Keyword Connections

•  A. Brill

•  Elizabeth Heitman

•  Sten Vermund

Resources

• oMIR013

Communities

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Publications

• Estimation of the warfarin dose with clinical and pharmacogenetic data.
  International Warfarin Pharmacogenetics Consortium, Klein TE, Altman RB, Eriksson N, Gage BF, Kimmel SE, Lee MT, Limdi NA, Page D, Roden DM, Wagner MJ, Caldwell MD, Johnson JA
  (2009) N Engl J Med 360: 753-64
• Genetic determinants of response to warfarin during initial anticoagulation.
  Schwarz UI, Ritchie MD, Bradford Y, Li C, Dudek SM, Frye-Anderson A, Kim RB, Roden DM, Stein CM
  (2008) N Engl J Med 358: 999-1008
• Common genetic determinants of vitamin D insufficiency: a genome-wide association study.
  Wang TJ, Zhang F, Richards JB, Kestenbaum B, van Meurs JB, Berry D, Kiel DP, Streeten EA, Ohlsson C, Koller DL, Peltonen L, Cooper JD, O'Reilly PF, Houston DK, Glazer NL, Vandenput L, Peacock M, Shi J, Rivadeneira F, McCarthy MI, Anneli P, de Boer IH, Mangino M, Kato B, Smyth DJ, Booth SL, Jacques PF, Burke GL, Goodarzi M, Cheung CL, Wolf M, Rice K, Goltzman D, Hidiroglou N, Ladouceur M, Wareham NJ, Hocking LJ, Hart D, Arden NK, Cooper C, Malik S, Fraser WD, Hartikainen AL, Zhai G, Macdonald HM, Forouhi NG, Loos RJ, Reid DM, Hakim A, Dennison E, Liu Y, Power C, Stevens HE, Jaana L, Vasan RS, Soranzo N, Bojunga J, Psaty BM, Lorentzon M, Foroud T, Harris TB, Hofman A, Jansson JO, Cauley JA, Uitterlinden AG, Gibson Q, Järvelin MR, Karasik D, Siscovick DS, Econs MJ, Kritchevsky SB, Florez JC, Todd JA, Dupuis J, Hyppönen E, Spector TD
  (2010) Lancet 376: 180-8
• Decline in pneumonia admissions after routine childhood immunisation with pneumococcal conjugate vaccine in the USA: a time-series analysis.
  Grijalva CG, Nuorti JP, Arbogast PG, Martin SW, Edwards KM, Griffin MR
  (2007) Lancet 369: 1179-86
• A genome-wide linkage and association scan reveals novel loci for autism.
  Weiss LA, Arking DE, Gene Discovery Project of Johns Hopkins & the Autism Consortium, Daly MJ, Chakravarti A
  (2009) Nature 461: 802-8
• Overview of the Alliance for Cellular Signaling.
  Gilman AG, Simon MI, Bourne HR, Harris BA, Long R, Ross EM, Stull JT, Taussig R, Bourne HR, Arkin AP, Cobb MH, Cyster JG, Devreotes PN, Ferrell JE, Fruman D, Gold M, Weiss A, Stull JT, Berridge MJ, Cantley LC, Catterall WA, Coughlin SR, Olson EN, Smith TF, Brugge JS, Botstein D, Dixon JE, Hunter T, Lefkowitz RJ, Pawson AJ, Sternberg PW, Varmus H, Subramaniam S, Sinkovits RS, Li J, Mock D, Ning Y, Saunders B, Sternweis PC, Hilgemann D, Scheuermann RH, DeCamp D, Hsueh R, Lin KM, Ni Y, Seaman WE, Simpson PC, O'Connell TD, Roach T, Simon MI, Choi S, Eversole-Cire P, Fraser I, Mumby MC, Zhao Y, Brekken D, Shu H, Meyer T, Chandy G, Heo WD, Liou J, O'Rourke N, Verghese M, Mumby SM, Han H, Brown HA, Forrester JS, Ivanova P, Milne SB, Casey PJ, Harden TK, Arkin AP, Doyle J, Gray ML, Meyer T, Michnick S, Schmidt MA, Toner M, Tsien RY, Natarajan M, Ranganathan R, Sambrano GR, Participating investigators and scientists of the Alliance for Cellular Signaling
  (2002) Nature 420: 703-6
• Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
  Fox JM, Long F, Edeling MA, Lin H, van Duijl-Richter MKS, Fong RH, Kahle KM, Smit JM, Jin J, Simmons G, Doranz BJ, Crowe JE, Fremont DH, Rossmann MG, Diamond MS
  (2015) Cell 163: 1095-1107
• Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.
  Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT, Cale EM, Chen L, Choi CW, Chuang GY, Doria-Rose NA, Druz A, Georgiev IS, Gorman J, Huang J, Joyce MG, Louder MK, Ma X, McKee K, O'Dell S, Pancera M, Yang Y, Blanchard SC, Mothes W, Burton DR, Koff WC, Connors M, Ward AB, Kwong PD, Mascola JR
  (2016) Science 352: 828-33
• A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses.
  Wec AZ, Nyakatura EK, Herbert AS, Howell KA, Holtsberg FW, Bakken RR, Mittler E, Christin JR, Shulenin S, Jangra RK, Bharrhan S, Kuehne AI, Bornholdt ZA, Flyak AI, Saphire EO, Crowe JE, Aman MJ, Dye JM, Lai JR, Chandran K
  (2016) Science 354: 350-354
