Bill Tansey, Ph.D

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Publications

The following timeline graph is generated from all co-authored publications.

1. Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Aho ER, Wang J, Gogliotti RD, Howard GC, Phan J, Acharya P, Macdonald JD, Cheng K, Lorey SL, Lu B, Wenzel S, Foshage AM, Alvarado J, Wang F, Shaw JG, Zhao B, Weissmiller AM, Thomas LR, Vakoc CR, Hall MD, Hiebert SW, Liu Q, Stauffer SR, Fesik SW, Tansey WP (2019) Cell Rep 26(11): 2916-2928.e13
   › Primary publication · 30865883 (PubMed) · PMC6448596 (PubMed Central)
2. Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling. Ng VH, Hang BI, Sawyer LM, Neitzel LR, Crispi EE, Rose KL, Popay TM, Zhong A, Lee LA, Tansey WP, Huppert S, Lee E (2018) J Cell Sci 131(10)
   › Primary publication · 29678905 (PubMed) · PMC6031333 (PubMed Central)
3. Moonlighting with WDR5: A Cellular Multitasker. Guarnaccia AD, Tansey WP (2018) J Clin Med 7(2)
   › Primary publication · 29385767 (PubMed) · PMC5852437 (PubMed Central)
4. BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis. Parang B, Kaz AM, Barrett CW, Short SP, Ning W, Keating CE, Mittal MK, Naik RD, Washington MK, Revetta FL, Smith JJ, Chen X, Wilson KT, Brand T, Bader DM, Tansey WP, Chen R, Brentnall TA, Grady WM, Williams CS (2017) Gut 66(5): 852-862
   › Primary publication · 28389570 (PubMed) · PMC5385850 (PubMed Central)
5. Interaction of Gcn4 with target gene chromatin is modulated by proteasome function. Howard GC, Tansey WP (2016) Mol Biol Cell 27(17): 2735-41
   › Primary publication · 27385344 (PubMed) · PMC5007093 (PubMed Central)
6. Do changes in the c-MYC coding sequence contribute to tumorigenesis? Chakraborty AA, Tansey WP (2015) Mol Cell Oncol 2(2): e965631
   › Primary publication · 27308414 (PubMed) · PMC4904990 (PubMed Central)
7. Antagonistic roles for the ubiquitin ligase Asr1 and the ubiquitin-specific protease Ubp3 in subtelomeric gene silencing. McCann TS, Guo Y, McDonald WH, Tansey WP (2016) Proc Natl Acad Sci U S A 113(5): 1309-14
   › Primary publication · 26787877 (PubMed) · PMC4747757 (PubMed Central)
8. Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif. Thomas LR, Foshage AM, Weissmiller AM, Popay TM, Grieb BC, Qualls SJ, Ng V, Carboneau B, Lorey S, Eischen CM, Tansey WP (2016) Oncogene 35(27): 3613-8
   › Primary publication · 26522729 (PubMed) · PMC4853269 (PubMed Central)
9. The MYC-WDR5 Nexus and Cancer. Thomas LR, Foshage AM, Weissmiller AM, Tansey WP (2015) Cancer Res 75(19): 4012-5
   › Primary publication · 26383167 (PubMed) · PMC4592407 (PubMed Central)
10. Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC. Thomas LR, Wang Q, Grieb BC, Phan J, Foshage AM, Sun Q, Olejniczak ET, Clark T, Dey S, Lorey S, Alicie B, Howard GC, Cawthon B, Ess KC, Eischen CM, Zhao Z, Fesik SW, Tansey WP (2015) Mol Cell 58(3): 440-52
    › Primary publication · 25818646 (PubMed) · PMC4427524 (PubMed Central)
11. Functions of the proteasome on chromatin. McCann TS, Tansey WP (2014) Biomolecules 4(4): 1026-44
    › Primary publication · 25422899 (PubMed) · PMC4279168 (PubMed Central)
12. The ubiquitin-selective chaperone Cdc48/p97 associates with Ubx3 to modulate monoubiquitylation of histone H2B. Bonizec M, Hérissant L, Pokrzywa W, Geng F, Wenzel S, Howard GC, Rodriguez P, Krause S, Tansey WP, Hoppe T, Dargemont C (2014) Nucleic Acids Res 42(17): 10975-86
    › Primary publication · 25183520 (PubMed) · PMC4176170 (PubMed Central)
13. Stable histone adduction by 4-oxo-2-nonenal: a potential link between oxidative stress and epigenetics. Galligan JJ, Rose KL, Beavers WN, Hill S, Tallman KA, Tansey WP, Marnett LJ (2014) J Am Chem Soc 136(34): 11864-6
    › Primary publication · 25099620 (PubMed) · PMC4151707 (PubMed Central)
14. A common functional consequence of tumor-derived mutations within c-MYC. Chakraborty AA, Scuoppo C, Dey S, Thomas LR, Lorey SL, Lowe SW, Tansey WP (2015) Oncogene 34(18): 2406-9
    › Primary publication · 24998853 (PubMed) · PMC4286529 (PubMed Central)
