Rupesh Chaturvedi, Ph.D.

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Publications

The following timeline graph is generated from all co-authored publications.

1. Matrix metalloproteinase 7 restrains Helicobacter pylori-induced gastric inflammation and premalignant lesions in the stomach by altering macrophage polarization. Krakowiak MS, Noto JM, Piazuelo MB, Hardbower DM, Romero-Gallo J, Delgado A, Chaturvedi R, Correa P, Wilson KT, Peek RM (2015) Oncogene 34(14): 1865-71
   › Primary publication · 24837365 (PubMed) · PMC4237684 (PubMed Central)
2. Peroxisome proliferator-activated receptor δ promotes colonic inflammation and tumor growth. Wang D, Fu L, Ning W, Guo L, Sun X, Dey SK, Chaturvedi R, Wilson KT, DuBois RN (2014) Proc Natl Acad Sci U S A 111(19): 7084-9
   › Primary publication · 24763687 (PubMed) · PMC4024916 (PubMed Central)
3. Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression, and protects from colitis. Ahmad R, Chaturvedi R, Olivares-Villagómez D, Habib T, Asim M, Shivesh P, Polk DB, Wilson KT, Washington MK, Van Kaer L, Dhawan P, Singh AB (2014) Mucosal Immunol 7(6): 1340-53
   › Primary publication · 24670427 (PubMed) · PMC4221190 (PubMed Central)
4. Activation of EGFR and ERBB2 by Helicobacter pylori results in survival of gastric epithelial cells with DNA damage. Chaturvedi R, Asim M, Piazuelo MB, Yan F, Barry DP, Sierra JC, Delgado AG, Hill S, Casero RA, Bravo LE, Dominguez RL, Correa P, Polk DB, Washington MK, Rose KL, Schey KL, Morgan DR, Peek RM, Wilson KT (2014) Gastroenterology 146(7): 1739-51.e14
   › Primary publication · 24530706 (PubMed) · PMC4035375 (PubMed Central)
5. High-throughput multi-analyte Luminex profiling implicates eotaxin-1 in ulcerative colitis. Coburn LA, Horst SN, Chaturvedi R, Brown CT, Allaman MM, Scull BP, Singh K, Piazuelo MB, Chitnavis MV, Hodges ME, Rosen MJ, Williams CS, Slaughter JC, Beaulieu DB, Schwartz DA, Wilson KT (2013) PLoS One 8(12): e82300
   › Primary publication · 24367513 (PubMed) · PMC3867379 (PubMed Central)
6. Strain-specific suppression of microRNA-320 by carcinogenic Helicobacter pylori promotes expression of the antiapoptotic protein Mcl-1. Noto JM, Piazuelo MB, Chaturvedi R, Bartel CA, Thatcher EJ, Delgado A, Romero-Gallo J, Wilson KT, Correa P, Patton JG, Peek RM (2013) Am J Physiol Gastrointest Liver Physiol 305(11): G786-96
   › Primary publication · 24136787 (PubMed) · PMC3882435 (PubMed Central)
7. Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis. Barrett CW, Singh K, Motley AK, Lintel MK, Matafonova E, Bradley AM, Ning W, Poindexter SV, Parang B, Reddy VK, Chaturvedi R, Fingleton BM, Washington MK, Wilson KT, Davies SS, Hill KE, Burk RF, Williams CS (2013) PLoS One 8(7): e67845
   › Primary publication · 23861820 (PubMed) · PMC3701622 (PubMed Central)
8. Spermine oxidase is a regulator of macrophage host response to Helicobacter pylori: enhancement of antimicrobial nitric oxide generation by depletion of spermine. Chaturvedi R, Asim M, Barry DP, Frye JW, Casero RA, Wilson KT (2014) Amino Acids 46(3): 531-42
   › Primary publication · 23820617 (PubMed) · PMC3812355 (PubMed Central)
9. Chronic inflammation and oxidative stress: the smoking gun for Helicobacter pylori-induced gastric cancer? Hardbower DM, de Sablet T, Chaturvedi R, Wilson KT (2013) Gut Microbes 4(6): 475-81
   › Primary publication · 23811829 (PubMed) · PMC3928159 (PubMed Central)
10. Deletion of cationic amino acid transporter 2 exacerbates dextran sulfate sodium colitis and leads to an IL-17-predominant T cell response. Singh K, Coburn LA, Barry DP, Asim M, Scull BP, Allaman MM, Lewis ND, Washington MK, Rosen MJ, Williams CS, Chaturvedi R, Wilson KT (2013) Am J Physiol Gastrointest Liver Physiol 305(3): G225-40
