Multiplexed transposon-mediated stable gene transfer in human cells. Kahlig KM, Saridey SK, Kaja A, Daniels MA, George AL, Wilson MH (2010) Proc Natl Acad Sci U S A 107: 1343-8 Strain- and age-dependent hippocampal neuron sodium currents correlate with epilepsy severity in Dravet syndrome mice. Mistry AM, Thompson CH, Miller AR, Vanoye CG, George AL, Kearney JA (2014) Neurobiol Dis 65: 1-11 Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus. Hawkins NA, Martin MS, Frankel WN, Kearney JA, Escayg A (2011) Neurobiol Dis 41: 655-60 Ranolazine reduces neuronal excitability by interacting with inactivated states of brain sodium channels. Kahlig KM, Hirakawa R, Liu L, George AL, Belardinelli L, Rajamani S (2014) Mol Pharmacol 85: 162-74 Early treatment suppresses the development of spike-wave epilepsy in a rat model. Blumenfeld H, Klein JP, Schridde U, Vestal M, Rice T, Khera DS, Bashyal C, Giblin K, Paul-Laughinghouse C, Wang F, Phadke A, Mission J, Agarwal RK, Englot DJ, Motelow J, Nersesyan H, Waxman SG, Levin AR (2008) Epilepsia 49: 400-9 Unexpected Efficacy of a Novel Sodium Channel Modulator in Dravet Syndrome. Anderson LL, Hawkins NA, Thompson CH, Kearney JA, George AL (2017) Sci Rep 7: 1682 The synthetic neuroactive steroid SGE-516 reduces seizure burden and improves survival in a Dravet syndrome mouse model. Hawkins NA, Lewis M, Hammond RS, Doherty JJ, Kearney JA (2017) Sci Rep 7: 15327
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