G, Kohler S, Stanton G, Sullivan E, Garbett K, Faludi G, Mirnics K, Cameron JL, Greenough W (2010) J Neural Transm (Vienna) 117(12): 1353-8
    › Primary publication · 20838826 (PubMed) · PMC3649869 (PubMed Central)
  36. Analyzing schizophrenia by DNA microarrays. Horváth S, Janka Z, Mirnics K (2011) Biol Psychiatry 69(2): 157-62
    › Primary publication · 20801428 (PubMed) · PMC2994975 (PubMed Central)
  37. Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression. Shelton RC, Claiborne J, Sidoryk-Wegrzynowicz M, Reddy R, Aschner M, Lewis DA, Mirnics K (2011) Mol Psychiatry 16(7): 751-62
    › Primary publication · 20479761 (PubMed) · PMC2928407 (PubMed Central)
  38. Novel animal models for studying complex brain disorders: BAC-driven miRNA-mediated in vivo silencing of gene expression. Garbett KA, Horváth S, Ebert PJ, Schmidt MJ, Lwin K, Mitchell A, Levitt P, Mirnics K (2010) Mol Psychiatry 15(10): 987-95
    › Primary publication · 20125089 (PubMed) · PMC3011211 (PubMed Central)
  39. Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency. Zigmond MJ, Cameron JL, Leak RK, Mirnics K, Russell VA, Smeyne RJ, Smith AD (2009) Parkinsonism Relat Disord : S42-5
    › Primary publication · 20083005 (PubMed)
  40. Infragranular gene expression disturbances in the prefrontal cortex in schizophrenia: signature of altered neural development? Arion D, Horváth S, Lewis DA, Mirnics K (2010) Neurobiol Dis 37(3): 738-46
    › Primary publication · 20034564 (PubMed) · PMC2823856 (PubMed Central)
  41. The organization of the transcriptional network in specific neuronal classes. Winden KD, Oldham MC, Mirnics K, Ebert PJ, Swan CH, Levitt P, Rubenstein JL, Horvath S, Geschwind DH (2009) Mol Syst Biol : 291
    › Primary publication · 19638972 (PubMed) · PMC2724976 (PubMed Central)
  42. Breaking the gene barrier in schizophrenia. Horváth S, Mirnics K (2009) Nat Med 15(5): 488-90
    › Primary publication · 19424205 (PubMed) · PMC4123735 (PubMed Central)
  43. What is in the brain soup? Mirnics K (2008) Nat Neurosci 11(11): 1237-8
    › Primary publication · 18956006 (PubMed)
  44. Molecular consequences of altered neuronal cholesterol biosynthesis. Korade Z, Kenworthy AK, Mirnics K (2009) J Neurosci Res 87(4): 866-75
    › Primary publication · 18951487 (PubMed) · PMC4360921 (PubMed Central)
  45. Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice. Mirnics K, Norstrom EM, Garbett K, Choi SH, Zhang X, Ebert P, Sisodia SS (2008) Mol Neurodegener : 14
    › Primary publication · 18834536 (PubMed) · PMC2569036 (PubMed Central)
  46. Transcriptome alterations in the prefrontal cortex of subjects with schizophrenia who committed suicide. Garbett K, Gal-Chis R, Gaszner G, Lewis DA, Mirnics K (2008) Neuropsychopharmacol Hung 10(1): 9-14
    › Primary publication · 18771015 (PubMed)
  47. NRIF is a regulator of neuronal cholesterol biosynthesis genes. Korade Z, Kenchappa RS, Mirnics K, Carter BD (2009) J Mol Neurosci 38(2): 152-8
    › Primary publication · 18677445 (PubMed) · PMC3118441 (PubMed Central)
  48. Immune transcriptome alterations in the temporal cortex of subjects with autism. Garbett K, Ebert PJ, Mitchell A, Lintas C, Manzi B, Mirnics K, Persico AM (2008) Neurobiol Dis 30(3): 303-11
    › Primary publication · 18378158 (PubMed) · PMC2693090 (PubMed Central)
