Aaron Fidler
Program Manager, Vanderbilt Center for Matrix Biology, Assistant Professor, Department of Medicine
Last active: 3/12/2019

Profile

Research Assistant Professor in the Billy G Hudson Lab in the Department of Medicine/Division of Nephrology.

My studies revolve around the origins of collagen IV, basement membranes, and other BM components, and their evolutionary roles in enabling animal multicellularity. 

Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Unicellular ancestry and mechanisms of diversification of Goodpasture antigen-binding protein. Darris C, Revert F, Revert-Ros F, Gozalbo-Rovira R, Feigley A, Fidler A, Lopez-Pascual E, Saus J, Hudson BG (2019) J Biol Chem 294(3): 759-769
    › Primary publication · 30377252 (PubMed) · PMC6341388 (PubMed Central)
  2. The triple helix of collagens - an ancient protein structure that enabled animal multicellularity and tissue evolution. Fidler AL, Boudko SP, Rokas A, Hudson BG (2018) J Cell Sci 131(7)
    › Primary publication · 29632050 (PubMed) · PMC5963836 (PubMed Central)
  3. Collagen IV and basement membrane at the evolutionary dawn of metazoan tissues. Fidler AL, Darris CE, Chetyrkin SV, Pedchenko VK, Boudko SP, Brown KL, Gray Jerome W, Hudson JK, Rokas A, Hudson BG (2017) Elife
    › Primary publication · 28418331 (PubMed) · PMC5395295 (PubMed Central)
  4. A unique covalent bond in basement membrane is a primordial innovation for tissue evolution. Fidler AL, Vanacore RM, Chetyrkin SV, Pedchenko VK, Bhave G, Yin VP, Stothers CL, Rose KL, McDonald WH, Clark TA, Borza DB, Steele RE, Ivy MT, Aspirnauts, Hudson JK, Hudson BG (2014) Proc Natl Acad Sci U S A 111(1): 331-6
    › Primary publication · 24344311 (PubMed) · PMC3890831 (PubMed Central)

Featured Affiliation

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Contact Information

1161 21st Avenue S
B-3102 Medical Center North
Nashville, TN 37232
United States
6069232039 (p)
Email

Keywords & MeSH Terms

MeSH terms are retrieved from PubMed records. Learn more.

Key: MeSH Term Keyword

Amino Acid Sequence Animals basement membrane Basement Membrane Biochemistry Biological Evolution Collagen Collagen Type IV Cross-Linking Reagents ctenophora Ctenophora Drosophila melanogaster Evolution Evolution, Molecular Extracellular Matrix Extracellular Matrix Proteins Heme Imines Mass Spectrometry Matrix Biology Molecular Sequence Data Peptides Peroxidase Peroxidases Protein Structure, Tertiary Sequence Analysis, RNA Sequence Homology, Amino Acid Sulfilimine Sulfur Compounds Zebrafish