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The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Mycobacterium tuberculosis programs mesenchymal stem cells to establish dormancy and persistence. Fatima S, Kamble SS, Dwivedi VP, Bhattacharya D, Kumar S, Ranganathan A, Van Kaer L, Mohanty S, Das G (2020) J Clin Invest 130(2): 655-661
    › Primary publication · 31647784 (PubMed) · PMC6994115 (PubMed Central)
  2. What one lipid giveth, another taketh away. Joyce S, Spiller BW, Van Kaer L (2019) Nat Immunol 20(12): 1559-1561
    › Primary publication · 31636467 (PubMed) · PMC7755123 (PubMed Central)
  3. Fluctuations of Spleen Cytokine and Blood Lactate, Importance of Cellular Immunity in Host Defense Against Blood Stage Malaria . Imai T, Suzue K, Ngo-Thanh H, Ono S, Orita W, Suzuki H, Shimokawa C, Olia A, Obi S, Taniguchi T, Ishida H, Van Kaer L, Murata S, Tanaka K, Hisaeda H (2019) Front Immunol : 2207
    › Primary publication · 31608052 (PubMed) · PMC6773889 (PubMed Central)
  4. IL-10-producing B cells are enriched in murine pericardial adipose tissues and ameliorate the outcome of acute myocardial infarction. Wu L, Dalal R, Cao CD, Postoak JL, Yang G, Zhang Q, Wang Z, Lal H, Van Kaer L (2019) Proc Natl Acad Sci U S A 116(43): 21673-21684
    › Primary publication · 31591231 (PubMed) · PMC6815157 (PubMed Central)
  5. Curcumin Nanoparticles Enhance Mycobacterium bovis BCG Vaccine Efficacy by Modulating Host Immune Responses. Ahmad S, Bhattacharya D, Kar S, Ranganathan A, Van Kaer L, Das G (2019) Infect Immun 87(11)
    › Primary publication · 31481412 (PubMed) · PMC6803339 (PubMed Central)
  6. Editorial: Role of CD1- and MR1-Restricted T Cells in Immunity and Disease. Iwabuchi K, Van Kaer L (2019) Front Immunol : 1837
    › Primary publication · 31447847 (PubMed) · PMC6691045 (PubMed Central)
  7. Innate, innate-like and adaptive lymphocytes in the pathogenesis of MS and EAE. Van Kaer L, Postoak JL, Wang C, Yang G, Wu L (2019) Cell Mol Immunol 16(6): 531-539
    › Primary publication · 30874627 (PubMed) · PMC6804597 (PubMed Central)
  8. iNKT Cell Activation Exacerbates the Development of Huntington's Disease in R6/2 Transgenic Mice. Park HJ, Lee SW, Im W, Kim M, Van Kaer L, Hong S (2019) Mediators Inflamm : 3540974
    › Primary publication · 30766446 (PubMed) · PMC6350536 (PubMed Central)
  9. The Role of Autophagy in iNKT Cell Development. Yang G, Driver JP, Van Kaer L (2018) Front Immunol : 2653
    › Primary publication · 30487800 (PubMed) · PMC6246678 (PubMed Central)
  10. iNKT Cells Suppress Pathogenic NK1.1CD8 T Cells in DSS-Induced Colitis. Lee SW, Park HJ, Cheon JH, Wu L, Van Kaer L, Hong S (2018) Front Immunol : 2168
    › Primary publication · 30333822 (PubMed) · PMC6176072 (PubMed Central)
  11. PD-1 up-regulation on CD4 T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production. Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, Ayers GD, Bernard GR, Culver DA, Montgomery CG, Maher TM, Molyneaux PL, Noth I, Mutsaers SE, Prele CM, Peebles RS, Newcomb DC, Kaminski N, Blackwell TS, Van Kaer L, Drake WP (2018) Sci Transl Med 10(460)
