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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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- Solution structure of a pleckstrin-homology domain.
Yoon HS, Hajduk PJ, Petros AM, Olejniczak ET, Meadows RP, Fesik SW
(1994) Nature 369: 672-5 - Shape analysis of the histone octamer in solution.
Uberbacher EC, Harp JM, Wilkinson-Singley E, Bunick GJ
(1986) Science 232: 1247-9 - Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution.
Lange OF, Lakomek NA, Farès C, Schröder GF, Walter KF, Becker S, Meiler J, Grubmüller H, Griesinger C, de Groot BL
(2008) Science 320: 1471-5 - Assessing Toxicity of Intravenous Crystalloids in Critically Ill Patients.
Kellum JA, Shaw AD
(2015) JAMA 314: 1695-7 - Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus.
Karimy JK, Zhang J, Kurland DB, Theriault BC, Duran D, Stokum JA, Furey CG, Zhou X, Mansuri MS, Montejo J, Vera A, DiLuna ML, Delpire E, Alper SL, Gunel M, Gerzanich V, Medzhitov R, Simard JM, Kahle KT
(2017) Nat Med 23: 997-1003 - NKCC1 transporter facilitates seizures in the developing brain.
Dzhala VI, Talos DM, Sdrulla DA, Brumback AC, Mathews GC, Benke TA, Delpire E, Jensen FE, Staley KJ
(2005) Nat Med 11: 1205-13 - AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure.
Gurley SB, Riquier-Brison ADM, Schnermann J, Sparks MA, Allen AM, Haase VH, Snouwaert JN, Le TH, McDonough AA, Koller BH, Coffman TM
(2011) Cell Metab 13: 469-475 - The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents.
Carlomagno T, Blommers MJ, Meiler J, Jahnke W, Schupp T, Petersen F, Schinzer D, Altmann KH, Griesinger C
(2003) Angew Chem Int Ed Engl 42: 2511-5 - Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution.
Reese M, Sánchez-Pedregal VM, Kubicek K, Meiler J, Blommers MJ, Griesinger C, Carlomagno T
(2007) Angew Chem Int Ed Engl 46: 1864-8 - The tubulin-bound conformation of discodermolide derived by NMR studies in solution supports a common pharmacophore model for epothilone and discodermolide.
Sánchez-Pedregal VM, Kubicek K, Meiler J, Lyothier I, Paterson I, Carlomagno T
(2006) Angew Chem Int Ed Engl 45: 7388-94 - Visualizing gold nanoparticle uptake in live cells with liquid scanning transmission electron microscopy.
Peckys DB, de Jonge N
(2011) Nano Lett 11: 1733-8 - Antiangiogenic agents protect liver sinusoidal lining cells from cold preservation injury in rat liver transplantation.
Gao W, Washington MK, Bentley RC, Clavien PA
(1997) Gastroenterology 113: 1692-700 - Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice.
Zhang MZ, Yao B, Wang S, Fan X, Wu G, Yang H, Yin H, Yang S, Harris RC
(2011) J Clin Invest 121: 2845-54 - Integrated compensatory network is activated in the absence of NCC phosphorylation.
Grimm PR, Lazo-Fernandez Y, Delpire E, Wall SM, Dorsey SG, Weinman EJ, Coleman R, Wade JB, Welling PA
(2015) J Clin Invest 125: 2136-50 - Rate constants for peroxidation of polyunsaturated fatty acids and sterols in solution and in liposomes.
Xu L, Davis TA, Porter NA
(2009) J Am Chem Soc 131: 13037-44 - Solution NMR spectroscopy of the human vasopressin V2 receptor, a G protein-coupled receptor.
Tian C, Breyer RM, Kim HJ, Karra MD, Friedman DB, Karpay A, Sanders CR
(2005) J Am Chem Soc 127: 8010-1 - Conformation of receptor-bound visual arrestin.
Kim M, Vishnivetskiy SA, Van Eps N, Alexander NS, Cleghorn WM, Zhan X, Hanson SM, Morizumi T, Ernst OP, Meiler J, Gurevich VV, Hubbell WL
(2012) Proc Natl Acad Sci U S A 109: 18407-12 - Solution structure of the antiapoptotic protein bcl-2.
Petros AM, Medek A, Nettesheim DG, Kim DH, Yoon HS, Swift K, Matayoshi ED, Oltersdorf T, Fesik SW
(2001) Proc Natl Acad Sci U S A 98: 3012-7 - Origin and prediction of free-solution interaction studies performed label-free.
