Transmission of Mycobacterium tuberculosis from health care workers. Sterling TR, Haas DW (2006) N Engl J Med 355: 118-21 The case against anergy testing as a routine adjunct to tuberculin skin testing. Slovis BS, Plitman JD, Haas DW (2000) JAMA 283: 2003-7 Chemokine receptor 2 serves an early and essential role in resistance to Mycobacterium tuberculosis. Peters W, Scott HM, Chambers HF, Flynn JL, Charo IF, Ernst JD (2001) Proc Natl Acad Sci U S A 98: 7958-63 Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors. Podust LM, Poulos TL, Waterman MR (2001) Proc Natl Acad Sci U S A 98: 3068-73 Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis. Bellamine A, Mangla AT, Nes WD, Waterman MR (1999) Proc Natl Acad Sci U S A 96: 8937-42 Mycobacterium tuberculosis evades host immunity by recruiting mesenchymal stem cells. Raghuvanshi S, Sharma P, Singh S, Van Kaer L, Das G (2010) Proc Natl Acad Sci U S A 107: 21653-8 Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children. Lewinsohn DM, Leonard MK, LoBue PA, Cohn DL, Daley CL, Desmond E, Keane J, Lewinsohn DA, Loeffler AM, Mazurek GH, O'Brien RJ, Pai M, Richeldi L, Salfinger M, Shinnick TM, Sterling TR, Warshauer DM, Woods GL (2017) Clin Infect Dis 64: 111-115 Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children. Lewinsohn DM, Leonard MK, LoBue PA, Cohn DL, Daley CL, Desmond E, Keane J, Lewinsohn DA, Loeffler AM, Mazurek GH, O'Brien RJ, Pai M, Richeldi L, Salfinger M, Shinnick TM, Sterling TR, Warshauer DM, Woods GL (2017) Clin Infect Dis 64: e1-e33 Chemokines and tuberculosis. Algood HM, Chan J, Flynn JL (2003) Cytokine Growth Factor Rev 14: 467-77 Molecular analysis of sarcoidosis tissues for mycobacterium species DNA. Drake WP, Pei Z, Pride DT, Collins RD, Cover TL, Blaser MJ (2002) Emerg Infect Dis 8: 1334-41 Proinflammatory cytokine and human immunodeficiency virus RNA levels during early Mycobacterium avium complex bacteremia in advanced AIDS. Haas DW, Lederman MM, Clough LA, Wallis RS, Chernoff D, Crampton SL (1998) J Infect Dis 177: 1746-9 An important role of prostanoid receptor EP2 in host resistance to Mycobacterium tuberculosis infection in mice. Kaul V, Bhattacharya D, Singh Y, Van Kaer L, Peters-Golden M, Bishai WR, Das G (2012) J Infect Dis 206: 1816-25 Hypersensitivity pneumonitis associated with Mycobacterium avium complex and hot tub use. Rickman OB, Ryu JH, Fidler ME, Kalra S (2002) Mayo Clin Proc 77: 1233-7 Current and future applications of polymerase chain reaction for Mycobacterium tuberculosis. Haas DW (1996) Mayo Clin Proc 71: 311-13 CCR5-deficient mice control Mycobacterium tuberculosis infection despite increased pulmonary lymphocytic infiltration. Algood HM, Flynn JL (2004) J Immunol 173: 3287-96 A systematic review of gyrase mutations associated with fluoroquinolone-resistant Mycobacterium tuberculosis and a proposed gyrase numbering system. Maruri F, Sterling TR, Kaiga AW, Blackman A, van der Heijden YF, Mayer C, Cambau E, Aubry A (2012) J Antimicrob Chemother 67: 819-31 Nontuberculous mycobacterial peritonitis associated with continuous ambulatory peritoneal dialysis. Pulliam JP, Vernon DD, Alexander SR, Hartstein AI, Golper TA (1983) Am J Kidney Dis 2: 610-4 Mycobacterium tuberculosis controls microRNA-99b (miR-99b) expression in infected murine dendritic cells to modulate host immunity. Singh Y, Kaul V, Mehra A, Chatterjee S, Tousif S, Dwivedi VP, Suar M, Van Kaer L, Bishai WR, Das G (2013) J Biol Chem 288: 5056-61 Folding requirements are different between sterol 14alpha-demethylase (CYP51) from Mycobacterium tuberculosis and human or fungal orthologs. Lepesheva GI, Podust LM, Bellamine A, Waterman MR (2001) J Biol Chem 276: 28413-20 Mycobacterium tuberculosis directs T helper 2 cell differentiation by inducing interleukin-1β production in dendritic cells. Dwivedi VP, Bhattacharya D, Chatterjee S, Prasad DV, Chattopadhyay D, Van Kaer L, Bishai WR, Das G (2012) J Biol Chem 287: 33656-63 Mycobacterium tuberculosis TlyA Protein Negatively Regulates T Helper (Th) 