John Wikswo
Faculty Member
Last active: 2/19/2015

Profile

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Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Biology coming full circle: joining the whole and the parts. Wikswo JP, Porter AP (2015) Exp Biol Med (Maywood) 240(1): 3-7
    › Primary publication · 25583953 (PubMed) · PMC4391629 (PubMed Central)
  2. Engineered three-dimensional microfluidic device for interrogating cell-cell interactions in the tumor microenvironment. Hockemeyer K, Janetopoulos C, Terekhov A, Hofmeister W, Vilgelm A, Costa L, Wikswo JP, Richmond A (2014) Biomicrofluidics 8(4): 044105
    › Primary publication · 25379090 (PubMed) · PMC4189212 (PubMed Central)
  3. Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia. Brown JA, Sherrod SD, Goodwin CR, Brewer B, Yang L, Garbett KA, Li D, McLean JA, Wikswo JP, Mirnics K (2014) J Neuroinflammation : 183
    › Primary publication · 25374324 (PubMed) · PMC4233071 (PubMed Central)
  4. Multichamber Multipotentiostat System for Cellular Microphysiometry. Lima EA, Snider RM, Reiserer RS, McKenzie JR, Kimmel DW, Eklund SE, Wikswo JP, Cliffel DE (2014) Sens Actuators B Chem : 536-543
    › Primary publication · 25242863 (PubMed) · PMC4167374 (PubMed Central)
  5. The relevance and potential roles of microphysiological systems in biology and medicine. Wikswo JP (2014) Exp Biol Med (Maywood) 239(9): 1061-72
    › Primary publication · 25187571 (PubMed) · PMC4330974 (PubMed Central)
  6. Systems-level view of cocaine addiction: the interconnection of the immune and nervous systems. Marasco CC, Goodwin CR, Winder DG, Schramm-Sapyta NL, McLean JA, Wikswo JP (2014) Exp Biol Med (Maywood) 239(11): 1433-42
    › Primary publication · 24903164 (PubMed) · PMC4216763 (PubMed Central)
  7. The microfluidic multitrap nanophysiometer for hematologic cancer cell characterization reveals temporal sensitivity of the calcein-AM efflux assay. Byrd TF, Hoang LT, Kim EG, Pfister ME, Werner EM, Arndt SE, Chamberlain JW, Hughey JJ, Nguyen BA, Schneibel EJ, Wertz LL, Whitfield JS, Wikswo JP, Seale KT (2014) Sci Rep : 5117
    › Primary publication · 24873950 (PubMed) · PMC4038811 (PubMed Central)
  8. Techniques and assays for the study of angiogenesis. Irvin MW, Zijlstra A, Wikswo JP, Pozzi A (2014) Exp Biol Med (Maywood) 239(11): 1476-88
    › Primary publication · 24872440 (PubMed) · PMC4216737 (PubMed Central)
  9. Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data. Goodwin CR, Sherrod SD, Marasco CC, Bachmann BO, Schramm-Sapyta N, Wikswo JP, McLean JA (2014) Anal Chem 86(13): 6563-71
    › Primary publication · 24856386 (PubMed) · PMC4082383 (PubMed Central)
  10. Neurovascular unit on a chip: implications for translational applications. Alcendor DJ, Block FE, Cliffel DE, Daniels JS, Ellacott KL, Goodwin CR, Hofmeister LH, Li D, Markov DA, May JC, McCawley LJ, McLaughlin B, McLean JA, Niswender KD, Pensabene V, Seale KT, Sherrod SD, Sung HJ, Tabb DL, Webb DJ, Wikswo JP (2013) Stem Cell Res Ther : S18
    › Primary publication · 24564885 (PubMed) · PMC4029462 (PubMed Central)
  11. A microfluidic-enabled mechanical microcompressor for the immobilization of live single- and multi-cellular specimens. Yan Y, Jiang L, Aufderheide KJ, Wright GA, Terekhov A, Costa L, Qin K, McCleery WT, Fellenstein JJ, Ustione A, Robertson JB, Johnson CH, Piston DW, Hutson MS, Wikswo JP, Hofmeister W, Janetopoulos C (2014) Microsc Microanal 20(1): 141-51
    › Primary publication · 24444078 (PubMed) · PMC4026272 (PubMed Central)
