Pierre Massion
Faculty Member
Last active: 1/11/2018

Pierre P Massion, M.D.

Official Affiliation: Medicine

Profile

  1. Role of chromosome 3q in lung cancer. Selection of candidate genes driving a genomic amplicon on Chromosome 3q. Focus on functional genomics for candidate driver genes on chromosome 3q such as p63 and PIK3CA. RO1 funded.
  2. Proteomic approach to preinvasive lung cancer. Protein profiling of preinvasive lesions in bronchial biopsy and invasive lung cancer by MALDI MS; Identification of discriminatory proteins by LC-MSMS proteomics; Image analysis. funded by RO1 and SPORE in lung cancer.
  3. Lung cancer biomarker discovery and validation. Identification of discriminatory proteins between lung cancer and controls after multidimensional mass spectrometry analysis of biological specimen and Phage-display recombinant antibody library (serum, plasma or pleural fluid). Funded by Vanderbilt SPORE in lung cancer, VA Merit review grant, ASCO research award and EDRN Clinical Validation Center (U01).
  4. Inflammation and cancer. We are working on 3 proteins. PPAR delta in lung tumorigenesis (Pedchenko, 2008), Role of serum amyloid A in regulating apoptosis in lung cancer cells, and pIgR as a potential tumor suppressor gene in lung cancer (Polosukhin, 2007). Work supported by Damon Runyon Foundation and a Vanderbilt Discovery Grant.

Please visit our website at https://www.vumc.org/massion-lab/.

Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Communication About the Probability of Cancer in Indeterminate Pulmonary Nodules. Maiga AW, Deppen SA, Massion PP, Callaway-Lane C, Pinkerman R, Dittus RS, Lambright ES, Nesbitt JC, Grogan EL (2018) JAMA Surg 153(4): 353-357
    › Primary publication · 29261826 (PubMed) · PMC5910256 (PubMed Central)
  2. Intracardiac Metastases Detected by 18F-FSPG PET/CT. Magarik MA, Walker RC, Gilbert J, Manning HC, Massion PP (2018) Clin Nucl Med 43(1): 28-30
    › Primary publication · 29076915 (PubMed) · PMC5716866 (PubMed Central)
  3. Timeliness of Care and Lung Cancer Tumor-Stage Progression: How Long Can We Wait? Maiga AW, Deppen SA, Pinkerman R, Callaway-Lane C, Massion PP, Dittus RS, Lambright ES, Nesbitt JC, Baker D, Grogan EL (2017) Ann Thorac Surg 104(6): 1791-1797
    › Primary publication · 29033012 (PubMed) · PMC5813822 (PubMed Central)
  4. Evaluating Molecular Biomarkers for the Early Detection of Lung Cancer: When Is a Biomarker Ready for Clinical Use? An Official American Thoracic Society Policy Statement. Mazzone PJ, Sears CR, Arenberg DA, Gaga M, Gould MK, Massion PP, Nair VS, Powell CA, Silvestri GA, Vachani A, Wiener RS, ATS Assembly on Thoracic Oncology (2017) Am J Respir Crit Care Med 196(7): e15-e29
    › Primary publication · 28960111 (PubMed) · PMC5803661 (PubMed Central)
  5. Identification of Proteomic Features To Distinguish Benign Pulmonary Nodules from Lung Adenocarcinoma. Codreanu SG, Hoeksema MD, Slebos RJC, Zimmerman LJ, Rahman SMJ, Li M, Chen SC, Chen H, Eisenberg R, Liebler DC, Massion PP (2017) J Proteome Res 16(9): 3266-3276
    › Primary publication · 28731711 (PubMed) · PMC6339813 (PubMed Central)
  6. Single Cell Analysis of Human Tissues and Solid Tumors with Mass Cytometry. Leelatian N, Doxie DB, Greenplate AR, Mobley BC, Lehman JM, Sinnaeve J, Kauffman RM, Werkhaven JA, Mistry AM, Weaver KD, Thompson RC, Massion PP, Hooks MA, Kelley MC, Chambless LB, Ihrie RA, Irish JM (2017) Cytometry B Clin Cytom
    › Primary publication · 28719730 (PubMed)
  7. Immunotherapy and Targeted Therapy for Small Cell Lung Cancer: There Is Hope. Lehman JM, Gwin ME, Massion PP (2017) Curr Oncol Rep 19(7): 49
    › Primary publication · 28643173 (PubMed)
  8. A 3q gene signature associated with triple negative breast cancer organ specific metastasis and response to neoadjuvant chemotherapy. Qian J, Chen H, Ji X, Eisenberg R, Chakravarthy AB, Mayer IA, Massion PP (2017) Sci Rep : 45828
    › Primary publication · 28387221 (PubMed) · PMC5384279 (PubMed Central)
  9. Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis. Gardner EE, Lok BH, Schneeberger VE, Desmeules P, Miles LA, Arnold PK, Ni A, Khodos I, de Stanchina E, Nguyen T, Sage J, Campbell JE, Ribich S, Rekhtman N, Dowlati A, Massion PP, Rudin CM, Poirier JT (2017) Cancer Cell 31(2): 286-299
    › Primary publication · 28196596 (PubMed) · PMC5313262 (PubMed Central)
  10. 68Ga-DOTATATE PET/CT imaging of indeterminate pulmonary nodules and lung cancer. Walker R, Deppen S, Smith G, Shi C, Lehman J, Clanton J, Moore B, Burns R, Grogan EL, Massion PP (2017) PLoS One 12(2): e0171301
    › Primary publication · 28182730 (PubMed) · PMC5300187 (PubMed Central)
  11. Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity. Udyavar AR, Wooten DJ, Hoeksema M, Bansal M, Califano A, Estrada L, Schnell S, Irish JM, Massion PP, Quaranta V (2017) Cancer Res 77(5): 1063-1074
    › Primary publication · 27932399 (PubMed) · PMC5532541 (PubMed Central)
  12. Secretory IgA Deficiency in Individual Small Airways Is Associated with Persistent Inflammation and Remodeling. Polosukhin VV, Richmond BW, Du RH, Cates JM, Wu P, Nian H, Massion PP, Ware LB, Lee JW, Kononov AV, Lawson WE, Blackwell TS (2017) Am J Respir Crit Care Med 195(8): 1010-1021
    › Primary publication · 27911098 (PubMed) · PMC5422646 (PubMed Central)
  13. The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer. Rahman SMJ, Ji X, Zimmerman LJ, Li M, Harris BK, Hoeksema MD, Trenary IA, Zou Y, Qian J, Slebos RJ, Beane J, Spira A, Shyr Y, Eisenberg R, Liebler DC, Young JD, Massion PP (2016) JCI Insight 1(19): e88814
    › Primary publication · 27882349 (PubMed) · PMC5111517 (PubMed Central)
  14. The Pursuit of Noninvasive Diagnosis of Lung Cancer. Atwater T, Cook CM, Massion PP (2016) Semin Respir Crit Care Med 37(5): 670-680
    › Primary publication · 27732989 (PubMed) · PMC5317274 (PubMed Central)
  15. Radiological Image Traits Predictive of Cancer Status in Pulmonary Nodules. Liu Y, Balagurunathan Y, Atwater T, Antic S, Li Q, Walker RC, Smith GT, Massion PP, Schabath MB, Gillies RJ (2017) Clin Cancer Res 23(6): 1442-1449
