KIM-1-mediated phagocytosis reduces acute injury to the kidney. Yang L, Brooks CR, Xiao S, Sabbisetti V, Yeung MY, Hsiao LL, Ichimura T, Kuchroo V, Bonventre JV (2015) J Clin Invest 125: 1620-36 KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation. Brooks CR, Yeung MY, Brooks YS, Chen H, Ichimura T, Henderson JM, Bonventre JV (2015) EMBO J 34: 2441-64 Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK (2012) Proc Natl Acad Sci U S A 109: 12105-10 Furosemide Stress Test and Biomarkers for the Prediction of AKI Severity. Koyner JL, Davison DL, Brasha-Mitchell E, Chalikonda DM, Arthur JM, Shaw AD, Tumlin JA, Trevino SA, Bennett MR, Kimmel PL, Seneff MG, Chawla LS (2015) J Am Soc Nephrol 26: 2023-31 Evaluation of 32 urine biomarkers to predict the progression of acute kidney injury after cardiac surgery. Arthur JM, Hill EG, Alge JL, Lewis EC, Neely BA, Janech MG, Tumlin JA, Chawla LS, Shaw AD, SAKInet Investigators (2014) Kidney Int 85: 431-8 Kim-1/Tim-1 and immune cells: shifting sands. Ichimura T, Brooks CR, Bonventre JV (2012) Kidney Int 81: 809-11 Urinary L-FABP predicts poor outcomes in critically ill patients with early acute kidney injury. Parr SK, Clark AJ, Bian A, Shintani AK, Wickersham NE, Ware LB, Ikizler TA, Siew ED (2015) Kidney Int 87: 640-8 KIM-1/TIM-1 in proximal tubular cell immune response. Brooks CR, Bonventre JV (2015) Oncotarget 6: 44059-60 TIM-1 signaling is required for maintenance and induction of regulatory B cells. Yeung MY, Ding Q, Brooks CR, Xiao S, Workman CJ, Vignali DA, Ueno T, Padera RF, Kuchroo VK, Najafian N, Rothstein DM (2015) Am J Transplant 15: 942-53 Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation. Xiao S, Brooks CR, Sobel RA, Kuchroo VK (2015) J Immunol 194: 1602-8 CRISPR/Cas9 engineering of a KIM-1 reporter human proximal tubule cell line. Veach RA, Wilson MH (2018) PLoS One 13: e0204487 Update on acute kidney injury after cardiac surgery. Shaw A (2012) J Thorac Cardiovasc Surg 143: 676-81
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