jeff franklin
Faculty Member
Last active: 3/28/2016

Profile

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Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF-α-induced apoptosis in vivo. Simmons AJ, Banerjee A, McKinley ET, Scurrah CR, Herring CA, Gewin LS, Masuzaki R, Karp SJ, Franklin JL, Gerdes MJ, Irish JM, Coffey RJ, Lau KS (2015) Mol Syst Biol 11(10): 835
    › Primary publication · 26519361 (PubMed) · PMC4631206 (PubMed Central)
  2. Potential functional applications of extracellular vesicles: a report by the NIH Common Fund Extracellular RNA Communication Consortium. Quesenberry PJ, Aliotta J, Camussi G, Abdel-Mageed AB, Wen S, Goldberg L, Zhang HG, Tetta C, Franklin J, Coffey RJ, Danielson K, Subramanya V, Ghiran I, Das S, Chen CC, Pusic KM, Pusic AD, Chatterjee D, Kraig RP, Balaj L, Dooner M (2015) J Extracell Vesicles : 27575
    › Primary publication · 26320942 (PubMed) · PMC4553260 (PubMed Central)
  3. Biogenesis, delivery, and function of extracellular RNA. Patton JG, Franklin JL, Weaver AM, Vickers K, Zhang B, Coffey RJ, Ansel KM, Blelloch R, Goga A, Huang B, L'Etoille N, Raffai RL, Lai CP, Krichevsky AM, Mateescu B, Greiner VJ, Hunter C, Voinnet O, McManus MT (2015) J Extracell Vesicles : 27494
    › Primary publication · 26320939 (PubMed) · PMC4553266 (PubMed Central)
  4. KRAS-dependent sorting of miRNA to exosomes. Cha DJ, Franklin JL, Dou Y, Liu Q, Higginbotham JN, Demory Beckler M, Weaver AM, Vickers K, Prasad N, Levy S, Zhang B, Coffey RJ, Patton JG (2015) Elife : e07197
    › Primary publication · 26132860 (PubMed) · PMC4510696 (PubMed Central)
  5. LRIG1 Regulates Ontogeny of Smooth Muscle-Derived Subsets of Interstitial Cells of Cajal in Mice. Kondo J, Powell AE, Wang Y, Musser MA, Southard-Smith EM, Franklin JL, Coffey RJ (2015) Gastroenterology 149(2): 407-19.e8
    › Primary publication · 25921371 (PubMed) · PMC4527342 (PubMed Central)
  6. Loss of Lrig1 leads to expansion of Brunner glands followed by duodenal adenomas with gastric metaplasia. Wang Y, Shi C, Lu Y, Poulin EJ, Franklin JL, Coffey RJ (2015) Am J Pathol 185(4): 1123-34
    › Primary publication · 25794708 (PubMed) · PMC4380843 (PubMed Central)
  7. Using a new Lrig1 reporter mouse to assess differences between two Lrig1 antibodies in the intestine. Poulin EJ, Powell AE, Wang Y, Li Y, Franklin JL, Coffey RJ (2014) Stem Cell Res 13(3 Pt A): 422-30
    › Primary publication · 25460603 (PubMed) · PMC4320017 (PubMed Central)
  8. Deciphering genomic alterations in colorectal cancer through transcriptional subtype-based network analysis. Zhu J, Wang J, Shi Z, Franklin JL, Deane NG, Coffey RJ, Beauchamp RD, Zhang B (2013) PLoS One 8(11): e79282
    › Primary publication · 24260186 (PubMed) · PMC3829853 (PubMed Central)
  9. The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Powell AE, Wang Y, Li Y, Poulin EJ, Means AL, Washington MK, Higginbotham JN, Juchheim A, Prasad N, Levy SE, Guo Y, Shyr Y, Aronow BJ, Haigis KM, Franklin JL, Coffey RJ (2012) Cell 149(1): 146-58
    › Primary publication · 22464327 (PubMed) · PMC3563328 (PubMed Central)
  10. Identification of a novel mono-leucine basolateral sorting motif within the cytoplasmic domain of amphiregulin. Gephart JD, Singh B, Higginbotham JN, Franklin JL, Gonzalez A, Fölsch H, Coffey RJ (2011) Traffic 12(12): 1793-804
    › Primary publication · 21917092 (PubMed) · PMC3886124 (PubMed Central)
  11. Amphiregulin exosomes increase cancer cell invasion. Higginbotham JN, Demory Beckler M, Gephart JD, Franklin JL, Bogatcheva G, Kremers GJ, Piston DW, Ayers GD, McConnell RE, Tyska MJ, Coffey RJ (2011) Curr Biol 21(9): 779-86
    › Primary publication · 21514161 (PubMed) · PMC3417320 (PubMed Central)
  12. Naked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-catenin. Van Raay TJ, Fortino NJ, Miller BW, Ma H, Lau G, Li C, Franklin JL, Attisano L, Solnica-Krezel L, Coffey RJ (2011) PLoS One 6(4): e18650
    › Primary publication · 21490931 (PubMed) · PMC3072412 (PubMed Central)
  13. A unified mixed effects model for gene set analysis of time course microarray experiments. Wang L, Chen X, Wolfinger RD, Franklin JL, Coffey RJ, Zhang B (2009) Stat Appl Genet Mol Biol : Article 47
