Darren Tyson
Assistant Professor
Last active: 4/20/2016

Darren R Tyson, Ph.D.

Official Affiliation: Cancer Biology

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Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCĪ± invasive signaling axis. Hoshino D, Jourquin J, Emmons SW, Miller T, Goldgof M, Costello K, Tyson DR, Brown B, Lu Y, Prasad NK, Zhang B, Mills GB, Yarbrough WG, Quaranta V, Seiki M, Weaver AM (2012) Sci Signal 5(241): ra66
    › Primary publication · 22969158 (PubMed) · PMC3583194 (PubMed Central)
  2. Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data. Tyson DR, Garbett SP, Frick PL, Quaranta V (2012) Nat Methods 9(9): 923-8
    › Primary publication · 22886092 (PubMed) · PMC3459330 (PubMed Central)
  3. The contribution of age structure to cell population responses to targeted therapeutics. Gabriel P, Garbett SP, Quaranta V, Tyson DR, Webb GF (2012) J Theor Biol : 19-27
    › Primary publication · 22796330 (PubMed) · PMC3592383 (PubMed Central)
  4. Composite thin film and electrospun biomaterials for urologic tissue reconstruction. Kundu AK, Gelman J, Tyson DR (2011) Biotechnol Bioeng 108(1): 207-15
    › Primary publication · 20830673 (PubMed)
  5. Trait variability of cancer cells quantified by high-content automated microscopy of single cells. Quaranta V, Tyson DR, Garbett SP, Weidow B, Harris MP, Georgescu W (2009) Methods Enzymol : 23-57
    › Primary publication · 19897088 (PubMed) · PMC2915824 (PubMed Central)
  6. Loss of annexin A1 disrupts normal prostate glandular structure by inducing autocrine IL-6 signaling. Inokuchi J, Lau A, Tyson DR, Ornstein DK (2009) Carcinogenesis 30(7): 1082-8
    › Primary publication · 19351789 (PubMed) · PMC2704280 (PubMed Central)
  7. Annexin A2 positively contributes to the malignant phenotype and secretion of IL-6 in DU145 prostate cancer cells. Inokuchi J, Narula N, Yee DS, Skarecky DW, Lau A, Ornstein DK, Tyson DR (2009) Int J Cancer 124(1): 68-74
    › Primary publication · 18924133 (PubMed)
  8. Proteomics of cancer of hormone-dependent tissues. Tyson DR, Ornstein DK (2008) Adv Exp Med Biol : 133-47
    › Primary publication · 18637489 (PubMed)
  9. Culture requirements of prostatic epithelial cell lines for acinar morphogenesis and lumen formation in vitro: role of extracellular calcium. Tyson DR, Inokuchi J, Tsunoda T, Lau A, Ornstein DK (2007) Prostate 67(15): 1601-13
    › Primary publication · 17705248 (PubMed)
  10. The impact of altered annexin I protein levels on apoptosis and signal transduction pathways in prostate cancer cells. Hsiang CH, Tunoda T, Whang YE, Tyson DR, Ornstein DK (2006) Prostate 66(13): 1413-24
    › Primary publication · 16741918 (PubMed)
  11. Proteomics for the identification of new prostate cancer biomarkers. Ornstein DK, Tyson DR (2006) Urol Oncol 24(3): 231-6
    › Primary publication · 16678055 (PubMed)
  12. O-sulfonation of serine and threonine: mass spectrometric detection and characterization of a new posttranslational modification in diverse proteins throughout the eukaryotes. Medzihradszky KF, Darula Z, Perlson E, Fainzilber M, Chalkley RJ, Ball H, Greenbaum D, Bogyo M, Tyson DR, Bradshaw RA, Burlingame AL (2004) Mol Cell Proteomics 3(5): 429-40
    › Primary publication · 14752058 (PubMed)
  13. PC12 cell activation by epidermal growth factor receptor: role of autophosphorylation sites. Tyson DR, Larkin S, Hamai Y, Bradshaw RA (2003) Int J Dev Neurosci 21(2): 63-74
    › Primary publication · 12615082 (PubMed)
  14. Induction of transcriptional activity of the cyclic adenosine monophosphate response element binding protein by parathyroid hormone and epidermal growth factor in osteoblastic cells. Swarthout JT, Tyson DR, Jefcoat SC, Partridge NC, Efcoat SC (2002) J Bone Miner Res 17(8): 1401-7
    › Primary publication · 12162494 (PubMed)
  15. PTH induction of transcriptional activity of the cAMP response element-binding protein requires the serine 129 site and glycogen synthase kinase-3 activity, but not casein kinase II sites. Tyson DR, Swarthout JT, Jefcoat SC, Partridge NC (2002) Endocrinology 143(2): 674-82
    › Primary publication · 11796524 (PubMed)
  16. Parathyroid hormone regulation of the rat collagenase-3 promoter by protein kinase A-dependent transactivation of core binding factor alpha1. Selvamurugan N, Pulumati MR, Tyson DR, Partridge NC (2000) J Biol Chem 275(7): 5037-42
    › Primary publication · 10671545 (PubMed)
  17. Increased osteoblastic c-fos expression by parathyroid hormone requires protein kinase A phosphorylation of the cyclic adenosine 3',5'-monophosphate response element-binding protein at serine 133. Tyson DR, Swarthout JT, Partridge NC (1999) Endocrinology 140(3): 1255-61
    › Primary publication · 10067851 (PubMed)
  18. Parathyroid hormone versus phorbol ester stimulation of activator protein-1 gene family members in rat osteosarcoma cells. Koe RC, Clohisy JC, Tyson DR, Pulumati MR, Cook TF, Partridge NC (1997) Calcif Tissue Int 61(1): 52-8
    › Primary publication · 9192514 (PubMed)

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Keywords & MeSH Terms

MeSH terms are retrieved from PubMed records. Learn more.

Key: MeSH Term Keyword

Aged Amino Acid Sequence Calcium-Calmodulin-Dependent Protein Kinases Carcinogens Cell Proliferation Chloramphenicol O-Acetyltransferase Core Binding Factor Alpha 1 Subunit Cyclic AMP-Dependent Protein Kinases Dose-Response Relationship, Drug Enzyme Inhibitors Genistein Image Processing, Computer-Assisted Ligands Lithium Chloride Microscopy, Fluorescence Models, Biological Molecular Sequence Data Neoplasm Invasiveness Osteoblasts Parathyroid Hormone Peptide Fragments Peptides Phosphoric Monoester Hydrolases Phosphotransferases Platelet-Derived Growth Factor Prostate Proteomics Recurrence Threonine Transfection