  49. It is time to take a stand for medical research and against terrorism targeting medical scientists. Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA, Cook EH, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R (2008) Biol Psychiatry 63(8): 725-7
    › Primary publication · 18371494 (PubMed)
  50. Involvement of the PRKCB1 gene in autistic disorder: significant genetic association and reduced neocortical gene expression. Lintas C, Sacco R, Garbett K, Mirnics K, Militerni R, Bravaccio C, Curatolo P, Manzi B, Schneider C, Melmed R, Elia M, Pascucci T, Puglisi-Allegra S, Reichelt KL, Persico AM (2009) Mol Psychiatry 14(7): 705-18
    › Primary publication · 18317465 (PubMed)
  51. Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia. Hashimoto T, Bazmi HH, Mirnics K, Wu Q, Sampson AR, Lewis DA (2008) Am J Psychiatry 165(4): 479-89
    › Primary publication · 18281411 (PubMed) · PMC2894608 (PubMed Central)
  52. Maternal immune activation alters fetal brain development through interleukin-6. Smith SE, Li J, Garbett K, Mirnics K, Patterson PH (2007) J Neurosci 27(40): 10695-702
    › Primary publication · 17913903 (PubMed) · PMC2387067 (PubMed Central)
  53. Activation of the ciliary neurotrophic factor (CNTF) signalling pathway in cortical neurons of multiple sclerosis patients. Dutta R, McDonough J, Chang A, Swamy L, Siu A, Kidd GJ, Rudick R, Mirnics K, Trapp BD (2007) Brain 130(Pt 10): 2566-76
    › Primary publication · 17898009 (PubMed)
  54. Disruption of cerebral cortex MET signaling in autism spectrum disorder. Campbell DB, D'Oronzio R, Garbett K, Ebert PJ, Mirnics K, Levitt P, Persico AM (2007) Ann Neurol 62(3): 243-50
    › Primary publication · 17696172 (PubMed)
  55. Regulator of G Signaling 16 is a marker for the distinct endoplasmic reticulum stress state associated with aggregated mutant alpha1-antitrypsin Z in the classical form of alpha1-antitrypsin deficiency. Hidvegi T, Mirnics K, Hale P, Ewing M, Beckett C, Perlmutter DH (2007) J Biol Chem 282(38): 27769-80
    › Primary publication · 17635928 (PubMed)
  56. Molecular evidence for increased expression of genes related to immune and chaperone function in the prefrontal cortex in schizophrenia. Arion D, Unger T, Lewis DA, Levitt P, Mirnics K (2007) Biol Psychiatry 62(7): 711-21
    › Primary publication · 17568569 (PubMed) · PMC2080683 (PubMed Central)
  57. Linkage disequilibrium patterns and functional analysis of RGS4 polymorphisms in relation to schizophrenia. Chowdari KV, Bamne M, Wood J, Talkowski ME, Mirnics K, Levitt P, Lewis DA, Nimgaonkar VL (2008) Schizophr Bull 34(1): 118-26
    › Primary publication · 17515439 (PubMed) · PMC2632380 (PubMed Central)
  58. Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia. Hashimoto T, Arion D, Unger T, Maldonado-Avilés JG, Morris HM, Volk DW, Mirnics K, Lewis DA (2008) Mol Psychiatry 13(2): 147-61
    › Primary publication · 17471287 (PubMed) · PMC2882638 (PubMed Central)
  59. Molecular markers distinguishing supragranular and infragranular layers in the human prefrontal cortex. Arion D, Unger T, Lewis DA, Mirnics K (2007) Eur J Neurosci 25(6): 1843-54
    › Primary publication · 17432970 (PubMed)
  60. Amygdala gene expression correlates of social behavior in monkeys experiencing maternal separation. Sabatini MJ, Ebert P, Lewis DA, Levitt P, Cameron JL, Mirnics K (2007) J Neurosci 27(12): 3295-304