    › Primary publication · 30257954 (PubMed) · PMC6263177 (PubMed Central)
  12. How Superantigens Bind MHC. Van Kaer L (2018) J Immunol 201(7): 1817-1818
    › Primary publication · 30224360 (PubMed)
  13. Graphene oxide polarizes iNKT cells for production of TGFβ and attenuates inflammation in an iNKT cell-mediated sepsis model. Lee SW, Park HJ, Van Kaer L, Hong S, Hong S (2018) Sci Rep 8(1): 10081
    › Primary publication · 29973666 (PubMed) · PMC6031608 (PubMed Central)
  14. Autophagy-related protein Vps34 controls the homeostasis and function of antigen cross-presenting CD8α dendritic cells. Parekh VV, Pabbisetty SK, Wu L, Sebzda E, Martinez J, Zhang J, Van Kaer L (2017) Proc Natl Acad Sci U S A 114(31): E6371-E6380
    › Primary publication · 28716903 (PubMed) · PMC5547642 (PubMed Central)
  15. Peripheral tolerance can be modified by altering KLF2-regulated Treg migration. Pabbisetty SK, Rabacal W, Volanakis EJ, Parekh VV, Olivares-Villagómez D, Cendron D, Boyd KL, Van Kaer L, Sebzda E (2016) Proc Natl Acad Sci U S A 113(32): E4662-70
    › Primary publication · 27462110 (PubMed) · PMC4987800 (PubMed Central)
  16. Adipocyte-specific CD1d-deficiency mitigates diet-induced obesity and insulin resistance in mice. Satoh M, Hoshino M, Fujita K, Iizuka M, Fujii S, Clingan CS, Van Kaer L, Iwabuchi K (2016) Sci Rep : 28473
    › Primary publication · 27329323 (PubMed) · PMC4916414 (PubMed Central)
  17. Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation. Liu Q, Sanai N, Jin WN, La Cava A, Van Kaer L, Shi FD (2016) Nat Neurosci 19(2): 243-52
    › Primary publication · 26752157 (PubMed) · PMC5336309 (PubMed Central)
  18. Strategies to improve BCG vaccine efficacy. Bali P, Tousif S, Das G, Van Kaer L (2015) Immunotherapy 7(9): 945-8
    › Primary publication · 26310608 (PubMed)
  19. iCD8α cells: living at the edge of the intestinal immune system. Olivares-Villagómez D, Van Kaer L (2015) Oncotarget 6(24): 19964-5
    › Primary publication · 26197090 (PubMed) · PMC4652978 (PubMed Central)
  20. Natural killer T cells in multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis. Van Kaer L, Wu L, Parekh VV (2015) Immunology 146(1): 1-10
    › Primary publication · 26032048 (PubMed) · PMC4552496 (PubMed Central)
  21. The Response of CD1d-Restricted Invariant NKT Cells to Microbial Pathogens and Their Products. Van Kaer L, Parekh VV, Wu L (2015) Front Immunol : 226
    › Primary publication · 26029211 (PubMed) · PMC4429631 (PubMed Central)
  22. Innate and virtual memory T cells in man. Van Kaer L (2015) Eur J Immunol 45(7): 1916-20
    › Primary publication · 26013879 (PubMed) · PMC4540369 (PubMed Central)
  23. Mycobacterium tuberculosis TlyA Protein Negatively Regulates T Helper (Th) 1 and Th17 Differentiation and Promotes Tuberculosis Pathogenesis. Rahman MA, Sobia P, Dwivedi VP, Bhawsar A, Singh DK, Sharma P, Moodley P, Van Kaer L, Bishai WR, Das G (2015) J Biol Chem 290(23): 14407-17
    › Primary publication · 25847237 (PubMed) · PMC4505508 (PubMed Central)
  24. Bee venom stirs up buzz in antigen presentation. Van Kaer L (2015) J Exp Med 212(2): 126
    › Primary publication · 25646264 (PubMed) · PMC4322043 (PubMed Central)