  12. Cryogenic Etching of Silicon: An Alternative Method For Fabrication of Vertical Microcantilever Master Molds. Addae-Mensah KA, Retterer S, Opalenik SR, Thomas D, Lavrik NV, Wikswo JP (2009) J Microelectromech Syst 19(1)
    › Primary publication · 24223478 (PubMed) · PMC3818692 (PubMed Central)
  13. Mechanistic analysis of challenge-response experiments. Shotwell MS, Drake KJ, Sidorov VY, Wikswo JP (2013) Biometrics 69(3): 741-7
    › Primary publication · 23859366 (PubMed) · PMC4156014 (PubMed Central)
  14. Grand challenges in interfacing engineering with life sciences and medicine. He B, Baird R, Butera R, Datta A, George S, Hecht B, Hero A, Lazzi G, Lee RC, Liang J, Neuman M, Peng GC, Perreault EJ, Ramasubramanian M, Wang MD, Wikswo J, Yang GZ, Zhang YT (2013) IEEE Trans Biomed Eng 60(3): 589-98
    › Primary publication · 23380847 (PubMed)
  15. Amino acids as metabolic substrates during cardiac ischemia. Drake KJ, Sidorov VY, McGuinness OP, Wasserman DH, Wikswo JP (2012) Exp Biol Med (Maywood) 237(12): 1369-78
    › Primary publication · 23354395 (PubMed) · PMC3816490 (PubMed Central)
  16. Quantification of transmembrane currents during action potential propagation in the heart. Gray RA, Mashburn DN, Sidorov VY, Wikswo JP (2013) Biophys J 104(1): 268-78
    › Primary publication · 23332079 (PubMed) · PMC3540262 (PubMed Central)
  17. Metabolic discrimination of select list agents by monitoring cellular responses in a multianalyte microphysiometer. Eklund SE, Thompson RG, Snider RM, Carney CK, Wright DW, Wikswo J, Cliffel DE (2009) Sensors (Basel) 9(3): 2117-33
    › Primary publication · 22574003 (PubMed) · PMC3345856 (PubMed Central)
  18. CellAnimation: an open source MATLAB framework for microscopy assays. Georgescu W, Wikswo JP, Quaranta V (2012) Bioinformatics 28(1): 138-9
    › Primary publication · 22121157 (PubMed) · PMC3244774 (PubMed Central)
  19. The effects of cholera toxin on cellular energy metabolism. Snider RM, McKenzie JR, Kraft L, Kozlov E, Wikswo JP, Cliffel DE (2010) Toxins (Basel) 2(4): 632-48
    › Primary publication · 22069603 (PubMed) · PMC3153216 (PubMed Central)
  20. Automated refinement and inference of analytical models for metabolic networks. Schmidt MD, Vallabhajosyula RR, Jenkins JW, Hood JE, Soni AS, Wikswo JP, Lipson H (2011) Phys Biol 8(5): 055011
    › Primary publication · 21832805 (PubMed) · PMC4109817 (PubMed Central)
  21. Cardiovascular disease: several small shocks beat one big one. Gray RA, Wikswo JP (2011) Nature 475(7355): 181-2
    › Primary publication · 21753846 (PubMed)
  22. Microfabricated scaffold-guided endothelial morphogenesis in three-dimensional culture. Liu Y, Markov DA, Wikswo JP, McCawley LJ (2011) Biomed Microdevices 13(5): 837-46
    › Primary publication · 21710371 (PubMed)
  23. How do control-based approaches enter into biology? LeDuc PR, Messner WC, Wikswo JP (2011) Annu Rev Biomed Eng : 369-96
    › Primary publication · 21599491 (PubMed)
  24. External control of the GAL network in S. cerevisiae: a view from control theory. Yang R, Lenaghan SC, Wikswo JP, Zhang M (2011) PLoS One 6(4): e19353
    › Primary publication · 21559408 (PubMed) · PMC3084829 (PubMed Central)
  25. Regional increase of extracellular potassium leads to electrical instability and reentry occurrence through the spatial heterogeneity of APD restitution. Sidorov VY, Uzelac I, Wikswo JP (2011) Am J Physiol Heart Circ Physiol 301(1): H209-20
    › Primary publication · 21536842 (PubMed) · PMC3129923 (PubMed Central)
  26. Single-nanocrystal spectroscopy of white-light-emitting CdSe nanocrystals. Dukes AD, Samson PC, Keene JD, Davis LM, Wikswo JP, Rosenthal SJ (2011) J Phys Chem A 115(16): 4076-81
