C. Quarles
Faculty Member
Last active: 2/12/2015

Profile

Dr. Quarles's research focuses on the development and validation of multi-modal imaging methods for the non-invasive assessment of cancer and renal pathophysiology. Using MRI, PET and SPECT imaging techniques with and without targeted contrast agents his lab investigates markers of abnormal cancer metabolism, oxygenation status and angiogenesis in pre-clinical models of cancer.

Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Modeling the effect of intra-voxel diffusion of contrast agent on the quantitative analysis of dynamic contrast enhanced magnetic resonance imaging. Barnes SL, Quarles CC, Yankeelov TE (2014) PLoS One 9(9): e108726
    › Primary publication · 25275536 (PubMed) · PMC4183533 (PubMed Central)
  2. Assessing tumor cytoarchitecture using multiecho DSC-MRI derived measures of the transverse relaxivity at tracer equilibrium (TRATE). Semmineh NB, Xu J, Skinner JT, Xie J, Li H, Ayers G, Quarles CC (2015) Magn Reson Med 74(3): 772-84
    › Primary publication · 25227668 (PubMed) · PMC4362846 (PubMed Central)
  3. Evaluation of a multiple spin- and gradient-echo (SAGE) EPI acquisition with SENSE acceleration: applications for perfusion imaging in and outside the brain. Skinner JT, Robison RK, Elder CP, Newton AT, Damon BM, Quarles CC (2014) Magn Reson Imaging 32(10): 1171-80
    › Primary publication · 25179133 (PubMed) · PMC4253546 (PubMed Central)
  4. Assessment of a combined spin- and gradient-echo (SAGE) DSC-MRI method for preclinical neuroimaging. Stokes AM, Skinner JT, Quarles CC (2014) Magn Reson Imaging 32(10): 1181-90
    › Primary publication · 25172987 (PubMed) · PMC4254163 (PubMed Central)
  5. Quantitative multimodality imaging in cancer research and therapy. Yankeelov TE, Abramson RG, Quarles CC (2014) Nat Rev Clin Oncol 11(11): 670-80
    › Primary publication · 25113842 (PubMed) · PMC4909117 (PubMed Central)
  6. Longitudinal assessment of mouse renal injury using high-resolution anatomic and magnetization transfer MR imaging. Wang F, Jiang R, Takahashi K, Gore J, Harris RC, Takahashi T, Quarles CC (2014) Magn Reson Imaging 32(9): 1125-32
    › Primary publication · 25093632 (PubMed) · PMC4171209 (PubMed Central)
  7. Nitrite induces the extravasation of iron oxide nanoparticles in hypoxic tumor tissue. Mistry N, Stokes AM, Gambrell JV, Quarles CC (2014) NMR Biomed 27(4): 425-30
    › Primary publication · 24470164 (PubMed) · PMC3966547 (PubMed Central)
  8. Potential of compressed sensing in quantitative MR imaging of cancer. Smith DS, Li X, Abramson RG, Quarles CC, Yankeelov TE, Welch EB (2013) Cancer Imaging 13(4): 633-44
    › Primary publication · 24434808 (PubMed) · PMC3893904 (PubMed Central)
  9. An efficient computational approach to characterize DSC-MRI signals arising from three-dimensional heterogeneous tissue structures. Semmineh NB, Xu J, Boxerman JL, Delaney GW, Cleary PW, Gore JC, Quarles CC (2014) PLoS One 9(1): e84764
    › Primary publication · 24416281 (PubMed) · PMC3885618 (PubMed Central)
  10. Imaging amide proton transfer and nuclear overhauser enhancement using chemical exchange rotation transfer (CERT). Zu Z, Xu J, Li H, Chekmenev EY, Quarles CC, Does MD, Gore JC, Gochberg DF (2014) Magn Reson Med 72(2): 471-6
    › Primary publication · 24302497 (PubMed) · PMC4401079 (PubMed Central)
  11. Repeatability and sensitivity of high resolution blood volume mapping in mouse kidney disease. Wang F, Jiang RT, Tantawy MN, Borza DB, Takahashi K, Gore JC, Harris RC, Takahashi T, Quarles CC (2014) J Magn Reson Imaging 39(4): 866-71
    › Primary publication · 24006202 (PubMed) · PMC3858530 (PubMed Central)
  12. Assessment of renal function in mice with unilateral ureteral obstruction using 99mTc-MAG3 dynamic scintigraphy. Tantawy MN, Jiang R, Wang F, Takahashi K, Peterson TE, Zemel D, Hao CM, Fujita H, Harris RC, Quarles CC, Takahashi T (2012) BMC Nephrol : 168
    › Primary publication · 23228112 (PubMed) · PMC3542003 (PubMed Central)
  13. Comparison of dual-echo DSC-MRI- and DCE-MRI-derived contrast agent kinetic parameters. Quarles CC, Gore JC, Xu L, Yankeelov TE (2012) Magn Reson Imaging 30(7): 944-53
    › Primary publication · 22617148 (PubMed) · PMC3569857 (PubMed Central)
  14. Robustness of quantitative compressive sensing MRI: the effect of random undersampling patterns on derived parameters for DCE- and DSC-MRI. Smith DS, Li X, Gambrell JV, Arlinghaus LR, Quarles CC, Yankeelov TE, Welch EB (2012) IEEE Trans Med Imaging 31(2): 504-11
    › Primary publication · 22010146 (PubMed) · PMC3289060 (PubMed Central)
  15. Enzastaurin (LY317615), a protein kinase C beta selective inhibitor, enhances antiangiogenic effect of radiation. Willey CD, Xiao D, Tu T, Kim KW, Moretti L, Niermann KJ, Tawtawy MN, Quarles CC, Lu B (2010) Int J Radiat Oncol Biol Phys 77(5): 1518-26
    › Primary publication · 19906497 (PubMed) · PMC3688843 (PubMed Central)
  16. A theoretical framework to model DSC-MRI data acquired in the presence of contrast agent extravasation. Quarles CC, Gochberg DF, Gore JC, Yankeelov TE (2009) Phys Med Biol 54(19): 5749-66
    › Primary publication · 19729712 (PubMed) · PMC2767268 (PubMed Central)