• Automated identification of postoperative complications within an electronic medical record using natural language processing.
  Murff HJ, FitzHenry F, Matheny ME, Gentry N, Kotter KL, Crimin K, Dittus RS, Rosen AK, Elkin PL, Brown SH, Speroff T
  (2011) JAMA 306: 848-55
• Influence of patient literacy on the effectiveness of a primary care-based diabetes disease management program.
  Rothman RL, DeWalt DA, Malone R, Bryant B, Shintani A, Crigler B, Weinberger M, Pignone M
  (2004) JAMA 292: 1711-6
• Single versus multiple internal mammary artery grafting for coronary artery bypass: 15-year follow-up of a clinical practice trial.
  Burfeind WR, Glower DD, Wechsler AS, Tuttle RH, Shaw LK, Harrell FE, Rankin JS
  (2004) Circulation 110: II27-35
• Genome-wide association study of Tourette's syndrome.
  Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service SK, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, Davis LK, Han B, Crane J, Moorjani P, Crenshaw AT, Parkin MA, Reus VI, Lowe TL, Rangel-Lugo M, Chouinard S, Dion Y, Girard S, Cath DC, Smit JH, King RA, Fernandez TV, Leckman JF, Kidd KK, Kidd JR, Pakstis AJ, State MW, Herrera LD, Romero R, Fournier E, Sandor P, Barr CL, Phan N, Gross-Tsur V, Benarroch F, Pollak Y, Budman CL, Bruun RD, Erenberg G, Naarden AL, Lee PC, Weiss N, Kremeyer B, Berrío GB, Campbell DD, Cardona Silgado JC, Ochoa WC, Mesa Restrepo SC, Muller H, Valencia Duarte AV, Lyon GJ, Leppert M, Morgan J, Weiss R, Grados MA, Anderson K, Davarya S, Singer H, Walkup J, Jankovic J, Tischfield JA, Heiman GA, Gilbert DL, Hoekstra PJ, Robertson MM, Kurlan R, Liu C, Gibbs JR, Singleton A, North American Brain Expression Consortium, Hardy J, UK Human Brain Expression Database, Strengman E, Ophoff RA, Wagner M, Moessner R, Mirel DB, Posthuma D, Sabatti C, Eskin E, Conti DV, Knowles JA, Ruiz-Linares A, Rouleau GA, Purcell S, Heutink P, Oostra BA, McMahon WM, Freimer NB, Cox NJ, Pauls DL
  (2013) Mol Psychiatry 18: 721-8
• Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus.
  Smith SA, Silva LA, Fox JM, Flyak AI, Kose N, Sapparapu G, Khomandiak S, Khomadiak S, Ashbrook AW, Kahle KM, Fong RH, Swayne S, Doranz BJ, McGee CE, Heise MT, Pal P, Brien JD, Austin SK, Diamond MS, Dermody TS, Crowe JE
  (2015) Cell Host Microbe 18: 86-95
• RePORT International: Advancing Tuberculosis Biomarker Research Through Global Collaboration.
  Hamilton CD, Swaminathan S, Christopher DJ, Ellner J, Gupta A, Sterling TR, Rolla V, Srinivasan S, Karyana M, Siddiqui S, Stoszek SK, Kim P
  (2015) Clin Infect Dis 61Suppl 3: S155-9
• Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapy.
  Li C, Schwarz UI, Ritchie MD, Roden DM, Stein CM, Kurnik D
  (2009) Blood 113: 3925-30
• Anticoagulant and antiplatelet usage associates with mortality among hemodialysis patients.
  Chan KE, Lazarus JM, Thadhani R, Hakim RM
  (2009) J Am Soc Nephrol 20: 872-81
• Warfarin use associates with increased risk for stroke in hemodialysis patients with atrial fibrillation.
  Chan KE, Lazarus JM, Thadhani R, Hakim RM
  (2009) J Am Soc Nephrol 20: 2223-33
• Social cognition in schizophrenia: an NIMH workshop on definitions, assessment, and research opportunities.
  Green MF, Penn DL, Bentall R, Carpenter WT, Gaebel W, Gur RC, Kring AM, Park S, Silverstein SM, Heinssen R
  (2008) Schizophr Bull 34: 1211-20
• Worldwide, mortality risk is high soon after initiation of hemodialysis.
  Robinson BM, Zhang J, Morgenstern H, Bradbury BD, Ng LJ, McCullough KP, Gillespie BW, Hakim R, Rayner H, Fort J, Akizawa T, Tentori F, Pisoni RL
  (2014) Kidney Int 85: 158-65
• A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface.
  Fibriansah G, Tan JL, Smith SA, de Alwis AR, Ng TS, Kostyuchenko VA, Ibarra KD, Wang J, Harris E, de Silva A, Crowe JE, Lok SM
  (2014) EMBO Mol Med 6: 358-71
• An international career development survey of critical care practitioners*.
  Patel MB, Laudanski K, Pandharipande PP
  (2014) Crit Care Med 42: e300-3
• The relationship between delirium duration, white matter integrity, and cognitive impairment in intensive care unit survivors as determined by diffusion tensor imaging: the VISIONS prospective cohort magnetic resonance imaging study*.