    › Primary publication · 27663588 (PubMed) · PMC5527551 (PubMed Central)
  16. Autoantibody Signature Enhances the Positive Predictive Power of Computed Tomography and Nodule-Based Risk Models for Detection of Lung Cancer. Massion PP, Healey GF, Peek LJ, Fredericks L, Sewell HF, Murray A, Robertson JF (2017) J Thorac Oncol 12(3): 578-584
    › Primary publication · 27615397 (PubMed) · PMC5367043 (PubMed Central)
  17. Single cell analysis of human tissues and solid tumors with mass cytometry. Leelatian N, Doxie DB, Greenplate AR, Mobley BC, Lehman JM, Sinnaeve J, Kauffmann RM, Werkhaven JA, Mistry AM, Weaver KD, Thompson RC, Massion PP, Hooks MA, Kelley MC, Chambless LB, Ihrie RA, Irish JM (2017) Cytometry B Clin Cytom 92(1): 68-78
    › Primary publication · 27598832 (PubMed) · PMC5459378 (PubMed Central)
  18. Fluorescence-based measurement of cystine uptake through xCT shows requirement for ROS detoxification in activated lymphocytes. Siska PJ, Kim B, Ji X, Hoeksema MD, Massion PP, Beckermann KE, Wu J, Chi JT, Hong J, Rathmell JC (2016) J Immunol Methods : 51-58
    › Primary publication · 27594594 (PubMed) · PMC5065394 (PubMed Central)
  19. Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis. Boutaud O, Sosa IR, Amin T, Oram D, Adler D, Hwang HS, Crews BC, Milne G, Harris BK, Hoeksema M, Knollmann BC, Lammers PE, Marnett LJ, Massion PP, Oates JA (2016) Cancer Prev Res (Phila) 9(11): 855-865
    › Primary publication · 27554763 (PubMed) · PMC5093073 (PubMed Central)
  20. Differences in Patient Outcomes of Prevalence, Interval, and Screen-Detected Lung Cancers in the CT Arm of the National Lung Screening Trial. Schabath MB, Massion PP, Thompson ZJ, Eschrich SA, Balagurunathan Y, Goldof D, Aberle DR, Gillies RJ (2016) PLoS One 11(8): e0159880
    › Primary publication · 27509046 (PubMed) · PMC4980050 (PubMed Central)
  21. Biomarkers of risk to develop lung cancer in the new screening era. Atwater T, Massion PP (2016) Ann Transl Med 4(8): 158
    › Primary publication · 27195276 (PubMed) · PMC4860477 (PubMed Central)
  22. Accumulation of isolevuglandin-modified protein in normal and fibrotic lung. Mont S, Davies SS, Roberts Second LJ, Mernaugh RL, McDonald WH, Segal BH, Zackert W, Kropski JA, Blackwell TS, Sekhar KR, Galligan JJ, Massion PP, Marnett LJ, Travis EL, Freeman ML (2016) Sci Rep : 24919
    › Primary publication · 27118599 (PubMed) · PMC4847119 (PubMed Central)
  23. Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes? Bunn PA, Minna JD, Augustyn A, Gazdar AF, Ouadah Y, Krasnow MA, Berns A, Brambilla E, Rekhtman N, Massion PP, Niederst M, Peifer M, Yokota J, Govindan R, Poirier JT, Byers LA, Wynes MW, McFadden DG, MacPherson D, Hann CL, Farago AF, Dive C, Teicher BA, Peacock CD, Johnson JE, Cobb MH, Wendel HG, Spigel D, Sage J, Yang P, Pietanza MC, Krug LM, Heymach J, Ujhazy P, Zhou C, Goto K, Dowlati A, Christensen CL, Park K, Einhorn LH, Edelman MJ, Giaccone G, Gerber DE, Salgia R, Owonikoko T, Malik S, Karachaliou N, Gandara DR, Slotman BJ, Blackhall F, Goss G, Thomas R, Rudin CM, Hirsch FR (2016) J Thorac Oncol 11(4): 453-74
    › Primary publication · 26829312 (PubMed) · PMC4836290 (PubMed Central)
  24. Lung cancer risk test trial: study design, participant baseline characteristics, bronchoscopy safety, and establishment of a biospecimen repository. Crawford EL, Levin A, Safi F, Lu M, Baugh A, Zhang X, Yeo J, Khuder SA, Boulos AM, Nana-Sinkam P, Massion PP, Arenberg DA, Midthun D, Mazzone PJ, Nathan SD, Wainz R, Silvestri G, Tita J, Willey JC (2016) BMC Pulm Med : 16
    › Primary publication · 26801409 (PubMed) · PMC4722707 (PubMed Central)
  25. Global gene expression profiling reveals a suppressed immune response pathway associated with 3q amplification in squamous carcinoma of the lung. Qian J, Zou Y, Wang J, Zhang B, Massion PP (2015) Genom Data : 272-4
    › Primary publication · 26484266 (PubMed) · PMC4583673 (PubMed Central)
  26. Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease. Du RH, Richmond BW, Blackwell TS, Cates JM, Massion PP, Ware LB, Lee JW, Kononov AV, Lawson WE, Blackwell TS, Polosukhin VV (2015) Virchows Arch 467(6): 657-665
    › Primary publication · 26432569 (PubMed) · PMC5081073 (PubMed Central)
  27. Reproducibility of Volumetric Computed Tomography of Stable Small Pulmonary Nodules with Implications on Estimated Growth Rate and Optimal Scan Interval. Smith GT, Rahman AR, Li M, Moore B, Gietema H, Veronesi G, Massion PP, Walker RC (2015) PLoS One 10(9): e0138144
    › Primary publication · 26379272 (PubMed) · PMC4575025 (PubMed Central)
  28. A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo. Saunders LR, Bankovich AJ, Anderson WC, Aujay MA, Bheddah S, Black K, Desai R, Escarpe PA, Hampl J, Laysang A, Liu D, Lopez-Molina J, Milton M, Park A, Pysz MA, Shao H, Slingerland B, Torgov M, Williams SA, Foord O, Howard P, Jassem J, Badzio A, Czapiewski P, Harpole DH, Dowlati A, Massion PP, Travis WD, Pietanza MC, Poirier JT, Rudin CM, Stull RA, Dylla SJ (2015) Sci Transl Med 7(302): 302ra136
    › Primary publication · 26311731 (PubMed) · PMC4934375 (PubMed Central)
  29. Comprehensive genomic profiles of small cell lung cancer. George J, Lim JS, Jang SJ, Cun Y, Ozretić L, Kong G, Leenders F, Lu X, Fernández-Cuesta L, Bosco G, Müller C, Dahmen I, Jahchan NS, Park KS, Yang D, Karnezis AN, Vaka D, Torres A, Wang MS, Korbel JO, Menon R, Chun SM, Kim D, Wilkerson M, Hayes N, Engelmann D, Pützer B, Bos M, Michels S, Vlasic I, Seidel D, Pinther B, Schaub P, Becker C, Altmüller J, Yokota J, Kohno T, Iwakawa R, Tsuta K, Noguchi M, Muley T, Hoffmann H, Schnabel PA, Petersen I, Chen Y, Soltermann A, Tischler V, Choi CM, Kim YH, Massion PP, Zou Y, Jovanovic D, Kontic M, Wright GM, Russell PA, Solomon B, Koch I, Lindner M, Muscarella LA, la Torre A, Field JK, Jakopovic M, Knezevic J, Castaños-Vélez E, Roz L, Pastorino U, Brustugun OT, Lund-Iversen M, Thunnissen E, Köhler J, Schuler M, Botling J, Sandelin M, Sanchez-Cespedes M, Salvesen HB, Achter V, Lang U, Bogus M, Schneider PM, Zander T, Ansén S, Hallek M, Wolf J, Vingron M, Yatabe Y, Travis WD, Nürnberg P, Reinhardt C, Perner S, Heukamp L, Büttner R, Haas SA, Brambilla E, Peifer M, Sage J, Thomas RK (2015) Nature 524(7563): 47-53