  25. Simultaneous inhibition of T helper 2 and T regulatory cell differentiation by small molecules enhances Bacillus Calmette-Guerin vaccine efficacy against tuberculosis. Bhattacharya D, Dwivedi VP, Kumar S, Reddy MC, Van Kaer L, Moodley P, Das G (2014) J Biol Chem 289(48): 33404-11
    › Primary publication · 25315774 (PubMed) · PMC4246096 (PubMed Central)
  26. Spleen supports a pool of innate-like B cells in white adipose tissue that protects against obesity-associated insulin resistance. Wu L, Parekh VV, Hsiao J, Kitamura D, Van Kaer L (2014) Proc Natl Acad Sci U S A 111(43): E4638-47
    › Primary publication · 25313053 (PubMed) · PMC4217427 (PubMed Central)
  27. CD8αα⁺ innate-type lymphocytes in the intestinal epithelium mediate mucosal immunity. Van Kaer L, Algood HMS, Singh K, Parekh VV, Greer MJ, Piazuelo MB, Weitkamp JH, Matta P, Chaturvedi R, Wilson KT, Olivares-Villagómez D (2014) Immunity 41(3): 451-464
    › Primary publication · 25220211 (PubMed) · PMC4169715 (PubMed Central)
  28. Isoniazid induces apoptosis of activated CD4+ T cells: implications for post-therapy tuberculosis reactivation and reinfection. Tousif S, Singh DK, Ahmad S, Moodley P, Bhattacharyya M, Van Kaer L, Das G (2014) J Biol Chem 289(44): 30190-30195
    › Primary publication · 25202011 (PubMed) · PMC4215201 (PubMed Central)
  29. Endothelial JAM-A promotes reovirus viremia and bloodstream dissemination. Lai CM, Boehme KW, Pruijssers AJ, Parekh VV, Van Kaer L, Parkos CA, Dermody TS (2015) J Infect Dis 211(3): 383-93
    › Primary publication · 25149763 (PubMed) · PMC4351375 (PubMed Central)
  30. Small molecule-directed immunotherapy against recurrent infection by Mycobacterium tuberculosis. Bhattacharya D, Dwivedi VP, Maiga M, Maiga M, Van Kaer L, Bishai WR, Das G (2014) J Biol Chem 289(23): 16508-15
    › Primary publication · 24711459 (PubMed) · PMC4047417 (PubMed Central)
  31. Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression, and protects from colitis. Ahmad R, Chaturvedi R, Olivares-Villagómez D, Habib T, Asim M, Shivesh P, Polk DB, Wilson KT, Washington MK, Van Kaer L, Dhawan P, Singh AB (2014) Mucosal Immunol 7(6): 1340-53
    › Primary publication · 24670427 (PubMed) · PMC4221190 (PubMed Central)
  32. A dihydro-pyrido-indole potently inhibits HSV-1 infection by interfering the viral immediate early transcriptional events. Bag P, Ojha D, Mukherjee H, Halder UC, Mondal S, Biswas A, Sharon A, Van Kaer L, Chakrabarty S, Das G, Mitra D, Chattopadhyay D (2014) Antiviral Res : 126-34
    › Primary publication · 24576908 (PubMed)
  33. Mycobacterium tuberculosis subverts the TLR-2-MyD88 pathway to facilitate its translocation into the cytosol. Rahman A, Sobia P, Gupta N, Kaer LV, Das G (2014) PLoS One 9(1): e86886
    › Primary publication · 24475192 (PubMed) · PMC3903598 (PubMed Central)
  34. Activation of the epidermal growth factor receptor in macrophages regulates cytokine production and experimental colitis. Lu N, Wang L, Cao H, Liu L, Van Kaer L, Washington MK, Rosen MJ, Dubé PE, Wilson KT, Ren X, Hao X, Polk DB, Yan F (2014) J Immunol 192(3): 1013-23