Bornhop DJ, Kammer MN, Kussrow A, Flowers RA, Meiler J
(2016) Proc Natl Acad Sci U S A 113: E1595-604 - NMR study of the possible interaction in solution of angiotensin II with a peptide encoded by angiotensin II complementary RNA.
Eaton HL, Austin RE, Fesik SW, Martin SF
(1989) Proc Natl Acad Sci U S A 86: 9767-9 - Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus.
Huang Q, Petros AM, Virgin HW, Fesik SW, Olejniczak ET
(2002) Proc Natl Acad Sci U S A 99: 3428-33 - The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen.
Mogridge J, Cunningham K, Lacy DB, Mourez M, Collier RJ
(2002) Proc Natl Acad Sci U S A 99: 7045-8 - Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor.
Zhou MM, Meadows RP, Logan TM, Yoon HS, Wade WS, Ravichandran KS, Burakoff SJ, Fesik SW
(1995) Proc Natl Acad Sci U S A 92: 7784-8 - Structural insight into HIV-1 capsid recognition by rhesus TRIM5α.
Yang H, Ji X, Zhao G, Ning J, Zhao Q, Aiken C, Gronenborn AM, Zhang P, Xiong Y
(2012) Proc Natl Acad Sci U S A 109: 18372-7 - Renal cortical cyclooxygenase 2 expression is differentially regulated by angiotensin II AT(1) and AT(2) receptors.
Zhang MZ, Yao B, Cheng HF, Wang SW, Inagami T, Harris RC
(2006) Proc Natl Acad Sci U S A 103: 16045-50 - Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules.
Grimm PR, Coleman R, Delpire E, Welling PA
(2017) J Am Soc Nephrol 28: 2597-2606 - Overexpression of OATP1B3 confers apoptotic resistance in colon cancer.
Lee W, Belkhiri A, Lockhart AC, Merchant N, Glaeser H, Harris EI, Washington MK, Brunt EM, Zaika A, Kim RB, El-Rifai W
(2008) Cancer Res 68: 10315-23 - Preference for IgG mAb binding insulin in solution or on surfaces is related to immunoglobulin variable region structures.
Tikhomirov OY, Thomas JW
(1997) J Autoimmun 10: 541-9 - Ferric pyrophosphate citrate administered via dialysate reduces erythropoiesis-stimulating agent use and maintains hemoglobin in hemodialysis patients.
Gupta A, Lin V, Guss C, Pratt R, Ikizler TA, Besarab A
(2015) Kidney Int 88: 1187-94 - Amino acid and albumin losses during hemodialysis.
Ikizler TA, Flakoll PJ, Parker RA, Hakim RM
(1994) Kidney Int 46: 830-7 - Downloadable computer models for maintenance but not acute renal replacement therapy.
Marshall MR, Golper TA
(2006) Kidney Int 70: 1373-4; author reply 1374 - New nuclear magnetic resonance structures and structural methodology.
Chazin WJ
(1991) Curr Opin Biotechnol 2: 520-5 - NKCC1 phosphorylation stimulates neurite growth of injured adult sensory neurons.
Pieraut S, Laurent-Matha V, Sar C, Hubert T, Méchaly I, Hilaire C, Mersel M, Delpire E, Valmier J, Scamps F
(2007) J Neurosci 27: 6751-9 - Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension.
Norlander AE, Saleh MA, Kamat NV, Ko B, Gnecco J, Zhu L, Dale BL, Iwakura Y, Hoover RS, McDonough AA, Madhur MS
(2016) Hypertension 68: 167-74 - Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice.
Kamat NV, Thabet SR, Xiao L, Saleh MA, Kirabo A, Madhur MS, Delpire E, Harrison DG, McDonough AA
(2015) Hypertension 65: 569-76 - Major complications, mortality, and resource utilization after open abdominal surgery: 0.9% saline compared to Plasma-Lyte.
Shaw AD, Bagshaw SM, Goldstein SL, Scherer LA, Duan M, Schermer CR, Kellum JA
(2012) Ann Surg 255: 821-9 - Association between the choice of IV crystalloid and in-hospital mortality among critically ill adults with sepsis*.
Raghunathan K, Shaw A, Nathanson B, Stürmer T, Brookhart A, Stefan MS, Setoguchi S, Beadles C, Lindenauer PK
(2014) Crit Care Med 42: 1585-91
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