Stephen Bruehl
Faculty Member
Last active: 2/12/2015


Dr. Bruehl's general research focus is chronic pain. This work is specifically focused on the role of endogenous opioid system dysfunction in chronic pain states, and alterations in the relationship between cardiovascular and pain regulatory systems in chronic pain conditions. Dr. Bruehl's work also addresses the diagnosis and management of complex regional pain syndrome. Another area of Dr. Bruehl's research is the relationship between psychological factors (e.g., anger) and endogenous opioid system functioning as it impacts on pain and cardiovascular stress reactivity.


The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Chronic pain, body mass index and cardiovascular disease risk factors: tests of moderation, unique and shared relationships in the Study of Women's Health Across the Nation (SWAN). Burns JW, Quartana PJ, Bruehl S, Janssen I, Dugan SA, Appelhans B, Matthews KA, Kravitz HM (2015) J Behav Med 38(2): 372-83
    › Primary publication · 25427423 (PubMed) · PMC4496954 (PubMed Central)
  2. Use of a medication quantification scale for comparison of pain medication usage in patients with complex regional pain syndrome (CRPS). Gallizzi MA, Khazai RS, Gagnon CM, Bruehl S, Harden RN (2015) Pain Med 16(3): 494-500
    › Primary publication · 25220567 (PubMed)
  3. Anger arousal and behavioral anger regulation in everyday life among patients with chronic low back pain: Relationships to patient pain and function. Burns JW, Gerhart JI, Bruehl S, Peterson KM, Smith DA, Porter LS, Schuster E, Kinner E, Buvanendran A, Fras AM, Keefe FJ (2015) Health Psychol 34(5): 547-55
    › Primary publication · 25110843 (PubMed) · PMC4513650 (PubMed Central)
  4. Chronic pain and cardiovascular stress responses in a general population: the Tromsø Study. Olsen RB, Bruehl S, Nielsen CS, Rosseland LA, Eggen AE, Stubhaug A (2014) J Behav Med 37(6): 1193-201
    › Primary publication · 24793322 (PubMed)
  5. Relationship between endogenous opioid function and opioid analgesic adverse effects. Gupta RK, Bruehl S, Burns JW, Buvanendran A, Chont M, Schuster E, France CR (2014) Reg Anesth Pain Med 39(3): 219-24
    › Primary publication · 24682081 (PubMed) · PMC4003486 (PubMed Central)
  6. The ACTTION-American Pain Society Pain Taxonomy (AAPT): an evidence-based and multidimensional approach to classifying chronic pain conditions. Fillingim RB, Bruehl S, Dworkin RH, Dworkin SF, Loeser JD, Turk DC, Widerstrom-Noga E, Arnold L, Bennett R, Edwards RR, Freeman R, Gewandter J, Hertz S, Hochberg M, Krane E, Mantyh PW, Markman J, Neogi T, Ohrbach R, Paice JA, Porreca F, Rappaport BA, Smith SM, Smith TJ, Sullivan MD, Verne GN, Wasan AD, Wesselmann U (2014) J Pain 15(3): 241-9
    › Primary publication · 24581634 (PubMed) · PMC4454364 (PubMed Central)
  7. Endogenous opioid inhibition of chronic low-back pain influences degree of back pain relief after morphine administration. Bruehl S, Burns JW, Gupta R, Buvanendran A, Chont M, Schuster E, France CR (2014) Reg Anesth Pain Med 39(2): 120-5
    › Primary publication · 24553304 (PubMed) · PMC3933525 (PubMed Central)
  8. Children and adolescents with complex regional pain syndrome: more psychologically distressed than other children in pain? Logan DE, Williams SE, Carullo VP, Claar RL, Bruehl S, Berde CB (2013) Pain Res Manag 18(2): 87-93
    › Primary publication · 23662291 (PubMed) · PMC3718058 (PubMed Central)
  9. Anger regulation style, anger arousal and acute pain sensitivity: evidence for an endogenous opioid "triggering" model. Burns JW, Bruehl S, Chont M (2014) J Behav Med 37(4): 642-53
    › Primary publication · 23624641 (PubMed) · PMC4180113 (PubMed Central)
  10. The osteoarthritis knee model: psychophysical characteristics and putative outcomes. Harden RN, Wallach G, Gagnon CM, Zereshki A, Mukai A, Saracoglu M, Kuroda MM, Graciosa JR, Bruehl S (2013) J Pain 14(3): 281-9
    › Primary publication · 23380268 (PubMed)
  11. Complex regional pain syndrome: practical diagnostic and treatment guidelines, 4th edition. Harden RN, Oaklander AL, Burton AW, Perez RS, Richardson K, Swan M, Barthel J, Costa B, Graciosa JR, Bruehl S, Reflex Sympathetic Dystrophy Syndrome Association (2013) Pain Med 14(2): 180-229
    › Primary publication · 23331950 (PubMed)
  12. Hypertension prevalence and diminished blood pressure-related hypoalgesia in individuals reporting chronic pain in a general population: the Tromsø study. Olsen RB, Bruehl S, Nielsen CS, Rosseland LA, Eggen AE, Stubhaug A (2013) Pain 154(2): 257-262
    › Primary publication · 23245863 (PubMed)