The Goldilocks effect. Boothby M, Williams CL (2012) Sci Transl Med 4: 163fs42 T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-site. Tong Y, Aune T, Boothby M (2005) Proc Natl Acad Sci U S A 102: 2034-9 Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2. Young JI, Hong EP, Castle JC, Crespo-Barreto J, Bowman AB, Rose MF, Kang D, Richman R, Johnson JM, Berget S, Zoghbi HY (2005) Proc Natl Acad Sci U S A 102: 17551-8 mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome. Gogliotti RG, Senter RK, Rook JM, Ghoshal A, Zamorano R, Malosh C, Stauffer SR, Bridges TM, Bartolome JM, Daniels JS, Jones CK, Lindsley CW, Conn PJ, Niswender CM (2016) Hum Mol Genet 25: 1990-2004
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.