Bruce Damon
Last active: 3/3/2020


Dr. Bruce Damon, PhD is appointed as an Associate Professor of Radiology and Radiological Sciences, Biomedical Engineering, and Molecular Physiology and Biophysics at Vanderbilt University.

The objectives of his research program are to develop new magnetic resonance imaging methods for assessing neuromuscular function in vivo and to implement these methods in applied physiology and clinical studies. Particular areas of interest include the understanding of MRI contrast mechanisms, biomarker development, diffusion-tensor MRI studies of muscle structure, spatial tagging studies of muscle strain development during contraction, and the use of MRI, NIRS, and ultrasound methods to study muscle perfusion and metabolism. He has applied these methods in patient populations that include diabetes, obesity, inflammatory myopathies, and muscular dystrophies. 

In addition, Dr. Damon is very involved in the undergraduate and graduate teaching missions at Vanderbilt.  He serves as the Director of Educational and Training Program at the Vanderbilt University Institute of Imaging Science and as the Director of the Chemical and Physical Biology Program. His undergraduate teaching at Vanderbilt has included courses in Systems Physiology and Neuromuscular Mechanics and Physiology; graduate teaching has included courses in Experimental NMR Methods and Experimental Design for the Biomedical Sciences.  He has served as the primary mentor to more than 35 persons at educational ranging from high school students to university faculty.



The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Cold exposure induces dynamic, heterogeneous alterations in human brown adipose tissue lipid content. Coolbaugh CL, Damon BM, Bush EC, Welch EB, Towse TF (2019) Sci Rep 9(1): 13600
    › Primary publication · 31537877 (PubMed) · PMC6753098 (PubMed Central)
  2. MR fingerprinting with simultaneous T, T, and fat signal fraction estimation with integrated B correction reduces bias in water T and T estimates. Ostenson J, Damon BM, Welch EB (2019) Magn Reson Imaging : 7-19
    › Primary publication · 30910696 (PubMed) · PMC6581466 (PubMed Central)
  3. Exploration of New Contrasts, Targets, and MR Imaging and Spectroscopy Techniques for Neuromuscular Disease - A Workshop Report of Working Group 3 of the Biomedicine and Molecular Biosciences COST Action BM1304 MYO-MRI. Strijkers GJ, Araujo ECA, Azzabou N, Bendahan D, Blamire A, Burakiewicz J, Carlier PG, Damon B, Deligianni X, Froeling M, Heerschap A, Hollingsworth KG, Hooijmans MT, Karampinos DC, Loudos G, Madelin G, Marty B, Nagel AM, Nederveen AJ, Nelissen JL, Santini F, Scheidegger O, Schick F, Sinclair C, Sinkus R, de Sousa PL, Straub V, Walter G, Kan HE (2019) J Neuromuscul Dis 6(1): 1-30
    › Primary publication · 30714967 (PubMed) · PMC6398566 (PubMed Central)
  4. Fat-Water Phantoms for Magnetic Resonance Imaging Validation: A Flexible and Scalable Protocol. Bush EC, Gifford A, Coolbaugh CL, Towse TF, Damon BM, Welch EB (2018) J Vis Exp (139)
    › Primary publication · 30247483 (PubMed) · PMC6235120 (PubMed Central)
  5. Increased Number of Circulating CD8/CD26 T Cells in the Blood of Duchenne Muscular Dystrophy Patients Is Associated with Augmented Binding of Adenosine Deaminase and Higher Muscular Strength Scores. Soslow JH, Markham LW, Burnette WB, Galindo CL, Feoktistov I, Raucci FJ, Damon BM, Sawyer DB, Ryzhov S (2017) Front Pharmacol : 914
