Damian Maseda
Post-doctoral Fellow
Last active: 10/12/2016

Profile

I am a broadly-trained immunologist and biologist currently doing postdoctoral work on B and T cell function in autoimmune diseases. In my main project at the moment I am investigating how prostaglandins integrate the inflammatory processes and immune responses in Inflammatory Bowel Diseases.

My strongest expertise areas are:

- Lymphocyte biology in autoimmune disorders.
- Regulatory mechanisms in immune responses.
- T and B cell development.
- Developmental biology.

Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Transcription factor KLF2 regulates homeostatic NK cell proliferation and survival. Rabacal W, Pabbisetty SK, Hoek KL, Cendron D, Guo Y, Maseda D, Sebzda E (2016) Proc Natl Acad Sci U S A 113(19): 5370-5
    › Primary publication · 27114551 (PubMed) · PMC4868471 (PubMed Central)
  2. Bruton's Tyrosine Kinase Deficiency Inhibits Autoimmune Arthritis in Mice but Fails to Block Immune Complex-Mediated Inflammatory Arthritis. Nyhoff LE, Barron BL, Johnson EM, Bonami RH, Maseda D, Fensterheim BA, Han W, Blackwell TS, Crofford LJ, Kendall PL (2016) Arthritis Rheumatol 68(8): 1856-68
    › Primary publication · 26945549 (PubMed)
  3. KLF2 is a rate-limiting transcription factor that can be targeted to enhance regulatory T-cell production. Pabbisetty SK, Rabacal W, Maseda D, Cendron D, Collins PL, Hoek KL, Parekh VV, Aune TM, Sebzda E (2014) Proc Natl Acad Sci U S A 111(26): 9579-84
    › Primary publication · 24979767 (PubMed) · PMC4084438 (PubMed Central)
  4. Regulation of B lymphocytes and plasma cells by innate immune mechanisms and stromal cells in rheumatoid arthritis. Maseda D, Bonami RH, Crofford LJ (2014) Expert Rev Clin Immunol 10(6): 747-62
    › Primary publication · 24734886 (PubMed) · PMC5073792 (PubMed Central)
  5. Peritoneal cavity regulatory B cells (B10 cells) modulate IFN-γ+CD4+ T cell numbers during colitis development in mice. Maseda D, Candando KM, Smith SH, Kalampokis I, Weaver CT, Plevy SE, Poe JC, Tedder TF (2013) J Immunol 191(5): 2780-95
    › Primary publication · 23918988 (PubMed) · PMC3770313 (PubMed Central)
  6. Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo. Maseda D, Smith SH, DiLillo DJ, Bryant JM, Candando KM, Weaver CT, Tedder TF (2012) J Immunol 188(3): 1036-48
    › Primary publication · 22198952 (PubMed) · PMC3262922 (PubMed Central)
  7. The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis. Neubert K, Meister S, Moser K, Weisel F, Maseda D, Amann K, Wiethe C, Winkler TH, Kalden JR, Manz RA, Voll RE (2008) Nat Med 14(7): 748-55
    › Primary publication · 18542049 (PubMed)
  8. Proteasome inhibition drastically but reversibly impairs murine lymphocyte development. Maseda D, Meister S, Neubert K, Herrmann M, Voll RE (2008) Cell Death Differ 15(3): 600-12
    › Primary publication · 18188168 (PubMed)
  9. Apoptotic cells selectively suppress the Th1 cytokine interferon gamma in stimulated human peripheral blood mononuclear cells and shift the Th1/Th2 balance towards Th2. Girkontaite I, Urbonaviciute V, Maseda D, Neubert K, Herrmann M, Voll RE (2007) Autoimmunity 40(4): 327-30
    › Primary publication · 17516220 (PubMed)
  10. Ray-interray interactions during fin regeneration of Danio rerio. Murciano C, Fernández TD, Durán I, Maseda D, Ruiz-Sánchez J, Becerra J, Akimenko MA, Marí-Beffa M (2002) Dev Biol 252(2): 214-24
    › Primary publication · 12482711 (PubMed)