Deepak Gupta
Last active: 11/14/2014


I am an Instructor in Medicine and physician scientist in the Vanderbilt Heart and Vascular Institute and Cardiovascular Translational Research Center.  My patient oriented clinical research predominantly focuses on the development and outcomes in 1) heart failure and 2) atrial fibrillation.

My clinical interests include the care of patients with heart failure with preserved ejection fraction, as well as non-invasive cardiac imaging, including echocardiography, cardiac magnetic resonance, and nuclear imaging.

I came to Vanderbilt University Medical Center in 2013 from Brigham and Women's Hospital and Harvard Medical School where I completed advanced training in non-invasive cardiac imaging and research.  Prior to this, I was a cardiovascular medicine fellow at Northwestern University and resident in internal medicine at Duke University.  I obtained my medical degree from The Ohio State University College of Medicine.



The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Sex-specific cardiovascular structure and function in heart failure with preserved ejection fraction. Gori M, Lam CS, Gupta DK, Santos AB, Cheng S, Shah AM, Claggett B, Zile MR, Kraigher-Krainer E, Pieske B, Voors AA, Packer M, Bransford T, Lefkowitz M, McMurray JJ, Solomon SD, PARAMOUNT Investigators (2014) Eur J Heart Fail 16(5): 535-42
    › Primary publication · 24574260 (PubMed)
  2. Insulin resistance and incident heart failure the ARIC study (Atherosclerosis Risk in Communities). Vardeny O, Gupta DK, Claggett B, Burke S, Shah A, Loehr L, Rasmussen-Torvik L, Selvin E, Chang PP, Aguilar D, Solomon SD (2013) JACC Heart Fail 1(6): 531-6
    › Primary publication · 24455475 (PubMed) · PMC3893700 (PubMed Central)
  3. Prognostic importance of pathophysiologic markers in patients with heart failure and preserved ejection fraction. Burke MA, Katz DH, Beussink L, Selvaraj S, Gupta DK, Fox J, Chakrabarti S, Sauer AJ, Rich JD, Freed BH, Shah SJ (2014) Circ Heart Fail 7(2): 288-99
    › Primary publication · 24365774 (PubMed) · PMC5947992 (PubMed Central)
  4. Left atrial structure and function in atrial fibrillation: ENGAGE AF-TIMI 48. Gupta DK, Shah AM, Giugliano RP, Ruff CT, Antman EM, Grip LT, Deenadayalu N, Hoffman E, Patel I, Shi M, Mercuri M, Mitrovic V, Braunwald E, Solomon SD, Effective aNticoaGulation with factor xA next GEneration in AF-Thrombolysis In Myocardial Infarction 48 Echocardiographic Study Investigators (2014) Eur Heart J 35(22): 1457-65
    › Primary publication · 24302269 (PubMed) · PMC4048534 (PubMed Central)
  5. Ultrastructural and cellular basis for the development of abnormal myocardial mechanics during the transition from hypertension to heart failure. Shah SJ, Aistrup GL, Gupta DK, O'Toole MJ, Nahhas AF, Schuster D, Chirayil N, Bassi N, Ramakrishna S, Beussink L, Misener S, Kane B, Wang D, Randolph B, Ito A, Wu M, Akintilo L, Mongkolrattanothai T, Reddy M, Kumar M, Arora R, Ng J, Wasserstrom JA (2014) Am J Physiol Heart Circ Physiol 306(1): H88-100
    › Primary publication · 24186100 (PubMed) · PMC3920157 (PubMed Central)
  6. Impaired systolic function by strain imaging in heart failure with preserved ejection fraction. Kraigher-Krainer E, Shah AM, Gupta DK, Santos A, Claggett B, Pieske B, Zile MR, Voors AA, Lefkowitz MP, Packer M, McMurray JJ, Solomon SD, PARAMOUNT Investigators (2014) J Am Coll Cardiol 63(5): 447-56
    › Primary publication · 24184245 (PubMed) · PMC7195816 (PubMed Central)
  7. Differential influence of distinct components of increased blood pressure on cardiovascular outcomes: from the atherosclerosis risk in communities study. Cheng S, Gupta DK, Claggett B, Sharrett AR, Shah AM, Skali H, Takeuchi M, Ni H, Solomon SD (2013) Hypertension 62(3): 492-8
    › Primary publication · 23876475 (PubMed) · PMC3828292 (PubMed Central)
  8. Inhibition of the late sodium current slows t-tubule disruption during the progression of hypertensive heart disease in the rat. Aistrup GL, Gupta DK, Kelly JE, O'Toole MJ, Nahhas A, Chirayil N, Misener S, Beussink L, Singh N, Ng J, Reddy M, Mongkolrattanothai T, El-Bizri N, Rajamani S, Shryock JC, Belardinelli L, Shah SJ, Wasserstrom JA (2013) Am J Physiol Heart Circ Physiol 305(7): H1068-79
    › Primary publication · 23873796 (PubMed) · PMC5504390 (PubMed Central)
  9. Heart failure with preserved ejection fraction in African Americans: The ARIC (Atherosclerosis Risk In Communities) study. Gupta DK, Shah AM, Castagno D, Takeuchi M, Loehr LR, Fox ER, Butler KR, Mosley TH, Kitzman DW, Solomon SD (2013) JACC Heart Fail 1(2): 156-63
    › Primary publication · 23671819 (PubMed) · PMC3650857 (PubMed Central)
  10. Cardiovascular imaging in clinical practice: what does late gadolinium enhance? Gupta DK, Kwong RY, Pfeffer MA (2013) JAMA 309(9): 929-30
    › Primary publication · 23462791 (PubMed) · PMC4382352 (PubMed Central)
  11. Safety and feasibility of adjunctive regadenoson injection at peak exercise during exercise myocardial perfusion imaging: The Both Exercise and Regadenoson Stress Test (BERST) trial. Ross MI, Wu E, Wilkins JT, Gupta D, Shen S, Aulwes D, Montero K, Holly TA (2013) J Nucl Cardiol 20(2): 197-204
    › Primary publication · 23404232 (PubMed)
  12. In response to "a prospective, randomized trial of an emergency department observation unit for acute onset atrial fibrillation". Goyal N, Gupta DK (2009) Ann Emerg Med 53(5): 695-6; author reply 696-7
    › Primary publication · 19380051 (PubMed)
  13. Extraocular muscle dystonia due to acquired (non-Wilsonian) hepatocerebral degeneration. Ferrara J, Gupta D, Foster E, Garman K, Stacy M (2008) Mov Disord 23(6): 875-8
    › Primary publication · 18361477 (PubMed)
  14. TGF-beta1 induction of the adenine nucleotide translocator 1 in astrocytes occurs through Smads and Sp1 transcription factors. Law AK, Gupta D, Levy S, Wallace DC, McKeon RJ, Buck CR (2004) BMC Neurosci : 1
    › Primary publication · 14720305 (PubMed) · PMC324399 (PubMed Central)
  15. TIGR is upregulated in the chronic glial scar in response to central nervous system injury and inhibits neurite outgrowth. Jurynec MJ, Riley CP, Gupta DK, Nguyen TD, McKeon RJ, Buck CR (2003) Mol Cell Neurosci 23(1): 69-80
    › Primary publication · 12799138 (PubMed)
  16. Increased adenine nucleotide translocator 1 in reactive astrocytes facilitates glutamate transport. Buck CR, Jurynec MJ, Gupta DK, Law AK, Bilger J, Wallace DC, McKeon RJ (2003) Exp Neurol 181(2): 149-58
    › Primary publication · 12781988 (PubMed) · PMC2821056 (PubMed Central)