Fang Yan
Last active: 4/11/2016


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The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. GG: An Updated Strategy to Use Microbial Products to Promote Health. Yan F, Polk DB (2012) Funct Food Rev 4(2): 77-84
    › Primary publication · 24795791 (PubMed) · PMC4006995 (PubMed Central)
  2. Activation of EGFR and ERBB2 by Helicobacter pylori results in survival of gastric epithelial cells with DNA damage. Chaturvedi R, Asim M, Piazuelo MB, Yan F, Barry DP, Sierra JC, Delgado AG, Hill S, Casero RA, Bravo LE, Dominguez RL, Correa P, Polk DB, Washington MK, Rose KL, Schey KL, Morgan DR, Peek RM, Wilson KT (2014) Gastroenterology 146(7): 1739-51.e14
    › Primary publication · 24530706 (PubMed) · PMC4035375 (PubMed Central)
  3. Activation of the epidermal growth factor receptor in macrophages regulates cytokine production and experimental colitis. Lu N, Wang L, Cao H, Liu L, Van Kaer L, Washington MK, Rosen MJ, Dubé PE, Wilson KT, Ren X, Hao X, Polk DB, Yan F (2014) J Immunol 192(3): 1013-23
    › Primary publication · 24391216 (PubMed) · PMC4006992 (PubMed Central)
  4. A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor. Yan F, Liu L, Dempsey PJ, Tsai YH, Raines EW, Wilson CL, Cao H, Cao Z, Liu L, Polk DB (2013) J Biol Chem 288(42): 30742-30751
    › Primary publication · 24043629 (PubMed) · PMC3798544 (PubMed Central)
  5. Induction of COX-2 expression by Helicobacter pylori is mediated by activation of epidermal growth factor receptor in gastric epithelial cells. Sierra JC, Hobbs S, Chaturvedi R, Yan F, Wilson KT, Peek RM, Polk DB (2013) Am J Physiol Gastrointest Liver Physiol 305(2): G196-203
    › Primary publication · 23681474 (PubMed) · PMC3725681 (PubMed Central)
  6. Berberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells. Wang L, Cao H, Lu N, Liu L, Wang B, Hu T, Israel DA, Peek RM, Polk DB, Yan F (2013) PLoS One 8(2): e56666
    › Primary publication · 23457600 (PubMed) · PMC3573001 (PubMed Central)
  7. Epidermal growth factor receptor inhibits colitis-associated cancer in mice. Dubé PE, Yan F, Punit S, Girish N, McElroy SJ, Washington MK, Polk DB (2012) J Clin Invest 122(8): 2780-92
    › Primary publication · 22772467 (PubMed) · PMC3408743 (PubMed Central)
  8. Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor. Wang L, Liu L, Shi Y, Cao H, Chaturvedi R, Calcutt MW, Hu T, Ren X, Wilson KT, Polk DB, Yan F (2012) PLoS One 7(5): e36418
    › Primary publication · 22574158 (PubMed) · PMC3344856 (PubMed Central)
  9. Characterization of a probiotic-derived soluble protein which reveals a mechanism of preventive and treatment effects of probiotics on intestinal inflammatory diseases. Yan F, Polk DB (2012) Gut Microbes 3(1): 25-8
    › Primary publication · 22356855 (PubMed) · PMC3337122 (PubMed Central)
  10. Berberine promotes recovery of colitis and inhibits inflammatory responses in colonic macrophages and epithelial cells in DSS-treated mice. Yan F, Wang L, Shi Y, Cao H, Liu L, Washington MK, Chaturvedi R, Israel DA, Cao H, Wang B, Peek RM, Wilson KT, Polk DB (2012) Am J Physiol Gastrointest Liver Physiol 302(5): G504-14
    › Primary publication · 22173918 (PubMed) · PMC3311435 (PubMed Central)
  11. ErbB2 and ErbB3 regulate recovery from dextran sulfate sodium-induced colitis by promoting mouse colon epithelial cell survival. Zhang Y, Dubé PE, Washington MK, Yan F, Polk DB (2012) Lab Invest 92(3): 437-50
    › Primary publication · 22157714 (PubMed) · PMC3289719 (PubMed Central)
  12. Probiotics and immune health. Yan F, Polk DB (2011) Curr Opin Gastroenterol 27(6): 496-501
    › Primary publication · 21897224 (PubMed) · PMC4006993 (PubMed Central)
  13. Spermine oxidase mediates the gastric cancer risk associated with Helicobacter pylori CagA. Chaturvedi R, Asim M, Romero-Gallo J, Barry DP, Hoge S, de Sablet T, Delgado AG, Wroblewski LE, Piazuelo MB, Yan F, Israel DA, Casero RA, Correa P, Gobert AP, Polk DB, Peek RM, Wilson KT (2011) Gastroenterology 141(5): 1696-708.e1-2
    › Primary publication · 21839041 (PubMed) · PMC3202654 (PubMed Central)
  14. Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism. Yan F, Cao H, Cover TL, Washington MK, Shi Y, Liu L, Chaturvedi R, Peek RM, Wilson KT, Polk DB (2011) J Clin Invest 121(6): 2242-53
    › Primary publication · 21606592 (PubMed) · PMC3104743 (PubMed Central)
