Prenatal exposure to drugs: effects on brain development and implications for policy and education. Thompson BL, Levitt P, Stanwood GD (2009) Nat Rev Neurosci 10: 303-12 Natural killer cells determine the outcome of B cell-mediated autoimmunity. Shi FD, Wang HB, Li H, Hong S, Taniguchi M, Link H, Van Kaer L, Ljunggren HG (2000) Nat Immunol 1: 245-51 Direct contact between sympathetic neurons and rat cardiac myocytes in vitro increases expression of functional calcium channels. Ogawa S, Barnett JV, Sen L, Galper JB, Smith TW, Marsh JD (1992) J Clin Invest 89: 1085-93 Immunohistochemical localization of a neuronal nicotinic acetylcholine receptor in mammalian brain. Deutch AY, Holliday J, Roth RH, Chun LL, Hawrot E (1987) Proc Natl Acad Sci U S A 84: 8697-701 Nicotine and networks: Potential for enhancement of mood and cognition in late-life depression. Gandelman JA, Newhouse P, Taylor WD (2018) Neurosci Biobehav Rev 84: 289-298 AZD3480, a novel nicotinic receptor agonist, for the treatment of attention-deficit/hyperactivity disorder in adults. Potter AS, Dunbar G, Mazzulla E, Hosford D, Newhouse PA (2014) Biol Psychiatry 75: 207-14 Muscarinic and nicotinic acetylcholine receptor agonists and allosteric modulators for the treatment of schizophrenia. Jones CK, Byun N, Bubser M (2012) Neuropsychopharmacology 37: 16-42 Nicotine impairs spatial working memory while leaving spatial attention intact. Park S, Knopick C, McGurk S, Meltzer HY (2000) Neuropsychopharmacology 22: 200-9 Developmental consequences of fetal exposure to drugs: what we know and what we still must learn. Ross EJ, Graham DL, Money KM, Stanwood GD (2015) Neuropsychopharmacology 40: 61-87 Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial. Newhouse P, Kellar K, Aisen P, White H, Wesnes K, Coderre E, Pfaff A, Wilkins H, Howard D, Levin ED (2012) Neurology 78: 91-101 Presynaptic Neuronal Nicotinic Receptors Differentially Shape Select Inputs to Auditory Thalamus and Are Negatively Impacted by Aging. Sottile SY, Hackett TA, Cai R, Ling L, Llano DA, Caspary DM (2017) J Neurosci 37: 11377-11389 Uncoupling of the baroreflex by N(N)-cholinergic blockade in dissecting the components of cardiovascular regulation. Shannon JR, Jordan J, Black BK, Costa F, Robertson D (1998) Hypertension 32: 101-7 N(N)-nicotinic blockade as an acute human model of autonomic failure. Jordan J, Shannon JR, Black BK, Lance RH, Squillante MD, Costa F, Robertson D (1998) Hypertension 31: 1178-84 Identification of skin as a major site of prostaglandin D2 release following oral administration of niacin in humans. Morrow JD, Awad JA, Oates JA, Roberts LJ (1992) J Invest Dermatol 98: 812-5 Dopamine receptor genes (DRD2, DRD3 and DRD4) and gene-gene interactions associated with smoking-related behaviors. Vandenbergh DJ, O'Connor RJ, Grant MD, Jefferson AL, Vogler GP, Strasser AA, Kozlowski LT (2007) Addict Biol 12: 106-16 Potentiation of Helicobacter pylori vacuolating toxin activity by nicotine and other weak bases. Cover TL, Vaughn SG, Cao P, Blaser MJ (1992) J Infect Dis 166: 1073-8 Transdermal Nicotine for the Treatment of Mood and Cognitive Symptoms in Nonsmokers With Late-Life Depression. Gandelman JA, Kang H, Antal A, Albert K, Boyd BD, Conley AC, Newhouse P, Taylor WD (2018) J Clin Psychiatry 79: Maternal smoking, alcohol drinking, caffeine consumption, and fetal growth: results from a prospective study. Shu XO, Hatch MC, Mills J, Clemens J, Susser M (1995) Epidemiology 6: 115-20 Developmental nicotine exposure induced alterations in behavior and glutamate receptor function in hippocampus. Parameshwaran K, Buabeid MA, Karuppagounder SS, Uthayathas S, Thiruchelvam K, Shonesy B, Dityatev A, Escobar MC, Dhanasekaran M, Suppiramaniam V (2012) Cell Mol Life Sci 69: 829-41 Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence. Sidique S, Dhanya RP, Sheffler DJ, Nickols HH, Yang L, Dahl R, Mangravita-Novo A, Smith LH, D'Souza MS, Semenova S, Conn PJ, Markou A, Cosford ND (2012) J Med Chem 55: 9434-45 Effects of nicotinic stimulation on cognitive performance. Newhouse PA, Potter A, Singh A (2004) Curr Opin Pharmacol 4: 36-46 Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells. Proskocil BJ, Sekhon HS, Jia Y, Savchenko V, Blakely RD, Lindstrom J, Spindel ER (2004) Endocrinology 145: 2498-506 A novel signaling pathway: fibroblast nicotinic receptor alpha1 binds urokinase and promotes renal fibrosis. Zhang G, Kernan KA, Thomas A, Collins S, Song Y, Li L, Zhu W, Leboeuf RC, Eddy AA (2009) J Biol Chem 284: 29050-64 Functional brain imaging of nicotinic effects on higher cognitive processes. Newhouse PA, Potter AS, Dumas JA, Thiel CM (2011) Biochem Pharmacol 82: 943-51 Choline transporter hemizygosity results in diminished basal extracellular dopamine levels in nucleus accumbens and blunts dopamine elevations following cocaine or nicotine. Dong Y, Dani JA, Blakely RD (2013) Biochem Pharmacol 86: 1084-8 Cognition as a therapeutic target in late-life depression: potential for nicotinic therapeutics. Zurkovsky L, Taylor WD, Newhouse PA (2013) Biochem Pharmacol 86: 1133-44 Role of nicotinic and estrogen signaling during experimental acute and chronic bladder inflammation. Martinez-Ferrer M, Iturregui JM, Uwamariya C, Starkman J, Sharif-Afshar AR, Suzuki K, Visedsindh W, Matusik RJ, Dmochowski RR, Bhowmick NA (2008) Am J Pathol 172: 59-67 Smoking and mechanisms of cardiovascular control. Robertson D, Tseng CJ, Appalsamy M (1988) Am Heart J 115: 258-63 Prostaglandin EP(1) receptor subtype selectivity takes shape. Breyer RM (2001) Mol Pharmacol 59: 1357-9 A gene expression fingerprint of C. elegans embryonic motor neurons. Fox RM, Von Stetina SE, Barlow SJ, Shaffer C, Olszewski KL, Moore JH, Dupuy D, Vidal M, Miller DM (2005) BMC Genomics 6: 42 Nicotinic versus muscarinic blockade alters verbal working memory-related brain activity in older women. Dumas JA, Saykin AJ, McDonald BC, McAllister TW, Hynes ML, Newhouse PA (2008) Am J Geriatr Psychiatry 16: 272-82 Manipulation of nicotinic acetylcholine receptors differentially affects behavioral inhibition in human subjects with and without disordered baseline impulsivity. Potter AS, Bucci DJ, Newhouse PA (2012) Psychopharmacology (Berl) 220: 331-40
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.