Danielle Dean, Ph.D.

Official Affiliation: Vanderbilt Diabetes Center

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Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion. Bozadjieva N, Blandino-Rosano M, Chase J, Dai XQ, Cummings K, Gimeno J, Dean D, Powers AC, Gittes GK, Rüegg MA, Hall MN, MacDonald PE, Bernal-Mizrachi E (2017) J Clin Invest 127(12): 4379-4393
    › Primary publication · 29106387 (PubMed) · PMC5707167 (PubMed Central)
  2. Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation. Dean ED, Li M, Prasad N, Wisniewski SN, Von Deylen A, Spaeth J, Maddison L, Botros A, Sedgeman LR, Bozadjieva N, Ilkayeva O, Coldren A, Poffenberger G, Shostak A, Semich MC, Aamodt KI, Phillips N, Yan H, Bernal-Mizrachi E, Corbin JD, Vickers KC, Levy SE, Dai C, Newgard C, Gu W, Stein R, Chen W, Powers AC (2017) Cell Metab 25(6): 1362-1373.e5
    › Primary publication · 28591638 (PubMed) · PMC5572896 (PubMed Central)
  3. Glucagon antagonism in islet cell proliferation. Dean ED, Unger RH, Holland WL (2017) Proc Natl Acad Sci U S A 114(12): 3006-3008
    › Primary publication · 28283660 (PubMed) · PMC5373377 (PubMed Central)
  4. Glucagon receptor inactivation leads to α-cell hyperplasia in zebrafish. Li M, Dean ED, Zhao L, Nicholson WE, Powers AC, Chen W (2015) J Endocrinol 227(2): 93-103
    › Primary publication · 26446275 (PubMed) · PMC4598637 (PubMed Central)
  5. Liver-specific disruption of the murine glucagon receptor produces α-cell hyperplasia: evidence for a circulating α-cell growth factor. Longuet C, Robledo AM, Dean ED, Dai C, Ali S, McGuinness I, de Chavez V, Vuguin PM, Charron MJ, Powers AC, Drucker DJ (2013) Diabetes 62(4): 1196-205
    › Primary publication · 23160527 (PubMed) · PMC3609565 (PubMed Central)
  6. 25-Hydroxyvitamin D depletion does not exacerbate MPTP-induced dopamine neuron damage in mice. Dean ED, Mexas LM, Cápiro NL, McKeon JE, DeLong MR, Pennell KD, Doorn JA, Tangpricha V, Miller GW, Evatt ML (2012) PLoS One 7(7): e39227
    › Primary publication · 22768297 (PubMed) · PMC3388077 (PubMed Central)
  7. Developmental heptachlor exposure increases susceptibility of dopamine neurons to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)in a gender-specific manner. Richardson JR, Caudle WM, Wang MZ, Dean ED, Pennell KD, Miller GW (2008) Neurotoxicology 29(5): 855-63
    › Primary publication · 18577399 (PubMed) · PMC2574680 (PubMed Central)
  8. Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease. Richardson JR, Caudle WM, Wang M, Dean ED, Pennell KD, Miller GW (2006) FASEB J 20(10): 1695-7
    › Primary publication · 16809432 (PubMed)

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615-936-16172 (p)
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Keywords & MeSH Terms

MeSH terms are retrieved from PubMed records. Learn more.

Key: MeSH Term Keyword

alpha cell hyperplasia Alpha cells amino acid metabolism amino acids Amino Acid Transport Systems Amino Acid Transport Systems, Neutral Animals, Genetically Modified Animals, Newborn Caffeine Cell Proliferation Corpus Striatum Cytochrome P-450 Enzyme System Dieldrin Dopamine Dopamine Plasma Membrane Transport Proteins Drosophila melanogaster Gene Expression Genes, Reporter Glucagon Glucagon-Secreting Cells Glucagonoma glucagon secretion Glucose Glutaminase Glutamine Hepatocytes hyperaminoacidemia Hyperargininemia hyperglucagonmia hyperglutaminemia Insulin Resistance Islet biology Liver Male Mechanistic Target of Rapamycin Complex 1 Mice, Inbred C57BL Parkinson Disease, Secondary Pesticides Proliferation Receptors, Glucagon Regulatory-Associated Protein of mTOR Sex Factors Substantia Nigra Type 1 Diabetes type 2 diabetes Tyrosine 3-Monooxygenase Zebrafish