    › Primary publication · 23703655 (PubMed) · PMC3742860 (PubMed Central)
11. Induction of COX-2 expression by Helicobacter pylori is mediated by activation of epidermal growth factor receptor in gastric epithelial cells. Sierra JC, Hobbs S, Chaturvedi R, Yan F, Wilson KT, Peek RM, Polk DB (2013) Am J Physiol Gastrointest Liver Physiol 305(2): G196-203
    › Primary publication · 23681474 (PubMed) · PMC3725681 (PubMed Central)
12. Phylogeographic origin of Helicobacter pylori determines host-adaptive responses upon coculture with gastric epithelial cells. Sheh A, Chaturvedi R, Merrell DS, Correa P, Wilson KT, Fox JG (2013) Infect Immun 81(7): 2468-77
    › Primary publication · 23630959 (PubMed) · PMC3697613 (PubMed Central)
13. Helicobacter pylori promotes the expression of Krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo. Noto JM, Khizanishvili T, Chaturvedi R, Piazuelo MB, Romero-Gallo J, Delgado AG, Khurana SS, Sierra JC, Krishna US, Suarez G, Powell AE, Goldenring JR, Coffey RJ, Yang VW, Correa P, Mills JC, Wilson KT, Peek RM (2013) PLoS One 8(1): e54344
    › Primary publication · 23372710 (PubMed) · PMC3553174 (PubMed Central)
14. STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines. Rosen MJ, Chaturvedi R, Washington MK, Kuhnhein LA, Moore PD, Coggeshall SS, McDonough EM, Weitkamp JH, Singh AB, Coburn LA, Williams CS, Yan F, Van Kaer L, Peebles RS, Wilson KT (2013) J Immunol 190(4): 1849-58
    › Primary publication · 23303670 (PubMed) · PMC3563924 (PubMed Central)
15. Tumor suppressor function of the plasma glutathione peroxidase gpx3 in colitis-associated carcinoma. Barrett CW, Ning W, Chen X, Smith JJ, Washington MK, Hill KE, Coburn LA, Peek RM, Chaturvedi R, Wilson KT, Burk RF, Williams CS (2013) Cancer Res 73(3): 1245-55
    › Primary publication · 23221387 (PubMed) · PMC3563732 (PubMed Central)
16. Haem oxygenase-1 inhibits phosphorylation of the Helicobacter pylori oncoprotein CagA in gastric epithelial cells. Gobert AP, Verriere T, de Sablet T, Peek RM, Chaturvedi R, Wilson KT (2013) Cell Microbiol 15(1): 145-56
    › Primary publication · 23051580 (PubMed) · PMC3524338 (PubMed Central)
17. MTG16 contributes to colonic epithelial integrity in experimental colitis. Williams CS, Bradley AM, Chaturvedi R, Singh K, Piazuelo MB, Chen X, McDonough EM, Schwartz DA, Brown CT, Allaman MM, Coburn LA, Horst SN, Beaulieu DB, Choksi YA, Washington MK, Williams AD, Fisher MA, Zinkel SS, Peek RM, Wilson KT, Hiebert SW (2013) Gut 62(10): 1446-55
    › Primary publication · 22833394 (PubMed) · PMC3663894 (PubMed Central)
18. HER2 as a therapeutic target in the gastric cancer: is it sufficient? Chaturvedi R, Singh AB (2012) Indian J Gastroenterol 31(3): 103-5
    › Primary publication · 22763895 (PubMed) · PMC3692359 (PubMed Central)
19. Spermine oxidase, a polyamine catabolic enzyme that links Helicobacter pylori CagA and gastric cancer risk. Chaturvedi R, de Sablet T, Peek RM, Wilson KT (2012) Gut Microbes 3(1): 48-56
    › Primary publication · 22555547 (PubMed) · PMC3337125 (PubMed Central)
20. L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis. Coburn LA, Gong X, Singh K, Asim M, Scull BP, Allaman MM, Williams CS, Rosen MJ, Washington MK, Barry DP, Piazuelo MB, Casero RA, Chaturvedi R, Zhao Z, Wilson KT (2012) PLoS One 7(3): e33546
    › Primary publication · 22428068 (PubMed) · PMC3299802 (PubMed Central)
21. L-arginine uptake by cationic amino acid transporter 2 is essential for colonic epithelial cell restitution. Singh K, Coburn LA, Barry DP, Boucher JL, Chaturvedi R, Wilson KT (2012) Am J Physiol Gastrointest Liver Physiol 302(9): G1061-73
    › Primary publication · 22361732 (PubMed) · PMC3362080 (PubMed Central)