15. Detection of ubiquitylated proteins in mammalian cells. Tansey WP (2006) CSH Protoc 2006(6)
    › Primary publication · 22485991 (PubMed)
16. Detection of ubiquitylated proteins in yeast. Tansey WP (2006) CSH Protoc 2006(7)
    › Primary publication · 22484671 (PubMed)
17. Freeze-thaw lysis for extraction of proteins from Mammalian cells. Tansey WP (2006) CSH Protoc 2006(7)
    › Primary publication · 22484670 (PubMed)
18. 6-azauracil sensitivity assay for yeast. Tansey WP (2006) CSH Protoc 2006(7)
    › Primary publication · 22484669 (PubMed)
19. Similar temporal and spatial recruitment of native 19S and 20S proteasome subunits to transcriptionally active chromatin. Geng F, Tansey WP (2012) Proc Natl Acad Sci U S A 109(16): 6060-5
    › Primary publication · 22474342 (PubMed) · PMC3341028 (PubMed Central)
20. Ubiquitin and proteasomes in transcription. Geng F, Wenzel S, Tansey WP (2012) Annu Rev Biochem : 177-201
    › Primary publication · 22404630 (PubMed) · PMC3637986 (PubMed Central)
21. Letter to the editor. Chemical-genetic strategy for inhibiting proteasome function in Saccharomyces cerevisiae. Howard GC, Collins GA, Tansey WP (2012) Yeast 29(2): 93-4
    › Primary publication · 22162073 (PubMed) · PMC3657583 (PubMed Central)
22. Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat. Leung A, Cajigas I, Jia P, Ezhkova E, Brickner JH, Zhao Z, Geng F, Tansey WP (2011) Mol Biol Cell 22(15): 2741-53
    › Primary publication · 21680712 (PubMed) · PMC3145549 (PubMed Central)
23. Denaturing protein immunoprecipitation from yeast. Tansey WP (2007) CSH Protoc : pdb.prot4643
    › Primary publication · 21356925 (PubMed)
24. Yeast Chromatin Immunoprecipitation (ChIP) Assay. Tansey WP (2007) CSH Protoc : pdb.prot4642
    › Primary publication · 21356924 (PubMed)
25. Pulse-chase assay for measuring protein stability in yeast. Tansey WP (2007) CSH Protoc : pdb.prot4641
    › Primary publication · 21356923 (PubMed)
26. Nondenaturing protein immunoprecipitation from Mammalian cells. Tansey WP (2007) CSH Protoc : pdb.prot4620
    › Primary publication · 21356922 (PubMed)
27. Denaturing protein immunoprecipitation from Mammalian cells. Tansey WP (2007) CSH Protoc : pdb.prot4619
    › Primary publication · 21356921 (PubMed)
28. Combined chemical and genetic approach to inhibit proteolysis by the proteasome. Collins GA, Gomez TA, Deshaies RJ, Tansey WP (2010) Yeast 27(11): 965-74
    › Primary publication · 20625982 (PubMed) · PMC3566228 (PubMed Central)
29. Proteolytic instability and the action of nonclassical transcriptional activators. Wang X, Muratani M, Tansey WP, Ptashne M (2010) Curr Biol 20(9): 868-71
    › Primary publication · 20417106 (PubMed) · PMC3033761 (PubMed Central)
30. Gal4 turnover and transcription activation. Collins GA, Lipford JR, Deshaies RJ, Tansey WP (2009) Nature 461(7265): E7; discussion E8
    › Primary publication · 19812621 (PubMed) · PMC3072683 (PubMed Central)
31. Inference of cell cycle-dependent proteolysis by laser scanning cytometry. Chakraborty AA, Tansey WP (2009) Exp Cell Res 315(10): 1772-8
    › Primary publication · 19331831 (PubMed) · PMC2680938 (PubMed Central)
32. Damage control: DNA repair, transcription, and the ubiquitin-proteasome system. Daulny A, Tansey WP (2009) DNA Repair (Amst) 8(4): 444-8
    › Primary publication · 19272841 (PubMed)
33. Transcriptional control and the ubiquitin-proteasome system. Leung A, Geng F, Daulny A, Collins G, Guzzardo P, Tansey WP (2008) Ernst Schering Found Symp Proc (1): 75-97
    › Primary publication · 19198065 (PubMed)
34. Adenoviral E1A function through Myc. Chakraborty AA, Tansey WP (2009) Cancer Res 69(1): 6-9
    › Primary publication · 19117980 (PubMed)
35. Modulation of RNA polymerase II subunit composition by ubiquitylation. Daulny A, Geng F, Muratani M, Geisinger JM, Salghetti SE, Tansey WP (2008) Proc Natl Acad Sci U S A 105(50): 19649-54
    › Primary publication · 19064926 (PubMed) · PMC2604917 (PubMed Central)
