Oral erythromycin and the risk of sudden death from cardiac causes. Ray WA, Murray KT, Meredith S, Narasimhulu SS, Hall K, Stein CM (2004) N Engl J Med 351: 1089-96 ATP serves as a negative feedback inhibitor of voltage-gated Ca2+ channel currents in cultured bovine adrenal chromaffin cells. Currie KP, Fox AP (1996) Neuron 16: 1027-36 Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation. Hermanson DJ, Hartley ND, Gamble-George J, Brown N, Shonesy BC, Kingsley PJ, Colbran RJ, Reese J, Marnett LJ, Patel S (2013) Nat Neurosci 16: 1291-8 Trends in antihypertensive drug advertising, 1985-1996. Wang TJ, Ausiello JC, Stafford RS (1999) Circulation 99: 2055-7 Release of nitrogen oxides from cultured bovine aortic endothelial cells is not impaired by calcium channel antagonists. Mügge A, Peterson T, Harrison DG (1991) Circulation 83: 1404-9 Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT trials. Holtkamp FA, de Zeeuw D, de Graeff PA, Laverman GD, Berl T, Remuzzi G, Packham D, Lewis JB, Parving HH, Lambers Heerspink HJ (2011) Eur Heart J 32: 1493-9 L-type voltage-gated Ca2+ channels modulate expression of smooth muscle differentiation marker genes via a rho kinase/myocardin/SRF-dependent mechanism. Wamhoff BR, Bowles DK, McDonald OG, Sinha S, Somlyo AP, Somlyo AV, Owens GK (2004) Circ Res 95: 406-14 The role of dynamic palmitoylation in Ca2+ channel inactivation. Hurley JH, Cahill AL, Currie KP, Fox AP (2000) Proc Natl Acad Sci U S A 97: 9293-8 Phase I and pharmacokinetic study of a micronized formulation of carboxyamidotriazole, a calcium signal transduction inhibitor: toxicity, bioavailability and the effect of food. Berlin J, Tutsch KD, Arzoomanian RZ, Alberti D, Binger K, Feierabend C, Dresen A, Marnocha R, Pluda J, Wilding G (2002) Clin Cancer Res 8: 86-94 G-proteins modulate cumulative inactivation of N-type (Cav2.2) calcium channels. McDavid S, Currie KP (2006) J Neurosci 26: 13373-83 Comparison of N- and P/Q-type voltage-gated calcium channel current inhibition. Currie KP, Fox AP (1997) J Neurosci 17: 4570-9 Blood pressure control, drug therapy, and kidney disease. Contreras G, Greene T, Agodoa LY, Cheek D, Junco G, Dowie D, Lash J, Lipkowitz M, Miller ER, Ojo A, Sika M, Wilkening B, Toto RD, African American Study of Kidney Disease and Hypertension Study Group Investigators (2005) Hypertension 46: 44-50 Blood pressure reduction and tissue-type plasminogen activator release. Brown NJ (2006) Hypertension 47: 648-9 Parathyroid Hormone and the Use of Diuretics and Calcium-Channel Blockers: The Multi-Ethnic Study of Atherosclerosis. Zaheer S, de Boer I, Allison M, Brown JM, Psaty BM, Robinson-Cohen C, Ix JH, Kestenbaum B, Siscovick D, Vaidya A (2016) J Bone Miner Res 31: 1137-45 Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P-450 IIIA4. Guengerich FP, Brian WR, Iwasaki M, Sari MA, Bäärnhielm C, Berntsson P (1991) J Med Chem 34: 1838-44 Small Molecule Inhibitor Screen Reveals Calcium Channel Signaling as a Mechanistic Mediator of TcdB-Induced Necrosis. Farrow MA, Chumber NM, Bloch SC, King M, Moton-Melancon K, Shupe J, Washington MK, Spiller BW, Lacy DB (2020) ACS Chem Biol 15: 1212-1221 Increased blood flow induces oxidative stress through an endothelium- and nitric oxide-independent mechanism. Fong P, Stafforini DM, Brown NJ, Pretorius M (2010) Free Radic Biol Med 49: 301-5 Pain management in fibromyalgia. Crofford LJ (2008) Curr Opin Rheumatol 20: 246-50 Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass. Hilliard FA, Steele DS, Laver D, Yang Z, Le Marchand SJ, Chopra N, Piston DW, Huke S, Knollmann BC (2010) J Mol Cell Cardiol 48: 293-301 Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes. Chang SW, McDonough CW, Gong Y, Johnson TA, Tsunoda T, Gamazon ER, Perera MA, Takahashi A, Tanaka T, Kubo M, Pepine CJ, Johnson JA, Cooper-DeHoff RM (2018) Pharmacogenomics J 18: 106-112 Prognostic value of acute