    › Primary publication · 17376990 (PubMed)
  61. Transcriptome alterations in schizophrenia: disturbing the functional architecture of the dorsolateral prefrontal cortex. Lewis DA, Mirnics K (2006) Prog Brain Res : 141-52
    › Primary publication · 17027695 (PubMed)
  62. Functional genomic methodologies. Ginsberg SD, Mirnics K (2006) Prog Brain Res : 15-40
    › Primary publication · 17027690 (PubMed)
  63. Making the case for a candidate vulnerability gene in schizophrenia: Convergent evidence for regulator of G-protein signaling 4 (RGS4). Levitt P, Ebert P, Mirnics K, Nimgaonkar VL, Lewis DA (2006) Biol Psychiatry 60(6): 534-7
    › Primary publication · 16860780 (PubMed)
  64. DNA pooling: a comprehensive, multi-stage association analysis of ACSL6 and SIRT5 polymorphisms in schizophrenia. Chowdari KV, Northup A, Pless L, Wood J, Joo YH, Mirnics K, Lewis DA, Levitt PR, Bacanu SA, Nimgaonkar VL (2007) Genes Brain Behav 6(3): 229-39
    › Primary publication · 16827919 (PubMed)
  65. Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood. Glorioso C, Sabatini M, Unger T, Hashimoto T, Monteggia LM, Lewis DA, Mirnics K (2006) Mol Psychiatry 11(7): 633-48
    › Primary publication · 16702976 (PubMed)
  66. Synaptic plasticity in the adult spinal dorsal horn: the appearance of new functional connections following peripheral nerve regeneration. Koerber HR, Mirnics K, Lawson JJ (2006) Exp Neurol 200(2): 468-79
    › Primary publication · 16696973 (PubMed)
  67. Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples. Talkowski ME, Seltman H, Bassett AS, Brzustowicz LM, Chen X, Chowdari KV, Collier DA, Cordeiro Q, Corvin AP, Deshpande SN, Egan MF, Gill M, Kendler KS, Kirov G, Heston LL, Levitt P, Lewis DA, Li T, Mirnics K, Morris DW, Norton N, O'Donovan MC, Owen MJ, Richard C, Semwal P, Sobell JL, St Clair D, Straub RE, Thelma BK, Vallada H, Weinberger DR, Williams NM, Wood J, Zhang F, Devlin B, Nimgaonkar VL (2006) Biol Psychiatry 60(2): 152-62
    › Primary publication · 16631129 (PubMed) · PMC3133764 (PubMed Central)
  68. Critical appraisal of DNA microarrays in psychiatric genomics. Mirnics K, Levitt P, Lewis DA (2006) Biol Psychiatry 60(2): 163-76
    › Primary publication · 16616896 (PubMed)
  69. Correlation of transcriptome profile with electrical activity in temporal lobe epilepsy. Arion D, Sabatini M, Unger T, Pastor J, Alonso-Nanclares L, Ballesteros-Yáñez I, García Sola R, Muñoz A, Mirnics K, DeFelipe J (2006) Neurobiol Dis 22(2): 374-87
    › Primary publication · 16480884 (PubMed)
  70. Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients. Dutta R, McDonough J, Yin X, Peterson J, Chang A, Torres T, Gudz T, Macklin WB, Lewis DA, Fox RJ, Rudick R, Mirnics K, Trapp BD (2006) Ann Neurol 59(3): 478-89
    › Primary publication · 16392116 (PubMed)
  71. Transcriptome differences between the frontal cortex and hippocampus of wild-type and humanized presenilin-1 transgenic mice. Unger T, Korade Z, Lazarov O, Terrano D, Schor NF, Sisodia SS, Mirnics K (2005) Am J Geriatr Psychiatry 13(12): 1041-51
    › Primary publication · 16319296 (PubMed)
  72. True and false discovery in DNA microarray experiments: transcriptome changes in the hippocampus of presenilin 1 mutant mice. Unger T, Korade Z, Lazarov O, Terrano D, Sisodia SS, Mirnics K (2005) Methods 37(3): 261-73