1 and Th17 Differentiation and Promotes Tuberculosis Pathogenesis. Rahman MA, Sobia P, Dwivedi VP, Bhawsar A, Singh DK, Sharma P, Moodley P, Van Kaer L, Bishai WR, Das G (2015) J Biol Chem 290: 14407-17 Small molecule-directed immunotherapy against recurrent infection by Mycobacterium tuberculosis. Bhattacharya D, Dwivedi VP, Maiga M, Maiga M, Van Kaer L, Bishai WR, Das G (2014) J Biol Chem 289: 16508-15 Isoniazid induces apoptosis of activated CD4+ T cells: implications for post-therapy tuberculosis reactivation and reinfection. Tousif S, Singh DK, Ahmad S, Moodley P, Bhattacharyya M, Van Kaer L, Das G (2014) J Biol Chem 289: 30190-5 Simultaneous inhibition of T helper 2 and T regulatory cell differentiation by small molecules enhances Bacillus Calmette-Guerin vaccine efficacy against tuberculosis. Bhattacharya D, Dwivedi VP, Kumar S, Reddy MC, Van Kaer L, Moodley P, Das G (2014) J Biol Chem 289: 33404-11 Structural diversities of active site in clinical azole-bound forms between sterol 14alpha-demethylases (CYP51s) from human and Mycobacterium tuberculosis. Matsuura K, Yoshioka S, Tosha T, Hori H, Ishimori K, Kitagawa T, Morishima I, Kagawa N, Waterman MR (2005) J Biol Chem 280: 9088-96 Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography. Podust LM, von Kries JP, Eddine AN, Kim Y, Yermalitskaya LV, Kuehne R, Ouellet H, Warrier T, Alteköster M, Lee JS, Rademann J, Oschkinat H, Kaufmann SH, Waterman MR (2007) Antimicrob Agents Chemother 51: 3915-23 High proportion of heteroresistance in gyrA and gyrB in fluoroquinolone-resistant Mycobacterium tuberculosis clinical isolates. Eilertson B, Maruri F, Blackman A, Herrera M, Samuels DC, Sterling TR (2014) Antimicrob Agents Chemother 58: 3270-5 Fluoroquinolone susceptibility in Mycobacterium tuberculosis after pre-diagnosis exposure to older- versus newer-generation fluoroquinolones. van der Heijden YF, Maruri F, Blackman A, Mitchel E, Bian A, Shintani AK, Eden S, Warkentin JV, Sterling TR (2013) Int J Antimicrob Agents 42: 232-7 Structural requirements for substrate recognition of Mycobacterium tuberculosis 14 alpha-demethylase: implications for sterol biosynthesis. Bellamine A, Mangla AT, Dennis AL, Nes WD, Waterman MR (2001) J Lipid Res 42: 128-36 Fluconazole binding and sterol demethylation in three CYP51 isoforms indicate differences in active site topology. Bellamine A, Lepesheva GI, Waterman MR (2004) J Lipid Res 45: 2000-7 Development of a sarcoidosis murine lung granuloma model using Mycobacterium superoxide dismutase A peptide. Swaisgood CM, Oswald-Richter K, Moeller SD, Klemenc JM, Ruple LM, Farver CF, Drake JM, Culver DA, Drake WP (2011) Am J Respir Cell Mol Biol 44: 166-74 Molecular Analysis of Sarcoidosis Granulomas Reveals Antimicrobial Targets. Rotsinger JE, Celada LJ, Polosukhin VV, Atkinson JB, Drake WP (2016) Am J Respir Cell Mol Biol 55: 128-34 Cellular responses to mycobacterial antigens are present in bronchoalveolar lavage fluid used in the diagnosis of sarcoidosis. Oswald-Richter KA, Culver DA, Hawkins C, Hajizadeh R, Abraham S, Shepherd BE, Jenkins CA, Judson MA, Drake WP (2009) Infect Immun 77: 3740-8 Cellular recognition of Mycobacterium tuberculosis ESAT-6 and KatG peptides in systemic sarcoidosis. Drake WP, Dhason MS, Nadaf M, Shepherd BE, Vadivelu S, Hajizadeh R, Newman LS, Kalams SA (2007) Infect Immun 75: 527-30 High proportion of fluoroquinolone-resistant Mycobacterium tuberculosis isolates with novel gyrase polymorphisms and a gyrA region associated with fluoroquinolone susceptibility. Devasia R, Blackman A, Eden S, Li H, Maruri F, Shintani A, Alexander C, Kaiga A, Stratton CW, Warkentin J, Tang YW, Sterling TR (2012) J Clin Microbiol 50: 1390-6 Nosocomial transmission of a drug-sensitive W-variant Mycobacterium tuberculosis strain among patients with acquired immunodeficiency syndrome in Tennessee. Haas DW, Milton S, Kreiswirth BN, Brinsko VL, Bifani PJ, Schaffner W (1998) Infect Control Hosp Epidemiol 19: 635-9
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.