vasodilator response in pulmonary arterial hypertension: beyond the "classic" responders. Halliday SJ, Hemnes AR, Robbins IM, Pugh ME, Zhao DX, Piana RN, Fong PP, Brittain EL (2015) J Heart Lung Transplant 34: 312-8 Nonantiarrhythmic drug therapy for atrial fibrillation. Murray KT, Mace LC, Yang Z (2007) Heart Rhythm 4: S88-90 No association between calcium channel blocker use and confirmed bleeding peptic ulcer disease. Smalley WE, Ray WA, Daugherty JR, Griffin MR (1998) Am J Epidemiol 148: 350-4 Functional analysis of the purified anandamide-generating phospholipase D as a member of the metallo-beta-lactamase family. Wang J, Okamoto Y, Morishita J, Tsuboi K, Miyatake A, Ueda N (2006) J Biol Chem 281: 12325-35 Multiple modes of ryanodine receptor 2 inhibition by flecainide. Mehra D, Imtiaz MS, van Helden DF, Knollmann BC, Laver DR (2014) Mol Pharmacol 86: 696-706 The bioelectrical basis and validity of gastrointestinal extracellular slow wave recordings. Angeli TR, Du P, Paskaranandavadivel N, Janssen PW, Beyder A, Lentle RG, Bissett IP, Cheng LK, O'Grady G (2013) J Physiol 591: 4567-79 Calcium channel blockers as drug repurposing candidates for gestational diabetes: Mining large scale genomic and electronic health records data to repurpose medications. Goldstein JA, Bastarache LA, Denny JC, Roden DM, Pulley JM, Aronoff DM (2018) Pharmacol Res 130: 44-51 Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury. Yang Y, Yang H, Wang Z, Varadaraj K, Kumari SS, Mergler S, Okada Y, Saika S, Kingsley PJ, Marnett LJ, Reinach PS (2013) Cell Signal 25: 501-11 Clevidipine, an intravenous dihydropyridine calcium channel blocker, is safe and effective for treatment of patients with acute severe hypertension answers to the march 2009 journal club questions. Barrett TW, Schriger DL (2009) Ann Emerg Med 54: 301-7 Effect of manganese (II) bis(glycinate)dichloride on Ca2+ channel function in cultured chick atrial cells. Tan W, Barnett JV, Hehn GM, Quay SC, Galper JB (1991) Toxicology 68: 63-73 Tocolytic treatment for the management of preterm labor: a review of the evidence. Berkman ND, Thorp JM, Lohr KN, Carey TS, Hartmann KE, Gavin NI, Hasselblad V, Idicula AE (2003) Am J Obstet Gynecol 188: 1648-59 Differential CaMKII regulation by voltage-gated calcium channels in the striatum. Pasek JG, Wang X, Colbran RJ (2015) Mol Cell Neurosci 68: 234-43 Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study. Irvin MR, Lynch AI, Kabagambe EK, Tiwari HK, Barzilay JI, Eckfeldt JH, Boerwinkle E, Davis BR, Ford CE, Arnett DK (2010) J Hypertens 28: 2076-83 Use of calcium antagonists in renal patients: therapeutic benefit or medical malpractice? Nigbor DA, Lewis JB (2003) Curr Hypertens Rep 5: 430-6 Hypertension management: special considerations in chronic kidney disease patients. Smith JP, Lewis JB (2004) Curr Hypertens Rep 6: 462-8 L-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins. Maddala R, Nagendran T, de Ridder GG, Schey KL, Rao PV (2013) PLoS One 8: e64676 "Slow" Voltage-Dependent Inactivation of CaV2.2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA). Zhu L, McDavid S, Currie KP (2015) PLoS One 10: e0134117 High-Throughput Screening of Myometrial Calcium-Mobilization to Identify Modulators of Uterine Contractility. Herington JL, Swale DR, Brown N, Shelton EL, Choi H, Williams CH, Hong CC, Paria BC, Denton JS, Reese J (2015) PLoS One 10: e0143243 Hypertension and the coronary circulation. With special attention to endothelial regulation. Harrison DG, Treasure CB, Mügge A, Dellsperger KC, Lamping KG (1991) Am J Hypertens 4: 454S-459S 2-APB protects against liver ischemia-reperfusion injury by reducing cellular and mitochondrial calcium uptake. Nicoud IB, Knox CD, Jones CM, Anderson CD, Pierce JM, Belous AE, Earl TM, Chari RS (2007) Am J Physiol Gastrointest Liver Physiol 293: G623-30
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