G protein betagamma subunit-mediated presynaptic inhibition: regulation of exocytotic fusion downstream of Ca2+ entry. Blackmer T, Larsen EC, Takahashi M, Martin TF, Alford S, Hamm HE (2001) Science 292: 293-7 GPCR mediated regulation of synaptic transmission. Betke KM, Wells CA, Hamm HE (2012) Prog Neurobiol 96: 304-21 Interaction of Gbetagamma with RACK1 and other WD40 repeat proteins. Chen S, Spiegelberg BD, Lin F, Dell EJ, Hamm HE (2004) J Mol Cell Cardiol 37: 399-406 Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes. Zurawski Z, Page B, Chicka MC, Brindley RL, Wells CA, Preininger AM, Hyde K, Gilbert JA, Cruz-Rodriguez O, Currie KPM, Chapman ER, Alford S, Hamm HE (2017) J Biol Chem 292: 12165-12177 RACK1 regulates specific functions of Gbetagamma. Chen S, Dell EJ, Lin F, Sai J, Hamm HE (2004) J Biol Chem 279: 17861-8 G betagamma binds histone deacetylase 5 (HDAC5) and inhibits its transcriptional co-repression activity. Spiegelberg BD, Hamm HE (2005) J Biol Chem 280: 41769-76 RACK1 binds to a signal transfer region of G betagamma and inhibits phospholipase C beta2 activation. Chen S, Lin F, Hamm HE (2005) J Biol Chem 280: 33445-52 Regulator of G protein signaling 6 (RGS6) protein ensures coordination of motor movement by modulating GABAB receptor signaling. Maity B, Stewart A, Yang J, Loo L, Sheff D, Shepherd AJ, Mohapatra DP, Fisher RA (2012) J Biol Chem 287: 4972-81 RACK1 regulates directional cell migration by acting on G betagamma at the interface with its effectors PLC beta and PI3K gamma. Chen S, Lin F, Shin ME, Wang F, Shen L, Hamm HE (2008) Mol Biol Cell 19: 3909-22 Gβγ inhibits exocytosis via interaction with critical residues on soluble N-ethylmaleimide-sensitive factor attachment protein-25. Wells CA, Zurawski Z, Betke KM, Yim YY, Hyde K, Rodriguez S, Alford S, Hamm HE (2012) Mol Pharmacol 82: 1136-49 Direct modulation of phospholipase D activity by Gbetagamma. Preininger AM, Henage LG, Oldham WM, Yoon EJ, Hamm HE, Brown HA (2006) Mol Pharmacol 70: 311-8 Gbetagamma interferes with Ca2+-dependent binding of synaptotagmin to the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex. Yoon EJ, Gerachshenko T, Spiegelberg BD, Alford S, Hamm HE (2007) Mol Pharmacol 72: 1210-9 Differential stimulation of insulin secretion by GLP-1 and Kisspeptin-10. Schwetz TA, Reissaus CA, Piston DW (2014) PLoS One 9: e113020 Differential localization of G protein βγ subunits. Betke KM, Rose KL, Friedman DB, Baucum AJ, Hyde K, Schey KL, Hamm HE (2014) Biochemistry 53: 2329-43 G protein betagamma subunits modulate the number and nature of exocytotic fusion events in adrenal chromaffin cells independent of calcium entry. Yoon EJ, Hamm HE, Currie KP (2008) J Neurophysiol 100: 2929-39 Inhibition of Ca2+ channels and adrenal catecholamine release by G protein coupled receptors. Currie KP (2010) Cell Mol Neurobiol 30: 1201-8 G protein modulation of CaV2 voltage-gated calcium channels. Currie KP (2010) Channels (Austin) 4: 497-509
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