Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells. Singh AB, Sharma A, Smith JJ, Krishnan M, Chen X, Eschrich S, Washington MK, Yeatman TJ, Beauchamp RD, Dhawan P (2011) Gastroenterology 141: 2140-53 Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. Dhawan P, Singh AB, Deane NG, No Y, Shiou SR, Schmidt C, Neff J, Washington MK, Beauchamp RD (2005) J Clin Invest 115: 1765-76 Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch-signalling. Pope JL, Bhat AA, Sharma A, Ahmad R, Krishnan M, Washington MK, Beauchamp RD, Singh AB, Dhawan P (2014) Gut 63: 622-34 Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells. Shiou SR, Singh AB, Moorthy K, Datta PK, Washington MK, Beauchamp RD, Dhawan P (2007) Cancer Res 67: 1571-9 Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner. Gowrikumar S, Ahmad R, Uppada SB, Washington MK, Shi C, Singh AB, Dhawan P (2019) Oncogene 38: 5321-5337 HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability. Krishnan M, Singh AB, Smith JJ, Sharma A, Chen X, Eschrich S, Yeatman TJ, Beauchamp RD, Dhawan P (2010) Oncogene 29: 305-12 Trichostatin-A modulates claudin-1 mRNA stability through the modulation of Hu antigen R and tristetraprolin in colon cancer cells. Sharma A, Bhat AA, Krishnan M, Singh AB, Dhawan P (2013) Carcinogenesis 34: 2610-21 Claudin-1 expression confers resistance to anoikis in colon cancer cells in a Src-dependent manner. Singh AB, Sharma A, Dhawan P (2012) Carcinogenesis 33: 2538-47 Claudin-1 overexpression in intestinal epithelial cells enhances susceptibility to adenamatous polyposis coli-mediated colon tumorigenesis. Pope JL, Ahmad R, Bhat AA, Washington MK, Singh AB, Dhawan P (2014) Mol Cancer 13: 167 Smad7 induces hepatic metastasis in colorectal cancer. Halder SK, Rachakonda G, Deane NG, Datta PK (2008) Br J Cancer 99: 957-65 Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells. Singh AB, Harris RC (2004) J Biol Chem 279: 3543-52 Rab25 regulates integrin expression in polarized colonic epithelial cells. Krishnan M, Lapierre LA, Knowles BC, Goldenring JR (2013) Mol Biol Cell 24: 818-31 Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells. Bhat AA, Sharma A, Pope J, Krishnan M, Washington MK, Singh AB, Dhawan P (2012) PLoS One 7: e37174 Modulation of VEGF-induced retinal vascular permeability by peroxisome proliferator-activated receptor-β/δ. Suarez S, McCollum GW, Bretz CA, Yang R, Capozzi ME, Penn JS (2014) Invest Ophthalmol Vis Sci 55: 8232-40 Regulation of metastasis in colorectal adenocarcinoma: a collision between development and tumor biology. Smith JJ, Deane NG, Dhawan P, Beauchamp RD (2008) Surgery 144: 353-66 Biophysical characterization of interactions between the C-termini of peripheral nerve claudins and the PDZ₁ domain of zonula occludens. Wu J, Peng D, Zhang Y, Lu Z, Voehler M, Sanders CR, Li J (2015) Biochem Biophys Res Commun 459: 87-93
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