    › Primary publication · 19954419 (PubMed) · PMC2861317 (PubMed Central)
  14. Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis. Cao Z, Li C, Higginbotham JN, Franklin JL, Tabb DL, Graves-Deal R, Hill S, Cheek K, Jerome WG, Lapierre LA, Goldenring JR, Ham AJ, Coffey RJ (2008) Mol Cell Proteomics 7(9): 1651-67
    › Primary publication · 18504258 (PubMed) · PMC2528074 (PubMed Central)
  15. Conditionally immortalized colonic epithelial cell line from a Ptk6 null mouse that polarizes and differentiates in vitro. Whitehead RH, Robinson PS, Williams JA, Bie W, Tyner AL, Franklin JL (2008) J Gastroenterol Hepatol 23(7 Pt 1): 1119-24
    › Primary publication · 18205771 (PubMed) · PMC3005200 (PubMed Central)
  16. Lrp6 is required for convergent extension during Xenopus gastrulation. Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E (2007) Development 134(22): 4095-106
    › Primary publication · 17965054 (PubMed) · PMC4428168 (PubMed Central)
  17. Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium. Keller JW, Franklin JL, Graves-Deal R, Friedman DB, Whitwell CW, Coffey RJ (2007) J Cell Physiol 210(3): 740-9
    › Primary publication · 17133351 (PubMed)
  18. Oncogenic K-RAS subverts the antiapoptotic role of N-RAS and alters modulation of the N-RAS:gelsolin complex. Keller JW, Haigis KM, Franklin JL, Whitehead RH, Jacks T, Coffey RJ (2007) Oncogene 26(21): 3051-9
    › Primary publication · 17130841 (PubMed)
  19. Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine. Amann JM, Chyla BJ, Ellis TC, Martinez A, Moore AC, Franklin JL, McGhee L, Meyers S, Ohm JE, Luce KS, Ouelette AJ, Washington MK, Thompson MA, King D, Gautam S, Coffey RJ, Whitehead RH, Hiebert SW (2005) Mol Cell Biol 25(21): 9576-85
    › Primary publication · 16227606 (PubMed) · PMC1265807 (PubMed Central)
  20. Differential effects of amphiregulin and TGF-alpha on the morphology of MDCK cells. Chung E, Graves-Deal R, Franklin JL, Coffey RJ (2005) Exp Cell Res 309(1): 149-60
    › Primary publication · 15979068 (PubMed)
  21. Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein. Franklin JL, Yoshiura K, Dempsey PJ, Bogatcheva G, Jeyakumar L, Meise KS, Pearsall RS, Threadgill D, Coffey RJ (2005) Exp Cell Res 303(2): 457-70
    › Primary publication · 15652357 (PubMed)
  22. Gene expression profile analysis of mouse colon embryonic development. Park YK, Franklin JL, Settle SH, Levy SE, Chung E, Jeyakumar LH, Shyr Y, Washington MK, Whitehead RH, Aronow BJ, Coffey RJ (2005) Genesis 41(1): 1-12
    › Primary publication · 15645444 (PubMed)
  23. Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells. Li C, Franklin JL, Graves-Deal R, Jerome WG, Cao Z, Coffey RJ (2004) Proc Natl Acad Sci U S A 101(15): 5571-6
    › Primary publication · 15064403 (PubMed) · PMC397424 (PubMed Central)
  24. Autonomous and non-autonomous regulation of mammalian neurite development by Notch1 and Delta1. Franklin JL, Berechid BE, Cutting FB, Presente A, Chambers CB, Foltz DR, Ferreira A, Nye JS (1999) Curr Biol 9(24): 1448-57
    › Primary publication · 10607588 (PubMed)
  25. The largest (70 kDa) product of the bacteriophage T4 DNA terminase gene 17 binds to single-stranded DNA segments and digests them towards junctions with double-stranded DNA. Franklin JL, Haseltine D, Davenport L, Mosig G (1998) J Mol Biol 277(3): 541-57
    › Primary publication · 9533879 (PubMed)
  26. Expression of the bacteriophage T4 DNA terminase genes 16 and 17 yields multiple proteins. Franklin JL, Mosig G (1996) Gene 177(1-2): 179-89
    › Primary publication · 8921865 (PubMed)
  27. Ventral neural cadherin, a novel cadherin expressed in a subset of neural tissues in the zebrafish embryo. Franklin JI, Sargent TD (1996) Dev Dyn 206(2): 121-30
    › Primary publication · 8725279 (PubMed)
  28. Functional relationships and structural determinants of two bacteriophage T4 lysozymes: a soluble (gene e) and a baseplate-associated (gene 5) protein. Mosig G, Lin GW, Franklin J, Fan WH (1989) New Biol 1(2): 171-9
    › Primary publication · 2488704 (PubMed)
  29. Bacteriophage T4 DNA packaging genes 16 and 17. Powell D, Franklin J, Arisaka F, Mosig G (1990) Nucleic Acids Res 18(13): 4005
    › Primary publication · 2374730 (PubMed) · PMC331121 (PubMed Central)