    › Primary publication · 29326589 (PubMed) · PMC5741593 (PubMed Central)
  6. Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease. Damon BM, Li K, Dortch RD, Welch EB, Park JH, Buck AK, Towse TF, Does MD, Gochberg DF, Bryant ND (2016) J Vis Exp (118)
    › Primary publication · 28060254 (PubMed) · PMC5226425 (PubMed Central)
  7. Post-contractile BOLD contrast in skeletal muscle at 7‚ÄČT reveals inter-individual heterogeneity in the physiological responses to muscle contraction. Towse TF, Elder CP, Bush EC, Klockenkemper SW, Bullock JT, Dortch RD, Damon BM (2016) NMR Biomed 29(12): 1720-1728
    › Primary publication · 27753155 (PubMed) · PMC6594689 (PubMed Central)
  8. Cellular and Morphological Alterations in the Vastus Lateralis Muscle as the Result of ACL Injury and Reconstruction. Noehren B, Andersen A, Hardy P, Johnson DL, Ireland ML, Thompson KL, Damon B (2016) J Bone Joint Surg Am 98(18): 1541-7
    › Primary publication · 27655981 (PubMed) · PMC5026157 (PubMed Central)
  9. FloWave.US: validated, open-source, and flexible software for ultrasound blood flow analysis. Coolbaugh CL, Bush EC, Caskey CF, Damon BM, Towse TF (2016) J Appl Physiol (1985) 121(4): 849-857
    › Primary publication · 27516540 (PubMed) · PMC5142308 (PubMed Central)
  10. Statement of Retraction. Hepatic Glucagon Action Is Essential for Exercise-Induced Reversal of Mouse Fatty Liver. Diabetes 2011;60:2720-2729. DOI: 10.2337/db11-0455. Berglund ED, Lustig DG, Baheza RA, Hasenour CM, Lee-Young RS, Donahue EP, Lynes SE, Swift LL, Charron MJ, Damon BM, Wasserman DH (2016) Diabetes 65(8): 2463
    › Primary publication · 27456624 (PubMed) · PMC5223407 (PubMed Central)
  11. Magnetic resonance imaging of skeletal muscle disease. Damon BM, Li K, Bryant ND (2016) Handb Clin Neurol : 827-42
    › Primary publication · 27430444 (PubMed)
  12. Skeletal muscle diffusion tensor-MRI fiber tracking: rationale, data acquisition and analysis methods, applications and future directions. Damon BM, Froeling M, Buck AK, Oudeman J, Ding Z, Nederveen AJ, Bush EC, Strijkers GJ (2017) NMR Biomed 30(3)
    › Primary publication · 27257975 (PubMed) · PMC5136336 (PubMed Central)
  13. Increased myocardial native T1 and extracellular volume in patients with Duchenne muscular dystrophy. Soslow JH, Damon SM, Crum K, Lawson MA, Slaughter JC, Xu M, Arai AE, Sawyer DB, Parra DA, Damon BM, Markham LW (2016) J Cardiovasc Magn Reson : 5
    › Primary publication · 26795569 (PubMed) · PMC4722665 (PubMed Central)
  14. Evaluation of skeletal muscle DTI in patients with duchenne muscular dystrophy. Hooijmans MT, Damon BM, Froeling M, Versluis MJ, Burakiewicz J, Verschuuren JJ, Niks EH, Webb AG, Kan HE (2015) NMR Biomed 28(11): 1589-97
    › Primary publication · 26449628 (PubMed) · PMC4670831 (PubMed Central)
  15. Matching of postcontraction perfusion to oxygen consumption across submaximal contraction intensities in exercising humans. Buck AK, Elder CP, Donahue MJ, Damon BM (2015) J Appl Physiol (1985) 119(3): 280-9
    › Primary publication · 26066829 (PubMed) · PMC4526707 (PubMed Central)
  16. A rapid approach for quantitative magnetization transfer imaging in thigh muscles using the pulsed saturation method. Li K, Dortch RD, Kroop SF, Huston JW, Gochberg DF, Park JH, Damon BM (2015) Magn Reson Imaging 33(6): 709-17