    › Primary publication · 21338163 (PubMed)
  27. A metering rotary nanopump for microfluidic systems. Darby SG, Moore MR, Friedlander TA, Schaffer DK, Reiserer RS, Wikswo JP, Seale KT (2010) Lab Chip 10(23): 3218-26
    › Primary publication · 20959938 (PubMed) · PMC4156019 (PubMed Central)
  28. Open access microfluidic device for the study of cell migration during chemotaxis. Jowhar D, Wright G, Samson PC, Wikswo JP, Janetopoulos C (2010) Integr Biol (Camb) 2(11-12): 648-58
    › Primary publication · 20949221 (PubMed) · PMC3806978 (PubMed Central)
  29. Macro to nano: a simple method for transporting cultured cells from milliliter scale to nanoliter scale. Seale KT, Faley SL, Chamberlain J, Wikswo JP (2010) Exp Biol Med (Maywood) 235(6): 777-83
    › Primary publication · 20511682 (PubMed) · PMC4109816 (PubMed Central)
  30. Increased cell migration and plasticity in Nrf2-deficient cancer cell lines. Rachakonda G, Sekhar KR, Jowhar D, Samson PC, Wikswo JP, Beauchamp RD, Datta PK, Freeman ML (2010) Oncogene 29(25): 3703-14
    › Primary publication · 20440267 (PubMed) · PMC2892014 (PubMed Central)
  31. A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease. Ayati BP, Edwards CM, Webb GF, Wikswo JP (2010) Biol Direct : 28
    › Primary publication · 20406449 (PubMed) · PMC2867965 (PubMed Central)
  32. Origin choice and petal loss in the flower garden of spiral wave tip trajectories. Gray RA, Wikswo JP, Otani NF (2009) Chaos 19(3): 033118
    › Primary publication · 19791998 (PubMed) · PMC2748696 (PubMed Central)
  33. Microfluidic single cell arrays to interrogate signalling dynamics of individual, patient-derived hematopoietic stem cells. Faley SL, Copland M, Wlodkowic D, Kolch W, Seale KT, Wikswo JP, Cooper JM (2009) Lab Chip 9(18): 2659-64
    › Primary publication · 19704981 (PubMed)
  34. The potential of dual camera systems for multimodal imaging of cardiac electrophysiology and metabolism. Holcomb MR, Woods MC, Uzelac I, Wikswo JP, Gilligan JM, Sidorov VY (2009) Exp Biol Med (Maywood) 234(11): 1355-73
    › Primary publication · 19657065 (PubMed) · PMC3816393 (PubMed Central)
  35. Partial independence of bioelectric and biomagnetic fields and its implications for encephalography and cardiography. Irimia A, Swinney KR, Wikswo JP (2009) Phys Rev E Stat Nonlin Soft Matter Phys 79(5 Pt 1): 051908
    › Primary publication · 19518481 (PubMed) · PMC3818693 (PubMed Central)
  36. Microfluidic single-cell array cytometry for the analysis of tumor apoptosis. Wlodkowic D, Faley S, Zagnoni M, Wikswo JP, Cooper JM (2009) Anal Chem 81(13): 5517-23
    › Primary publication · 19514700 (PubMed) · PMC3816605 (PubMed Central)
  37. Migration of isogenic cell lines quantified by dynamic multivariate analysis of single-cell motility. Harris MP, Kim E, Weidow B, Wikswo JP, Quaranta V (2008) Cell Adh Migr 2(2): 127-36
    › Primary publication · 19271355 (PubMed) · PMC2634586 (PubMed Central)
  38. Universal serial bus powered and controlled isolated constant-current physiological stimulator. Holcomb MR, Bekele RY, Lima EA, Wikswo JP (2008) Rev Sci Instrum 79(12): 126103
    › Primary publication · 19123594 (PubMed) · PMC2736648 (PubMed Central)
  39. Mirrored pyramidal wells for simultaneous multiple vantage point microscopy. Seale KT, Reiserer RS, Markov DA, Ges IA, Wright C, Janetopoulos C, Wikswo JP (2008) J Microsc 232(1): 1-6
    › Primary publication · 19017196 (PubMed) · PMC3789065 (PubMed Central)
