A TALE nuclease architecture for efficient genome editing. Miller JC, Tan S, Qiao G, Barlow KA, Wang J, Xia DF, Meng X, Paschon DE, Leung E, Hinkley SJ, Dulay GP, Hua KL, Ankoudinova I, Cost GJ, Urnov FD, Zhang HS, Holmes MC, Zhang L, Gregory PD, Rebar EJ (2011) Nat Biotechnol 29: 143-8 PIQ-ing into chromatin architecture. Rieck S, Wright C (2014) Nat Biotechnol 32: 138-40 Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing. Tsai SQ, Wyvekens N, Khayter C, Foden JA, Thapar V, Reyon D, Goodwin MJ, Aryee MJ, Joung JK (2014) Nat Biotechnol 32: 569-76 The Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability. Dungrawala H, Rose KL, Bhat KP, Mohni KN, Glick GG, Couch FB, Cortez D (2015) Mol Cell 59: 998-1010 Preliminary findings of antistreptococcal antibody titers and basal ganglia volumes in tic, obsessive-compulsive, and attention deficit/hyperactivity disorders. Peterson BS, Leckman JF, Tucker D, Scahill L, Staib L, Zhang H, King R, Cohen DJ, Gore JC, Lombroso P (2000) Arch Gen Psychiatry 57: 364-72 HLA-DR typing "at the DNA level": RFLPs and subtypes detected with a DR beta cDNA probe. Cox NJ, Mela AP, Zmijewski CM, Spielman RS (1988) Am J Hum Genet 43: 954-63 Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions. Wang F, DeMuro NE, Elmquist CE, Stover JS, Rizzo CJ, Stone MP (2006) J Am Chem Soc 128: 10085-95 Selective photochemical treatment of oestrogen receptor in a Xenopus liver extract destroys hormone binding and transcriptional activation but not DNA binding. Cridland NA, Wright CV, McKenzie EA, Knowland J (1990) EMBO J 9: 1859-66 Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45. Zhang J, Liu X, Scherer DC, van Kaer L, Wang X, Xu M (1998) Proc Natl Acad Sci U S A 95: 12480-5 Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system. Jao LE, Wente SR, Chen W (2013) Proc Natl Acad Sci U S A 110: 13904-9 Dynamic alterations in the conformation of the Ifng gene region during T helper cell differentiation. Eivazova ER, Aune TM (2004) Proc Natl Acad Sci U S A 101: 251-6 DNA topoisomerase IIalpha interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution. Durrieu F, Samejima K, Fortune JM, Kandels-Lewis S, Osheroff N, Earnshaw WC (2000) Curr Biol 10: 923-6 A Helicobacter pylori restriction endonuclease-replacing gene, hrgA, is associated with gastric cancer in Asian strains. Ando T, Wassenaar TM, Peek RM, Aras RA, Tschumi AI, van Doorn LJ, Kusugami K, Blaser MJ (2002) Cancer Res 62: 2385-9 Analysis of the PvuII restriction fragment-length polymorphism and exon structure of the estrogen receptor gene in breast cancer and peripheral blood. Yaich L, Dupont WD, Cavener DR, Parl FF (1992) Cancer Res 52: 77-83 Apa I and Sst I RFLPs at the insulin-like growth factor II (IGF2) locus on chromosome 11. Xiang K, Cox NJ, Bell GI (1988) Nucleic Acids Res 16: 3599 FnuD II RFLP at the human dopamine-beta-hydroxylase (D beta H) locus. Perry SE, Phillips JA, Robertson D (1991) Nucleic Acids Res 19: 1162 DNA associated with hyperacetylated histone is preferentially digested by DNase I. Sealy L, Chalkley R (1978) Nucleic Acids Res 5: 1863-76 Four RFLPs of the human insulin receptor gene: PstI, KpnI, RsaI (2 RFLPs). Cox NJ, Spielman RS, Kahn CR, Müller-Wieland D, Kriauciunas KM, Taub R (1988) Nucleic Acids Res 16: 8204 Base-displaced intercalation of the 2-amino-3-methylimidazo[4,5-f]quinolone N2-dG adduct in the NarI DNA recognition sequence. Stavros KM, Hawkins EK, Rizzo CJ, Stone MP (2014) Nucleic Acids Res 42: 3450-63 Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs. Patra A, Harp J, Pallan PS, Zhao L, Abramov M, Herdewijn P, Egli M (2013) Nucleic Acids Res 41: 2689-97 