22. Berberine promotes recovery of colitis and inhibits inflammatory responses in colonic macrophages and epithelial cells in DSS-treated mice. Yan F, Wang L, Shi Y, Cao H, Liu L, Washington MK, Chaturvedi R, Israel DA, Cao H, Wang B, Peek RM, Wilson KT, Polk DB (2012) Am J Physiol Gastrointest Liver Physiol 302(5): G504-14
    › Primary publication · 22173918 (PubMed) · PMC3311435 (PubMed Central)
23. Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells. Peng D, Belkhiri A, Hu T, Chaturvedi R, Asim M, Wilson KT, Zaika A, El-Rifai W (2012) Gut 61(9): 1250-60
    › Primary publication · 22157330 (PubMed) · PMC3419307 (PubMed Central)
24. Disruption of nitric oxide signaling by Helicobacter pylori results in enhanced inflammation by inhibition of heme oxygenase-1. Gobert AP, Asim M, Piazuelo MB, Verriere T, Scull BP, de Sablet T, Glumac A, Lewis ND, Correa P, Peek RM, Chaturvedi R, Wilson KT (2011) J Immunol 187(10): 5370-9
    › Primary publication · 21987660 (PubMed) · PMC3208050 (PubMed Central)
25. Arginine and polyamines in Helicobacter pylori-induced immune dysregulation and gastric carcinogenesis. Chaturvedi R, de Sablet T, Coburn LA, Gobert AP, Wilson KT (2012) Amino Acids 42(2-3): 627-40
    › Primary publication · 21874531 (PubMed) · PMC3258477 (PubMed Central)
26. Spermine oxidase mediates the gastric cancer risk associated with Helicobacter pylori CagA. Chaturvedi R, Asim M, Romero-Gallo J, Barry DP, Hoge S, de Sablet T, Delgado AG, Wroblewski LE, Piazuelo MB, Yan F, Israel DA, Casero RA, Correa P, Gobert AP, Polk DB, Peek RM, Wilson KT (2011) Gastroenterology 141(5): 1696-708.e1-2
    › Primary publication · 21839041 (PubMed) · PMC3202654 (PubMed Central)
27. Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism. Yan F, Cao H, Cover TL, Washington MK, Shi Y, Liu L, Chaturvedi R, Peek RM, Wilson KT, Polk DB (2011) J Clin Invest 121(6): 2242-53
    › Primary publication · 21606592 (PubMed) · PMC3104743 (PubMed Central)
28. Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction. Barry DP, Asim M, Leiman DA, de Sablet T, Singh K, Casero RA, Chaturvedi R, Wilson KT (2011) PLoS One 6(2): e17510
    › Primary publication · 21386987 (PubMed) · PMC3046249 (PubMed Central)
29. Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation. Dhawan P, Ahmad R, Chaturvedi R, Smith JJ, Midha R, Mittal MK, Krishnan M, Chen X, Eschrich S, Yeatman TJ, Harris RC, Washington MK, Wilson KT, Beauchamp RD, Singh AB (2011) Oncogene 30(29): 3234-47
    › Primary publication · 21383692 (PubMed) · PMC3591522 (PubMed Central)
30. Phylogeographic origin of Helicobacter pylori is a determinant of gastric cancer risk. de Sablet T, Piazuelo MB, Shaffer CL, Schneider BG, Asim M, Chaturvedi R, Bravo LE, Sicinschi LA, Delgado AG, Mera RM, Israel DA, Romero-Gallo J, Peek RM, Cover TL, Correa P, Wilson KT (2011) Gut 60(9): 1189-95
    › Primary publication · 21357593 (PubMed) · PMC3133872 (PubMed Central)
31. STAT6 activation in ulcerative colitis: a new target for prevention of IL-13-induced colon epithelial cell dysfunction. Rosen MJ, Frey MR, Washington MK, Chaturvedi R, Kuhnhein LA, Matta P, Revetta FL, Wilson KT, Polk DB (2011) Inflamm Bowel Dis 17(11): 2224-34
    › Primary publication · 21308881 (PubMed) · PMC3120916 (PubMed Central)
32. MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model. Barrett CW, Fingleton B, Williams A, Ning W, Fischer MA, Washington MK, Chaturvedi R, Wilson KT, Hiebert SW, Williams CS (2011) Cancer Res 71(4): 1302-12
    › Primary publication · 21303973 (PubMed) · PMC3150168 (PubMed Central)
33. Immune evasion by Helicobacter pylori is mediated by induction of macrophage arginase II. Lewis ND, Asim M, Barry DP, de Sablet T, Singh K, Piazuelo MB, Gobert AP, Chaturvedi R, Wilson KT (2011) J Immunol 186(6): 3632-41