  40. Microfluidic platform for real-time signaling analysis of multiple single T cells in parallel. Faley S, Seale K, Hughey J, Schaffer DK, VanCompernolle S, McKinney B, Baudenbacher F, Unutmaz D, Wikswo JP (2008) Lab Chip 8(10): 1700-12
    › Primary publication · 18813394 (PubMed) · PMC4160168 (PubMed Central)
  41. Polarity reversal lowers activation time during diastolic field stimulation of the rabbit ventricles: insights into mechanisms. Maleckar MM, Woods MC, Sidorov VY, Holcomb MR, Mashburn DN, Wikswo JP, Trayanova NA (2008) Am J Physiol Heart Circ Physiol 295(4): H1626-33
    › Primary publication · 18708441 (PubMed) · PMC2593523 (PubMed Central)
  42. 3'-phosphoinositides regulate the coordination of speed and accuracy during chemotaxis. Gruver JS, Wikswo JP, Chung CY (2008) Biophys J 95(8): 4057-67
    › Primary publication · 18676656 (PubMed) · PMC2553113 (PubMed Central)
  43. Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis. Sai J, Raman D, Liu Y, Wikswo J, Richmond A (2008) J Biol Chem 283(39): 26538-47
    › Primary publication · 18662984 (PubMed) · PMC2546539 (PubMed Central)
  44. Effects of unipolar stimulation on voltage and calcium distributions in the isolated rabbit heart. Sidorov VY, Holcomb MR, Woods MC, Gray RA, Wikswo JP (2008) Basic Res Cardiol 103(6): 537-51
    › Primary publication · 18642125 (PubMed) · PMC2742888 (PubMed Central)
  45. Measurement techniques for cellular biomechanics in vitro. Addae-Mensah KA, Wikswo JP (2008) Exp Biol Med (Maywood) 233(7): 792-809
    › Primary publication · 18445766 (PubMed) · PMC4156015 (PubMed Central)
  46. Gastrointestinal arrhythmias are associated with statistically significant fluctuations in systemic information dimension. Irimia A, Wikswo JP (2008) Physiol Meas 29(5): N33-40
    › Primary publication · 18427160 (PubMed)
  47. A microfabricated nanocalorimeter: design, characterization, and chemical calibration. Xu J, Reiserer R, Tellinghuisen J, Wikswo JP, Baudenbacher FJ (2008) Anal Chem 80(8): 2728-33
    › Primary publication · 18351750 (PubMed) · PMC4155943 (PubMed Central)
  48. High-resolution high-speed panoramic cardiac imaging system. Evertson DW, Holcomb MR, Eames MC, Bray MA, Sidorov VY, Xu J, Wingard H, Dobrovolny HM, Woods MC, Gauthier DJ, Wikswo JP (2008) IEEE Trans Biomed Eng 55(3): 1241-3
    › Primary publication · 18334422 (PubMed) · PMC2561274 (PubMed Central)
  49. A phased-array stimulator system for studying planar and curved cardiac activation wavefronts. Abbas RA, Lin SF, Mashburn D, Xu J, Wikswo JP (2008) IEEE Trans Biomed Eng 55(1): 222-9
    › Primary publication · 18232365 (PubMed) · PMC2742885 (PubMed Central)
  50. Model-controlled hydrodynamic focusing to generate multiple overlapping gradients of surface-immobilized proteins in microfluidic devices. Georgescu W, Jourquin J, Estrada L, Anderson AR, Quaranta V, Wikswo JP (2008) Lab Chip 8(2): 238-44
    › Primary publication · 18231661 (PubMed) · PMC4357342 (PubMed Central)
  51. Microfluidic switching system for analyzing chemotaxis responses of wortmannin-inhibited HL-60 cells. Liu Y, Sai J, Richmond A, Wikswo JP (2008) Biomed Microdevices 10(4): 499-507
    › Primary publication · 18205049 (PubMed) · PMC2668251 (PubMed Central)
  52. Protozoan migration in bent microfluidic channels. Wang W, Shor LM, LeBoeuf EJ, Wikswo JP, Taghon GL, Kosson DS (2008) Appl Environ Microbiol 74(6): 1945-9
    › Primary publication · 18165365 (PubMed) · PMC2268297 (PubMed Central)
  53. A high-voltage cardiac stimulator for field shocks of a whole heart in a bath. Mashburn DN, Hinkson SJ, Woods MC, Gilligan JM, Holcomb MR, Wikswo JP (2007) Rev Sci Instrum 78(10): 104302
    › Primary publication · 17979442 (PubMed)