    › Primary publication · 16308155 (PubMed)
  73. DNA self-polymers as microarray probes improve assay sensitivity. Hollingshead D, Korade Z, Lewis DA, Levitt P, Mirnics K (2006) J Neurosci Methods 151(2): 216-23
    › Primary publication · 16165216 (PubMed)
  74. P75 neurotrophin receptor regulates expression of neural cell adhesion molecule 1. Mirnics ZK, Yan C, Portugal C, Kim TW, Saragovi HU, Sisodia SS, Mirnics K, Schor NF (2005) Neurobiol Dis 20(3): 969-85
    › Primary publication · 16006137 (PubMed)
  75. Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Lazarov O, Robinson J, Tang YP, Hairston IS, Korade-Mirnics Z, Lee VM, Hersh LB, Sapolsky RM, Mirnics K, Sisodia SS (2005) Cell 120(5): 701-13
    › Primary publication · 15766532 (PubMed)
  76. Platform influence on DNA microarray data in postmortem brain research. Hollingshead D, Lewis DA, Mirnics K (2005) Neurobiol Dis 18(3): 649-55
    › Primary publication · 15755690 (PubMed)
  77. Altered expression of 14-3-3 genes in the prefrontal cortex of subjects with schizophrenia. Middleton FA, Peng L, Lewis DA, Levitt P, Mirnics K (2005) Neuropsychopharmacology 30(5): 974-83
    › Primary publication · 15726117 (PubMed)
  78. Presenilin-1-dependent transcriptome changes. Mirnics K, Korade Z, Arion D, Lazarov O, Unger T, Macioce M, Sabatini M, Terrano D, Douglass KC, Schor NF, Sisodia SS (2005) J Neurosci 25(6): 1571-8
    › Primary publication · 15703411 (PubMed)
  79. Heat shock protein 12A shows reduced expression in the prefrontal cortex of subjects with schizophrenia. Pongrac JL, Middleton FA, Peng L, Lewis DA, Levitt P, Mirnics K (2004) Biol Psychiatry 56(12): 943-50
    › Primary publication · 15601604 (PubMed)
  80. DNA microarray analysis of postmortem brain tissue. Mirnics K, Levitt P, Lewis DA (2004) Int Rev Neurobiol : 153-81
    › Primary publication · 15474590 (PubMed)
  81. Progress in the use of microarray technology to study the neurobiology of disease. Mirnics K, Pevsner J (2004) Nat Neurosci 7(5): 434-9
    › Primary publication · 15114354 (PubMed)
  82. Microarray analysis of Lyn-deficient B cells reveals germinal center-associated nuclear protein and other genes associated with the lymphoid germinal center. Mirnics ZK, Caudell E, Gao Y, Kuwahara K, Sakaguchi N, Kurosaki T, Burnside J, Mirnics K, Corey SJ (2004) J Immunol 172(7): 4133-41
    › Primary publication · 15034025 (PubMed)
  83. DNA microarray profiling of developing PS1-deficient mouse brain reveals complex and coregulated expression changes. Mirnics ZK, Mirnics K, Terrano D, Lewis DA, Sisodia SS, Schor NF (2003) Mol Psychiatry 8(10): 863-78
    › Primary publication · 14515137 (PubMed)
  84. Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia. Hashimoto T, Volk DW, Eggan SM, Mirnics K, Pierri JN, Sun Z, Sampson AR, Lewis DA (2003) J Neurosci 23(15): 6315-26
    › Primary publication · 12867516 (PubMed)
  85. Delineating novel signature patterns of altered gene expression in schizophrenia using gene microarrays. Mirnics K, Middleton FA, Lewis DA, Levitt P (2001) ScientificWorldJournal : 114-6
    › Primary publication · 12805694 (PubMed) · PMC6084111 (PubMed Central)
  86. Gene expression profiling with DNA microarrays: advancing our understanding of psychiatric disorders. Pongrac J, Middleton FA, Lewis DA, Levitt P, Mirnics K (2002) Neurochem Res 27(10): 1049-63