  15. TNF transactivation of EGFR stimulates cytoprotective COX-2 expression in gastrointestinal epithelial cells. Hobbs SS, Goettel JA, Liang D, Yan F, Edelblum KL, Frey MR, Mullane MT, Polk DB (2011) Am J Physiol Gastrointest Liver Physiol 301(2): G220-9
    › Primary publication · 21566012 (PubMed) · PMC3154604 (PubMed Central)
  16. Functional analysis of the p40 and p75 proteins from Lactobacillus casei BL23. Bäuerl C, Pérez-Martínez G, Yan F, Polk DB, Monedero V (2010) J Mol Microbiol Biotechnol 19(4): 231-41
    › Primary publication · 21178363 (PubMed) · PMC3019367 (PubMed Central)
  17. Disruption of NF-kappaB signalling by ancient microbial molecules: novel therapies of the future? Yan F, Polk DB (2010) Gut 59(4): 421-6
    › Primary publication · 20332512 (PubMed) · PMC3036986 (PubMed Central)
  18. Probiotics: progress toward novel therapies for intestinal diseases. Yan F, Polk DB (2010) Curr Opin Gastroenterol 26(2): 95-101
    › Primary publication · 19952741 (PubMed) · PMC3036989 (PubMed Central)
  19. Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis. Yan F, Cao H, Chaturvedi R, Krishna U, Hobbs SS, Dempsey PJ, Peek RM, Cover TL, Washington MK, Wilson KT, Polk DB (2009) Gastroenterology 136(4): 1297-1307, e1-3
    › Primary publication · 19250983 (PubMed) · PMC2878739 (PubMed Central)
  20. Helicobacter pylori regulates cellular migration and apoptosis by activation of phosphatidylinositol 3-kinase signaling. Nagy TA, Frey MR, Yan F, Israel DA, Polk DB, Peek RM (2009) J Infect Dis 199(5): 641-51
    › Primary publication · 19199544 (PubMed) · PMC2830010 (PubMed Central)
  21. TNFR1 promotes tumor necrosis factor-mediated mouse colon epithelial cell survival through RAF activation of NF-kappaB. Edelblum KL, Goettel JA, Koyama T, McElroy SJ, Yan F, Polk DB (2008) J Biol Chem 283(43): 29485-94
    › Primary publication · 18713739 (PubMed) · PMC2570867 (PubMed Central)
  22. Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis. Yamaoka T, Yan F, Cao H, Hobbs SS, Dise RS, Tong W, Polk DB (2008) Proc Natl Acad Sci U S A 105(33): 11772-7
    › Primary publication · 18701712 (PubMed) · PMC2575333 (PubMed Central)
  23. Mechanisms of probiotic action: Implications for therapeutic applications in inflammatory bowel diseases. Vanderpool C, Yan F, Polk DB (2008) Inflamm Bowel Dis 14(11): 1585-96
    › Primary publication · 18623173 (PubMed)
  24. Tumor necrosis factor inhibits ligand-stimulated EGF receptor activation through a TNF receptor 1-dependent mechanism. McElroy SJ, Frey MR, Yan F, Edelblum KL, Goettel JA, John S, Polk DB (2008) Am J Physiol Gastrointest Liver Physiol 295(2): G285-93
    › Primary publication · 18467504 (PubMed) · PMC2519857 (PubMed Central)
  25. Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism. Seth A, Yan F, Polk DB, Rao RK (2008) Am J Physiol Gastrointest Liver Physiol 294(4): G1060-9
    › Primary publication · 18292183 (PubMed) · PMC2653458 (PubMed Central)
  26. Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Yan F, Cao H, Cover TL, Whitehead R, Washington MK, Polk DB (2007) Gastroenterology 132(2): 562-75
    › Primary publication · 17258729 (PubMed) · PMC3036990 (PubMed Central)
  27. Probiotics as functional food in the treatment of diarrhea. Yan F, Polk DB (2006) Curr Opin Clin Nutr Metab Care 9(6): 717-21
    › Primary publication · 17053425 (PubMed)
  28. Regulation of apoptosis during homeostasis and disease in the intestinal epithelium. Edelblum KL, Yan F, Yamaoka T, Polk DB (2006) Inflamm Bowel Dis 12(5): 413-24
    › Primary publication · 16670531 (PubMed)
  29. Commensal bacteria in the gut: learning who our friends are. Yan F, Polk DB (2004) Curr Opin Gastroenterol 20(6): 565-71
    › Primary publication · 15703684 (PubMed)
  30. Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation. Yan F, John SK, Wilson G, Jones DS, Washington MK, Polk DB (2004) J Clin Invest 114(9): 1272-80
    › Primary publication · 15520859 (PubMed) · PMC524224 (PubMed Central)
  31. Tumor necrosis factor regulates intestinal epithelial cell migration by receptor-dependent mechanisms. Corredor J, Yan F, Shen CC, Tong W, John SK, Wilson G, Whitehead R, Polk DB (2003) Am J Physiol Cell Physiol 284(4): C953-61
    › Primary publication · 12466150 (PubMed)
  32. Probiotic bacterium prevents cytokine-induced apoptosis in intestinal epithelial cells. Yan F, Polk DB (2002) J Biol Chem 277(52): 50959-65
    › Primary publication · 12393915 (PubMed) · PMC4006994 (PubMed Central)