    › Primary publication · 26168399 (PubMed) · PMC4861069 (PubMed Central)
  30. Preclinical Evaluation of 4-[18F]Fluoroglutamine PET to Assess ASCT2 Expression in Lung Cancer. Hassanein M, Hight MR, Buck JR, Tantawy MN, Nickels ML, Hoeksema MD, Harris BK, Boyd K, Massion PP, Manning HC (2016) Mol Imaging Biol 18(1): 18-23
    › Primary publication · 25971659 (PubMed) · PMC4644503 (PubMed Central)
  31. Targeting SLC1a5-mediated glutamine dependence in non-small cell lung cancer. Hassanein M, Qian J, Hoeksema MD, Wang J, Jacobovitz M, Ji X, Harris FT, Harris BK, Boyd KL, Chen H, Eisenberg R, Massion PP (2015) Int J Cancer 137(7): 1587-97
    › Primary publication · 25821004 (PubMed) · PMC4640891 (PubMed Central)
  32. Chronic obstructive pulmonary disease and subsequent overall and lung cancer mortality in low-income adults. Aldrich MC, Munro HM, Mumma M, Grogan EL, Massion PP, Blackwell TS, Blot WJ (2015) PLoS One 10(3): e0121805
    › Primary publication · 25811837 (PubMed) · PMC4374870 (PubMed Central)
  33. The RNA binding protein FXR1 is a new driver in the 3q26-29 amplicon and predicts poor prognosis in human cancers. Qian J, Hassanein M, Hoeksema MD, Harris BK, Zou Y, Chen H, Lu P, Eisenberg R, Wang J, Espinosa A, Ji X, Harris FT, Rahman SM, Massion PP (2015) Proc Natl Acad Sci U S A 112(11): 3469-74
    › Primary publication · 25733852 (PubMed) · PMC4371932 (PubMed Central)
  34. Somatostatin Receptors in Lung Cancer: From Function to Molecular Imaging and Therapeutics. Callison JC, Walker RC, Massion PP (2011) J Lung Cancer 10(2): 69-76
    › Primary publication · 25663834 (PubMed) · PMC4319675 (PubMed Central)
  35. Validation of a multiprotein plasma classifier to identify benign lung nodules. Vachani A, Pass HI, Rom WN, Midthun DE, Edell ES, Laviolette M, Li XJ, Fong PY, Hunsucker SW, Hayward C, Mazzone PJ, Madtes DK, Miller YE, Walker MG, Shi J, Kearney P, Fang KC, Massion PP (2015) J Thorac Oncol 10(4): 629-37
    › Primary publication · 25590604 (PubMed) · PMC4382127 (PubMed Central)
  36. Lung cancer screening, version 1.2015: featured updates to the NCCN guidelines. Wood DE, Kazerooni E, Baum SL, Dransfield MT, Eapen GA, Ettinger DS, Hou L, Jackman DM, Klippenstein D, Kumar R, Lackner RP, Leard LE, Leung AN, Makani SS, Massion PP, Meyers BF, Otterson GA, Peairs K, Pipavath S, Pratt-Pozo C, Reddy C, Reid ME, Rotter AJ, Sachs PB, Schabath MB, Sequist LV, Tong BC, Travis WD, Yang SC, Gregory KM, Hughes M, National comprehension cancer network (2015) J Natl Compr Canc Netw 13(1): 23-34; quiz 34
    › Primary publication · 25583767 (PubMed)
  37. Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease. Kropski JA, Pritchett JM, Zoz DF, Crossno PF, Markin C, Garnett ET, Degryse AL, Mitchell DB, Polosukhin VV, Rickman OB, Choi L, Cheng DS, McConaha ME, Jones BR, Gleaves LA, McMahon FB, Worrell JA, Solus JF, Ware LB, Lee JW, Massion PP, Zaynagetdinov R, White ES, Kurtis JD, Johnson JE, Groshong SD, Lancaster LH, Young LR, Steele MP, Phillips Iii JA, Cogan JD, Loyd JE, Lawson WE, Blackwell TS (2015) Am J Respir Crit Care Med 191(4): 417-26
    › Primary publication · 25389906 (PubMed) · PMC4351594 (PubMed Central)
  38. Indeterminate pulmonary nodules: risk for having or for developing lung cancer? Massion PP, Walker RC (2014) Cancer Prev Res (Phila) 7(12): 1173-8
    › Primary publication · 25348855 (PubMed) · PMC4829944 (PubMed Central)
  39. Accuracy of FDG-PET to diagnose lung cancer in areas with infectious lung disease: a meta-analysis. Deppen SA, Blume JD, Kensinger CD, Morgan AM, Aldrich MC, Massion PP, Walker RC, McPheeters ML, Putnam JB, Grogan EL (2014) JAMA 312(12): 1227-36
    › Primary publication · 25247519 (PubMed) · PMC4315183 (PubMed Central)
  40. Predicting lung cancer prior to surgical resection in patients with lung nodules. Deppen SA, Blume JD, Aldrich MC, Fletcher SA, Massion PP, Walker RC, Chen HC, Speroff T, Degesys CA, Pinkerman R, Lambright ES, Nesbitt JC, Putnam JB, Grogan EL (2014) J Thorac Oncol 9(10): 1477-84
    › Primary publication · 25170644 (PubMed) · PMC4272613 (PubMed Central)
  41. Blockade of the programmed death-1 pathway restores sarcoidosis CD4(+) T-cell proliferative capacity. Braun NA, Celada LJ, Herazo-Maya JD, Abraham S, Shaginurova G, Sevin CM, Grutters J, Culver DA, Dworski R, Sheller J, Massion PP, Polosukhin VV, Johnson JE, Kaminski N, Wilkes DS, Oswald-Richter KA, Drake WP (2014) Am J Respir Crit Care Med 190(5): 560-71
    › Primary publication · 25073001 (PubMed) · PMC4214083 (PubMed Central)
  42. Toward rapid, high-sensitivity, volume-constrained biomarker quantification and validation using backscattering interferometry. Olmsted IR, Hassanein M, Kussrow A, Hoeksema M, Li M, Massion PP, Bornhop DJ (2014) Anal Chem 86(15): 7566-74
    › Primary publication · 24954171 (PubMed) · PMC4215853 (PubMed Central)
  43. Lung cancer screening and smoking cessation: a teachable moment? Deppen SA, Grogan EL, Aldrich MC, Massion PP (2014) J Natl Cancer Inst 106(6): dju122
    › Primary publication · 24872542 (PubMed) · PMC5073840 (PubMed Central)
  44. Acyl-coenzyme A-binding protein regulates Beta-oxidation required for growth and survival of non-small cell lung cancer. Harris FT, Rahman SM, Hassanein M, Qian J, Hoeksema MD, Chen H, Eisenberg R, Chaurand P, Caprioli RM, Shiota M, Massion PP (2014) Cancer Prev Res (Phila) 7(7): 748-57
    › Primary publication · 24819876 (PubMed) · PMC4090029 (PubMed Central)
  45. Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer. Udyavar AR, Hoeksema MD, Clark JE, Zou Y, Tang Z, Li Z, Li M, Chen H, Statnikov A, Shyr Y, Liebler DC, Field J, Eisenberg R, Estrada L, Massion PP, Quaranta V (2013) BMC Syst Biol : S1
    › Primary publication · 24564859 (PubMed) · PMC4029366 (PubMed Central)