    › Primary publication · 25839394 (PubMed) · PMC4755108 (PubMed Central)
  17. Diffusion-Tensor MRI Based Skeletal Muscle Fiber Tracking. Damon BM, Buck AK, Ding Z (2011) Imaging Med 3(6): 675-687
    › Primary publication · 25429308 (PubMed) · PMC4241547 (PubMed Central)
  18. Evaluation of a multiple spin- and gradient-echo (SAGE) EPI acquisition with SENSE acceleration: applications for perfusion imaging in and outside the brain. Skinner JT, Robison RK, Elder CP, Newton AT, Damon BM, Quarles CC (2014) Magn Reson Imaging 32(10): 1171-80
    › Primary publication · 25179133 (PubMed) · PMC4253546 (PubMed Central)
  19. Evaluation of post-contrast myocardial t1 in duchenne muscular dystrophy using cardiac magnetic resonance imaging. Soslow JH, Damon BM, Saville BR, Lu Z, Burnette WB, Lawson MA, Parra DA, Sawyer DB, Markham LW (2015) Pediatr Cardiol 36(1): 49-56
    › Primary publication · 25070387 (PubMed) · PMC4439095 (PubMed Central)
  20. Multi-parametric MRI characterization of healthy human thigh muscles at 3.0 T - relaxation, magnetization transfer, fat/water, and diffusion tensor imaging. Li K, Dortch RD, Welch EB, Bryant ND, Buck AK, Towse TF, Gochberg DF, Does MD, Damon BM, Park JH (2014) NMR Biomed 27(9): 1070-84
    › Primary publication · 25066274 (PubMed) · PMC4153695 (PubMed Central)
  21. Multi-parametric MRI characterization of inflammation in murine skeletal muscle. Bryant ND, Li K, Does MD, Barnes S, Gochberg DF, Yankeelov TE, Park JH, Damon BM (2014) NMR Biomed 27(6): 716-25
    › Primary publication · 24777935 (PubMed) · PMC4134016 (PubMed Central)
  22. Comparison of twice refocused spin echo versus stimulated echo diffusion tensor imaging for tracking muscle fibers. Noehren B, Andersen A, Feiweier T, Damon B, Hardy P (2015) J Magn Reson Imaging 41(3): 624-32
    › Primary publication · 24554376 (PubMed) · PMC4231024 (PubMed Central)
  23. Buckle fractures in children: Is urgent treatment necessary? Bennett DL, Mencio GA, Hernanz-Schulman M, Nealy BJ, Damon B, Kan JH (2009) J Fam Pract 58(10): E1-6
    › Primary publication · 19874727 (PubMed)
  24. MRI measures of perfusion-related changes in human skeletal muscle during progressive contractions. Wigmore DM, Damon BM, Pober DM, Kent-Braun JA (2004) J Appl Physiol (1985) 97(6): 2385-94
    › Primary publication · 15298991 (PubMed)
  25. Comparison of MRI with EMG to study muscle activity associated with dynamic plantar flexion. Price TB, Kamen G, Damon BM, Knight CA, Applegate B, Gore JC, Eward K, Signorile JF (2003) Magn Reson Imaging 21(8): 853-61
    › Primary publication · 14599535 (PubMed)
  26. Early postexercise muscle glycogen recovery is enhanced with a carbohydrate-protein supplement. Ivy JL, Goforth HW, Damon BM, McCauley TR, Parsons EC, Price TB (2002) J Appl Physiol (1985) 93(4): 1337-44
    › Primary publication · 12235033 (PubMed)
  27. Validation of diffusion tensor MRI-based muscle fiber tracking. Damon BM, Ding Z, Anderson AW, Freyer AS, Gore JC (2002) Magn Reson Med 48(1): 97-104
    › Primary publication · 12111936 (PubMed)
  28. Intracellular acidification and volume increases explain R(2) decreases in exercising muscle. Damon BM, Gregory CD, Hall KL, Stark HJ, Gulani V, Dawson MJ (2002) Magn Reson Med 47(1): 14-23
    › Primary publication · 11754438 (PubMed)