Christopher Coldren
Last active: 10/17/2012


Over the past decade I have conducted translational genomics research. While the technology platforms and research questions I work with have evolved, I have remained driven by a desire to use and develop methods that connect measurements with biological inference in translational research. As Operations Director of the Vanderbilt Genome Sciences Resource I look forward to the opportunity to continue using and developing methods in collaboration with a broad spectrum of Vanderbilt research groups.


The following timeline graph is generated from all co-authored publications.

  1. Progressive endobronchial premalignancy: marked by original CIN. Coldren CD, Miller YE (2011) Am J Respir Crit Care Med 184(8): 869-70
    › Primary publication · 22003147 (PubMed) · PMC3208658 (PubMed Central)
  2. Bacteria-specific neutrophil dysfunction associated with interferon-stimulated gene expression in the acute respiratory distress syndrome. Malcolm KC, Kret JE, Young RL, Poch KR, Caceres SM, Douglas IS, Coldren CD, Burnham EL, Moss M, Nick JA (2011) PLoS One 6(7): e21958
    › Primary publication · 21755013 (PubMed) · PMC3130788 (PubMed Central)
  3. ZEB1-responsive genes in non-small cell lung cancer. Gemmill RM, Roche J, Potiron VA, Nasarre P, Mitas M, Coldren CD, Helfrich BA, Garrett-Mayer E, Bunn PA, Drabkin HA (2011) Cancer Lett 300(1): 66-78
    › Primary publication · 20980099 (PubMed) · PMC3337721 (PubMed Central)
  4. Altered immune phenotype in peripheral blood cells of patients with scleroderma-associated pulmonary hypertension. Risbano MG, Meadows CA, Coldren CD, Jenkins TJ, Edwards MG, Collier D, Huber W, Mack DG, Fontenot AP, Geraci MW, Bull TM (2010) Clin Transl Sci 3(5): 210-8
    › Primary publication · 20973920 (PubMed) · PMC2966033 (PubMed Central)
  5. Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension. Aldred MA, Comhair SA, Varella-Garcia M, Asosingh K, Xu W, Noon GP, Thistlethwaite PA, Tuder RM, Erzurum SC, Geraci MW, Coldren CD (2010) Am J Respir Crit Care Med 182(9): 1153-60
    › Primary publication · 20581168 (PubMed) · PMC3001257 (PubMed Central)
  6. Development of an integrated genomic classifier for a novel agent in colorectal cancer: approach to individualized therapy in early development. Pitts TM, Tan AC, Kulikowski GN, Tentler JJ, Brown AM, Flanigan SA, Leong S, Coldren CD, Hirsch FR, Varella-Garcia M, Korch C, Eckhardt SG (2010) Clin Cancer Res 16(12): 3193-204
    › Primary publication · 20530704 (PubMed) · PMC2889230 (PubMed Central)
  7. Preclinical efficacy of a carboxylesterase 2-activated prodrug of doxazolidine. Barthel BL, Zhang Z, Rudnicki DL, Coldren CD, Polinkovsky M, Sun H, Koch GG, Chan DC, Koch TH (2009) J Med Chem 52(23): 7678-88
    › Primary publication · 19634903 (PubMed) · PMC2788667 (PubMed Central)
  8. Randomization in laboratory procedure is key to obtaining reproducible microarray results. Yang H, Harrington CA, Vartanian K, Coldren CD, Hall R, Churchill GA (2008) PLoS One 3(11): e3724
    › Primary publication · 19009020 (PubMed) · PMC2579585 (PubMed Central)
  9. Chromosomal microarray mapping suggests a role for BSX and Neurogranin in neurocognitive and behavioral defects in the 11q terminal deletion disorder (Jacobsen syndrome). Coldren CD, Lai Z, Shragg P, Rossi E, Glidewell SC, Zuffardi O, Mattina T, Ivy DD, Curfs LM, Mattson SN, Riley EP, Treier M, Grossfeld PD (2009) Neurogenetics 10(2): 89-95
    › Primary publication · 18855024 (PubMed) · PMC3050515 (PubMed Central)
  10. Fibroblast growth factor (FGF) and FGF receptor-mediated autocrine signaling in non-small-cell lung cancer cells. Marek L, Ware KE, Fritzsche A, Hercule P, Helton WR, Smith JE, McDermott LA, Coldren CD, Nemenoff RA, Merrick DT, Helfrich BA, Bunn PA, Heasley LE (2009) Mol Pharmacol 75(1): 196-207
    › Primary publication · 18849352 (PubMed) · PMC2669785 (PubMed Central)