  46. Discovery of new membrane-associated proteins overexpressed in small-cell lung cancer. Ocak S, Friedman DB, Chen H, Ausborn JA, Hassanein M, Detry B, Weynand B, Aboubakar F, Pilette C, Sibille Y, Massion PP (2014) J Thorac Oncol 9(3): 324-36
    › Primary publication · 24518087 (PubMed) · PMC4028683 (PubMed Central)
  47. Biomarkers to the rescue in a lung nodule epidemic. Massion PP (2014) J Clin Oncol 32(8): 725-6
    › Primary publication · 24516023 (PubMed)
  48. A blood-based proteomic classifier for the molecular characterization of pulmonary nodules. Li XJ, Hayward C, Fong PY, Dominguez M, Hunsucker SW, Lee LW, McLean M, Law S, Butler H, Schirm M, Gingras O, Lamontagne J, Allard R, Chelsky D, Price ND, Lam S, Massion PP, Pass H, Rom WN, Vachani A, Fang KC, Hood L, Kearney P (2013) Sci Transl Med 5(207): 207ra142
    › Primary publication · 24132637 (PubMed) · PMC4114963 (PubMed Central)
  49. Tumour angiogenesis regulation by the miR-200 family. Pecot CV, Rupaimoole R, Yang D, Akbani R, Ivan C, Lu C, Wu S, Han HD, Shah MY, Rodriguez-Aguayo C, Bottsford-Miller J, Liu Y, Kim SB, Unruh A, Gonzalez-Villasana V, Huang L, Zand B, Moreno-Smith M, Mangala LS, Taylor M, Dalton HJ, Sehgal V, Wen Y, Kang Y, Baggerly KA, Lee JS, Ram PT, Ravoori MK, Kundra V, Zhang X, Ali-Fehmi R, Gonzalez-Angulo AM, Massion PP, Calin GA, Lopez-Berestein G, Zhang W, Sood AK (2013) Nat Commun : 2427
    › Primary publication · 24018975 (PubMed) · PMC3904438 (PubMed Central)
  50. Investigation of complement activation product c4d as a diagnostic and prognostic biomarker for lung cancer. Ajona D, Pajares MJ, Corrales L, Perez-Gracia JL, Agorreta J, Lozano MD, Torre W, Massion PP, de-Torres JP, Jantus-Lewintre E, Camps C, Zulueta JJ, Montuenga LM, Pio R (2013) J Natl Cancer Inst 105(18): 1385-93
    › Primary publication · 23940286 (PubMed) · PMC3776260 (PubMed Central)
  51. Integrative genomics analysis identifies candidate drivers at 3q26-29 amplicon in squamous cell carcinoma of the lung. Wang J, Qian J, Hoeksema MD, Zou Y, Espinosa AV, Rahman SM, Zhang B, Massion PP (2013) Clin Cancer Res 19(20): 5580-90
    › Primary publication · 23908357 (PubMed) · PMC3807802 (PubMed Central)
  52. Membrane versus soluble isoforms of TNF-α exert opposing effects on tumor growth and survival of tumor-associated myeloid cells. Ardestani S, Li B, Deskins DL, Wu H, Massion PP, Young PP (2013) Cancer Res 73(13): 3938-50
    › Primary publication · 23704210 (PubMed) · PMC3702680 (PubMed Central)
  53. ALDH7A1 expression is associated with recurrence in patients with surgically resected non-small-cell lung carcinoma. Giacalone NJ, Den RB, Eisenberg R, Chen H, Olson SJ, Massion PP, Carbone DP, Lu B (2013) Future Oncol 9(5): 737-45
    › Primary publication · 23647301 (PubMed) · PMC5341386 (PubMed Central)
  54. Early detection of NSCLC with scFv selected against IgM autoantibody. Pedchenko T, Mernaugh R, Parekh D, Li M, Massion PP (2013) PLoS One 8(4): e60934
    › Primary publication · 23585862 (PubMed) · PMC3621672 (PubMed Central)
  55. Biomarkers and molecular testing for early detection, diagnosis, and therapeutic prediction of lung cancer. Pass HI, Beer DG, Joseph S, Massion P (2013) Thorac Surg Clin 23(2): 211-24
    › Primary publication · 23566973 (PubMed)
  56. SLC1A5 mediates glutamine transport required for lung cancer cell growth and survival. Hassanein M, Hoeksema MD, Shiota M, Qian J, Harris BK, Chen H, Clark JE, Alborn WE, Eisenberg R, Massion PP (2013) Clin Cancer Res 19(3): 560-70
    › Primary publication · 23213057 (PubMed) · PMC3697078 (PubMed Central)
  57. Smoking induces epithelial-to-mesenchymal transition in non-small cell lung cancer through HDAC-mediated downregulation of E-cadherin. Nagathihalli NS, Massion PP, Gonzalez AL, Lu P, Datta PK (2012) Mol Cancer Ther 11(11): 2362-72
    › Primary publication · 22933707 (PubMed) · PMC3969334 (PubMed Central)
  58. Poor survival for veterans with pathologic stage I non-small-cell lung cancer. St Julien JB, Pinkerman R, Aldrich MC, Chen H, Deppen SA, Callaway-Lane C, Massion P, Putnam JB, Lambright ES, Nesbitt JC, Grogan EL (2012) Am J Surg 204(5): 637-42
    › Primary publication · 22906246 (PubMed) · PMC3766956 (PubMed Central)
  59. In-depth proteomic analysis of nonsmall cell lung cancer to discover molecular targets and candidate biomarkers. Kikuchi T, Hassanein M, Amann JM, Liu Q, Slebos RJ, Rahman SM, Kaufman JM, Zhang X, Hoeksema MD, Harris BK, Li M, Shyr Y, Gonzalez AL, Zimmerman LJ, Liebler DC, Massion PP, Carbone DP (2012) Mol Cell Proteomics 11(10): 916-32
    › Primary publication · 22761400 (PubMed) · PMC3494148 (PubMed Central)
  60. Persistent hypocoagulability in patients with septic shock predicts greater hospital mortality: impact of impaired thrombin generation. Massion PB, Peters P, Ledoux D, Zimermann V, Canivet JL, Massion PP, Damas P, Gothot A (2012) Intensive Care Med 38(8): 1326-35
    › Primary publication · 22735856 (PubMed)
  61. The state of molecular biomarkers for the early detection of lung cancer. Hassanein M, Callison JC, Callaway-Lane C, Aldrich MC, Grogan EL, Massion PP (2012) Cancer Prev Res (Phila) 5(8): 992-1006
    › Primary publication · 22689914 (PubMed) · PMC3723112 (PubMed Central)
  62. Added value of a serum proteomic signature in the diagnostic evaluation of lung nodules. Pecot CV, Li M, Zhang XJ, Rajanbabu R, Calitri C, Bungum A, Jett JR, Putnam JB, Callaway-Lane C, Deppen S, Grogan EL, Carbone DP, Worrell JA, Moons KG, Shyr Y, Massion PP (2012) Cancer Epidemiol Biomarkers Prev 21(5): 786-92
    › Primary publication · 22374995 (PubMed) · PMC3660018 (PubMed Central)
  63. Lung cancer screening. Wood DE, Eapen GA, Ettinger DS, Hou L, Jackman D, Kazerooni E, Klippenstein D, Lackner RP, Leard L, Leung AN, Massion PP, Meyers BF, Munden RF, Otterson GA, Peairs K, Pipavath S, Pratt-Pozo C, Reddy C, Reid ME, Rotter AJ, Schabath MB, Sequist LV, Tong BC, Travis WD, Unger M, Yang SC (2012) J Natl Compr Canc Netw 10(2): 240-65
    › Primary publication · 22308518 (PubMed) · PMC6467530 (PubMed Central)