    › Primary publication · 24391216 (PubMed) · PMC4006992 (PubMed Central)
  35. Contribution of lipid-reactive natural killer T cells to obesity-associated inflammation and insulin resistance. Wu L, Van Kaer L (2013) Adipocyte 2(1): 12-16
    › Primary publication · 23700548 (PubMed) · PMC3661135 (PubMed Central)
  36. Mycobacterium tuberculosis controls microRNA-99b (miR-99b) expression in infected murine dendritic cells to modulate host immunity. Singh Y, Kaul V, Mehra A, Chatterjee S, Tousif S, Dwivedi VP, Suar M, Van Kaer L, Bishai WR, Das G (2013) J Biol Chem 288(7): 5056-61
    › Primary publication · 23233675 (PubMed) · PMC3576108 (PubMed Central)
  37. An important role of prostanoid receptor EP2 in host resistance to Mycobacterium tuberculosis infection in mice. Kaul V, Bhattacharya D, Singh Y, Van Kaer L, Peters-Golden M, Bishai WR, Das G (2012) J Infect Dis 206(12): 1816-25
    › Primary publication · 23033144 (PubMed) · PMC3502376 (PubMed Central)
  38. Natural killer T cells are required for lipopolysaccharide-mediated enhancement of atherosclerosis in apolipoprotein E-deficient mice. Andoh Y, Ogura H, Satoh M, Shimano K, Okuno H, Fujii S, Ishimori N, Eshima K, Tamauchi H, Otani T, Nakai Y, Van Kaer L, Tsutsui H, Onoé K, Iwabuchi K (2013) Immunobiology 218(4): 561-9
    › Primary publication · 22954709 (PubMed) · PMC3535521 (PubMed Central)
  39. NK cells inhibit T-bet-deficient, autoreactive Th17 cells. Wu W, Shi S, Ljunggren HG, Cava AL, Van Kaer L, Shi FD, Liu R (2012) Scand J Immunol 76(6): 559-66
    › Primary publication · 22928727 (PubMed) · PMC3600979 (PubMed Central)
  40. Mycobacterium tuberculosis directs T helper 2 cell differentiation by inducing interleukin-1β production in dendritic cells. Dwivedi VP, Bhattacharya D, Chatterjee S, Prasad DV, Chattopadhyay D, Van Kaer L, Bishai WR, Das G (2012) J Biol Chem 287(40): 33656-63
    › Primary publication · 22810226 (PubMed) · PMC3460463 (PubMed Central)
  41. Prostanoid receptor 2 signaling protects T helper 2 cells from BALB/c mice against activation-induced cell death. Kaul V, Van Kaer L, Das G, Das J (2012) J Biol Chem 287(30): 25434-9
    › Primary publication · 22654101 (PubMed) · PMC3408175 (PubMed Central)
  42. Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice. Wu L, Parekh VV, Gabriel CL, Bracy DP, Marks-Shulman PA, Tamboli RA, Kim S, Mendez-Fernandez YV, Besra GS, Lomenick JP, Williams B, Wasserman DH, Van Kaer L (2012) Proc Natl Acad Sci U S A 109(19): E1143-52
    › Primary publication · 22493234 (PubMed) · PMC3358828 (PubMed Central)
  43. Transforming growth factor-β protein inversely regulates in vivo differentiation of interleukin-17 (IL-17)-producing CD4+ and CD8+ T cells. Dwivedi VP, Tousif S, Bhattacharya D, Prasad DV, Van Kaer L, Das J, Das G (2012) J Biol Chem 287(5): 2943-7
    › Primary publication · 22170065 (PubMed) · PMC3270951 (PubMed Central)
  44. CD4+ T cell-derived novel peptide Thp5 induces interleukin-4 production in CD4+ T cells to direct T helper 2 cell differentiation. Khan MM, Chatterjee S, Dwivedi VP, Pandey NK, Singh Y, Tousif S, Bhavesh NS, Van Kaer L, Das J, Das G (2012) J Biol Chem 287(4): 2830-5
