Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1. Lim J, Crespo-Barreto J, Jafar-Nejad P, Bowman AB, Richman R, Hill DE, Orr HT, Zoghbi HY (2008) Nature 452: 713-8 Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region. Sutcliffe JS, Nakao M, Christian S, Orstavik KH, Tommerup N, Ledbetter DH, Beaudet AL (1994) Nat Genet 8: 52-8 Sequencing and functional analysis of the SNRPN promoter: in vitro methylation abolishes promoter activity. Huq AH, Sutcliffe JS, Nakao M, Shen Y, Gibbs RA, Beaudet AL (1997) Genome Res 7: 642-8 Identification of a novel paternally expressed transcript adjacent to snRPN in the Prader-Willi syndrome critical region. Ning Y, Roschke A, Christian SL, Lesser J, Sutcliffe JS, Ledbetter DH (1996) Genome Res 6: 742-6 Tissue-specific and allele-specific replication timing control in the imprinted human Prader-Willi syndrome region. Gunaratne PH, Nakao M, Ledbetter DH, Sutcliffe JS, Chinault AC (1995) Genes Dev 9: 808-20 Dyskerin, tRNA genes, and condensin tether pericentric chromatin to the spindle axis in mitosis. Snider CE, Stephens AD, Kirkland JG, Hamdani O, Kamakaka RT, Bloom K (2014) J Cell Biol 207: 189-99 Structural characterization of the fission yeast U5.U2/U6 spliceosome complex. Ohi MD, Ren L, Wall JS, Gould KL, Walz T (2007) Proc Natl Acad Sci U S A 104: 3195-200 Small ribonucleoproteins in Schizosaccharomyces pombe and Yarrowia lipolytica homologous to signal recognition particle. Poritz MA, Siegel V, Hansen W, Walter P (1988) Proc Natl Acad Sci U S A 85: 4315-9 Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast. Wilkinson CR, Dittmar GA, Ohi MD, Uetz P, Jones N, Finley D (2004) Curr Biol 14: 2283-8 Isolation of an essential Schizosaccharomyces pombe gene, prp31(+), that links splicing and meiosis. Bishop DT, McDonald WH, Gould KL, Forsburg SL (2000) Nucleic Acids Res 28: 2214-20 Imprinting analysis of three genes in the Prader-Willi/Angelman region: SNRPN, E6-associated protein, and PAR-2 (D15S225E). Nakao M, Sutcliffe JS, Durtschi B, Mutirangura A, Ledbetter DH, Beaudet AL (1994) Hum Mol Genet 3: 309-15 Influence of antigen organization on the development of lupus autoantibodies. Fatenejad S, Bennett M, Moslehi J, Craft J (1998) Arthritis Rheum 41: 603-12 A minimal spliceosomal complex A recognizes the branch site and polypyrimidine tract. Query CC, McCaw PS, Sharp PA (1997) Mol Cell Biol 17: 2944-53 Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing. McDonald WH, Ohi R, Smelkova N, Frendewey D, Gould KL (1999) Mol Cell Biol 19: 5352-62 Structure and functional implications of a complex containing a segment of U6 RNA bound by a domain of Prp24. Martin-Tumasz S, Reiter NJ, Brow DA, Butcher SE (2010) RNA 16: 792-804 The splicing factor PSF is part of a large complex that assembles in the absence of pre-mRNA and contains all five snRNPs. Peng R, Hawkins I, Link AJ, Patton JG (2006) RNA Biol 3: 69-76 Posttranscriptional regulation of calcitonin/CGRP gene expression. Emeson RB, Yeakley JM, Hedjran F, Merillat N, Lenz HJ, Rosenfeld MG (1992) Ann N Y Acad Sci 657: 18-35 Structure and interactions of the first three RNA recognition motifs of splicing factor prp24. Bae E, Reiter NJ, Bingman CA, Kwan SS, Lee D, Phillips GN, Butcher SE, Brow DA (2007) J Mol Biol 367: 1447-58 SNRPN methylation patterns in germ cell tumors as a reflection of primordial germ cell development. Bussey KJ, Lawce HJ, Himoe E, Shu XO, Heerema NA, Perlman EJ, Olson SB, Magenis RE (2001) Genes Chromosomes Cancer 32: 342-52 A complete YAC contig of the Prader-Willi/Angelman chromosome region (15q11-q13) and refined localization of the SNRPN gene. Mutirangura A, Jayakumar A, Sutcliffe JS, Nakao M, McKinney MJ, Buiting K, Horsthemke B, Beaudet AL, Chinault AC, Ledbetter DH (1993) Genomics 18: 546-52 Resonance assignments for the two N-terminal RNA recognition motifs (RRM) of the S. cerevisiae pre-mRNA processing protein Prp24. Reiter NJ, Lee D, Wang YX, Tonelli M, Bahrami A, Cornilescu CC, Butcher SE (2006) J Biomol NMR 36 Suppl 1: 58 Protein phosphatase 2A family members (PP2A and PP6) associate with U1 snRNP and the spliceosome during pre-mRNA splicing. Kamoun M, Filali M, Murray MV, Awasthi S, Wadzinski BE (2013) Biochem Biophys Res Commun 440: 306-11
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.