  64. ROS1 rearrangements define a unique molecular class of lung cancers. Bergethon K, Shaw AT, Ou SH, Katayama R, Lovly CM, McDonald NT, Massion PP, Siwak-Tapp C, Gonzalez A, Fang R, Mark EJ, Batten JM, Chen H, Wilner KD, Kwak EL, Clark JW, Carbone DP, Ji H, Engelman JA, Mino-Kenudson M, Pao W, Iafrate AJ (2012) J Clin Oncol 30(8): 863-70
    › Primary publication · 22215748 (PubMed) · PMC3295572 (PubMed Central)
  65. Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma. Wang NJ, Sanborn Z, Arnett KL, Bayston LJ, Liao W, Proby CM, Leigh IM, Collisson EA, Gordon PB, Jakkula L, Pennypacker S, Zou Y, Sharma M, North JP, Vemula SS, Mauro TM, Neuhaus IM, Leboit PE, Hur JS, Park K, Huh N, Kwok PY, Arron ST, Massion PP, Bale AE, Haussler D, Cleaver JE, Gray JW, Spellman PT, South AP, Aster JC, Blacklow SC, Cho RJ (2011) Proc Natl Acad Sci U S A 108(43): 17761-6
    › Primary publication · 22006338 (PubMed) · PMC3203814 (PubMed Central)
  66. Loss of polymeric immunoglobulin receptor expression is associated with lung tumourigenesis. Ocak S, Pedchenko TV, Chen H, Harris FT, Qian J, Polosukhin V, Pilette C, Sibille Y, Gonzalez AL, Massion PP (2012) Eur Respir J 39(5): 1171-80
    › Primary publication · 21965228 (PubMed) · PMC3717253 (PubMed Central)
  67. Expression of focal adhesion kinase in small-cell lung carcinoma. Ocak S, Chen H, Callison C, Gonzalez AL, Massion PP (2012) Cancer 118(5): 1293-301
    › Primary publication · 21800286 (PubMed) · PMC3673887 (PubMed Central)
  68. Thoracic operations for pulmonary nodules are frequently not futile in patients with benign disease. Grogan EL, Weinstein JJ, Deppen SA, Putnam JB, Nesbitt JC, Lambright ES, Walker RC, Dittus RS, Massion PP (2011) J Thorac Oncol 6(10): 1720-5
    › Primary publication · 21760552 (PubMed) · PMC3712870 (PubMed Central)
  69. Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq. Beane J, Vick J, Schembri F, Anderlind C, Gower A, Campbell J, Luo L, Zhang XH, Xiao J, Alekseyev YO, Wang S, Levy S, Massion PP, Lenburg M, Spira A (2011) Cancer Prev Res (Phila) 4(6): 803-17
    › Primary publication · 21636547 (PubMed) · PMC3694393 (PubMed Central)
  70. Oral iloprost improves endobronchial dysplasia in former smokers. Keith RL, Blatchford PJ, Kittelson J, Minna JD, Kelly K, Massion PP, Franklin WA, Mao J, Wilson DO, Merrick DT, Hirsch FR, Kennedy TC, Bunn PA, Geraci MW, Miller YE (2011) Cancer Prev Res (Phila) 4(6): 793-802
    › Primary publication · 21636546 (PubMed) · PMC3251330 (PubMed Central)
  71. Preferential localization of human origins of DNA replication at the 5'-ends of expressed genes and at evolutionarily conserved DNA sequences. Valenzuela MS, Chen Y, Davis S, Yang F, Walker RL, Bilke S, Lueders J, Martin MM, Aladjem MI, Massion PP, Meltzer PS (2011) PLoS One 6(5): e17308
    › Primary publication · 21602917 (PubMed) · PMC3094316 (PubMed Central)
  72. Accuracy of FDG-PET to diagnose lung cancer in a region of endemic granulomatous disease. Deppen S, Putnam JB, Andrade G, Speroff T, Nesbitt JC, Lambright ES, Massion PP, Walker R, Grogan EL (2011) Ann Thorac Surg 92(2): 428-32; discussion 433
    › Primary publication · 21592456 (PubMed) · PMC3186439 (PubMed Central)
  73. Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium. Polosukhin VV, Cates JM, Lawson WE, Milstone AP, Matafonov AG, Massion PP, Lee JW, Randell SH, Blackwell TS (2011) J Pathol 224(2): 203-11
    › Primary publication · 21557221 (PubMed) · PMC5901746 (PubMed Central)
  74. Advances in proteomic strategies toward the early detection of lung cancer. Hassanein M, Rahman JS, Chaurand P, Massion PP (2011) Proc Am Thorac Soc 8(2): 183-8
    › Primary publication · 21543799 (PubMed) · PMC3131837 (PubMed Central)
  75. Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease. Polosukhin VV, Cates JM, Lawson WE, Zaynagetdinov R, Milstone AP, Massion PP, Ocak S, Ware LB, Lee JW, Bowler RP, Kononov AV, Randell SH, Blackwell TS (2011) Am J Respir Crit Care Med 184(3): 317-27
    › Primary publication · 21512171 (PubMed) · PMC3265275 (PubMed Central)
  76. Role of STRAP in regulating GSK3β function and Notch3 stabilization. Kashikar ND, Zhang W, Massion PP, Gonzalez AL, Datta PK (2011) Cell Cycle 10(10): 1639-54
    › Primary publication · 21502811 (PubMed) · PMC3127163 (PubMed Central)
  77. Evolving concepts in lung carcinogenesis. Gomperts BN, Spira A, Massion PP, Walser TC, Wistuba II, Minna JD, Dubinett SM (2011) Semin Respir Crit Care Med 32(1): 32-43
    › Primary publication · 21500122 (PubMed) · PMC3423907 (PubMed Central)
  78. Lung cancer diagnosis from proteomic analysis of preinvasive lesions. Rahman SM, Gonzalez AL, Li M, Seeley EH, Zimmerman LJ, Zhang XJ, Manier ML, Olson SJ, Shah RN, Miller AN, Putnam JB, Miller YE, Franklin WA, Blot WJ, Carbone DP, Shyr Y, Caprioli RM, Massion PP (2011) Cancer Res 71(8): 3009-17
    › Primary publication · 21487035 (PubMed) · PMC3110721 (PubMed Central)
  79. Methods for peptide and protein quantitation by liquid chromatography-multiple reaction monitoring mass spectrometry. Zhang H, Liu Q, Zimmerman LJ, Ham AJ, Slebos RJ, Rahman J, Kikuchi T, Massion PP, Carbone DP, Billheimer D, Liebler DC (2011) Mol Cell Proteomics 10(6): M110.006593
    › Primary publication · 21357624 (PubMed) · PMC3108838 (PubMed Central)
  80. A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer. Su Z, Dias-Santagata D, Duke M, Hutchinson K, Lin YL, Borger DR, Chung CH, Massion PP, Vnencak-Jones CL, Iafrate AJ, Pao W (2011) J Mol Diagn 13(1): 74-84
    › Primary publication · 21227397 (PubMed) · PMC3070558 (PubMed Central)
  81. Existing general population models inaccurately predict lung cancer risk in patients referred for surgical evaluation. Isbell JM, Deppen S, Putnam JB, Nesbitt JC, Lambright ES, Dawes A, Massion PP, Speroff T, Jones DR, Grogan EL (2011) Ann Thorac Surg 91(1): 227-33; discussion 233
    › Primary publication · 21172518 (PubMed) · PMC3748597 (PubMed Central)
  82. MALDI-MS derived prognostic protein markers for resected non-small cell lung cancer. Xu BJ, Gonzalez AL, Kikuchi T, Yanagisawa K, Massion PP, Wu H, Mason SE, Olson SJ, Shyr Y, Carbone DP, Caprioli RM (2008) Proteomics Clin Appl 2(10-11): 1508-17