    › Primary publication · 22130674 (PubMed) · PMC3268440 (PubMed Central)
  45. Early secreted antigen ESAT-6 of Mycobacterium tuberculosis promotes protective T helper 17 cell responses in a toll-like receptor-2-dependent manner. Chatterjee S, Dwivedi VP, Singh Y, Siddiqui I, Sharma P, Van Kaer L, Chattopadhyay D, Das G (2011) PLoS Pathog 7(11): e1002378
    › Primary publication · 22102818 (PubMed) · PMC3213116 (PubMed Central)
  46. IL-15 regulates homeostasis and terminal maturation of NKT cells. Gordy LE, Bezbradica JS, Flyak AI, Spencer CT, Dunkle A, Sun J, Stanic AK, Boothby MR, He YW, Zhao Z, Van Kaer L, Joyce S (2011) J Immunol 187(12): 6335-45
    › Primary publication · 22084435 (PubMed) · PMC3237743 (PubMed Central)
  47. Mucosal memory CD8⁺ T cells are selected in the periphery by an MHC class I molecule. Huang Y, Park Y, Wang-Zhu Y, Larange A, Arens R, Bernardo I, Olivares-Villagómez D, Herndler-Brandstetter D, Abraham N, Grubeck-Loebenstein B, Schoenberger SP, Van Kaer L, Kronenberg M, Teitell MA, Cheroutre H (2011) Nat Immunol 12(11): 1086-95
    › Primary publication · 21964609 (PubMed) · PMC3197978 (PubMed Central)
  48. Organ-specific features of natural killer cells. Shi FD, Ljunggren HG, La Cava A, Van Kaer L (2011) Nat Rev Immunol 11(10): 658-71
    › Primary publication · 21941294 (PubMed) · PMC3620656 (PubMed Central)
  49. Intestinal epithelial cells modulate CD4 T cell responses via the thymus leukemia antigen. Olivares-Villagómez D, Algood HM, Singh K, Parekh VV, Ryan KE, Piazuelo MB, Wilson KT, Van Kaer L (2011) J Immunol 187(8): 4051-60
    › Primary publication · 21900182 (PubMed) · PMC3186831 (PubMed Central)
  50. Deletion of the G6pc2 gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein does not affect the progression or incidence of type 1 diabetes in NOD/ShiLtJ mice. Oeser JK, Parekh VV, Wang Y, Jegadeesh NK, Sarkar SA, Wong R, Lee CE, Pound LD, Hutton JC, Van Kaer L, O'Brien RM (2011) Diabetes 60(11): 2922-7
    › Primary publication · 21896930 (PubMed) · PMC3198073 (PubMed Central)
  51. T cells from Programmed Death-1 deficient mice respond poorly to Mycobacterium tuberculosis infection. Tousif S, Singh Y, Prasad DV, Sharma P, Van Kaer L, Das G (2011) PLoS One 6(5): e19864
    › Primary publication · 21589883 (PubMed) · PMC3093409 (PubMed Central)
  52. Proteasomes, TAP, and endoplasmic reticulum-associated aminopeptidase associated with antigen processing control CD4+ Th cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigens. Dragovic SM, Hill T, Christianson GJ, Kim S, Elliott T, Scott D, Roopenian DC, Van Kaer L, Joyce S (2011) J Immunol 186(12): 6683-92
    › Primary publication · 21572029 (PubMed) · PMC3537507 (PubMed Central)
  53. Interleukin-2/interleukin-2 antibody therapy induces target organ natural killer cells that inhibit central nervous system inflammation. Hao J, Campagnolo D, Liu R, Piao W, Shi S, Hu B, Xiang R, Zhou Q, Vollmer T, Van Kaer L, La Cava A, Shi FD (2011) Ann Neurol 69(4): 721-34
    › Primary publication · 21425186 (PubMed) · PMC3082615 (PubMed Central)
  54. Natural killer T cells in health and disease. Wu L, Van Kaer L (2011) Front Biosci (Schol Ed) 3(1): 236-51