A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. Mussolino C, Morbitzer R, Lütge F, Dannemann N, Lahaye T, Cathomen T (2011) Nucleic Acids Res 39: 9283-93 Bgl II RFLP at the human erythrocyte/HepG2-type glucose transporter (GLUT) locus on chromosome 1. Xiang K, Cox NJ, Karam JH, Bell GI (1987) Nucleic Acids Res 15: 9101 Polymorphisms in ER-alpha gene interact with estrogen receptor status in breast cancer survival. Boyapati SM, Shu XO, Ruan ZX, Cai Q, Smith JR, Wen W, Gao YT, Zheng W (2005) Clin Cancer Res 11: 1093-8 Genetic linkage studies of thyroid peroxidase (TPO) gene in families with TPO deficiency. Mangklabruks A, Billerbeck AE, Wajchenberg B, Knobel M, Cox NJ, DeGroot LJ, Medeiros-Neto G (1991) J Clin Endocrinol Metab 72: 471-6 Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs. Pallan PS, Allerson CR, Berdeja A, Seth PP, Swayze EE, Prakash TP, Egli M (2012) Chem Commun (Camb) 48: 8195-7 Amino acid and nucleotide sequences of variable regions of mouse immunoglobulin light chains of the lambda 3-subtype. Reilly EB, Reilly RM, Breyer RM, Sauer RT, Eisen HN (1984) J Immunol 133: 471-5 A lipopolysaccharide-induced DNA-binding protein for a class II gene in B cells is distinct from NF-kappa B. Gravallese EM, Boothby MR, Smas CM, Glimcher LH (1989) Mol Cell Biol 9: 3184-92 Sequences downstream of the transcription initiation site modulate the activity of the murine dihydrofolate reductase promoter. Farnham PJ, Means AL (1990) Mol Cell Biol 10: 1390-8 Transcription initiation from the dihydrofolate reductase promoter is positioned by HIP1 binding at the initiation site. Means AL, Farnham PJ (1990) Mol Cell Biol 10: 653-61 Cell-type-specific control elements of the lymphotropic papovavirus enhancer. Erselius JR, Jostes B, Hatzopoulos AK, Mosthaf L, Gruss P (1990) J Virol 64: 1657-66 Restriction-modification system differences in Helicobacter pylori are a barrier to interstrain plasmid transfer. Ando T, Xu Q, Torres M, Kusugami K, Israel DA, Blaser MJ (2000) Mol Microbiol 37: 1052-65 Regulation of phosphoenolpyruvate carboxykinase gene expression by insulin. Use of the stable transfection approach to locate an insulin responsive sequence. Forest CD, O'Brien RM, Lucas PC, Magnuson MA, Granner DK (1990) Mol Endocrinol 4: 1302-10 Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo[4,5-f]quinoline but not the C8 adduct at the NarI G3 site. Choi JY, Stover JS, Angel KC, Chowdhury G, Rizzo CJ, Guengerich FP (2006) J Biol Chem 281: 25297-306 Modulation of DNA fragmentation factor 40 nuclease activity by poly(ADP-ribose) polymerase-1. West JD, Ji C, Marnett LJ (2005) J Biol Chem 280: 15141-7 Purification and characterization of a transcription factor which appears to regulate cAMP responsiveness of the human CYP21B gene. Kagawa N, Waterman MR (1992) J Biol Chem 267: 25213-9 Identification and purification of a yeast transcriptional trans-activator. The yeast homolog of the Rous sarcoma virus internal enhancer binding factor. Karnitz L, Poon D, Weil PA, Chalkley R (1990) J Biol Chem 265: 6131-8 Purification and in vitro DNA-binding specificity of the Bacillus subtilis phage phi 105 repressor. Van Kaer L, Van Montagu M, Dhaese P (1989) J Biol Chem 264: 14784-91 The spindle pole body protein Cdc11p links Sid4p to the fission yeast septation initiation network. Tomlin GC, Morrell JL, Gould KL (2002) Mol Biol Cell 13: 1203-14 The largest (70 kDa) product of the bacteriophage T4 DNA terminase gene 17 binds to single-stranded DNA segments and digests them towards junctions with double-stranded DNA. Franklin JL, Haseltine D, Davenport L, Mosig G (1998) J Mol Biol 277: 541-57
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.