    › Primary publication · 21136798 (PubMed) · PMC3728564 (PubMed Central)
  83. National Lung Cancer Screening Trial American College of Radiology Imaging Network Specimen Biorepository originating from the Contemporary Screening for the Detection of Lung Cancer Trial (NLST, ACRIN 6654): design, intent, and availability of specimens for validation of lung cancer biomarkers. Patz EF, Caporaso NE, Dubinett SM, Massion PP, Hirsch FR, Minna JD, Gatsonis C, Duan F, Adams A, Apgar C, Medina RM, Aberle DR (2010) J Thorac Oncol 5(10): 1502-6
    › Primary publication · 20871260 (PubMed) · PMC2963472 (PubMed Central)
  84. DNA copy number aberrations in small-cell lung cancer reveal activation of the focal adhesion pathway. Ocak S, Yamashita H, Udyavar AR, Miller AN, Gonzalez AL, Zou Y, Jiang A, Yi Y, Shyr Y, Estrada L, Quaranta V, Massion PP (2010) Oncogene 29(48): 6331-42
    › Primary publication · 20802517 (PubMed) · PMC4637980 (PubMed Central)
  85. Diagnostic characteristics of a serum biomarker in patients with positron emission tomography scans. Grogan EL, Deppen S, Pecot CV, Putnam JB, Nesbitt JC, Shyr Y, Rajanbabu R, Ory B, Lambright ES, Massion PP (2010) Ann Thorac Surg 89(6): 1724-8; discussion 1728-9
    › Primary publication · 20494018 (PubMed) · PMC3026702 (PubMed Central)
  86. Airway PI3K pathway activation is an early and reversible event in lung cancer development. Gustafson AM, Soldi R, Anderlind C, Scholand MB, Qian J, Zhang X, Cooper K, Walker D, McWilliams A, Liu G, Szabo E, Brody J, Massion PP, Lenburg ME, Lam S, Bild AH, Spira A (2010) Sci Transl Med 2(26): 26ra25
    › Primary publication · 20375364 (PubMed) · PMC3694402 (PubMed Central)
  87. What makes tight glycemic control tight? The impact of variability and nutrition in two clinical studies. Suhaimi F, Le Compte A, Preiser JC, Shaw GM, Massion P, Radermecker R, Pretty CG, Lin J, Desaive T, Chase JG (2010) J Diabetes Sci Technol 4(2): 284-98
    › Primary publication · 20307388 (PubMed) · PMC2864163 (PubMed Central)
  88. High-throughput molecular analysis in lung cancer: insights into biology and potential clinical applications. Ocak S, Sos ML, Thomas RK, Massion PP (2009) Eur Respir J 34(2): 489-506
    › Primary publication · 19648524 (PubMed) · PMC4648268 (PubMed Central)
  89. Recurrent genomic gains in preinvasive lesions as a biomarker of risk for lung cancer. Massion PP, Zou Y, Uner H, Kiatsimkul P, Wolf HJ, Baron AE, Byers T, Jonsson S, Lam S, Hirsch FR, Miller YE, Franklin WA, Varella-Garcia M (2009) PLoS One 4(6): e5611
    › Primary publication · 19547694 (PubMed) · PMC2699220 (PubMed Central)
  90. A novel information retrieval model for high-throughput molecular medicine modalities. Wehbe FH, Brown SH, Massion PP, Gadd CS, Masys DR, Aliferis CF (2009) Cancer Inform : 1-17
    › Primary publication · 19458790 (PubMed) · PMC2664697 (PubMed Central)
  91. Classification by mass spectrometry can accurately and reliably predict outcome in patients with non-small cell lung cancer treated with erlotinib-containing regimen. Salmon S, Chen H, Chen S, Herbst R, Tsao A, Tran H, Sandler A, Billheimer D, Shyr Y, Lee JW, Massion P, Brahmer J, Schiller J, Carbone D, Dang TP (2009) J Thorac Oncol 4(6): 689-96
    › Primary publication · 19404214 (PubMed) · PMC3563261 (PubMed Central)
  92. Mass spectrometry-based proteomic profiling of lung cancer. Ocak S, Chaurand P, Massion PP (2009) Proc Am Thorac Soc 6(2): 159-70
    › Primary publication · 19349484 (PubMed) · PMC2674226 (PubMed Central)
  93. Synergy between phosphatidylinositol 3-kinase/Akt pathway and Bcl-xL in the control of apoptosis in adenocarcinoma cells of the lung. Qian J, Zou Y, Rahman JS, Lu B, Massion PP (2009) Mol Cancer Ther 8(1): 101-9
    › Primary publication · 19139118 (PubMed) · PMC3110728 (PubMed Central)
  94. IkappaB kinase-alpha regulates endothelial cell motility and tumor angiogenesis. DeBusk LM, Massion PP, Lin PC (2008) Cancer Res 68(24): 10223-8
    › Primary publication · 19074890 (PubMed)
  95. Smoking-related genomic signatures in non-small cell lung cancer. Massion PP, Zou Y, Chen H, Jiang A, Coulson P, Amos CI, Wu X, Wistuba I, Wei Q, Shyr Y, Spitz MR (2008) Am J Respir Crit Care Med 178(11): 1164-72
    › Primary publication · 18776155 (PubMed) · PMC2720147 (PubMed Central)
  96. High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry. Groseclose MR, Massion PP, Chaurand P, Caprioli RM (2008) Proteomics 8(18): 3715-24
    › Primary publication · 18712763 (PubMed) · PMC2927989 (PubMed Central)
  97. A high-throughput and sensitive method to measure global DNA methylation: application in lung cancer. Anisowicz A, Huang H, Braunschweiger KI, Liu Z, Giese H, Wang H, Mamaev S, Olejnik J, Massion PP, Del Mastro RG (2008) BMC Cancer : 222
    › Primary publication · 18673580 (PubMed) · PMC2546425 (PubMed Central)
  98. Peroxisome proliferator-activated receptor beta/delta expression and activation in lung cancer. Pedchenko TV, Gonzalez AL, Wang D, DuBois RN, Massion PP (2008) Am J Respir Cell Mol Biol 39(6): 689-96
    › Primary publication · 18566335 (PubMed) · PMC3159083 (PubMed Central)
  99. Role of chromosome 3q amplification in lung cancer. Qian J, Massion PP (2008) J Thorac Oncol 3(3): 212-5
    › Primary publication · 18317062 (PubMed)
  100. Diagnostic accuracy of MALDI mass spectrometric analysis of unfractionated serum in lung cancer. Yildiz PB, Shyr Y, Rahman JS, Wardwell NR, Zimmerman LJ, Shakhtour B, Gray WH, Chen S, Li M, Roder H, Liebler DC, Bigbee WL, Siegfried JM, Weissfeld JL, Gonzalez AL, Ninan M, Johnson DH, Carbone DP, Caprioli RM, Massion PP (2007) J Thorac Oncol 2(10): 893-901
    › Primary publication · 17909350 (PubMed) · PMC4220686 (PubMed Central)
  101. Cytoplasmic clusterin expression is associated with longer survival in patients with resected non small cell lung cancer. Albert JM, Gonzalez A, Massion PP, Chen H, Olson SJ, Shyr Y, Diaz R, Lambright ES, Sandler A, Carbone DP, Putnam JB, Johnson DH, Lu B (2007) Cancer Epidemiol Biomarkers Prev 16(9): 1845-51