    › Primary publication · 21196373 (PubMed) · PMC3626278 (PubMed Central)
  55. Invariant NK T cells: potential for immunotherapeutic targeting with glycolipid antigens. Van Kaer L, Parekh VV, Wu L (2011) Immunotherapy 3(1): 59-75
    › Primary publication · 21174558 (PubMed)
  56. Mycobacterium tuberculosis evades host immunity by recruiting mesenchymal stem cells. Raghuvanshi S, Sharma P, Singh S, Van Kaer L, Das G (2010) Proc Natl Acad Sci U S A 107(50): 21653-8
    › Primary publication · 21135221 (PubMed) · PMC3003090 (PubMed Central)
  57. NKT cell costimulation: experimental progress and therapeutic promise. van den Heuvel MJ, Garg N, Van Kaer L, Haeryfar SM (2011) Trends Mol Med 17(2): 65-77
    › Primary publication · 21087900 (PubMed) · PMC3616392 (PubMed Central)
  58. Engagement of glycosylphosphatidylinositol-anchored proteins results in enhanced mouse and human invariant natural killer T cell responses. Mannik LA, Chin-Yee I, Sharif S, Van Kaer L, Delovitch TL, Haeryfar SM (2011) Immunology 132(3): 361-75
    › Primary publication · 21070234 (PubMed) · PMC3044902 (PubMed Central)
  59. Glatiramer acetate for treatment of MS: regulatory B cells join the cast of players. Van Kaer L (2011) Exp Neurol 227(1): 19-23
    › Primary publication · 20969865 (PubMed) · PMC3018666 (PubMed Central)
  60. Comeback kids: CD8(+) suppressor T cells are back in the game. Van Kaer L (2010) J Clin Invest 120(10): 3432-4
    › Primary publication · 20877006 (PubMed) · PMC2947243 (PubMed Central)
  61. KSR1 protects from interleukin-10 deficiency-induced colitis in mice by suppressing T-lymphocyte interferon-γ production. Goettel JA, Scott Algood HM, Olivares-Villagómez D, Washington MK, Chaturvedi R, Wilson KT, Van Kaer L, Polk DB (2011) Gastroenterology 140(1): 265-74
    › Primary publication · 20875416 (PubMed) · PMC3008308 (PubMed Central)
  62. TL and CD8αα: Enigmatic partners in mucosal immunity. Olivares-Villagómez D, Van Kaer L (2010) Immunol Lett 134(1): 1-6
    › Primary publication · 20850477 (PubMed) · PMC2967663 (PubMed Central)
  63. Role of invariant natural killer T cells in immune regulation and as potential therapeutic targets in autoimmune disease. Van Kaer L (2006) Expert Rev Clin Immunol 2(5): 745-57
    › Primary publication · 20477630 (PubMed)
  64. Human invariant Valpha24+ natural killer T cells acquire regulatory functions by interacting with IL-10-treated dendritic cells. Yamaura A, Hotta C, Nakazawa M, Van Kaer L, Minami M (2008) Blood 111(8): 4254-63
    › Primary publication · 18270329 (PubMed)
  65. Effect of high fat diet on NKT cell function and NKT cell-mediated regulation of Th1 responses. Miyazaki Y, Iwabuchi K, Iwata D, Miyazaki A, Kon Y, Niino M, Kikuchi S, Yanagawa Y, Kaer LV, Sasaki H, Onoé K (2008) Scand J Immunol 67(3): 230-7
    › Primary publication · 18226013 (PubMed)
  66. Cutting edge: Guillain-Barre syndrome-associated IgG responses to gangliosides are generated independently of CD1 function in mice. Matsumoto Y, Yuki N, Van Kaer L, Furukawa K, Hirata K, Sugita M (2008) J Immunol 180(1): 39-43
    › Primary publication · 18097001 (PubMed)