    › Primary publication · 12462404 (PubMed)
  87. Association and linkage analyses of RGS4 polymorphisms in schizophrenia. Chowdari KV, Mirnics K, Semwal P, Wood J, Lawrence E, Bhatia T, Deshpande SN, B K T, Ferrell RE, Middleton FA, Devlin B, Levitt P, Lewis DA, Nimgaonkar VL (2002) Hum Mol Genet 11(12): 1373-80
    › Primary publication · 12023979 (PubMed)
  88. Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia. Middleton FA, Mirnics K, Pierri JN, Lewis DA, Levitt P (2002) J Neurosci 22(7): 2718-29
    › Primary publication · 11923437 (PubMed)
  89. The human genome: gene expression profiling and schizophrenia. Mirnics K, Middleton FA, Lewis DA, Levitt P (2001) Am J Psychiatry 158(9): 1384
    › Primary publication · 11532720 (PubMed)
  90. Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse. Mirnics K, Middleton FA, Lewis DA, Levitt P (2001) Trends Neurosci 24(8): 479-86
    › Primary publication · 11476888 (PubMed)
  91. Genes and subtypes of schizophrenia. Mirnics K, Lewis DA (2001) Trends Mol Med 7(7): 281-3
    › Primary publication · 11425621 (PubMed)
  92. Microarrays in brain research: the good, the bad and the ugly. Mirnics K (2001) Nat Rev Neurosci 2(6): 444-7
    › Primary publication · 11389480 (PubMed)
  93. Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia. Mirnics K, Middleton FA, Stanwood GD, Lewis DA, Levitt P (2001) Mol Psychiatry 6(3): 293-301
    › Primary publication · 11326297 (PubMed)
  94. Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Mirnics K, Middleton FA, Marquez A, Lewis DA, Levitt P (2000) Neuron 28(1): 53-67
    › Primary publication · 11086983 (PubMed)
  95. Ultrastructural analysis of ectopic synaptic boutons arising from peripherally regenerated primary afferent fibers. Koerber HR, Mirnics K, Kavookjian AM, Light AR (1999) J Neurophysiol 81(4): 1636-44
    › Primary publication · 10200200 (PubMed)
  96. Properties of individual embryonic primary afferents and their spinal projections in the rat. Mirnics K, Koerber HR (1997) J Neurophysiol 78(3): 1590-600
    › Primary publication · 9310445 (PubMed)
  97. Plasticity of dorsal horn cell receptive fields after peripheral nerve regeneration. Koerber HR, Mirnics K (1996) J Neurophysiol 75(6): 2255-67
    › Primary publication · 8793739 (PubMed)
  98. Morphology of functional long-ranging primary afferent projections in the cat spinal cord. Koerber HR, Mirnics K (1995) J Neurophysiol 74(6): 2336-48
    › Primary publication · 8747196 (PubMed)
  99. Central sprouting and functional plasticity of regenerated primary afferents. Koerber HR, Mirnics K, Brown PB, Mendell LM (1994) J Neurosci 14(6): 3655-71
    › Primary publication · 8207480 (PubMed)
  100. Properties of regenerated primary afferents and their functional connections. Koerber HR, Mirnics K, Mendell LM (1995) J Neurophysiol 73(2): 693-702
    › Primary publication · 7760128 (PubMed)
  101. Prenatal development of rat primary afferent fibers: II. Central projections. Mirnics K, Koerber HR (1995) J Comp Neurol 355(4): 601-14
    › Primary publication · 7636034 (PubMed)
  102. Prenatal development of rat primary afferent fibers: I. Peripheral projections. Mirnics K, Koerber HR (1995) J Comp Neurol 355(4): 589-600
    › Primary publication · 7636033 (PubMed)