    › Primary publication · 17855704 (PubMed)
  102. Association of progressive structural changes in the bronchial epithelium with subepithelial fibrous remodeling: a potential role for hypoxia. Polosukhin VV, Lawson WE, Milstone AP, Egunova SM, Kulipanov AG, Tchuvakin SG, Massion PP, Blackwell TS (2007) Virchows Arch 451(4): 793-803
    › Primary publication · 17674038 (PubMed)
  103. Workshop on imaging science development for cancer prevention and preemption. Kelloff GJ, Sullivan DC, Baker H, Clarke LP, Nordstrom R, Tatum JL, Dorfman GS, Jacobs P, Berg CD, Pomper MG, Birrer MJ, Tempero M, Higley HR, Petty BG, Sigman CC, Maley C, Sharma P, Wax A, Ginsberg GG, Dannenberg AJ, Hawk ET, Messing EM, Grossman HB, Harisinghani M, Bigio IJ, Griebel D, Henson DE, Fabian CJ, Ferrara K, Fantini S, Schnall MD, Zujewski JA, Hayes W, Klein EA, DeMarzo A, Ocak I, Ketterling JA, Tempany C, Shtern F, Parnes HL, Gomez J, Srivastava S, Szabo E, Lam S, Seibel EJ, Massion P, McLennan G, Cleary K, Suh R, Burt RW, Pfeiffer RM, Hoffman JM, Roy HK, Wang T, Limburg PJ, El-Deiry WS, Papadimitrakopoulou V, Hittelman WN, MacAulay C, Veltri RW, Solomon D, Jeronimo J, Richards-Kortum R, Johnson KA, Viner JL, Stratton SP, Rajadhyaksha M, Dhawan A, Workshop Program Committee (2007) Cancer Biomark 3(1): 1-33
    › Primary publication · 17655039 (PubMed)
  104. Mass spectrometry to classify non-small-cell lung cancer patients for clinical outcome after treatment with epidermal growth factor receptor tyrosine kinase inhibitors: a multicohort cross-institutional study. Taguchi F, Solomon B, Gregorc V, Roder H, Gray R, Kasahara K, Nishio M, Brahmer J, Spreafico A, Ludovini V, Massion PP, Dziadziuszko R, Schiller J, Grigorieva J, Tsypin M, Hunsucker SW, Caprioli R, Duncan MW, Hirsch FR, Bunn PA, Carbone DP (2007) J Natl Cancer Inst 99(11): 838-46
    › Primary publication · 17551144 (PubMed)
  105. Proteomic strategies for the characterization and the early detection of lung cancer. Massion PP, Caprioli RM (2006) J Thorac Oncol 1(9): 1027-39
    › Primary publication · 17409991 (PubMed)
  106. Relevance of nitric oxide for myocardial remodeling. Massion PB, Balligand JL (2007) Curr Heart Fail Rep 4(1): 18-25
    › Primary publication · 17386181 (PubMed)
  107. PDGFR-beta expression in small cell lung cancer patients. Shinohara ET, Gonzalez A, Massion PP, Olson SJ, Albert JM, Shyr Y, Carbone DP, Johnson DH, Hallahan DE, Lu B (2007) Int J Radiat Oncol Biol Phys 67(2): 431-7
    › Primary publication · 17236966 (PubMed)
  108. PIK3CA gene mutations in pediatric and adult glioblastoma multiforme. Gallia GL, Rand V, Siu IM, Eberhart CG, James CD, Marie SK, Oba-Shinjo SM, Carlotti CG, Caballero OL, Simpson AJ, Brock MV, Massion PP, Carson BS, Riggins GJ (2006) Mol Cancer Res 4(10): 709-14
    › Primary publication · 17050665 (PubMed)
  109. Selective profiling of proteins in lung cancer cells from fine-needle aspirates by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Amann JM, Chaurand P, Gonzalez A, Mobley JA, Massion PP, Carbone DP, Caprioli RM (2006) Clin Cancer Res 12(17): 5142-50
    › Primary publication · 16951232 (PubMed)
  110. Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas. Stacy DR, Ely K, Massion PP, Yarbrough WG, Hallahan DE, Sekhar KR, Freeman ML (2006) Head Neck 28(9): 813-8
    › Primary publication · 16637057 (PubMed)
  111. Restoration of TGF-beta signalling reduces tumorigenicity in human lung cancer cells. Anumanthan G, Halder SK, Osada H, Takahashi T, Massion PP, Carbone DP, Datta PK (2005) Br J Cancer 93(10): 1157-67
    › Primary publication · 16251876 (PubMed) · PMC2361493 (PubMed Central)
  112. Proteomic patterns of preinvasive bronchial lesions. Rahman SM, Shyr Y, Yildiz PB, Gonzalez AL, Li H, Zhang X, Chaurand P, Yanagisawa K, Slovis BS, Miller RF, Ninan M, Miller YE, Franklin WA, Caprioli RM, Carbone DP, Massion PP (2005) Am J Respir Crit Care Med 172(12): 1556-62
    › Primary publication · 16179643 (PubMed) · PMC2718455 (PubMed Central)
  113. Cloned fusion product from a rare t(15;19)(q13.2;p13.1) inhibit S phase in vitro. Haruki N, Kawaguchi KS, Eichenberger S, Massion PP, Gonzalez A, Gazdar AF, Minna JD, Carbone DP, Dang TP (2005) J Med Genet 42(7): 558-64
    › Primary publication · 15994877 (PubMed) · PMC1736105 (PubMed Central)
  114. Novel strategies for the early detection and prevention of lung cancer. Wardwell NR, Massion PP (2005) Semin Oncol 32(3): 259-68
    › Primary publication · 15988680 (PubMed)
  115. Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers. Haruki N, Kawaguchi KS, Eichenberger S, Massion PP, Olson S, Gonzalez A, Carbone DP, Dang TP (2005) Cancer Res 65(9): 3555-61
    › Primary publication · 15867348 (PubMed)
  116. Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma. Shinohara ET, Gonzalez A, Massion PP, Chen H, Li M, Freyer AS, Olson SJ, Andersen JJ, Shyr Y, Carbone DP, Johnson DH, Hallahan DE, Lu B (2005) Cancer 103(8): 1685-92
    › Primary publication · 15742356 (PubMed)
  117. Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer. Amann J, Kalyankrishna S, Massion PP, Ohm JE, Girard L, Shigematsu H, Peyton M, Juroske D, Huang Y, Stuart Salmon J, Kim YH, Pollack JR, Yanagisawa K, Gazdar A, Minna JD, Kurie JM, Carbone DP (2005) Cancer Res 65(1): 226-35
    › Primary publication · 15665299 (PubMed)
  118. Cardiomyocyte-restricted overexpression of endothelial nitric oxide synthase (NOS3) attenuates beta-adrenergic stimulation and reinforces vagal inhibition of cardiac contraction. Massion PB, Dessy C, Desjardins F, Pelat M, Havaux X, Belge C, Moulin P, Guiot Y, Feron O, Janssens S, Balligand JL (2004) Circulation 110(17): 2666-72
    › Primary publication · 15492314 (PubMed)
  119. Early involvement of the phosphatidylinositol 3-kinase/Akt pathway in lung cancer progression. Massion PP, Taflan PM, Shyr Y, Rahman SM, Yildiz P, Shakthour B, Edgerton ME, Ninan M, Andersen JJ, Gonzalez AL (2004) Am J Respir Crit Care Med 170(10): 1088-94
    › Primary publication · 15317667 (PubMed)