  Morandi A, Rogers BP, Gunther ML, Merkle K, Pandharipande P, Girard TD, Jackson JC, Thompson J, Shintani AK, Geevarghese S, Miller RR, Canonico A, Cannistraci CJ, Gore JC, Ely EW, Hopkins RO, VISIONS Investigation, VISualizing Icu SurvivOrs Neuroradiological Sequelae
  (2012) Crit Care Med 40: 2182-9
• Structure of Epstein-Barr virus glycoprotein 42 suggests a mechanism for triggering receptor-activated virus entry.
  Kirschner AN, Sorem J, Longnecker R, Jardetzky TS
  (2009) Structure 17: 223-33
• Flash mob research: a single-day, multicenter, resident-directed study of respiratory rate.
  Semler MW, Stover DG, Copland AP, Hong G, Johnson MJ, Kriss MS, Otepka H, Wang L, Christman BW, Rice TW
  (2013) Chest 143: 1740-1744
• Validation of VA administrative data algorithms for identifying cardiovascular disease hospitalization.
  Niesner K, Murff HJ, Griffin MR, Wasserman B, Greevy R, Grijalva CG, Roumie CL
  (2013) Epidemiology 24: 334-5
• External validation of IASP diagnostic criteria for Complex Regional Pain Syndrome and proposed research diagnostic criteria. International Association for the Study of Pain.
  Bruehl S, Harden RN, Galer BS, Saltz S, Bertram M, Backonja M, Gayles R, Rudin N, Bhugra MK, Stanton-Hicks M
  (1999) Pain 81: 147-54
• Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies.
  Bornholdt ZA, Ndungo E, Fusco ML, Bale S, Flyak AI, Crowe JE, Chandran K, Saphire EO
  (2016) MBio 7: e02154-15
• International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 3: extraprostatic extension, lymphovascular invasion and locally advanced disease.
  Magi-Galluzzi C, Evans AJ, Delahunt B, Epstein JI, Griffiths DF, van der Kwast TH, Montironi R, Wheeler TM, Srigley JR, Egevad LL, Humphrey PA, ISUP Prostate Cancer Group
  (2011) Mod Pathol 24: 26-38
• International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 2: T2 substaging and prostate cancer volume.
  van der Kwast TH, Amin MB, Billis A, Epstein JI, Griffiths D, Humphrey PA, Montironi R, Wheeler TM, Srigley JR, Egevad L, Delahunt B, ISUP Prostate Cancer Group
  (2011) Mod Pathol 24: 16-25
• Consensus report of the international society of gastrointestinal oncology on therapeutic progress in advanced pancreatic cancer.
  Hochster HS, Haller DG, de Gramont A, Berlin JD, Philip PA, Moore MJ, Ajani JA
  (2006) Cancer 107: 676-85
• Src kinase mediates productive endocytic sorting of reovirus during cell entry.
  Mainou BA, Dermody TS
  (2011) J Virol 85: 3203-13
• Mapping the N-terminal residues of Epstein-Barr virus gp42 that bind gH/gL by using fluorescence polarization and cell-based fusion assays.
  Liu F, Marquardt G, Kirschner AN, Longnecker R, Jardetzky TS
  (2010) J Virol 84: 10375-85
• Maturation-dependent human immunodeficiency virus type 1 particle fusion requires a carboxyl-terminal region of the gp41 cytoplasmic tail.
  Jiang J, Aiken C
  (2007) J Virol 81: 9999-10008
• A single-amino-acid polymorphism in Chikungunya virus E2 glycoprotein influences glycosaminoglycan utilization.
  Silva LA, Khomandiak S, Ashbrook AW, Weller R, Heise MT, Morrison TE, Dermody TS
  (2014) J Virol 88: 2385-97
• HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry.
  Zhou J, Price AJ, Halambage UD, James LC, Aiken C
  (2015) J Virol 89: 9068-79
• Transport to late endosomes is required for efficient reovirus infection.
  Mainou BA, Dermody TS
  (2012) J Virol 86: 8346-58
• NPXY motifs in the beta1 integrin cytoplasmic tail are required for functional reovirus entry.
  Maginnis MS, Mainou BA, Derdowski A, Johnson EM, Zent R, Dermody TS
  (2008) J Virol 82: 3181-91
• Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis.
  Hotard AL, Lee S, Currier MG, Crowe JE, Sakamoto K, Newcomb DC, Peebles RS, Plemper RK, Moore ML
  (2015) J Virol 89: 512-22
• Serotonin Receptor Agonist 5-Nonyloxytryptamine Alters the Kinetics of Reovirus Cell Entry.
  Mainou BA, Ashbrook AW, Smith EC, Dorset DC, Denison MR, Dermody TS
  (2015) J Virol 89: 8701-12