36. Polyubiquitylation of histone H2B. Geng F, Tansey WP (2008) Mol Biol Cell 19(9): 3616-24
    › Primary publication · 18562693 (PubMed) · PMC2526708 (PubMed Central)
37. Myc-mediated transcriptional repression by recruitment of histone deacetylase. Kurland JF, Tansey WP (2008) Cancer Res 68(10): 3624-9
    › Primary publication · 18483244 (PubMed)
38. Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc. Tworkowski KA, Chakraborty AA, Samuelson AV, Seger YR, Narita M, Hannon GJ, Lowe SW, Tansey WP (2008) Proc Natl Acad Sci U S A 105(16): 6103-8
    › Primary publication · 18413597 (PubMed) · PMC2329713 (PubMed Central)
39. SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae. Pal B, Chan NC, Helfenbaum L, Tan K, Tansey WP, Gething MJ (2007) Mol Biol Cell 18(2): 426-40
    › Primary publication · 17108329 (PubMed) · PMC1783797 (PubMed Central)
40. The proteasome: a utility tool for transcription? Collins GA, Tansey WP (2006) Curr Opin Genet Dev 16(2): 197-202
    › Primary publication · 16503126 (PubMed)
41. The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators. Lee D, Ezhkova E, Li B, Pattenden SG, Tansey WP, Workman JL (2005) Cell 123(3): 423-36
    › Primary publication · 16269334 (PubMed)
42. Chromatin immunoprecipitation to study protein-DNA interactions in budding yeast. Ezhkova E, Tansey WP (2006) Methods Mol Biol : 225-44
    › Primary publication · 16118437 (PubMed)
43. Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants. Hemann MT, Bric A, Teruya-Feldstein J, Herbst A, Nilsson JA, Cordon-Cardo C, Cleveland JL, Tansey WP, Lowe SW (2005) Nature 436(7052): 807-11
    › Primary publication · 16094360 (PubMed) · PMC4599579 (PubMed Central)
44. The F box protein Dsg1/Mdm30 is a transcriptional coactivator that stimulates Gal4 turnover and cotranscriptional mRNA processing. Muratani M, Kung C, Shokat KM, Tansey WP (2005) Cell 120(6): 887-99
    › Primary publication · 15797387 (PubMed)
45. A conserved element in Myc that negatively regulates its proapoptotic activity. Herbst A, Hemann MT, Tworkowski KA, Salghetti SE, Lowe SW, Tansey WP (2005) EMBO Rep 6(2): 177-83
    › Primary publication · 15678160 (PubMed) · PMC1299243 (PubMed Central)
46. Death, destruction, and the proteasome. Tansey WP (2004) N Engl J Med 351(4): 393-4
    › Primary publication · 15269322 (PubMed)
47. Crashing waves of destruction: the cell cycle and APC(Cdh1) regulation of SCF(Skp2). Kurland JF, Tansey WP (2004) Cancer Cell 5(4): 305-6
    › Primary publication · 15093536 (PubMed)
48. A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment. Tubon TC, Tansey WP, Herr W (2004) Mol Cell Biol 24(7): 2863-74
    › Primary publication · 15024075 (PubMed) · PMC371104 (PubMed Central)
49. Multiple cell-type-specific elements regulate Myc protein stability. Herbst A, Salghetti SE, Kim SY, Tansey WP (2004) Oncogene 23(21): 3863-71
    › Primary publication · 15021906 (PubMed)
50. From silencing to gene expression: real-time analysis in single cells. Janicki SM, Tsukamoto T, Salghetti SE, Tansey WP, Sachidanandam R, Prasanth KV, Ried T, Shav-Tal Y, Bertrand E, Singer RH, Spector DL (2004) Cell 116(5): 683-98
    › Primary publication · 15006351 (PubMed) · PMC4942132 (PubMed Central)
51. Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3. Ezhkova E, Tansey WP (2004) Mol Cell 13(3): 435-42
    › Primary publication · 14967150 (PubMed)
52. Skp2 regulates Myc protein stability and activity. Kim SY, Herbst A, Tworkowski KA, Salghetti SE, Tansey WP (2003) Mol Cell 11(5): 1177-88
    › Primary publication · 12769843 (PubMed)
53. How the ubiquitin-proteasome system controls transcription. Muratani M, Tansey WP (2003) Nat Rev Mol Cell Biol 4(3): 192-201
    › Primary publication · 12612638 (PubMed)
54. Stable and unstable pools of Myc protein exist in human cells. Tworkowski KA, Salghetti SE, Tansey WP (2002) Oncogene 21(55): 8515-20
    › Primary publication · 12466972 (PubMed)
55. Regulation of c-myc stability by selective stress conditions and by MEKK1 requires aa 127-189 of c-myc. Alarcon-Vargas D, Tansey WP, Ronai Z (2002) Oncogene 21(28): 4384-91