  120. Nuclear survivin as a biomarker for non-small-cell lung cancer. Lu B, Gonzalez A, Massion PP, Shyr Y, Shaktour B, Carbone DP, Hallahan DE (2004) Br J Cancer 91(3): 537-40
    › Primary publication · 15266313 (PubMed) · PMC2409840 (PubMed Central)
  121. 15-Lipoxygenase-2 expression in benign and neoplastic lung: an immunohistochemical study and correlation with tumor grade and proliferation. Gonzalez AL, Roberts RL, Massion PP, Olson SJ, Shyr Y, Shappell SB (2004) Hum Pathol 35(7): 840-9
    › Primary publication · 15257547 (PubMed)
  122. Role of p63 amplification and overexpression in lung cancer development. Massion PP, Taflan PM, Rahman SM, Yildiz P, Shyr Y, Carbone DP, Gonzalez AL (2004) Chest 125(5 Suppl): 102S
    › Primary publication · 15136437 (PubMed)
  123. The molecular basis of lung cancer: molecular abnormalities and therapeutic implications. Massion PP, Carbone DP (2003) Respir Res : 12
    › Primary publication · 14641911 (PubMed) · PMC314397 (PubMed Central)
  124. Significance of p63 amplification and overexpression in lung cancer development and prognosis. Massion PP, Taflan PM, Jamshedur Rahman SM, Yildiz P, Shyr Y, Edgerton ME, Westfall MD, Roberts JR, Pietenpol JA, Carbone DP, Gonzalez AL (2003) Cancer Res 63(21): 7113-21
    › Primary publication · 14612504 (PubMed)
  125. Proteomic patterns of tumour subsets in non-small-cell lung cancer. Yanagisawa K, Shyr Y, Xu BJ, Massion PP, Larsen PH, White BC, Roberts JR, Edgerton M, Gonzalez A, Nadaf S, Moore JH, Caprioli RM, Carbone DP (2003) Lancet 362(9382): 433-9
    › Primary publication · 12927430 (PubMed)
  126. From clinical and pathologic to molecular staging of lung cancer. Massion PP, Carbone DP (2003) Am J Respir Crit Care Med 167(12): 1587-8
    › Primary publication · 12796051 (PubMed)
  127. Machine learning models for lung cancer classification using array comparative genomic hybridization. Aliferis CF, Hardin D, Massion PP (2002) Proc AMIA Symp : 7-11
    › Primary publication · 12463776 (PubMed) · PMC2244172 (PubMed Central)
  128. Genomic copy number analysis of non-small cell lung cancer using array comparative genomic hybridization: implications of the phosphatidylinositol 3-kinase pathway. Massion PP, Kuo WL, Stokoe D, Olshen AB, Treseler PA, Chin K, Chen C, Polikoff D, Jain AN, Pinkel D, Albertson DG, Jablons DM, Gray JW (2002) Cancer Res 62(13): 3636-40
    › Primary publication · 12097266 (PubMed)
  129. Secretory component production by human bronchial epithelial cells is upregulated by interferon gamma. Godding V, Sibille Y, Massion PP, Delos M, Sibille C, Thurion P, Giffroy D, Langendries A, Vaerman JP (1998) Eur Respir J 11(5): 1043-52
    › Primary publication · 9648953 (PubMed)
  130. Dimethyl sulfoxide decreases interleukin-8-mediated neutrophil recruitment in the airways. Massion PP, Lindén A, Inoue H, Mathy M, Grattan KM, Nadel JA (1996) Am J Physiol 271(5 Pt 1): L838-43
    › Primary publication · 8944728 (PubMed)
  131. Ragweed antigen causes interleukin-8 production in sensitized dog trachea. Kaneko T, Massion PR, Hara M, Nadel JA (1996) Am J Respir Crit Care Med 153(1): 136-40
    › Primary publication · 8542106 (PubMed)
  132. Parainfluenza (Sendai) virus infects ciliated cells and secretory cells but not basal cells of rat tracheal epithelium. Massion PP, Funari CC, Ueki I, Ikeda S, McDonald DM, Nadel JA (1993) Am J Respir Cell Mol Biol 9(4): 361-70
    › Primary publication · 8398175 (PubMed)
  133. Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro. Massion PP, Inoue H, Richman-Eisenstat J, Grunberger D, Jorens PG, Housset B, Pittet JF, Wiener-Kronish JP, Nadel JA (1994) J Clin Invest 93(1): 26-32
    › Primary publication · 8282796 (PubMed) · PMC293717 (PubMed Central)
  134. Pseudomonas stimulates interleukin-8 mRNA expression selectively in airway epithelium, in gland ducts, and in recruited neutrophils. Inoue H, Massion PP, Ueki IF, Grattan KM, Hara M, Dohrman AF, Chan B, Lausier JA, Golden JA, Nadel JA (1994) Am J Respir Cell Mol Biol 11(6): 651-63
    › Primary publication · 7946394 (PubMed)
  135. Pseudomonas-induced neutrophil recruitment in the dog airway in vivo is mediated in part by IL-8 and inhibited by a leumedin. Jorens PG, Richman-Eisenstat JB, Housset BP, Massion PP, Ueki I, Nadel JA (1994) Eur Respir J 7(11): 1925-31
    › Primary publication · 7875261 (PubMed)
  136. Staphylococcus aureus stimulates neutrophil recruitment by stimulating interleukin-8 production in dog trachea. Massion PP, Hébert CA, Leong S, Chan B, Inoue H, Grattan K, Sheppard D, Nadel JA (1995) Am J Physiol 268(1 Pt 1): L85-94
    › Primary publication · 7840233 (PubMed)
  137. Plasma extravasation in the rat trachea induced by cold air is mediated by tachykinin release from sensory nerves. Yoshihara S, Chan B, Yamawaki I, Geppetti P, Ricciardolo FL, Massion PP, Nadel JA (1995) Am J Respir Crit Care Med 151(4): 1011-7
    › Primary publication · 7697224 (PubMed)
  138. Viral infection potentiates the increase in airway blood flow produced by substance P. Yamawaki I, Geppetti P, Bertrand C, Chan B, Massion P, Piedimonte G, Nadel JA (1995) J Appl Physiol (1985) 79(2): 398-404
    › Primary publication · 7592194 (PubMed)
  139. Role of recruited neutrophils in interleukin-8 production in dog trachea after stimulation with Pseudomonas in vivo. Inoue H, Hara M, Massion PP, Grattan KM, Lausier JA, Chan B, Kaneko T, Isono K, Jorens PG, Ueki IF (1995) Am J Respir Cell Mol Biol 13(5): 570-7
    › Primary publication · 7576693 (PubMed)

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Acetyl Coenzyme A Alternative Splicing Amino Acid Sequence Antigens, CD Artificial Intelligence Biopsy, Needle Carbonic Anhydrase IX Carbonic Anhydrases CD4-Positive T-Lymphocytes Cell Death Cell Polarity Chi-Square Distribution Cohort Studies Coronary Artery Bypass Cyclin D1 Gene Dosage Medical Records Models, Biological Molecular Sequence Data Morpholines Neovascularization, Pathologic Peptide Fragments Pericytes Positron-Emission Tomography Prospective Studies Protein Isoforms Proteome Pyrazoles Rats, Inbred F344 RNA-Binding Proteins