    › Primary publication · 21296975 (PubMed) · PMC3069806 (PubMed Central)
34. The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis. Singh K, Chaturvedi R, Barry DP, Coburn LA, Asim M, Lewis ND, Piazuelo MB, Washington MK, Vitek MP, Wilson KT (2011) J Biol Chem 286(5): 3839-50
    › Primary publication · 21115487 (PubMed) · PMC3030385 (PubMed Central)
35. KSR1 protects from interleukin-10 deficiency-induced colitis in mice by suppressing T-lymphocyte interferon-γ production. Goettel JA, Scott Algood HM, Olivares-Villagómez D, Washington MK, Chaturvedi R, Wilson KT, Van Kaer L, Polk DB (2011) Gastroenterology 140(1): 265-74
    › Primary publication · 20875416 (PubMed) · PMC3008308 (PubMed Central)
36. Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production. Chaturvedi R, Asim M, Hoge S, Lewis ND, Singh K, Barry DP, de Sablet T, Piazuelo MB, Sarvaria AR, Cheng Y, Closs EI, Casero RA, Gobert AP, Wilson KT (2010) Gastroenterology 139(5): 1686-98, 1698.e1-6
    › Primary publication · 20600019 (PubMed) · PMC2967614 (PubMed Central)
37. The enigma of Helicobacter pylori infection and gastric cancer. Ghoshal UC, Chaturvedi R, Correa P (2010) Indian J Gastroenterol 29(3): 95-100
    › Primary publication · 20585917 (PubMed) · PMC3217495 (PubMed Central)
38. Helicobacter pylori induces ERK-dependent formation of a phospho-c-Fos c-Jun activator protein-1 complex that causes apoptosis in macrophages. Asim M, Chaturvedi R, Hoge S, Lewis ND, Singh K, Barry DP, Algood HS, de Sablet T, Gobert AP, Wilson KT (2010) J Biol Chem 285(26): 20343-57
    › Primary publication · 20410304 (PubMed) · PMC2888446 (PubMed Central)
39. Increased expression and cellular localization of spermine oxidase in ulcerative colitis and relationship to disease activity. Hong SK, Chaturvedi R, Piazuelo MB, Coburn LA, Williams CS, Delgado AG, Casero RA, Schwartz DA, Wilson KT (2010) Inflamm Bowel Dis 16(9): 1557-66
    › Primary publication · 20127992 (PubMed) · PMC2894261 (PubMed Central)
40. Arginase II restricts host defense to Helicobacter pylori by attenuating inducible nitric oxide synthase translation in macrophages. Lewis ND, Asim M, Barry DP, Singh K, de Sablet T, Boucher JL, Gobert AP, Chaturvedi R, Wilson KT (2010) J Immunol 184(5): 2572-82
    › Primary publication · 20097867 (PubMed) · PMC2841360 (PubMed Central)
41. Matrix metalloproteinase-7 and premalignant host responses in Helicobacter pylori-infected mice. Ogden SR, Noto JM, Allen SS, Patel DA, Romero-Gallo J, Washington MK, Fingleton B, Israel DA, Lewis ND, Wilson KT, Chaturvedi R, Zhao Z, Shyr Y, Peek RM (2010) Cancer Res 70(1): 30-5
    › Primary publication · 20048070 (PubMed) · PMC2804939 (PubMed Central)
42. Increased serum levels of L-arginine in ulcerative colitis and correlation with disease severity. Hong SK, Maltz BE, Coburn LA, Slaughter JC, Chaturvedi R, Schwartz DA, Wilson KT (2010) Inflamm Bowel Dis 16(1): 105-11
    › Primary publication · 19637336 (PubMed) · PMC2795785 (PubMed Central)
43. Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis. Yan F, Cao H, Chaturvedi R, Krishna U, Hobbs SS, Dempsey PJ, Peek RM, Cover TL, Washington MK, Wilson KT, Polk DB (2009) Gastroenterology 136(4): 1297-1307, e1-3
    › Primary publication · 19250983 (PubMed) · PMC2878739 (PubMed Central)
44. Regulation of the Helicobacter pylori cellular receptor decay-accelerating factor. O'Brien DP, Romero-Gallo J, Schneider BG, Chaturvedi R, Delgado A, Harris EJ, Krishna U, Ogden SR, Israel DA, Wilson KT, Peek RM (2008) J Biol Chem 283(35): 23922-30
    › Primary publication · 18579524 (PubMed) · PMC2527108 (PubMed Central)

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