    › Primary publication · 12080469 (PubMed)
56. Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. Méndez J, Zou-Yang XH, Kim SY, Hidaka M, Tansey WP, Stillman B (2002) Mol Cell 9(3): 481-91
    › Primary publication · 11931757 (PubMed)
57. Old dogs and new tricks: meeting on mechanisms of eukaryotic transcription. Ejkova E, Tansey WP (2002) EMBO Rep 3(3): 219-23
    › Primary publication · 11882540 (PubMed) · PMC1084018 (PubMed Central)
58. Regulation of transcriptional activation domain function by ubiquitin. Salghetti SE, Caudy AA, Chenoweth JG, Tansey WP (2001) Science 293(5535): 1651-3
    › Primary publication · 11463878 (PubMed)
59. HAM: a new epitope-tag for in vivo protein labeling. Herbst A, Tansey WP (2000) Mol Biol Rep 27(4): 203-8
    › Primary publication · 11455955 (PubMed)
60. Transcriptional activation: risky business. Tansey WP (2001) Genes Dev 15(9): 1045-50
    › Primary publication · 11331599 (PubMed)
61. Transcriptional regulation: RUPture in the ER. Tansey WP (2000) Nat Cell Biol 2(10): E175-7
    › Primary publication · 11025674 (PubMed)
62. Functional overlap of sequences that activate transcription and signal ubiquitin-mediated proteolysis. Salghetti SE, Muratani M, Wijnen H, Futcher B, Tansey WP (2000) Proc Natl Acad Sci U S A 97(7): 3118-23
    › Primary publication · 10706616 (PubMed) · PMC16202 (PubMed Central)
63. How cells use proteolysis to control their growth. Tansey WP (1999) Mol Med 5(12): 773-82
    › Primary publication · 10666476 (PubMed) · PMC2230494 (PubMed Central)
64. Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc. Salghetti SE, Kim SY, Tansey WP (1999) EMBO J 18(3): 717-26
    › Primary publication · 9927431 (PubMed) · PMC1171164 (PubMed Central)
65. TAFs: guilt by association? Tansey WP, Herr W (1997) Cell 88(6): 729-32
    › Primary publication · 9118213 (PubMed)
66. Selective use of TBP and TFIIB revealed by a TATA-TBP-TFIIB array with altered specificity. Tansey WP, Herr W (1997) Science 275(5301): 829-31
    › Primary publication · 9012349 (PubMed)
67. Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly. Pendergrast PS, Morrison D, Tansey WP, Hernandez N (1996) J Virol 70(8): 5025-34
    › Primary publication · 8764009 (PubMed) · PMC190456 (PubMed Central)
68. Distance-dependent interactions between basal, cyclic AMP, and thyroid hormone response elements in the rat growth hormone promoter. Tansey WP, Schaufele F, Heslewood M, Handford C, Reudelhuber TL, Catanzaro DF (1993) J Biol Chem 268(20): 14906-11
    › Primary publication · 8392063 (PubMed)
69. Renin gene promoter activity in GC cells is regulated by cAMP and thyroid hormone through Pit-1-dependent mechanisms. Gilbert MT, Sun J, Yan Y, Oddoux C, Lazarus A, Tansey WP, Lavin TN, Catanzaro DF (1994) J Biol Chem 269(45): 28049-54
    › Primary publication · 7961740 (PubMed)
70. Multiple regions of TBP participate in the response to transcriptional activators in vivo. Tansey WP, Ruppert S, Tjian R, Herr W (1994) Genes Dev 8(22): 2756-69
    › Primary publication · 7958931 (PubMed)
71. The ability to associate with activation domains in vitro is not required for the TATA box-binding protein to support activated transcription in vivo. Tansey WP, Herr W (1995) Proc Natl Acad Sci U S A 92(23): 10550-4
    › Primary publication · 7479838 (PubMed) · PMC40649 (PubMed Central)
72. Sp1 and thyroid hormone receptor differentially activate expression of human growth hormone and chorionic somatomammotropin genes. Tansey WP, Catanzaro DF (1991) J Biol Chem 266(15): 9805-13
    › Primary publication · 2033067 (PubMed)
73. Transcriptional and posttranscriptional activation of urokinase plasminogen activator gene expression in metastatic tumor cells. Henderson BR, Tansey WP, Phillips SM, Ramshaw IA, Kefford RF (1992) Cancer Res 52(9): 2489-96
    › Primary publication · 1568219 (PubMed)

Keywords & MeSH Terms

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